Sobrerol significantly improves paediatric secretory otitis media 30 children aged 5-10 years with secretory otitis media received sobrerol ('Sobrepin') , a mucolytic agent, 40mg/3ml daily, by Inhalation, for 10 days . Nasal obstruction, earache and deafness were significantly improved. Impedance values were improved in 70% of patients, indicating improved ventilation function . By study end 5 (16.7%) patients were considered cured . Sobrerol was well tolerated . Bellussi L, Bernocchl D, Ciferro G, Manini G, Passali D. Sobrerol in lhe treatment of secretory otitis media In childhood Journal of International Medical Research 17' 277·286, May·Jun 1989 1003

14

INPHARMA" g Sap 19a9

0156·2703/ 89/ 0909·0014 / 0$0100/ 0 © ADIS Press