Special Report Mammalian Genome 3: 300-430, 1992

9 Springer-Verlag New York Inc. 1992

Mouse DNA clones and probes Janan T. Eppig The Jackson Laboratory, Bar Harbor, Maine 04609, USA Received May 11, 1992

A database of mouse clones and probes (Musprob) is maintained in a Fourth Dimension database on the Macintosh computer. This listing is a subset of that database information. The fields that are contained in the full database are as follows: (1) for each probe/ clone: probe/clone name and "aliases," gene or DNA segment derivation of probe, region (of gene) covered, EC number, chromosomal location, probe origin (species, strain, tissue), type (for example, cDNA), copy number per genome, and probe characteristics (vector, host, insertion site, insert size); and (2) for each reference pertaining to a probe/clone: restriction map information given for the probe/clone (y/n), sequenced (y/n), GenBank/EMBL number, restriction fragment length variation (RFLV) detected (gene, probe, endonuclease, allele, fragment sizes, strains typed), endonucleases tested with no RFLV, holder, notes/ comments, and literature citation. The following pages contain: (1) A list of major additions and changes since the last published version of this mouse DNA clones and probes summary (Mouse Genome 89: 593-791, 199I). Included in the tabulated changes are additional loci which now have associated probes/clones (Table 1), locus symbols that have been changed by the Mouse Gene Nomenclature Committee (Table 2a), and loci whose location on the linkage map has been established or changed since a

previous report (Table 2b). (2) Map of mouse loci for which probes/clones are listed (Fig. 1). This linkage map of the mouse contains only those loci that appear in the list of probes and clones. Comments about the map appear m the legend. (3) List of mouse DNA clones and probes (Table 3). For each entry, the list contains the chromosome assignment, locus symbol, locus name, probe name, RFLV ( " + " indicates known RFLV), contact person or first author, and reference. The list is arranged numerically by chromosome and the loci are listed alphabetically within each chromosome list. Loci and probes that have not been assigned to a specific chromosome and probes that detect multiple loci are listed at the end. Conventions are listed in the table footnote. The database which forms the foundation for this listing is continually being updated. We would appreciate receiving contributed information for the database. We also encourage you to communicate any errors or omissions you observe. Your assistance will help keep this list current and complete. Acknowledgments. I thank Michael Kosowsky, Dan Farley, Janice Ormsby, Moyha Lennon-Pierce, Steven Rockwood, and Marijo Vollmer for their help in preparing this document. The production of this listing was supported by National Institutes of Health grant HG00330.

J.T, Eppig: Clones and Probes

301

Table 1. Major additions and changes since the last edition (Mouse Genome 89: 593-791, 1991). New Lod in the Mouse that now h~v~ amoeiated ~ o n e s Chr Amh.rsl Cd3n Cd28 Cd34 "D1HI8 "DIH37" "DIH46 . . . . "D1H49" D1Rti2 Fcrg3 Gas. 10 Gsh-4 l gfbp. 2 "lllr.2" Mintb Mmv-14

1 Mpmv-32 Mpmv-34 Mpm~-35 Mpmv-37 Mpmv-42 Mtap-4 Nscl" Pmv-45 "Snrpla-rM" "Ssa . . . .

Bmi.l "D2HI6" "D2H28" "D2H43" D2McCI DIx-I His-I Hox-4.9 lllrn Kin" "Nk~-2.2 " Pax-6 P~Ja Rag-1 Rag-2 Xmv-48

Ctu- 11

Chr 12

"DI1H38" "DllHaml" DIIMeC1 D11Nds2 Ga~ Gas-3 Hmgi-rM

Amh.rs4 iv Mmv.18 Synd

adt Amh-rs2 "Dl3Haml" DI3McCI Mpmv-33 SrdSa-1 Xmv-55

Acs" Ache Acvba Acvbb Acvr Acvr2b "Apex" Amh-rs3 Amh.rs5 Amh,rs6 Amh,rs8 Adss~ "AO~-4'" Bla-I "Bup" Clqa Cdl9 "Centa" "Ck-psl . . . . "Ck-ps2" "Ck-ps3" Cftr C li CoOa-2 CollOa-I DONds5 DONds29 DONds32 DONds33 DONds34 DONdy35

DONds36 DONds37 Dlx-2 Drd-2 "Ed~" Emi- t Ercc-3 Fgfr-I Fgfr-2 Fgfr-4 "Fkbp" Ftk-2 Folbp-I Folbp-2 Ftll Gabrb-2 Galbp Gas,5 Gbp-2" "Gir" Gja-3 Gja-4 Glut-7 "Gnal5" Gah,5 "Gstc-2" "Hcph" "Hgmi-c" Hox,8.1 Hox-9 Hpl

My,t4 Mmv-16 Mmv,17 Pmv-58 Xmmv-77 Xmv-47 Xmv-49

s Y "B3 . . . . "Sx l " "T5" Ube-2 Ube-3

(Ynr3 Ank.2 "D3H44" D3McCI

F~f-2 Gbp-I ~fol

Qlr 4 Cycb "D4H30" "D4H3Y" "D4Haml" D4McC,1 D4McC2 D4Ndd IMSmh6b Mmv-15 Mpmv.36 Orm-3 Plc Prav.5 l

Chr 5 Cncg "DSGotl" "D5H6" "DSHI3" "D5H17" Fgf-5 FIk- I Gsh-I Gsh-2 Gsh-3 Mmv-19 Pal-1 Pray.40 Pray-53 Sri

Chr 6 Act-4 D6NdM Glut-3 Gnb-3 Hmgl-rs2 Hox-l.8 H ox- l.9 Hox-l.ll Mglap Pim-lrsl Vin-1

Chr 7 Bcl-3 "DTCw2P" "'D7Cw2D" "DTCw11P" "DTCw112D" "DTHS" D7McC1 D7McC2 DTRn] D7Rn2 'Tab" "Fosb~ Gabrb.3 "'Gclrpo'

Clu" 14

g--'hr15

Chr 16

Chr 17

Chrl8

Amh-rs7 Cyp l l b-1 Ho:~-3.7 Hox-3.8 R2rb Krt-2.6 Pray-48 Pray-50 Pray-54

Apod "l)16H22" D16McC1 D16Smh250 D16Smh580 Gas-4 H ~r)a Hr Top]-ps2 Xmv-50

Bat-1 Bat-2 Bat-4 Bat.5 "D17H40" D17Kenl Grr H-2M3 Pcna-tx~2 Pim-lrs2 Pray-57 Tctex-2 Tctex-3 Tctex-4 Tctex-5 Tctex-6 Tetex-7 Thbs-2 Xmv-57

Pray.20 Ptpt

"Hsfl" "Hsf2" 'Td~. . . .

Muc- I Myf'5 Myf6" 'Tnreabp" "Nkx-2.3" lrf-1 "Nkx-2A" l16r Nos- I I1-10 Nos-2 "Inca" Ntcp lrebp "Olaf-3 . . . . "Itgb4 . . . . Oias-4" "KcrY' Osf-1 Lhr Pcna Lta4h Pcna-psl Ly-40 Pdi 'Zyam.l" Pea-3 Maria-2 "Pgerep3" "Mashl" "Pgh" "Mash2" Pkmr "Mcp-1" Pray -52 "Mcp-5" Pray-55 "Mel.18" Pray-64 Mg m t "Ppa~' Mmv-21 Ppy M ov-12 Prkar2b Mov-21 'Trpb" Mpmv-31 "Q300" "Msbp- 1 " roe-1 "Mtap-2k" rat-2 Mtv-46 "Rahl" Mtv-47 "Rape" Mtv-48 Rn4.5,v Mtv-49 "Rnl8d'

"Rpa" Rp118 Rps15 Rps24 Rxra R x,rb Rxrg "Scp-2" StuN" Smstr-1 Smstr-2 "Spi-2.2" "Spi.2.Y" "Strs" Taclr T~c.2r Tcfcp2 "Tcf-UBF" "Tea" Thra2 Thrbl Thrb2 "Trfr" ''Tsga'" Utg Vcam-I "Vie" Vip Xmmv-78 Xmv-6 Xmv-56

Chr9

Chr 10

"DgHI4" "D9Haml " DgNdsl DgR til Heft Lv$ Mine Mrav-20 O0'~-rs9

Amh Bsg D lOLedl D l OLed2 D l OLed3 D12S53Eh Fisp12 Mip Xmv-31 Xmv-51 Xmv-54

Rlbpl Tel7p Zfp-36

Ang Cchll ad D14Ehll "D14H41" DI4McCI Gnrh(hpg) SO~-I S~fp-2 Tcra-V15 Tyrp-2

Clu" 77

Adrb-3 Atp4b DSFcrl "DSHII" DSMcCI F~-22 Fit-2 G~-6 KaL3 Lyl-I Pcad

Cntf "D19H42" D19McC1 D19NdM His-2 Rln Top-1

Chr X Cbx-rsl "DXPas?-17" DXNds3 "DXPas?-18" DXOrH "DXPas?-19" DXSmh7 "DXPas?-20" DXSmh9 "DXPas?-21" "DXPas?.1" "DXPas?-22" "DXPas?-2'" DXPas23 "DXPas?.Y' DXPas25 "DXPas?.4" DXS296h "DXPas?-5" Fmr-1 "DXPas?.6'" Htrlc "DXPas?.7" ld~ "DXPas?-8 . . . . Ms6-X" "DXPas?-9" "Npc62" "DXPas?-IO" Rps4x "DXPas?-lt" 'Tfe3" "DXPas?-12" Ube-1 "DXPas?-IY" "DXPas?-14" "DXPas?-15" "DXPas?-16"

Table 2a. Changed locus symbols. Chr New Symbol New Loc~ Name I Cd3z T oell receptor complex Cd3-z chain 1 Fcgr2 Fc low affinity IgG receptor 3 (aFcgR) 1 Ncl nucleolin 1 Fcgr2 Fe epsilon low affinity receptor 1 O&.rsl omithinc deeax'boxylsse-related sequence- 1 1 Rnu3b-psl U3B small nuclear RNA-3 pseudogene 1 2 Emv-13 endogenous ccotropic MuLV-I 3 2 Odc-m2 omithine decarboxylase related sequence-22 2 Rnu3b.ps2 U3B small nuclear RNA pseudogenc 2 3 Fgf.2 fibroblast growth factor-2 3 Odc-rs3 omithine deearboxylase related sequence-3 4 Odc-rM omithine deearboxylase related sequmee-4 4 Rnu3b-ps3 U3B small nuclear RNA pseudogene 3 5 D5Sc25 DNA segment, Chr 5, S Cheng-25 5 Emv-I endogenous ecotropic MuLV-1 transcription factor- 1 5 Tcf-1 6 Odc-r~5 ornithinc deearboxylase related sequence-5 6 7 7 7 7 7 7 7 7 8 8 8 8 9

Rho DTCw18 Emv-ll Emv-23 Odc-rs6 Odn.rs7 Rtbpl Sm'p2a Snrp70 D8Fcrl Emv.2 Emv-26 Gnb-lrsl Odc-rsl4

lO

Gja-2

10 11 11

Rnu3b-ps4 Epb3 Emv.14 Eif4~

12 12 12 12 13 13 13 14 15 15 16 17 17

"Nkx-2.1" Odc-rs8 Rnu3b-ps5 Ctla-3 D13Crc1 Hbvi

Odc-rs9 Cypllb-2 P dgfb Emv-t2 Hsp70 Odc.rsl5

17

o~-3

18

Fech R nu3 b.ps6 Od.c.rsl3 Amel Cdr DXS32 h

19 X X X X X

9 9 9 9 "~ 9 ? ? ?

Sbx BI(R~.2) Csfgmrb DOTu6 DOTu7 DOTu8 DOTul l DOTu12 DOTul3 DOTul5 DOTul7 DOTu31 DOTu44 DOTu46 DOTu51 Eel-2 Eel21

e42-ps] ? ? ?

"Eef2-rsl" E~fla Fert

rhodopsin DNA segment, Chr 7, Case Western- 18 endogenous eeotropie MuLV-11 endogenous ecotropic MuLV-23 omithme deearboxylase rehted sequence-6 omithine deearboxylase related sequence-7 retinaldchyde -binding protein 1 U2 small nuclear ribonucleoprotein polypeptide 2A U1 small nuclear fibonucleoprotein 70kDa polypeptide DNA segment, Chr 8, Frederick Cancer Rea-1 endogenous er MuLV-2 endogenous ecotropic MuLV-26 guanine nucleotide binding protein 1, related sequence 1 omithine decarboxylase~related sequence-14 gap junction membrane channel protein al U3B small nuclear RNA-3 pseudogene 4 erythrocyte membrane protein band 3 endogenous eeotropic MuLV-14 eukaryotic translation initiation factor 4e homolog of Drosophila NK-2 omithhaedeeaxboxylase~Jated sequence-8 U3B small nuclear RNA-3 pseudogene 5 cytotoxie T lymphocyte associated protein-3 DNA segment, Chr 13, Clinical Res Ctr-1 hepatitis B virus trausgenic insertion site omithine deearboxylase related sequence-9 steroid- 11b-hydroxylase (aldc~terone synthase) plaflet-defived growth factor, beta endogenous ecotropic MuLV- 12 heat shock protein 70 kDa omitkine deearboxylase related sequence-15 octarner-binding transcription factor-3 ferrocheistase U3B small nuclear RNA-3 pseudogene 6 omithine decarboxylase related seq-13 amelogenin cerebellar degeneration-related antigen DNA segment, Chr X, human DXS32 Sxxb X-homolog B1 repeats associated with Rnu2 colony st~nulating factor, granulocyte macrophage receptor, 15chain DNA segment, Tubingen-6 DNA segment, Tubingen-7 DNA segment, Tubingun-8 DNA segment, Tubingen-11 DNA segment, Tubingen-12 DNA segment, Tubingen-13 DNA segment, Tubingen- 15 DNA segment, Tubmgen-17 DNA segment, Tubingen-31 DNA segment, Tubingen-44 DNA Segment, Tubingen-46 DNA segment, Tublngen-51 eukaryotie translation elongation factor 2 repetitive EeY2 like sequences elongation Wanslation elongation factor-2 pseudogene 1 gene expressed preferentially in MEL cells "Eel2 related" eukaryotic trauslation initiation factor 1 a (Tu) fe~ (fms/fl~ related) protein kina:~e, testis specific

Old Symbol

Old I z ~ Nam~

T3-z chain lyrnphoeyte antigen-17 DNA segment, Chr 1, Naffield Dept Surgery-28 Ly47 lymphoeylr antigen-17 Ode.1 omithine deearboxylase-related sequence-1 Rnu3b-rsl U3B small nuclear RNA-3 related sequence 1 AKR leukemia virus inducer-3 Akv-3 o~nithine deearboxylase related sequence-2 Odc-2 Rnu3b.rs2 U3B small nuclear RNA related sequence 2 fibroblast growth fact~, basic Fe# omithine decarboxylase related sequence-3 Ode-3 omithine decarboxylase rehted sequence-4 O&-4 Rnu3b-rs3 U3B small nuclear RNA related sequence 3 D5Mit25 DNA segment, Chr 5, MIT-25 Cv.1 BALB/c virus inducibility-1 hepatic nuclear factor-1 Hnf-1 omlthir~e decarboxylase rehted sequence-5 Odc-5 opsin "Ops" D7Tml8 DNA segment, Chr 7, Terry Magnuson-18 Akv-I AKR leukemia virus indueex-1 C58v-4 C58 endogenous ecotropic virus-4 Ode-6 omithine decarboxylase ~ateat sequence-6 Ode-7 omithlne decarboxylase related sequence-7 "Cralbp " cellular retinaldchyde binding protein Srnp2a U2 small ribonucleoprotein polypepfide 2A S rnp 7 0 U2 small fibonucleoprotein polypeptide 70kDa polypeptide ecotrepic proviral integration site-8 Psx-8 By-1 C57BL/10 endogenous ecotropic virus C58v-1 C58 endogenous eeotropie virus-1 Gnb-4, Gnb-3 guanine nucleotide binding protein-M, -b3 0dc-14 ornithine deearboxyla s~rela t.ed sequence~14 "Cnx43" connexin43 (gap junction protein) Rnu3b-rs4 U3B small nuclear RNA-3 related sequence 4 Empb3 e~hrocyte membrane protein band 3 Akv-4 AKR leukemia virus inducer-4 translation initiation factor 4e (e/F-4e) thyroid nuclear factor-i 'Ttf.l" Ode-8 c~rfithine deearboxylase related sequenco-g Rnu3b-rs5 U3B small nuclear RNA-3 related sequence 5 Hanukah faet~ Hy "P198r" P198 related sequence D13Pas2 DNA segment, Chr 13, Pasteur Inst-2 O&-9 omithine dccarboxylase related ~lumco-9 Cypl 1b ~*roid- 1lb-hydroxylasr Sis simian sarcoma oneoSene AKR leukemia virus inducer-2 Akv-2 Hsp68 heat shock protein 68 kDa Odc-15 omithine decarboxylase related sequence-15 0r octamer-binding transcription factor-4 fe~x~chelatase "Fcl" Rmdb-ps6 U3B small nuclear RNA-3 related sequence-6 0dc-13 omithine deearboxylase related seq-13 amelogenin Amg ~ a r degmca-ation-related antigen 34 "C&M" DX7Pas DNA segment, C ~ X, Pasteur Institute-7 "Alsg" ts A1S9 defective DNA replica6on gene "Rnu2.B1" B1 repeats assoc with Rnu2 intcfleukin-5 receptorbeta "llSrb'" D I 7Tu6 DNA segment, Chr 17, Tubingen-6 DNA segment, Chr 17, Tubingen-7 D 17Tu7 D17Tu8 DNA segment, Chr 17, Tubingen-8 DNA segment, Chr 17, Tubingen-11 D17Tu11 D17TM 2 DNA segment, Chr 17, Tubingen-12 D17Tu13 DNA segment, Chr 17, Tubingen-13 D17TM5 DNA segment, Chr 17, Tubingen-15 DI7TM7 DNA segmem, Chr 17, Tubingen-17 DNA segment, Chr 17, Tubingen-31 D17Tu31 D17Tu44 DNA segment, Chr 17, Tubingen-44 D I 7Tu46 DNA segment, Chr 17, Tubingen-46 D17Tu51 DNA segment, Chr 17, Tubingen-51 elongation factor 2 Ef-2 repetitiveEl2 like sequences ~pt E f2-ps elongation factor-2I~dogene gene expressed preferentiallyin MEL cells"El'2related" "Ef2-rsl" elongation fsctor la [Tu) E#a Fer For protein (kinase), testis specific T3z Ly-17 D INds28

Continued on next page

J.T. Eppig: Clones and Probes

303

Table 2a. Continued.

Chr New Svrnbol NeWLocusNamo ? ? ? ? ? ? 7 7 ? ? ? ? ? ? ? ? ?

ll3rb Ipp Kcrl-1 Kcal.1 Kea2-1 Kcr2-1 Ly-M Macs Mark Oxt Rpl7.psl Spi-2rsl Tcfpul Tpm-2 "Tpm-5" Trapla Vsp

interleukin-3 receptor, 13chain IAP promoted plaosntal gene K+ channel, delayed roetifier, subtype 1, gene 1 K+ channel, A current, subtype 1, gene 1 K+ channel A current, subtype 2, gene 1 K+ channel, delayed roetifier, subtype 2, gene 1 lymphocyte antigen-51 myritoylated alanine-fich Ckinase substrate midkine oxytocin Ribosomal protein L7 pseudogene-1 se.6neprotease inkibitor-2 related sequmos-1 transcription factor PU.1 tropomyosin-2 beta [isoform 2] tropomyosln-5 tumor rejection antigen PlA vasoprc~sin

Old Symbol '7/3r" Mipp Shah Shak Shal Shaw

Bt~1/6c3 Marcks "Mek" Oxy Surf-3ps "Spi-21" "Tfpu.l " 'Trop-2" '7'rop-5" "Tra-PI A"

vp

Old Loc~ Name interleukin-3 receptor mouse IAP promoted placental gene mouse brain K+ channel 0mmolog Dros. Shah) mouse brain K+ channel (homolg Dros. Shak) mouse brain K+ channel 0mmolog Dros, ShaO mouse brain K+ channel (homolog Dro. Shaw) BP-1/6C3 antigen glyeoprotein myritoylaled alanJne-rieh Ckinase su'~-trate midge.stationembryo and kidney gme oxymcin surfeit gene-3 pseudogene sea'ineprotcase inhibitor-2 like (ountrapsin-like) transcription factor PU.1 isoform 2 tropomyosin 5 minor rejection antlgcaaP1A vasopressin

Table 2b. Changed gene location assignment. Chr I 1 1 2 2 2 3 3 3 3 4 6

Svmbd Ncl Pray-45 "St2" Gsn Mpmv-3 Rag-1 Bglap Cf-3 Mpmv-lO Glut-2 Pax-7 Ret

6 6

Rho Sftp-3

7

Fur

7

Gas-2

8

Ca@

8

18 18 19 ?

Pmv-lO Penk Gja-1 Pfkl Pray-8 Pmv.13 Xmv.31 Glut-4 Eif4e Ctla-3 Gas.l Tkrb Nfm Np-I Acr Cypllb-2 Hmgi Rnu14 Fech Pray.20 Pax-2 DOTu6

?

DOTu7

? ? ? 7 ? ?

DOTu8 DOTull DOTul2 DOTu.13 DOTu.15 DOTul7 DOTu31 DOTu44 DOTw46 DOTuSI Lmyc-2 Rnula-ps

9 10 10 10 10 10 11 12 13 13 13 14 14 15 15 17

17

7 7

7 7 ?

?

Lcm~ N~ne nucleolin polytropic murine viras-45 signal transduetion-2 gelsolin modified polytropic routine leukemia vlms-3 recombination activating gene-1 bone g-carboxyglutamate prot (ostcocalcin) eoaguIatinn factor ITl modified polytxopic routine leukemia vlrus- 10 glucos~ :ransporter prcaein-2, liver paired box homeotic gene-7 Ret proto-oncogene flaodops'in

pulmonary suffactam apoprotein-3 fufin, membrane assocated recctxor protdn growth ~ ~ed,fie gene-2 placmud cadhca~rl poly~opic murine virus-8 preprocnkcphalin gap junction membrane channel protein al phosphofructokinase, livr polytropie routine virus-8 polytropic murine virus-I 3 xenotropic murine leukeraia virus-31 glucose t r a n ~ pror -4, muscle eukaryotie translation initiation factor 4e cytotoxie T lymphocyte associated p~tein-3 growth a~e.st specificgme-1 tyrosw e kinase re.cq~or B pmtooneogenc neurofilament, medium polypepddes nueleosidr phosphorylasr prept~oros~n ~ i d - 1 lb-hydroxylase high mobility group protein I UI4 small nuclearRNA (c~coded in hsc70) fcarocbehtasr polytropic murine virus-20 paired box homeotic ge~e-2 DNA segment, Tubingen-6 DNA segment, Tubingen-7 DNA segment, Tubhagen-8 DNA segment, Tubingen-i 1 DNA segment, Tubingen-I 2 DNA segment, Tubingen-13 DNA segment, Tublngen-15 DNA segment, Tubingen-17 DNA segment, Tubingeaa-31 DNA segment, Tubingen-44 DNA aegment, Tubingen-46 DNA segment, Tubingen-51 lung carcinoma myc-rdated oncogene-2 UI small nuclearRNA-la psuedo

Old 10cation~ t (formerlyunknown) (fomaerlyChr 15) (formerlyunknown) (formerlyunknown) (formerly unknown) (formerly unknown) (formerlyunknown) (formerlyunknown) (formerlyunknown) (formerlyunknown) (formerlyunknown) (formerlyunknown) (fonnerly unknown, Ops) (formerly unknown) (formerlyunknown) (formerly unknown) (formerly unknown) (formerlyunknown) (formerlyunknown) (formerlyunknown, "C~43") (formerlyunknown) (formerlyunknown) (formerlyunknown) (formerly unknown) (formerly unknown) (formerly unknow.L lf4e) (formerly unknown, Hf) (formerly Chr 12) (formerly unknown) (formerly unknown) (formerly listed under Chr 9 and 14) (formerly unknown) (formea:lyunknown, Cypllb) (formezlyunknown) (formerly tmknown) (formerly unknown, "Fcl") (formerly unknown) (formerlyChr 7) (formerlyChr 17) (formed, Chr 17) (fomaefl ~Otr 17) (fomae~ , Clar 17) (forme~ , Oar 17) (formen:l:,~ 17) (formed r Clir 17) (formed rOar 17) (fonn~cl rChr 17) (fomamt : Oar 17) (formed r On" 17) (formed t On" 17) (formed r Otr 12) (formedy Oar 11)

1

2

Mns-I e

3

Mns-2 e

U

Mpmv-42

~

Pmv-45

i/er~ ["--

Mns-3 e

I Vim ~ / O0.3.rs2 I / I sp,~.2 [,///Pax-8 I/I/SurflRpt7 [[/'/Jgf-1

I I lllr-lllllr-2 I II Amh-rsSlDIFcrl I I I/Co~-s

V I I abI

Ap2 V_/ Car-1 [~- Car-2 I...~ O~-rs3 [.~" Car-3 i "n-7 - - Mpmv-20 i EW-1

D3L~h2

V/[/]1 Cryb(=Len-2 )/Mylf

[iii//Co~o-s

l//Ill/Fa-llNcl DI ~t~ - - l lllll/s~dr~-~ ,Emv-20/Vil t Des/lnha t Pax-3 Msl-3-2-P2 "--- t AcrdlAcrglAkp-3 I Bcl-21DILubl Msl-2-4-P2 , Snrpla-rsl , Mpmv-34 ,Mtv-39 , Emv-16/Emv-17 , Rnul-psl ' En-1 , Al~o-41C4bp Ms2-2-16-P1 I Mpmv-6 Ms2-2-17-P2 "1" , Ren-llRea-2/lap(Ren-2) MslO-2-6-P2 .I Mpmv-16/Mpm~-37 MslO-2-7-P1 i " ----"Kras-11Mpmv-32 - - Myog Ncf-21Rnul-1/Xmv.21 " " Odc-rsl - - Ly-5 D ILehllRpr-1 Cfh .06r3.rsl Ms4-1-11-P2 SsalXmmv-9 x Otf-1 " Xmv-41 "Lamb2 ' Abll/Xmv-32 ' Xmmv-36 " At-31Bxv-I ' AdprplMpp ' AtplbllCd3z/Cd3n ' Cf-5/ElamlGrmp/Lnhr ' Gsh-4 ' Apoa-21Bcm-I ' Fcrg31Fcrg2 ' A~la2lCrpISap DIPasl-' FcelalFcelglNscI lfi20111f'~O211fi203/lfi204 Mmv-14/Mtv-7 Spna-11Mtv-27 MPmv-291Pmv.24 Mpmv-25 Eph-llPmv-44 AI~o-IIDIBM49 HlxlMintblTgfb-2 Cd341Cr-21Crry Mprav-22/Prnv.21 Mpmv-35

Msl I-I-I-P1/" [ /1 ~ g t : 0 ]/A Gad-1 Ma l-2 4-e l \ Msll-2-6-e2 / ~ff l/ His-1 I/ Ih Neb Ms11-1-3-P2 ~s D2Lehl - , Pray-7 , Hox-4 , Pax-6 rAcra rEvx-I ' Ly-24 ' Sfpi-I ,Mpmv-14 DZHgul \ , Xmv-48 Ms3-3-4.PI \ \ ' Cf-2 DI 1Sl6h ~ t ' Cas-I DllS408h ~ ' Rag-ltRag-2 DllS41 lh, ' Fshb DIIS412h" 'Sty D2Mitl " ~ Wt-I Ms5-1-1-P2 / ~ / Actc-1 Ms5-2-8-P2 "// i Thbs-I Ms5-2-9-P1/// Ms5-3-4-P2 "/. D2Leh2 ' / 2 "B2m Ms3-1~6-P1 " / ~'' Pol-23 P~a Ms3 -2-15-P1 - Msl-I-3-P2 X I'GIvr-I MsI-1-5-PI ~, t'll-lalll'lb Msl-2-17-P2 i ' Mpmv-28 MsI-2-I8-P2 , I;Prn-p Msl-2-10-PI " 'Bmp2a Msl-3-3-P2 " Hdc Msl-3-7-P1 f ~ \ Ms2-1-4-P2 I/1//// 'Paz-l{=un) Ms2-3-2-P2 "/, Emv-13 Hck-I Pygb Ms2.3-6-PI '/ /// Ms3-3-6-P2 " / Odc-rs2 Ms3-3-7-P1 '~r ,asp Ms6-1-6-P2 " / a Ms6-1-7-PI Erav-15 Xmv-lO Rpn-2 Src Ada SW.1 Pray-33 Pck-1 ~Kras-3 \ Gnas

t:p-2 lnhbb Mmv-5 Mmv-9 So Wnt-6

Fg[-2 O"b"rs3

- - II-2

Mtv-14

Calb - - Tsha

/ Ggtb . . t Mtv-17 i Pray-30 / Xnv'nv.8 M~8-3-12-P1 --MsS-3-12-P1 ,Mul,_i rLv ~b iRrm2-psl rOrm-1 r Orm-2 r Orm-3 , I/a , l/b Jim ' Odc-rs4 9

Tpl-2 Gba Pray-38 Rnulb-1 Rnulb-3 Acrb-2 Cap-2 Fgg Xmmv-22 Cacy Ly-38 Pmv-28 Xmmv-65 r Nras MsI1-2-I-P2 ~ ,Calll Msll-3-3-P1 ~ , Carl O3YfiI I " / C:fm(=o; ~-37 Ms2-3-12-P1 ~ ~ Pray-39 Ms6-1-2-P2 "-~ "Ampd-I Ms6.2-1-P1 - ' A~lal ~' Ng[b Tshb ~Amy-I Amy.2 I Cf-3 ~Emw27 Ampd-2 kFabpi t Lef-I l Adh-lps ~Gl~-I ' Egf 100"3"rs4 ' Adh-I ' Pray-26 "" Mpmv-9

Ms6-2-7-PI ~ Ms6-2-6-P2 ~ Ms6.3-7-P2 :

I D3H44 D3McC1

DIH18 DIH37 DIH46 D1H49 D1Lub2 D2S3h

al,,,-2

~

- - Hap86-ps2

tcra4

Acp-2

--

D3Lehl -- ~

[////,

D2H43 D2H28 D2H16 D2McC1 D2Mit2

/ Hck-2 ~ - Lyn

~" Fkn-3

Us8-3-2-P2 "-1/I/~pmv-~

~1111/Cd28/Ctla-4

i

Mns-4

| / I ~ lira

Rnu3b-psl Mtap4

4

Acts Ank-2 Arm Bglap Fth-rsl Hist2 Mov-lO Mpmv-lO Oua.1 Pgk-lps3

Ms6hm - -

, Prnv-23 , Mmv-15 ' Mtv-13 D4Rp1 \ ' Pray-19 Ms2.3-19-P2 , 1 / C,lut-1 Mxg-3-6-P1, / Lmyc-I Ms4-3-5-P1 ' / Pray47 MsI5.1 ' "Pray-51 Ms1.2-11-P2' I Mpmv-36 Msl-3-9-P2 ' - - Ck-1 Ms2,3-1 O-P2/-~[~ Hck-3 Ms2-2-9-P2 f ' ~ ' l_r MsS-2-12-P2 " D4Smh6b ~ ' Mpmy-19 ' Fabph-I Ms5-3-1-P2 '\~ "" Xmmv-23 MsS-3-2-P1' ' Akp-2 Ms6-3-1-P2" ~ - . , l~sr Ms9.2-7-P2 \ \Plc Ms9.3.10-P2 " ~ \ n,;d Msg-3-9-P1 "'/r ~-. "J "," $ -- ._ M 9-2-5-P2 "1111\%\ U ~"-M,3-3-1l-n /11 [\\%~ ' ~ M,3.2..-,2 Ms6-2

1

M,o-za-~

7#

X,m,-44

I I I Itl rmv-z-~

I \~ x,,,.,.-62 I \II' C-.b4

D4H30 D4H33 D4Haml D4McCI D4McC2 D4Nds3 D4Rp18

Apnh Cycb Cyp4a Fabph-4 Hrs-1 Hrs-2 Pgk-lps4 Rmrpr gnu3b-ps3 Tag-Rb War..4 Xpa

nan/ Bmi-I Bmyc Chsb Dlx-I Gsn Hap84-2 ll2ra Kin Nk~-22 Phpp-2 Rnu3b-ps2 $8 Ss,t,.l

Fig. 1. M a p of loci for w h i c h probes/clones are listed in Table 3. Loci m a y have multiple probes listed. Probes for which gene location is u n k n o w n or w h i c h identify s e q u e n c e s on multiple chromos o m e s are not included on this map. F o r each c h r o m o s o m e , anony m o u s D N A s e g m e n t s ( " D " loci) and microsatellite ( " M s " ) sequences have b e e n placed to the left and n a m e d genes to the right.

J.T. Eppig: Clones and Probes

305

5

8

7

6

/Emv-ll/Pmv-4 ~ / Pkcc i'll O0~.2/Pmv-29 ///Apoe/AqMa3 ///CealCknm .

Mns-5

-

D / /

Ms5-3-3 -P2 Ms4-1-3-P2 \ Ms4-1-7-P1 Ms4-2-11-P2 Ms4-3-12.P2

Gsh-3 Pgy-llPgy-21Pgy-3 Pmv.-40 / En-2 ~ Mpmv-23 ~

Met Wnt-2

Xmv-17

> Xmv.45 \ II-6 "~ Xm~-34 .~ Hox-7 \ Mpmv-13

-

:Tcrb

Ms3-1-9-P1 D5Sc25, Ms6-1-4-PI , Ms6-1-5-P2 " Ms6-2-5-P2 -~ Ms6.2-9-P1 "/ Ms6-3-2-P1//I Ms6.3-4-P2 ' / Ms7.3-8-PI

~ Xmv-38 ~ " Dao-1 ' Cncg Gsh-1 Kit(=W) / Pdg#a " Pmv-l l ./Csna

Cpa

Ms3-2.-8-P1 Ms3-3-8-P1

: Try-1 / Mtv-29 :Npy :Hox.1 :ho / Cb1-1 M#-~OZ

: Oq'3-rs5 Xmm v-2 7 9

Mtv-8

"Fabpl "Igk

"Ly-2 ~ Ly-3 Mtv-23 RnTs-6 , [email protected]

D5LeM

: Re:

Mns-7 \ D7Smh57",, D19S51h " D19S19hlErcc-2 \ Ms4-2-20-P2 ' Ms2-1-3-P2 ' ~ Tpi-3/Xrcc-1 Ms2-2-14-P1 ' ~ Cyp2a41Cyp2aS/Cyp2b Ms2-2-15-P2 " "" Pmv-181RiplTgpo-I MsS-2-10-P2 "~. \ Ryr D19FllSlh / "Bcl-3 D7Ag2 . . t "Pray-15

Ms4-2-17-P1 Ms4-14-PI -~ Ms5-1-5-PI ~ Ms5-1-6-P2 ~ Ms5.2-11-PI ~ /

z~.z6

'Gpi-I/Mag 'CebpID7Rp2/BI(DTRp2) 'Xmmv-31 Odd-m6

M,S-m.n

"~ Mpmv-llMtv-1 Gabrb-3/Xmv-33 Ft$ DTRn2 \ D7CwI8 ~

--

~ Lyz.1 D8Pas2 "~. ~ Msl-2-9-PI ~, [ / Ms2-2-8-P1 ~ Ms8-3-11-P2 / ~ I

Pcad

/ Omp ~ Rt..6 Calc/D7Smh5 3 \ PtMRpt-1 - - Hbb ~ Odc-rs7

- - Zp-2

D7Smh751Ly-15 "

Pkcb --

ll4r

rpi4 " 1m..41 ~" Odc-rs5

- - Cyp2el

D6Lehl

~ Ctrb

iLo

Emv-26 ~ _ Xramv-2 9 Mprnv-21 DSPasl - - ~,~ Erav-29 r~,~" Gnb-lrsl Emv-2 / Aprt , ~ Agt lap(Agt)

/ H19 -.-'Th ~ Fis-I Hsrf.1/Du-2

D5P~I

--

Mtv.35 DSFcrl DSHI I DSMcCII

DSGotl DSH6 DSH13 D5H17

"

Actb Asl F~f-5 Flk.1 Flt-3

Actg

Bra~-2 Clc-1 Fth-rs2 Gnb-3 Hmgi-rs2 Ins-1

Ust~e Gc Pal-1 Sri Udpgt-3

Ucp Es-I Es-22 Mr-1 ~ Mr-2 9 Mov-34 / B1 (Urn)

/ ca,tp

D7Was12

- erp

cph.l

=

I

D6Mud D6NdM D6Nds6

/, Act-6 '/Xmv-12 / Crry-ps/Mel Jund

\~ Myo~-1

D7Smh71/p / \ ~ Saa D7Nicl - - N Gas-2 ~.,~Snrp2a \ ~ Hras-IIlgfl r

MsS-2-7-P1 ~ MslO-1.-6-P1 D7Smh59 ~

/ lapp / Ly-49 Mtv-34

D8Fcrl -

MsS-2-11.P2 //~//~ KallLhbIEgl~ Ms8-3-10-PI/ff ~ Nrg[as~/N~n~TgTOlXm,.30 Ms8-3-13.P2 ' / ,\~ Ldh-1:1"ph

D7Orl - "Pal-20 " Spp-1 ~' Pdeb(=rd) ' mv-28 Bmp-3 ~' Cyp3

'

Pcp-2 ?'- Polb lttrr I" Gas-6 / Ank.l / Plat Atp4b Xmv-26 ~ Defcr Fit-2 Gr-1 Tea

Mns-8 -

Pim-lrsl Por Pthlh

epn-I Syb-1 Wnt-SB Wnt-7A

D7H8 D7Hdd .7 D7Hd3U D7McCI D7McC2 D7RT305 D7RT336B D7RT453B D7Tm3a

Ass-psl B~ Calm Cd43 C'yp2b9 Cyp2bl 0 Cyp2f

Fah Fosb Fur G~p Hrr

1#2 lns-2 lnt-40 LIMd-6(Hbb) L1Md-9(Hbb) Ldh.3

Mylpf Oat Rlbpl

epsl6 Rrml Rrm2.ps2 Tapa-1 Tel7p

rg74 Xmmv-15

Adrb-3 Fabph-2 Gc-rsl Kal-3 Mtv-21 OX-I Tg.Myc

306

J.T. Eppig: Clones and Probes

10

9 ~ Pvs Mns-9 "q

11

IL

~ Ly.47(=Icam-1)

Mns-ll ( DllWasTO - -

-- Xmmv-67 E~or

/ Act-2 . . I Emv-25 J " Estr - Mpmv-5

,i-4 I Call h Mmv-20 I poa-4 Xrnv-16 / Cbl-2 / T3d/T3elT3g 9 Thy-llUps

~

' G~ta

Msl 0-2-1 -P2 . MslO-2-2-P1 -

9Crbp Ms2-3-3-P1 \ Ms4.2-~-~1 . ~ Ms4.3-IO-PI --~ Msl.2.5-P1//// - - T q Ms2-2.6-P2 / MsI1-1-5.P2 f " Gnai.2 Ms3-1.3.P1 \ Gnat.1 Ms3-1-4-P2 \ \ Ms3.2-9-Pt gs3-2-10-P2 -~/ Ms3-3-13-P1/// - - B g l Ms3-3-14-P2 :/~ Ms4-1-8.P2 +// MM.1-9.P1

Adra-I _ , . ~Uat$-J , . '

Tel. 6

rpi.7 " " Ros-1

DlOCosl - -

/

/ tra~ra-1 . ' usjgmlSparc

t~r~f Py~

/ Pray.-8 J'dl

"Cyplla

DgAg3

Ahi-I Mpmv-12

uy~ ~

" Cypl9 Xmm v-2 ' Cypl allCypl a2 N cartl Acra-5 Xmv-15 ' A cra-3 ' Mpmv.27

Ms3-2-20-PI Ms3-2-21-P2 IMSI Oh Ms6-1-3-Pl MslO-I-IO-PI

Xmv-54

//eh

./Xmv-31 / " Cdc.2 a l~cr Cot6a-I DIOPasl - ~ Col6a-2 "SlOOb DJ OLedl \ "" Amh D10Led2 ~\~ ""- Tra-1 D10Led3 ~/ - - Pak DlOPas2 ~ le,f-1 rs.~

- i llg

MyZc

D3FISS2h D3S92h D3S93h DOH14 DgHaml D9Ndsl

Acrb-4

cp H:

Lq Lvs 0r

Rbp-5

Mdm-1

Ass-ps2 8sS Cdl8 Egr-2 FispJ2 Gad-lps Gja-1 Hal Hb58 Mdm-2 Mip

eyrz

Pray-13 Prim1

R~uSb-v~4

Emv-14 t Shbg t Asgr-llAsgr.2 Atplb2/Dl lLehl ~ Glut-41Rpo2-1 Trp531Zfp-3 : E@-I : Mov-g/Mpmv-4 / Evi-2 9 Zfp-2 / Acrb/Mpmv-2 Tca-31Xmv-42 Hsp86-ps l -- nipla/MipJb Mmv-16

Cola-I/Neaer Hox-2/lap(Hox-2.4)

- - Xmv-51

DI2SS3Eh

i

'Si~ie

MeJ(=St)

- -

' Mga'-111-~/I~'Ut'3) M,7-1-1-P2///]I[--Ltrm-I / "" fl'" " Ms7-2-11-P2 I/if~ 1l"4 It-3 1/// / 7 Ms7-3-10-P2 ~ Pray-3 ' Myhs Myhs.e/Myhs-f nyhs-p D12Nyud ~st I

9 Mrav4 7/Mpo 9 Xmv-20 9 Xmmv.77

- - Cck --

Pray-2

- -

- - Pray-22 / Erbb / Mpmv-18 I" Gl,,ts i Pmv-46/Pmv-58 - - Re1 ""-" Emv-30 ~ Ck-5 HbaIHba-x

~ Odr -- Penk

/ Mtv-30 Mns-12, ~ / P o m c - J O12Lehl , F ' / Apob D12Nyu2 , ~ Pray-37 D12Nyu.5 ~ ~ _ Rnr12 Dl2Nyu7 ~ [~'x"Synd D12Nyu10, l \ ~ Nmyc.l Ms7-3-5-PI ~ ~ Odc Ms7-2-7-PJ ~ [ \ " Pol-7 DI2Mcgl ~ V~" Mmv-18 Ms1-2-14-P2 ~ ~ " Lambl-1 Ms1-3-8-P2 Ms2-2-12-P2, Ms2-1-6-P1 " Ms2-1-7-P2 " I Ms2-2-13-P1 "~,~1 // Ms2-3-11-Pl/~ Rnula-2 I / /tt--j ~ Eif4e Ms2.3-24-P2////I .M~Z-.~-I-I*Z ...... ///:~ -

Mns-lO -'t ~ ' - Dmdl

Ms7-1-8-P2 - Ms7-2-15-P2 -DgLeM

12

DllH38 DllHaml DIlMcCI DllNds2

Krt-llRttula-1 i CsfglXmv-47 Erba/Erbb-2 Cnp-1/Emv-28 LGfap/Xmv-49 Epb3 i Mpmv-8/ Myla 'Int.4 Pmv-56 ' Pkca 'Gh Mtv-3 Gaa Tk-1 \ Mpmv-15 Cabm Hragi.rsl Krt-lps

Li/ Mov-13

N:h

P deg Rata Rnu3b-I Rnu3b-2 Rnu3b.3 R nu.3b-4 Syb-2 TgTtr-2

Thbp Writ-3

Wnt-3A

7/

" ' - Spnb-1 - - Fv-4 D12Nyu3 - - ~ Fos ~ Tgfb-3 D12Nyu4 - -

D12Rp54 - -

-/ ~ --

Mtv-9 Amh-rs4 Pray.27 Xmmv-21

/ /

Aat

~ Ms4-3-15-P2 ~ Ms5-2-13-P2 ~

Tshr

spi.1 Spi-2

..--"Hsp86-1 ~ Mpmv-24

~ Dl2Nyu9 ~ ~ Ms7-2-2-P1 . ~ ~ Ms7-3-1-P1 / ~ DI2NI : -MsS-2-3-P2 ~ ~ MsS-3-5-P2 /

iv Xramv-50 Ct-3 Ata CHp lgh-C Igh-V Odc-rs8

Hsp84-3 lfi12 Mylf.ps Nlar-2.l Rnu3b-ps5 Rrm2

Ts.ct+ X, unv-25

~.-~ ~ ~ ,

~

~

~

I

~'~ ~

~

~

~X//--'/" I II

, , ,~ ,~ ~ ,~ ,~ ,~

,

/

I\

5? u:

I

/1 A A

~_~,~'~'~.~

/A ~.

/X

\

~5

-.

/~I

II / A ~

I~

~

,~.~.-~ ~ ~ ~:a ~:

/////~X..

/A \ /,.'IA \ /~

I

I

A

w

A

I I ~e'

~ ~ , ~ . . . . . . . . .

A 11"

c~

g

,

"M krl

::r'

K:b K::~, . ~ . ,

\

f

'

~

I I

_~,~

to~

A

I

c~

.~.~ ,~

I

"" ~ " . . % l / / / J "

,

~'....,.,~

/r

8,~

1

e.,,P.,~.O.

,.t. ~ .1~ ~

A I /t/

IAI

f

I

w

A\\'l 'm'

\

~ i~ ~ ' , ~ "" ~ ~ ~ ~ , ~

//}ll

I

r ~ , ,~.,:..A,,.~", ,.%~,~"~

I/J'~ /

..~ ~ ' ~ ' ~ . ~ ~ , ~

~'~'''~"

f \~1//./~'~

~r~r,,~,,.

I~

,

,o~.~,.~'~"~"~

~'.-.,-.

/lt

~

\

',,O

OO

---3

db

J.T. Eppig: Clones and Probes

X

309

Y

DXWasTO\ ~ / Cybb

M~-X ~

6f-I

DXPas22 \ ' ~ Otc(=spD DXS32h \ \ ~ MaoalMaob DXSmh151DXSmM41 ~X]~--- Pfc DXPasglDXWasl07 \ 1 ~ Syn-1 DXWa~68\ \ L \ Timp DXPas31DXSmhl O\ \ ~ Araf DXPaM \ NI \ Xlr-1 DXBayl/DXBay31DXBaYSDXPas5~k\k~

/ Blon-1 / / ttya S,y

- "7gy-2

Dxs,,aa22 \\,1 DXSmh661DXSmh67 \ \~1 DXSmhI721DXSmh191 \\ ~ DXS,aet~ \\\ l OXCrc'slll \\~I DXSmh361DXSmh59 \ \ ~ DXSrah91 \ \ q / Hprt oxsl44eh \ ~ / x~-z oxs,,aass \ \ V / cf-o OXBaySIOXBayTIDJ~Bay9\ \x~._.- Mcf-2 DXS254EMDXS296h \\ ~1 / Cdr oxs,~a3/oxs,,an4 ~\\ I//Pray..6 oxB~2/ox~

\\\\

y l/V,~-I

oxs25zeh/oxe~s2t \\\\\VI/ c,6ea DXSmh7IDXSmh9 \\\\~[.// Gabra-3 DXCrcI401DXCrc190 \~\~l'/" R~e DXeo.,8 \\YLf cf-8 DXPoM31DXPasI4 ~ , ~

J~cam

DXCrc571DXCrc202~ , DXCrc281DXWas31 DXCrc131 DXCrc169 /if o~t~ay4 ///// DXCrc941DXCrc171 '/// ~ D XSmM 2 0 "//~ DXCrclWZIDXCrc187"/~ o xs,,~44 7#! DXCrcl31DXCrc318 'fill DXPasl9 '1[// DXPas23 I/lit DXCrc1121DXCrc323 I//~ DXCrc471DXCrc98 '///~ - DXPas2 '////~ DXPas25 '///~ DXCrc's[2] 'I/if/ / DXPas20 '[/[[~ o xs,,a43 'Ill\ DXPasI 5 '[lift DXPaslO l[[[ DXPasll 7// DXPaM8 "if~ DXPasI ']/ DXSmh225 'ill OXCtc's[31 7 DXPaM2

Ar(=Tfm) Bmp2b-2 Lmdx(=Dmd) 9Odc-rsl3

cg-1 phta

Ags Cbx-rsl Amel Glra2

Xmv-40

YB]0

- - Mov-15

DXCrc'a[41 D)OVds3 DXOrU

DXPasl7 DXSmhl4 DXSmhg3 DXSmMI7 DX&nh129 DXUcsfl DXJpn"a[l I

Ms6-\

Mov-15 Mtv-31 Mtv-42 Murvy Pray-34 Sxr Tg2736 Ube.2 Ube-3 Xlrl Xmv-7 Xmv-11

Alas-2 BIo'n-2 Blurt-3 Gjb-1 Htrlc Mtv-28 O0'-3-rs8 Pdha-1 Pmv-I Pola

Syp Tfe3 Ube-I Xist

Xlr-rs

Fig. 1. X Chr: There are groups of linking library clones that have been localized to regions of the X Chr. These groups are designated on the map as DXCrc's[1], DXCrc's[2], and DXCrc's[3] and represent the following loci. DXCrc's[1] are located in the centromere-T16H breakpoint region and include DXCrc14, DXCrcl6, DXCrc21, DXCrc22, DXCrc24, DXCrc25, DXCrc32, DXCrc40 DXCrc42, DXCrc43 DXCrc49, DXCrc50, DXCrc53 DXCrc63, DXCrc73 DXCrc95, DXCrcl01, D X C r c l 0 3 DXCrcl04, DXCrc117 DXCrc120, DXCrc128, DXCrc138 DXCrc142, DXCrc149 DXCrc153, DXCrc170, DXCrc172 DXCrc173, DXCrc174 DXCrc192, DXCrc194, DXCrc306 DXCrc314, DXCrc316 and DXCrc366. DXCrc's[2] are located in the T14RI-T6RI b r e a k p o i n t region and i n c l u d e D X C r c 2 3 , D X C r c 4 8 , DXCrc51, DXCrc146, DXCrc162, DXCrcl80, and DXCrc201. DXCrc's[3] are located in the T6Rl-telomere region and include DXCrcl5, DXCrc99, DXCrc134, DXCrc139, DXCrc157, DXCrc159, DXCrc181, DXCrc204, DXCrc309, and DXCrc311. Three additional linking clones not included in these groups are DXCrc301, located distal to G28, and DXCrc310 and DXCrc315, located distal to DXSmh225.

J.T. Eppig: Clones and Probes

310 Table 3. List of mouse DNA clones and probes. Ow $yn'~a

1

Abll

Loam N a m e

Abelson related gene

1

Acrd

acetylcholinereceptor 5

1

Acrg

acetylcholine receptor 7

1

Adprp

poly (ADP-ribose) polymerase (3' end) (5' end)

1

Akp- 1

alkaline phosphatase-1, liver, bone, kidney, Mn requiring

1

Akp-3

alkaline phosphatase-3, intestine, not Mn requiring

1

Akp-4

alkaline phosphatase-4 Akp (placental)

1 1

Amh-rsl Apoa-2

anti-Mullerian hormone related seq-1 apolipopretein A-II

1

At-3

anti-thrombin-3

1

Atpla2

ATPase, Na+K +, a2 polypeptide

1

Atplbl

ATPase, Na+K +, 61 polypeptide

1

Bcl-2

B-cell leukemia/lymphoma-2

1

Bern-1

B cell membrane protein 1

Probeb

[HI ABLL cDNA [H] pargl " p6H

RFLV c Contactd

Kruh Seldin co:GD Kruh co:Heidmann Crowder k46, Z53, ~ 8 , ).60, X61 LaPolla T18 + co:Heidmann + Mock " Buonanno pAcrg + co:JP Merlie " + co:JP Merlie " + co:JP Merlie psP65 + co:JP Merlie M169, M160 Yu pAchR g a m m a + co:L Yu MUSACHRA (microsat)+ co:JA Todd ).4, ~.7, )~4,1 Huppi pADP-C2,pADP-C3,pADP-C4 Huppi pADP3a, pADP2-1.1 Huppi pADP-C2 + co:K Huppi Akp-1 cDNAI, Hahnel Akp-1 cDNAII Hahnel TN-AP (PCR) Hahnel [H] plasmid eD98#7 Henthorn + Schurr + co:Henthorn(U Pa) I-AP genomic, I-AP cDNA M a n e s I-AP (PCR) Hahnel [H] peD98#7 + co:H Harris [HI pcD98#7 Henthorn + Schurr EAP genomic Manes EAP (PCR) Hahnel JR] pRMIS1 + co:RL Cate, Biogen pSPA2-16, pSPA2-3, Kunisada pSPA2-13, pSRA2-1 Kuniaada pSRA2-15 Kunisada Apoa-2 cDNA + co:AJ Lusis + co:AJ Lusis + co:AJ Lusis apoAII cDNA + co:AJ Lusis + Dowbenko Apoa-2 PCR/Cfr13I + Higuchi Apoa-2 PCR/Mspl + Higuchi [HI pAt3 B ock + Seldin " + Seldin + co:S Orkin [HI pAtlII-2 Prochownik + co: Seldin [R] rbl3c + co:DE H o u s m a n JR] zl3C + co:R Levenson + co:R Levenson + co:R Levenson [R] rbl9 Mercer " + Kent JR] rbl9G + co:R Levenson + co:Seldin Atpb-cDNA Gloor Ncm4 Gurfinkel co:Mushinski + Mock + Mock + co:Seldin [H] pB4, pB16 Tsujimoto ).114.2.1, ~.114.5.1 Negrini ).114.11.1, ~.114.11.2 Negrini ~.113.15.5, ~.114.11.3 Negrini pMBCL5.4, pMBCL3.3 Negrini pMBCL-3-4 + co:B Mock MMBCL2 (microsat) + Montagutelli clone 1, BCM-1 eDNA + W o n g BCM-1 cDNA + co:AF Williams + + +

Referencee

Science 1986; 234:1545 Genomics 1989; 4:221 reflWatson, M a m m Genome 1992; 2:158 Science 1986; 234:866 PNAS 1986; 83:8405 PNAS 1984; 81:7970 Science 1986; 234:866 Genomics 1990; 7:57 J Biol Chem 1986; 261:16451 ref:Copeland, Genomics 1991; 9:44 ref:Schurr, J Immunol 1989; 142:4507 ref:Schurr, Genomics 1990; 8:477 tel:Watson, M a m m Genome 1992; 2:158 Nucl Acid Res 1986; 14:3539 ref:Moen, M a m m Genome 1991; 1:217 ref:Hearne, M a m m Genome 1991; 1:273 Nucl Acid Res 1989; 17:3387 N u d Acid Res 1989; 17:3387 Nucl Acid Res 1989; 17:3387 ref:Watson, M a m m Genome 1992; 2:158 Clin Chim Acta 1989; 186:171 Clin Claim Acta 1989; 186:171 Development 1990; 555:564 PNAS 1987; 84:1234 Cytogenet Cell Genet 1989, 52:65 ref:Schurr, J Immunol 1989; 142:4507 Genomics 1990; 8:541 Development 1990; 555:564 ref:Watson, M a m m Genome 1992; 2:158 PNAS 1987; 84:1234 Cytogenet Cell Genet 1989; 52:65 Genomics 1990; 8:541 Development 1990; 555:564 ref:King, Genornics 1991; 11:273 Nucl Acid Res 1986; 14:5729 Nucl Acid Res 1986; 14:5729 Nucl Acid Res 1986; 14:5729 ref:Seldin, Genomica 1988; 2:48 ref:Seldin, J Exp Med 1988; 167:688 ref:Wataon, M a m m Genome 1992; 2:158 ref:Doolittle, J Biol Chem 1990; 265:16380 Genomics 1991; 9:270 Biochem J 1991; 279:427 Biochem J 1991; 279:427 Cytogenet Cell Genet 1985; 39:67 J Exp Meal 1988; 167:688 Genomics 1988; 2:48 ref:Watson, M a m m Genome 1992; 2:158 J Biol Chem 1983; 258:8389 ref: Dickinson, Genomic~ 1990; 6:505 ref: Kent, PNAS 1987; 84:5369 ref:Moseley, Genomics 1989; 5:899 ref:Kingsmore, EMBO J 1989; 8:4073 ref:Watson, M a m m Genome 1992; 2:158 Mol Cell Biol 1986; 6:3884 PNAS 1987; 84:5369 ref:Moseley, Genomlcs 1989; 5:899 ref:Watson, M a m m Genome 1992; 2:158 Nucl Acid Re~ 1989; 17:10117 Eur J Immtmol 1987; 17:567 ref:King, J Immtmol 1990; 144:3218 Cytogenet Cell Genet 1988; 47:11 Genomics 1990; 7:57 ref:Mamm Genome 1992; 2:158 PNAS 1986; 83:5214 Cell 1987; 49:455 Cell 1987; 49:455 Cell 1987; 49:455 Ceil 1987; 49:455 ref:Copeland, Genomics 1991; 9:44 M a m m Genome 1991; 1:255 J Exp Med 1990; 171:2115 ref:Watson, M a m m Genome 1992; 2:158 C o n t i n u e d on next p a g e

311

J.T. Eppig: Clones and Probes Table 3.

Continued.

Chr Symbola

~

Name

1

Bxv-1

B10 xenotropie virus-1

1

C4bp

complement component-4 binding prot

1 1

Cd3n Cd3z

T cell receptor complex Cd3-~ chain T cell receptor complex Cd3-~ chain

Cd28

CD28 antigen

Cd34 Cf-5

cluster designation 34 coagulation factor-5

Cfh

complement component factor h (H.2 allotype, B10.WR)

Co13a-1

(H.1 allotype, STR/N) procollagen type Ill a-1

Co16a-3

procollagen type VI a-3

Cr-2

complement receptor-2

c~p

C-reactive protein

Crry

complement receptor related protein Y (p65)

Cryb

J3 crystallin (also called Len-2)

Cryb-2 Cryg C ryg- 1

erystallin-2 (from +/+ mouse) (from Philly mouse) 7 crystallin complex T crystallin-1 (also called Len-1)

Cryg-2

T crystallin-2

Probeb

RFLVc C o n { ~ t

Referencee

J Virol 1989; 63:1763 J Virol 1982; 44:19 ref.'Hunter, Somat Cell Mol C-enet 1991; 17:169 Biochemistry 1987; 26:4668 pMBP.14, pMBP.15 J Exp Meal 1988; 167:688 pMBP.15 ref:Watson, M a m m Genome 1992; 2:158 ref:Watson, M a m m Genome 1992; 2:158 pBS17 Science 1988; 239:1018 T'3z cDNA Immunogenetics 1989; 29:265 ref.'Wataon, M a m m Genome 1992; 2:158 J Biol Chem 1989; 264:13252 clone 7, clone 11 J Biol Chem 1989; 264:13252 Tcrz-cDNA ref:Harper, J Immunol 1991; 147:1037 pGEMSZ-CD28-5' tel:Harper, J Immunol 1991; 147:1037 pGEMSZ-CD28-3' ref:Colombo, M a m m Genome 1992, 2:130 [HI Cd28 eDNA ref:Watson, M a m m Genome 1992; 2:158 ref:Watson, M a m m Genome 1992; 2:158 Cd34 eDNA refiWatson, J Exp Med 1990; 172:263 [H] FV eDNA tel:Watson, M a m m Genome 1992; 2:158 Cf-5 eDNA PNAS 1986; 83:3963 MH8, MH4 ref:D'Etmtachio, J Immunol 1986; 137:3990 MH8 ref:Seldin, Genomics 1988; :2:48 " ref:Nataumme-Sakai, J I m m u n 1990; 144:358 Genetics 1990; 125:431 tel:Watson, M a m m Genome 1992; 2:158 Cfh c D N A + co:BF Tack J Immunol 1990; 144:358 STR309 + Natsumme-Sakai ref:Liau, J Biol Chem 1985; 260:531 pMCSI co:deCrombugghe Gene 1987; 61:225 pCIII-I-C119,pCIII-I-C534 W o o d Gene 1967; 61:225 pCIII-I-C572 Wood ret~Metsaranta, BBA I991; 1089:241 pCot3al-1, pDT1505 co:E Vuorio ref:Colombo, M a m m Genome 1992; 2:130 pF-C + co:MP Mudryj ref:Watson, M a m m Genome 1992; 2:158 + co:MP Mudryj ref:Schurr, Genomics 1990; 8:477 [H] SD-1 + co:C Boyd Am J Hum Genet 1988; 42:435 [H] 1>24 W ei 1 Genomies 1990; 8:477 + Schurr pM1 Fingeroth PNAS 1989; 86:242 J Immtmol 1990; 144:3458 pM2 Fingeroth J Immtmol 1989; 143:2058 Zgl-1, Kurtz J Immtmol 1989; 143:2058 mCR2 1-1, 113-2, Kurtz J Immtmo11989; 143:2058 genomic phage 1-1, 3-3, 3-2 Kurtz J ImmtmoI 1990; 144:3581 eDNA 31-1,5-1,4-1,23-2,12 Kurtz phage 2-1,7-1,Z,B/B3,B/B5 Kurt.z J Immtmol 1990; 144:3581 J Immtmo11990; 145:2974 kMCR2-5 Molina ref:Watson, M a m m Genome 1992; 2:158 107-1 + co:JH Weis MCRP1 Whitehead Biochem J 1990; 266:283 Immunogenetic~ 1990; 32:36I " + Yunis refiKingsmore, EMBO J 1989; 8:4073 [H] pCRP5 + co:AS Whitehead + co:AS Whitehead ref:Watson, M a m m Genome 1992; 2:158 M22871 (micresat) + co:JA Todd ref:Hearne, M a m m Genome 1991; 1:273 M22871 (micresat) + co:JA Todd ref:Montagutelli, M a m m Genome 1991; 1:255 ~.Ygl-l, YgBH1.6 co:Weis ref:Aegerter-Shaw, J Immunol 1987; 138:3488 J Immunol 1988; 142:582 Spleen-5, Liver-10 Paul J Immunol 1990; 144:1988 phage Y1-2, YI-1, 8D, 2A, K22 Paul J Immtmol 1989; 143:2058 genomie Y1-2 Kurtz phage 1-1B, 1-1, 3-2 Kurtz J Immunol 1990; 144:3581 MScR-I.O + eo:JH Weis ref:Watson, M a m m Genome 1992; 2:158 ref.'Schurr, Cytogenet Cell Genet 1989; 52:65 pUC9~/2.1 + co:Tsui (Toronto) + eo:Tsui (Toronto) ref:Schurr, J Immunol 1989; 142:4507 ref:Schurr, Genomics 1990; 8:477 + co:Tsui pMJ3Crl J Biol Chem 1982; 257:9064 Inana Genes & Devel 1987; 1:637 Quinlan KSNM1, pGEMNM5 J Biol Chem 1991; 266:6742 Chambers pGEMPM2 J Biol Chem 1991; 266:6742 Chambers kMwtI C-ene 1991; 104:265 Graw ref:Quiulan. Genes & Dee 1987; 1:637 + co:Piatigorsky pMTla Shinohara PNAS 1982; 79.'2783 pMTI Biochem Genet 1988; 26:557 + Skow + Eicher Genetics 1990; 125:431 ref:Lok, Nucl Acid Res 1984; 12:4517 co:M Breitman PNAS 1982; 79:2763 Shinohara pMy2 Genomies 1990; 7 : 5 7 + Mock ref:Masaki, Genomics 1989; 5:259 + co:Piatigorsky ref:Lok, Nuel Acid Res 1984; 12:4517 + co:M Breitman Mol Cell Biol 1985; 5:2221 Lok XML2, pUCy2 ref:Quinlan, Genes & Dev 1987; 1:637 + eo:Piatigorsky XML2 + eo:CC Tsui (Toronto) ref:Schurr, Curr Top Micro Immun 1988;62:65 pMT-1Cr2 rof:Watson, M a m m Genome 1992; 2:158 + eo:CC Tsui JS-6flS-10 pMo-MCFI-I

+

Frankel Bosselman co:M Vogt Kristensen + Seldin + co:BF Tack + co:EL Reinherz Weissman Letourneur + co:RD Klausner Baniyash + Baniyash co:P Golstein co:P Golstoln + co:A Aruffo + co:B Seed + co:B Seed + co:E Guinto + co:RTA MacGillivray Kristensen + co:BF Tack + co:BF Tack + co:BF Tack + Eicher

C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

312 Table 3. Continued. Chr Symbola

Locus Name

1

Cryg-3

1

Cryg-4

1

Cryg-6

1

Ctla-4

1 1 1 1 1 1 1 1

DIBh149 DiFcrl "D1H18" "D1H37" "D1H46" "D1H49" D1Lehl D1Lubl

Shinohara,Breitman,Quinlan (see Cryg-1, Cryg-2 above) co:M Breitman ref:Lok, Nucl Acid Res 1984; 12:4517 Shinohara,Breitman,Quinlan (see Cryg-1, Cryg-2 above) T crystallin-4 pMT4 co:Piatigorsky ref:Masaki, Genornics 1989; 5:259 rehLok, Nucl Acid Res 1984; 12:4517 co:M Breitman Lok Nucl Acid Res 1987; 12:4517 kML1 Breitman PNAS 1984; 81:7762 crystallin-6 Nucl Acid Re~ 1984; 12:4517 76 clone Lok ref:Quinlan, Genes & Dev 1987; 1:637 Cryg-6 c D N A + co:Piatigorsky cytotoxic T lymphocyte associated pretein-4 M17G7, F51G9 Brunet Nature 1987; 328:267 F41F4 Brunet Nature 1987; 328:267 + Mock Genomics 1989; 5:291 + co:P Golstein ref:Copeland, Genomics 1991; 9:44 + co,JF Brunet ref:Colombo, M a m m Genome 1992; 2:130 + co:P Golstein ref:Watson, M a m m Genome 1992; 2:158 co:P Golstein ref:Harper, J Immlmol 1991; 147:1037 MoCTLA-4 DNA segment, Chr 1, Buchberg-149 pBH149.5a + co:Buchberg ref:Dickiuson, Genomics 1990; 6:505 DNA segment, Chr 1, Frederick Canc Res-1 p2R-4.4ss + Copeland Genomics 1991; 9:44 DNA segment, Chr 1, H18 cosmid H18 Boyle Genomics 1992; 12:106 DNA segment, Chr 1, H37 cosmid H37 Genomics 1992; 12:106 Boyle DNA segment, Chr 1, H46 cosmid H46 Genomics 1992; 12:106 Boyle DNA segment, Chr 1, H49 cosmid H49 Genomics 1992; 12:106 Boyle DNA segment, Chr 1, Lehrach-1 P e R Line 6589 + Cox Genomics 1991; 10:375 DNA segment, Chr 1, Lubeck-1 kMmHSR1009 + Boldyreff Cytogenet Cell C,enet 1988; 47:84 (homogeneous staining region) EMBO J 1987; 6:1295 Weith pMmHSR5 co:H Winking rei}Eckert, Mol Cell Biol 1991; 11:2229 pMmHSRc-I,pMmHSRc-3, co:H W i n k i n g ref:Eckert, Mol Cell Biol 1991; 11:2229 pMmHSRc-3E,pMmHSRc-4, co:H Winking ref:Eckert, Mol Cell Biol 1991; 11:2229 pMmHSRc-10,pMmHSRc-10E co:H Winking ref:Eckert, Mol Cell Biol 1991; 11:2229 DNA segment, Chr 1, Lubeck-2 pMmHSR5 ce:H W i n k i n g ref:Eckert, Mol Cell Biol 1991; 11:2229 (homogeneous staining region) (DNA segment,within Ncl, see Ncl) DNA segment, Chr 1, Pasteur Inst-1 PL10 Leroy Devel 1987; 101 (supp): 177 (testis specific transcript) Cell 1989; 57:549 Leroy + Kingsmore Immunogenetics 1989; 30:169 EMBO J 1989; 8:4073 + Kingsmore + co:Seldin ref:Watson, M a m m Genome 1992; 2:158 DNA segment, Chr 1, Res Triangle Inst-2 pMEI + Cobb Genomic~ 1992; 12:405 DNA segment, Chr 1, h u m a n D2S3 [H] p5-1-25 Lit~ Nucl Acid Res 1986; 14:4378 Genomics 1990; 7:57 § Mock desmin Genet Res 1990; 55:101 [HI BHudes07 Li endothelial adhesion molecule [H] ELAM.1 eDNA § co: Seed, Bevilacqua ref:Watson, J Exp Med 1990; 172:263 + co:B Seed ref:Watson, M a m m Genome 1992; 2:158 [HI Elam probe + co:M Bevilacqua ref:Singh, PNAS 1991; 88:10706 endogenous ecotrepic MuLV-16 pEce Chattopadhyay PNAS 1980; 77:5774 ref:Jenkins, Cell 1985; 43:811 + co:NG Copeland endogenous ecotropic MuLV-17 Emv-17 DNA co:Copeland ref:Buchberg, J Virology 1986; 60:1175 pPS1.25 + co:Copeland ref:Buchberg, J Virology 1986; 60:1175 ref:Moore, OenetScs 1988; 119:933 + co:Copeland pEce Chattopadhyay PNAS 1980; 77:5774 + co:NG Copeland ref:Jenkins, Cell 1985; 43:811 endogenous ecotropic MuLV-20 pEce Chattopadhyay PNAS 1980; 77:5774 pEc-B4 Chan PNAS 1980; 77'.~79 pEco, pEc-B4 + Taylor Genomics 1989; 5:221 engrailed-1 Cytogenet Cell C,enet 1987; 44:171 ~4U6 + co:Hill Development 1988; 104:305 I~%4,p~4U6,1~%4L7 Davidson ~.Mo-en. 1 Joyner Cell 1985; 43:29 En- lc Joyner Genes & Devel 1987; 1:29 mp + Joyner Genes & Devel 1987; 1:29 + co:A Joyner ref:Copeland, Genomic~ 1991; 9:44 + co:GR Martin ref:Watson, M a m m Genome 1992; 2:158 epoxide hydrolase- 1 [R] pEH-1 Gonzales J Biol Chem 1981; 256:4697 J Biol Chem 1985; 260:515 Simmons + co:CB Kasper ref:Watson, M a m m Genome 1992; 2:158 Fc epsilon high affinity receptor a [R] FceRIa Kinet Biochemistry 1987; 26:4605 J Immunol 1988; 141:2807 + Huppi + co:J-P Kinet ref:Moseley, Genom]cs 1989; 5:899 + co:J-P Kinet ref:Kingsmore, EMBO J 1989; 8:4073 Fcela eDNA + co:J-P Kinet ref:Watson, M a m m Genome 1992; 2:158 Fc epsilon high affinity receptor 7 clones D13-2, D13-3 Sears J Immunology 1990; 144:371 J774 Ravetch Science 1986; 234:718 J Immunol 1988; 141:2807 + Huppi pFc24 Hibbs PNAS 1986; 83.'6980 Fcelg c D N A + co:J-P Kinet ref:Wat~on, M a m m Genome 1992; 2:158 Fc epsilon low affinity receptor FCeRII c D N A Bettler PNAS 1989; 86:7566

"D1Lub2" D1Nds28 D1Pasl

D1Rti2 D2S3h Des

Elam Emv- 16 Emv- 17

Emw20 En-1

Eph-i

Fcerla

Fcerlg

Fcer'2

7 crystallin-3

Probeb

pM~

RFLVc Coat~td

Refemocee

+ + + +

Continued on next p a g e

J.T. Eppig: Clones and Probes Table 3.

Continued.

Chr Symbola

1

313

Fcgr2

~

Name

Fe low affinity IgG receptor 3 (aFcgR) (also called Ly-17)

(Fc low affinity receptor 7 2a) (Fc low affinityreceptor 7 2b)

1

Fcgr3

Fc low affinity IgG receptor 3 (aFcgR)

1

Fn-1

fibronectin-1

1

Gas-10

growth arrest specific-10

1

Gls

glutaminase

1

Grmp

granulocyte membrane protein

1 1

Gsh-4 Hlx

genomic screened homeobox-4 H2.0 like homeo box gene

1 1

Iap(Rem2) intracisternal A particle, Ren-2 linked Ifi201 interferon activated gene 201

1

Ifi202

interferon activated gene 202

1

Ifi203

interferon activated gene 203

1

Ifi204

interferon activated gene 204

1 1

Igfbp-2 I1 lr-1

i 1

"Illr-2" Inha

insulin-like growth factor binding prot-2 interleukin 1 receptor, type I (T cell, fibroblast) interleukin 1 receptor, type II inhibin a

1

Inhbb

inhibin ~B

~

RFLVc C o n t ~

Nature 1986; 324:372 Science 1986; 234:718 refiHuppi, J Immunoi 1988; 141:2807 ref:Seldin, Genornics 1988; 2:48 Immunogenetice 1989; 30:169 EMBO J 1989; 8:4073 Nucl Acid Res 1990; 18:5281 J Immunol 1990; 144:1974 J Immunol 1991; 147:1067 r e f : W a t s o n , M a m m Genome 1992; 2:158 Science 1990; 248:732 PNAS 1990; 872856 Science 1990; 248:732 PNAS 1990; 87.'2856 ref:Watson, M a m m Genome 1992; 2:158 Science 1986; 234:718 J Exp Med 1988; 1 6 7 : ~ Mol Immunol 1992; 29:353 Mol Immunol 1992; 29:353 PNAS 1983; 80:3218 Genomice 1987; 1:283 ref:Schurr, J Immunol 1989; 142:4507 EMBO J 1987; 6"=2265 Ctwr Top Microbiol Immuno] 1988; 137:310 " + Schurr [R] BXB32.5 + co:RO Hynes(MIT) ref:Schurr, J Immunol 1989; 142:4507 ref:Schurr, Genomics 1990; 8:477 " + co:RO Hynes J Ne~ Res 1990;27:144 clone 1>47 Rhyner ref:Wamon, Mamm Genome 1992; 2:158 prlf-1 + co:RO Hynes rehColombo, Mamm Genome1992; 2:130 Gas-10 cDNA + co:P D'Eustachio " + co:Schneider,Colombo tel:Watson, MammGenome 1992; 2:158 Mol Brain Res 1988; 3:247 JR] pGA1 Banner Genomics1989; 5:291 + Mock tel:Colombo, Mamm Genome 1992; 2:130 + co:B Mock tel:Watson, Mamm Genome 1992; 2:158 + co:M Seldin J Exp Med 1990; 172:263 [H] GMP-140 + Watson refiWatson, MammGenome 1992; 2:158 E4 + co:RP McEver PNAS 1991;88:10706 clone 71h + Singh Genes & Devel 1991; 5:509 ml, m3 Allen Genes & Devel 1991; 5:509 j15 + Allen Nucl Acid Res 1984; 12:8579 pDBRn3, MIARN Burt ref:Opdenakker, Virology 1989; 171:568 cesmid3.1, cosmid2A, co:P Lengyel ref:Opdenakker, Virology 1989; 171:568 cosmid6.1, cosmidH co:P Lengyel J Biol Chem 1989; 264:17182 1050-22, cosmid3.1 Choubey J Biol Chem 1986; 261:11849 clone 2, 3, 4, 5, p922 Samanta Immunogenetics 1989; 30:169 + Kingsmore F2dBO J 1989; 8:4073 clone 202-exon 1 + Kingsmore ref:Watson, M a m m Genome 1992; 2:158 + co:P Lengyel cosmid3.1, cosmid2A, co:P Lengyel ref:Opdenakker, Virology 1989; 171:568 cosmid6.1, cosmidH co:P Lengyel ref:Opdenakker, Virology 1989; 171:568 Virology 1989; 171:568 p922 + Opdenakker pHl.l,cosmidH1, 4a,14,17a Choubey J Biol Chem 1989; 264:17182 genomic clone 5 Engel Virology 1988; 166:24 Virology 1989; 171:568 203.2 + Opdenakker Immunogenetics 1989; 30:169 + Kingsmore + Kingsmore EMBO J 1989; 8:4073 cesmid3.1, cosmid2A, co:P Lengyel ref:Opdenakker, Virology 1989; 171:568 cosmid6.1, cosmidH co:P Lengyel ref:Opdenakker, Virology 1989; 171:568 genomic clone 5 Engel Virology 1988; 168:24 Virology 1989; 171:568 204-eDNA Opdenakker clone 17b + Kingsmore Immunogenetics 1989; 30:169 EMBO J 1989; 8:4073 + Kingsmore cesmid3.1, cosmid2A, co:P Lengyel refiOpdenakker, Virology 1989; 171:568 cosmid6.1, cosmidH co:P Lengyel ref:Opdenakker, Virology 1989; 171:568 p25-33, cosmidl8.2, 17b Choubey J Biol Chem 1989; 264:17182 [H]AS200 co:A Swaroop ref:Agarwal, Exp Eye Res 199:[; 52:549 [H] pG78.Int Sims Science 1988; 241:585 ref:Copeland, Genomics 1991; 9:44 + co:A Sims Mull2 + McMahan EMBO J 1991; 10:2821 [H] ~.hina-2 Mason BBRC 1986; 135.'957 ~H] Xhina-6 Mason BBRC 1986; 135:957 [H] Inha eDNA(derived) co:AJ Mason ref:Barton, Genomics 1989; 5:91 6~ + co:AJ Mason ref:Watson, M a m m Genome 1992; 2:158 [H] ~hinJ3B-3 Mason BBRC 1986; 135:957 [H] khin~B-16 Mason BBRC 1986; 135:957 [H] ~,hin~B-2s Mason BBRC 1986; 135:957 [H] Inhbb cDNA (derived) co:AJ Mason ref:Barton,Genomics 1989; 5:91 pFcRAb,pFcR11,pFcR13 Lewis FcTRa , FcTR]31, FcTR~2 Ravetch FcTRa + co:Ravetch + co:Ravetch + Kingsmore + Kingsmore Ly-17 DNA Weliman p23.18, pL23.6 Gollnick Richards danes 12.2, 3.1, 2a Fcl~l + eo:JV Ravetch Fcrg2a cDNA Qiu B3.7, B3.9, R2.5, R10.1 Kulczycki J r Fcrg2b cDNA Qiu clone 1-1,clone 5-1,clone 4-5 Kulczycki J r FcRa + co:Ravetch Ravetch + Seldin LaAKR, SaAKR, Bonnerot aBALB/c Bonnerot [H] pFN-1 Kornblihtt " + Skow + co:Skow(Tx A&M) [It] Fn eDNA Patel

C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

314 Table 3. Continued. Chr Symbola

~Name

1

Kras-1

Kirsten rat sarcoma oncogene-1, pseudo

1

Lamb2

laminin B2

Probeb

R F L V c Contactd

[H] pSWII-I " pPE9

+ + +

co:ATCC co:R Weinberg co:Elliott

+ + +

Durkin Durkin Kaye Sasaki co:Y Yamada eo:Y Yamada co:A Chung

p16,1)57, p54, ~94, ~573 X281, X34, ~ p54 p7 Lamb2 cDNA Len-1 Len-2 Lnhr

see Cryb lymph node homing receptor

[H] h L H R c LHR cDNA M , ~.7,;~8 Lnhr c D N A

+ + +

+ + lymphocyte antigen-5 (also called Cd45)

MT4-T200 pLy-5-68

"

pLyS-68 pLy-5-R1, pLy-5-R2, pLy-5-R3, pLy-5-R4, pLy-5 genomic pLy-5-B11, pLy-5-B15 pLy-T4, pLy-5-B12 XmLC-1, XmLC-2, LMGLC-6A ,XmGLC-9, kMGLC-26 probe A (from clone 70) probe B (from clone 1) clones: 1,2,6,17,27,34,35 clones: 42,45,47,49,70 Ly-5 oligo 51 Ly-17 Mintb Mmv-5

(withdrawn, see Fcgr2) MuLV integration/expression site, EC b cells pBS416 MCF endogenous virus-5 pMo-MCFI-1

Mmv-9

MCF endogenous virus-9

pMo-MCFI-1

Mmv-14 "Mns-l"

MCF endogenous virus-14 minor satellite Chr 1 (centromeric)

MCF100 pMR150

Mov-7 Mov-7(f) Mpmv-6

Moloney leukemia virus-7 pMov-7, pMov-7-1-2 Mov-7 flank p7-1-1 modified polytropic murine leukemia virus-6 JS-4 JS-4 JH modified polytropic routine leukemia virus-16 JS-4 modified polytropic murine leukemia virus-22 JS-4 modified polytropic routine leukemia virus-25 JS-4 pMo-MCFI-16 modified polytropic murine leukemia virus-29 JS-4 modified polytropic murine leukemia virus-32 JS-4, MCF100 modified polytrepic murine leukemia virus-34 JS-4, MCF100 modified tmlytropic routine leukemia virus-35 JS-4, MCF100 modified polytropic murine leukemia virus-37 JS-4 modified polytrepic murine leukemia virus-42 JS-4 peripheral myelin protein [R] pSN63

Mpmv-16 Mpmv-22 Mpmv-25

ref:Dickinson, Genomics 1990; 6:505 refiWatson, M a m m Genome 1992; 2:158 In Vitro Cell Devel Biol 1985; 21:477 Biochemistry 1988; 27:5198 Biochemistry 1988; 27:5198 Somatic Cell Mol Genet 1990; 16:599 J Biol Chem 1987; 262:17111 ref:Seldin, Genomics 1989; 4:221 ref:Watson, M a m m Genome 1992; 2:158 ref:Danciger, Cytogen Cell Genet 1991; 56:202

see Cryg

mLHRc Ly-5

Referencee

1 1 1 1 1 1 1

Mpmv-29 Mpmv-32 Mpmv-34 Mpmv-35 Mpmv-37 Mpmv-42 Mpp

1 1 1 1 1

~Msl-3-2-P2" minisatellite 1-3-2-P2 (Drosophila Per) 'TIs1-2-4-P2" minisatellite 1-2-4-P2 (Drosophila Per) "Ms2-2-16-Pl" minisatellite2-2-16-P1 (human DIS57) ~Ms2-2-17-P2" minisatellite2-2-17-P2 (human DIS57) ~Ms4-1-11-P2" minisatellite4-1-11-P2 (human D2S44)

I 1 1

'~MsI0-2-6-P2" minisatellite I0-2-6-P2 (human D17S5) pYNZ22 "Ms10-2-7-P1" minisatellite 10-2-7-P1 (human D17S5) pYNZ22 Mtap-4 microtubule-associated protein-4 M3, M4, M7, M9, M31

pSP.2.5.EI pSP.2.5.EI pYNZ2 pYNZ2 pYNH24

+ + + + +

+

+ + + +

+

+ + + + + + + + + + + + + +

+ + + + + + +

co:F-W Shen Saga Saga Saga Saga Saga Thomas Thomas Thomas Saga Saga Saga Saga co:WC Raschke

J Exp Med 1990;, 172:263 J Exp Med 1990; 172:263 Genomics 1991; 9:270 Genomics 1991; 9:270 Science 243:1165 Cell 1990; 61:611 ref:Watson, M a m m Genome 1992; 2:158 PNAS 1987; 84:161 PNAS 1985; 82:7360 J Exp Med 1988; 167:688 Genomics 1988; 2:48 Immunogenetics 1987; 26:74 ref:Cox, Genomics 1991; 10:375 ref:Watson, M a m m Genome 1992; 2:158 PNAS 1986; 83:6940 PNAS 1986; 83:6940 PNAS 1986; 83:6940 PNAS 1987; 84:5364 PNAS 1987; 64:5364 PNAS 1987; 84:5360 PNAS 1987; 84:5360 PNAS 1987; 84:5360 Mel Cell Biol 1988; 8:4889 Mol Cell Biol 1988; 8:4889 Mol Cell Biol 1988; 8:4889 Mol Cell Biol 1988; 8:4889 refiZebedee, Eur J Immunogenet 1991; 18:155

co:M Taketo Bosselman co:M Vogt Bosselman co:M Vogt Frankel Voliva co:VM C h a p m a n co:ND Hastie co:R Jaenisch M unke Frankel Frankel co:W Frankel Frankel Frankel Frankel co:M Vogt Frankel Frankel Frankel Frankel Frankel Frankel Lemke co:G L e m k e Julier Julier Julier Julier Julier Julier Julier co:JB Olmsted

refiWatson, M a m m Genome 1992; 2:158 J Viral 1982; 44:19 refiHunter, Sornat Cell Mol Genet 1991; 17:169 J Viral 1982; 44:19 reflHunter, Somat CellMol Genet 1991; 17:169 M a m m Genome 1992; 2:110 Nucl Acid Res 1983; 11:8847 ref:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1983; 11:6965 ref:Chumakov, J Virol 1982; 42:1088 Cytogenet Cell Genet 1986; 43:140 Genetics 1990; 124:221 M a m m Genome 1992; 2:110 ref:Gerstein, Cell 1990; 63:537 Genetics 1990; 124:221 Genetics 1990; 124:221 Genetics 1990; 124:221 ref:Blatt, PNAS 1983; 80:6298 Genetics 1990; 124:221 Mamrn Genome 1992; 2:110 M a m m Genome 1992; 2:110 M a m m Genome 1992; 2:110 M a m m Genome 1992; 2:110 M a m m Geneme 1992; 2:110 Cell 1985; 40:501 ref:Kuhn, J Neure6cience 1990; 10:205 PNAS 1990; 87:4585 PNAS 1990;87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 refiWest, J Biel Chem 1991; 266:21886

Watson Watson Dowbendo Dowbendo

Siegelman Siegelman co:MH Siegelman Raschke Shen Seldin Seldin Seldin c o : W D Davidson

C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

315

Table 3, Continued. CI~" Symbola

1

Mtv-7

Lcx:usName

m a m m a r y tumor virus locus-7

1

Mtv-27

m a m m a r y tumor virus locus-27

1

Mtv-39

1

Mylf

m a m m a r y tumor virus locus-39 (called Mtv-29 in reference) myosin light chain, alkali, fast skeletal muscle

P~e b

RFLVc C ~ a ~ 1

[V]MMTV(C3H) probe

Maclnnes

+

Natm-e 1985; 314:181 co:B Robert J Biol Chem 1985; 2~.8578 Barton J Muscle Res & Ceil Motility 1985; 6:461 Barton Cell 1984; 39:129 Robert Cell 1984; 39:129 Robert Cell 1984; 39:129 Robert ref:Mock, Genomics 1990; 7:57 co:B Robert ref:Yelick, Genomics 1991; 11:687 eo:BRobert, Guenet tel:Watson, M a m m Genome 1992; 2:158 co:B Robert G e n o m i c s 1990; 8:427 Olson ref:Hearne, M a m m Genome 1991; 1:273 eo:JA Todd Cell 1989; 56:607 Wright Am J Hum Genet 1990; 47:483 Franeke J Mol Biol 1988; 200:627 Bourbon J Mol Biel 1988; 200:627 Bourbon J Mot Biol 1988; 200:627 Bourbon ref.'Aitman, M a m m Genome 1991; 1:206 co:JA Todd PNAS 1992; 89:38 Begley Mouse News Letter 1985; 71:46 co:Elliott J Biol Chem 1984; 259:7941 co:FG Berger Mol Endocrinol 1989; 3:1243 Rheaume ref:Sirac~sa, Genetics 1991; :[27:169 co:FG Berger Nuel Acid Res 1990; 18:1634 Goldsborough Genomics 1990; 6:666 Hsieh Genes & Devel 1988; 2:1582 Sturm Genomics 1991; 10:313 Siracusa ref:Watson, M a m m Genome 1992; 2:158 co:RA S t u r m Genomics 1991; 10:313 Siraeusa EMBO J 1991; 10:1135 Goulding Cell 1991; 67:767 Epstein J Virol 1989; 63:3810 Frankel J Virol 1989; 63:3810 Fraukel J Virol 1982; 44:19 Bosselman ref.'Hnnter, Somat Cell Mol Genet 1991; 17:169 co:M Vogt J Virol 1989; 63:3810 Frankel M a m m Genome 1992; 2:110 Frankel M a m m Genome 1992; 2:110 Frankel Genomics 1991; 9:642 Adler Somatic Cell Mol Genet 1984; 10:633 Chirgwin Somatic Cell Mol Genet 1984; 10:633 Chirgwin PNAS 1984; 815489 Panthier Nuel Acid Res 1989; 17:9480 Kim Nucl Acid Res 1988; 16:2111 Abel co:E Geissler (MIT) ref.'Schurr, Cytogenet Cell Genet 1989; 52:65 co:E Geissler (MIT) ref:Sehurr, Genomics 1990; 8:477 EMBOJ 1982; 1:1461 Mullins in:Kostka (ed), 1985, Aspartic Proteinases and Burr Their Inhibitors, Berlin, p462 Mol Cell Biol 1984; 4:2321 Field Gene 1989; 84:91 Butt ref:Abel, Genetics 1990; 124:937 eo:D Burt Gene 1989; 84:91 Burr Hypertension 1984; 6:597 Field ref:Piecini, Cell 1982;30:205 co:Gross Genetics 1984; 108:6,51 Dickinson ref:Panthier, EMBO J 1982; 1:1417 eo:F Rougeon contributed probe eo:F Rougeon PNAS 1981; 78.~367 Rougeon Nature 1982; 298:90 Panthier Hypertension 1984; 6:597 Field

Traina eo:J Ball, J Majors MMTV eDNA or DNA MMTV eDNA + Michalides MMTV-LTR + Michalides + co:R Callahan ev-8, pve-28 + co:Michalides MMTVS-21,MMTVS-29 + Lee pTZl8R-ORF + co:JE Majors MMTVS-29, MMTVS-21 Majors M M T V 8-29 + Eicher MMTV 8-21 + Eieher MMTV8-21 + co'JE Majors pGIX~450

+

Myog

1 1

Ncf-2 Ncl

"Nscl" Odc-rsl

pGLC1012 + myogenin Myog eDNA + MMMYOGG1 (microsat)+ pBV65 neutrophil eytesolic factor-2 [HI NCF2-10 + nucleolin kHB3, HBc21, pSPB26, l~_qPB9,pSPEB32, pSPE32, pSPE9, Nucl eDNA (D1Nds28) MMNUCLEO (microsat) + nervous system homolog of h u m a n SCL gene Nscl eDNA + ornithine decarboxylase-related seq-1 pMK934 + pODC'934 pCR6 (pDOC934 derived) +

Off-1

octamer-binding transcription factor-1

Otf3-rsl Pax-3

Otf-3 related sequence-i paired box homeotie gene-3

Pmv-21 Pmv-24

polytropic murine leukemia virus-21 polytropic murine leukemSa virus-24

Pmv-44

polytropie murine leukemia virus-44

Oct-1 eDNA [H] pBSXSI.I [HI XCS, ).C7 [HI Otf-1 eDNA pBS
+ + + + + + +

n

JS-5

+ +

Pmv-45 Prim2 Ren- 1

polytropie murine leukemia virus-45 DNA primasc, p58 subunit renin-1, structural

JS-5, MCF100 pcmLP MS, M9, M14, M16 r49probe SW35, SW83, ppRnl Ren-I-eDNA p3'Ren-1 pDBA-Rn8

+

+ +

pSMG199, pSMG213 pSMG5913

(from DBM2J)

Ren-l,-2

(from C57BLq0) renin-1,-2

~.BALB1 genomic Ren-1 d pRn34, pRn26-, p5'34X/P genomic Ren-1 c pSM479 + +

pRnl-4 pRnl-3 pRn3-5 (=pRnS.3) pRn5.3, pRn4.7 pK-A1

Virology 1984; 132:12 J Virol 1981; 40:735 ref:Maelnnes, Virology 1984; 132:12 Virology 1985; 142:278 Virology 1985; 142:278 ref:Danciger, Cytogen Cell Genet 1991; 56:202 ref:Moen, M a m m Genome 1991; 1:217 J Virol 1990; 64:4568 ref:Pullee, J Exp Med 1992; 175:41 Nature 1981; 289:253 Genetics 1990; 125:431 Genetics 1990; 125:431 ref:Siracusa, Genetics 1991; 127:169

+ +

+ p161, Type A ~, Type B ~ Type C ~, Mylf-ps genomic pGLC101 + 1

Refe~aeee

+ +

C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

316 Table 3, Continued.

crr Symtda

1

Ren-l,-2

La~Name

renin-1,-2

Probeb

RFLW C~tactd

pDD-1D2

Field Seldin Seldin co:Gross Dickinson + co:Gross + Mock + co:KW Gross ",p3'WX Abel Ren-2 eosmid Field pS'Ren2X/R Abel SW20,SWl0,SW90,ppRn2 P a n t h i e r Id-2 + co:D Dickinson psPe~-Vl Lund Rnul-1 DNA Moussa pU1.3 + Blatt pPHwSB.4 Mazan pmbe P, probe U Mazan [R] Pdc cDNA + Craft + co:CM Craft Abe [RI RRC-11 + Danciger Msc-242 + Danciger 48K cDNA Farber + + +

1

Ren-2

renin-2

1

Rnul-1

U1 small nuclear RNA-1

1 1

Rnul-psl Rnu3b-psl

U1 small nuclear RNA-1 pseudogene-1 U3B small nuclear RNA-3 pseudogene 1

i

Rpr- I

rod photorecepter-1

1

Sag

retinal S-antigen (48kDa)

Sag eDNA

Tsuda +

1

Sap

s e r u m amyloid P-component

MGS-2, MGS-3, MGS-5, MGS-30, MGS-91, MGS-93, MGS-95, COS-5 rpSAG 14 + pmSAP3 + + Sap eDNA, Sap genomic MSAP5 + + + + + +

1 1

"Snrpla-rsl" sma]t nuclear U1 RNA polypeptide A related sequence 1 Spna-1 a-spectrin-1, erythroid

U1PA

+

pMaSpl

Curtis co:PJ Curtis + co:PJ Curtis + co: Mock, Curtis + Kingsmore + Seidin + co:PJ Curtis + co:PJ Curtis Cioe + Birkenmeier + Seldin + eo:J Keene Tominaga + Tominaga Tomi n a g a Klemenz Barton Madisen Miller 4co:DA Miller + co:DA Miller Pelton eo:G Bell Kleene Kleene Heidaran + co:NB Hecht + co:NB Hecht PringauIt + Rousseau-Merck + Mock + co:J-L Guenet + co:E Pringault +

pB129 M

1 1

"Ssa" "St2"

60 kD Re antigen signal transduction-2

1

Tgfb-2

transforming growth factor, 6-2

1

1

Tp-1

Vil

Danciger ce:T Shinohara co:T Shinohara co:T Shinohara eo:CM Craft co:Maruyama co:Maruyama Nishiguchi Whitehead co:AS Whitehead Kingsmore co:AS Whitehead Yunis co:AS Whitehead co:J Keene

pRoUT clone 87 ST2 eDNA ST2G pTl.10, pT1.11 [HI Tgi~2 eDNA Tgtb-2 eDNA mTGF-~2-27

transition protein-1

frag of mTGF-~2-27 [I-I] Tgib-2 full eDNA pCE3,HSAR700

villin

[R]kMH19M2 Tp-1 genomie Tp-1 eDNA [HI p6P64

Ref~e

Hypertension 1984; 6:597 J Exp Med 1988; 167:688 Genomics 1988; 2:48 PNAS 1984; 81:5489 Genetics 1984; 108:651 ref:Dickinson, Genomics 1990; 6:505 Genomics 1990; 7:57 ref:Wataon, M a m m Genome 1992; 2:158 Nucl Acid Res 1988; 16:2111 Mol Cell Biol 1984; 4:2321 Genetics 1990; 124:937 PNAS 1984; 81:5489 ref:Copeland, Genomics 1991; 9:44 Science 1985; 229:1271 Nuel Acid Re8 1987; 15:3622 Somatic Cell Mol Genet 1988; 14:133 E u r J Biochem 1989; 181:599 Cytogenet Cell Genet 1991; 56:18 Genomics 1991; 10:400 ref:Wataon, M a m m Geoome 1992; 2:158 C-ene 1990; 91:209 Cytogenet Cell Genet 1991; 56:202 Genomics 1989; 5'.378 In:Inherited and Environmentally Induced Retinal Degenerations, Alan Lisa, 1989; p 143 Gone 1988; 73:11 Cytogenet Cell Genet 1991; 56:202 ref:Tsuda, Eur J Biochem 1991; 200:95 ref:Tsuda, Eur J Biochem 1991; 200:95 ref:Tsuda, Eur J Biochem 1991; 200:95 ref:Wat~on, Mamra Genome 1992; 2:158 ref:Ishikawa, Nucl Acid Res 1987; 15:7186 Biochem Genet 1989; 27:229 BBRC 1988; 155:1366 Immunogenetics 1988; 28:388 ref:Moseley, Genomics 1989; 5:899 Immunogenetics 1989; 30:169 ref:Kingsmore, EMBO J 1989; 8:4073 Immunogenetics 1990; 32:361 tel:Watson, M a m m Genome 1992; 2:158 refiWatson, M a m m Genome 1992; 2:158 Gene 1985; 36:357 ref: Huppi, 1988, J Immunol 141:2807 ref: Seldin, Genomics 1988; 2:48 ref: Dickinson, Genomics 1990; 6:505 Immunogenetics 1989; 30:169 Cytogenet Cell Genet 1987; 45:52 ref:Kingsmore, EMBO J 1989; 8:4073 tel:Watson, M a m m Genome 1992; 2:158 PNAS 1985; 82:1367 PNAS 1988; 8 5 : 8 1 2 1 J Exp Med 1988; 167:688 ref:Wat~on, M a m m Genome 1992; 2:158 FEBS Left 1989, 258:301 Biochim Biophys Acta 1991; 1090:1 Biochim Biophys Aeta 1991; 1090:1 PNAS 1989; 86:5708 Oocogene Res 1988; 3:323 DNA 1988; 7:1 Mol Endocrinol 1989; 3:1108 ref:Dickinson, Genornics 1990; 6:505 ref:Watson, M a m m Genome 1992; 2:158 Development 1990; 110:609 ref:Millan, Development 1991; 111:131 Devel Biol 1983; 98:455 BBA 1988; 950:215 Gene 1989; 75:39 ref:Yelick, Genomics 1991; 11:687 ref:Wat~on, M a m m Genome 1992; 2:158 EMBO J 1986; 5:3119 H u m Genet 1988; 78:130 Genomics 1990; 7:57 ref:Yelick, Genomics 1991; 11:687 ref:Wat~on, M a m m Genome 1992; 2:158 Continued on next p a g e

317

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Symbola

1

~

Name

Probeb

Vil

villin

1 1

Wnt-6 Xmmv-6 Xmmv-9

1 1

Xrnmv-36 Xmv-21

wing]ess-related MMTV integration site-6 Wnt-6 eDNA (withdrawn, see Mpmv-25) pMo-MCFI-16 xenotropic-MCF leukemia virus-9 pXenv pMo-MCFI-16 xenotropic-MCF leukemia virus-36 xenotropic routine leukemia virus-21 JS-6+JS-10

1 1 2 2

Xmv-32 Xmv-41 a Abl

xenotropic murine leukemia virus-32 xenotropic murine leukemia virus-41 non-agouti (see Emv-15) Abelson murine leukemia oncogene

1

RFLVc C o n t ~ d

[H] pEX2

"

JS-6+JS-10 JS-6+JS-10

+ +

co:J-L Ouenet co:J-L Guenet Gavin

ref:Schurr, J Immunol 1989; 142:4507 refiSchurr, Genomics 1990; 8:477 Genes & Development 1990; 4:2319

+ + + +

co:M Vogt co:MA Martin co:M Vogt Frankel Frankel Frankel Frankel

ref:Blatt, PNAS 1983; 80:6298 ref:Wejman, J Virol 1984; 50:237 ref:Blatt, PNAS 1983; 80:6298 J Viroi 1989; 63:1763 M a m m Genome 1992; 2:110 J Virol 1989; 63:1763 J Virol 1989; 63:1763

Srinivasan Salinas co:SJ O'Brien co:F Mushinski co:Srinivasan Stub~ co:Oncor Golf co:S Goff (Columbia) Wang Trakhtenbrot Meijer Meijer Wang Wa ng Ben-Neriah co:GQ Daley Dymecki Bernards Ben-Neriah Bernards Ben-Neriah Bernards Ben-Neriah Bernards Ben-Neriah Geier co:Heidmann co:Mock, Merlie Isenberg Merlie co~P Merlie Degen co:J Boulter (Salk) Alonso Minty co:Buckingham Garner Robert Garner Leader Czosnek co:U Nudel co:U Nudel Ingolia Stallings co:RE Kellems co:RE Kellems co:RE Kellems co:RE Kellems Yeung Yeung Al-Ubaidi co:JA Todd

PNAS 1981; 78:2077 E u r J Biochem 1986; 160:149 ref:Threadgill, Genomics 1988; 3:82 ref:Joziasse, Som Cell Mol Genet 1991; 17:201 ref:Meruelo, Immunogenetics 1987; 25:361 Genomics 1990; 6:645 ref:Siracusa, Genomics 1990; 6:491 Cell 1980; 22:777 ref:Frankel, PNAS 1985; 82:6600 Mol Cell Biol 1983; 3:773 Leukemia 1990; 4:136 EMBO J 1987; 6:4041 EMBO J 1987; 6:4041 Cell 1984; 36:349 Cell 1984; 36:349 Cell 1986; 44:577 ref: Glaser, Genomics 1989; 5:510 Science 1990; 247:332 Oncogene 1988; 2:297 Cell 1986; 44:577 Oncogene 1988, 2:297 Cell 1986; 44:577 Oncogene 1988; 2:297 Cell 1986; 44",577 Oncogene 1988; 2:297 Cell 1986; 44:577 Biol Chem Hoppe-Seyler 1991; 372:301 Science 1986; 234:866 ref:Siracusa, Genomics 1990; 6:491 Nucl Add IRes 1986; 14:5111 PNAS 1983; 80.-3845 refiTaylor 1989; Cytogenet Cell Genet 52:102 DNA Cell Biol 1990; 9:487 ref:Bessis, FEBS Lett 1990; 264:48 J Mol Evol 1986; 23:11 Cell 1983; 30:185 ref:Minty, J Mol Biol 1983; 167:77 EMBO J 1986; 5:2559 Nature 1985; 314:181 EMBO J 1986; 5:2559 Biosd Rpt 1986; 6:741 EMBO J 1983; 2:1977 ref:Cresby, Genomics 1989; 5:19 ref:Siracusa, Genetics 1991; 128:813 Mol Cell Biol 1986; 6:4458 Somatic Cell Mol Genet 1989; 15:1 refiYeung, J Biol Chem 1985;260:10299 ref:Siracusa, Genetics 1989; 122:669 re~Glaser, Genomics 1989; 5:510 ref:Abbott, Biochem Genet 1991; 29:537 J Biol Chem 1985;260:10299 J Biol Chem 1985;260:10299 Genomics 1990; 7:476 ref:Aitman, M a m m Genome 1!}91; 1:206

co:Beaudet Daiger co: A T C C Jackson Surh Surh co:M Zuniga Robinson co:P Robinson

ref:Nakamura, Cytogen Cell Gen 1985; 40:710 Am J Hum Genet 1984; 36:736 ref: Siracusa, Genomics 1990; 6:491 Genomics 1990; 6:545 Gene 1991; 99:181 Gene 1991; 99:181 ref:Robinson, Immunogenetics 1984; 20:655 Immunogenetics 1984; 20:655 refiKnight, Mol Cell Probes 1990; 4:497

+

+ +

[V] XAM-I

+

Abl

Abelson murine leukemia oncogene

pK-2 IV] 1.9kb v-Abl flag [V] v-abl probe IV] kAb3, [V] pAB3Sub3 [V] pABSub3 pABlsub9

+ +

Abl cDNA-1,Abl eDNA-2 TS c-abl (testis specific) kabll, ~abl2, )~abl3 ~sbl4, ~abl5 pabl4.4 "

Acp-2 Acra

acid phosphatase-2 (lysosomal) acetylcholine receptor a

clone 108 genomic TypeI eDNA TypeI genomic TypeII eDNA TypelI genomic TypeIII eDNA TypeIII genornic TypelV eDNA TypelV me2 AChRal4-2

+

+ +

pA59 + +

Acra-4 Actc-1

acetylcholine receptor a4, neural actin, cardiac a

[R] HYA23-1E(1) pAF81

" Actc-1 probe LgA8,MG10 pmC1 [R] pCl8

Ada

adenosine deaminase

[R] pACT4.3 cGAM4.5, cGAM2.4 pAE 1.35, pAP 4.7 pADA5-29

+

+ + + +

+ +

+ + pADAS-43, pADAS-39 pADAS-23, pADA5-12 c2.5, c2.2, c3.5, c1.12, L7.1 MMADAP (microsat) + Akv-3 Ass-1

B2m

(withdrawn, see Emv-13) arginosuccinate synthetase-1

~-2 microglobulin

Refezencee

[H] pAS- i [I-I]pAS4/I/9 + pTZASMI2, p3C-eb2 + ~.113-22,~.I04-32,~.117-8, ;k34S, k42S, ~.102-30, ;~3C clone 23.2 KpnI-3.2kb + +

C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

318 Table 3. Continued.

Chr Symbda

2

B2m

LocusName

~-2 microglobulin (5' to coding sequence)

I~

KpnI-2.8kb frag of B2m cosmid I:~2-m2

RFLVe Coau~d

+ + + +

e~*2-ml, c~,2-m2 pB2m-1 pBI~B3 .

pBRcB4, Ch4A.B2-C57, Ch4A, B2-BALB B2m genomic + +

~2m (exon 1) (flank,exonI) ~2m (exon2)

pB2mX.dlII B2m cDNA-1 (probe A) flag o f B 2 m genomic-1 + pB2mdlII.B + +

2 2

Bdnf Bmi- 1

2

Bmp2a

2

Bmyc

2

Cas-1

~2m(exon2,intron) ~2m(intronI) ~2m(mutant clone) brain-derived neurotropic factor B lymphoma Mo-MLV insertion region 1

B2m cDNA-2 (probe B) B2m cDNA-3 (probe C) kB2bp3', %B2bp5' [H] BDNF ~.17,M3.5, probe b, probe d clones 2, 6, 15, 16, 26 clones 2.1, 19.1, 5.2, 13.1 bone morphogenetic protein 2a mBMP2a.9 + brain expressed myelocytomatosis oncogene [R] pRM44, [R] pRM05 [R] pRM13 catalase-1 [R] pMJS04 pmCAT-34 Cas-lg-PCR, Cas-la-PCR Cas-lb-PCR, Cas-la-PCR [H] CAT2-1 +

[H] ~ 2 4

§

[H] pMCT- I pCAT41 2

C f-2

coagulation factor II (prothrombin)

2

Chgb

chromogranin B

"D2H16" "D2H28" "D2H43" D2Hgul D2Lehl D2Leh2 "D2McCI" D2Mitl D2Mit2 DllS16h DllS408h DllS411h DllS412h Dlx-1 Emv-13

DNA segment, Chr 2, H16 cosmid DNA segment, Chr 2, H28 cosmid DNA segment, Chr 2, H43 cosmid DNA segment, Chr 2, Human Genetics Unit (Edinburgh)-i DNA segment, Chr 2, Lehrach-1 DNA segment, Chr 2, Lehrach-2 DNA segment, Chr 2, McClelland-1 DNA segment, Chr 2, MIT-1 (ex D11S14h) DNA segment, Chr 2, MIT-2 DNA segment, Chr 2, h u m a n D l l S 1 6 DNA segment, Chr 2, h u m a n DllS408 DNA segment, Chr 2, h u m a n DllS411 DNA segment, Chr 2, h u m a n DllS412 distal-less homolog endogenous ecotropic MuLV-13

MC1B, MII19, MII41, MII17B, MC20, MC3 CGB cDNA mcSgI-9c [R] Scg-1 cDNA Scg-1 2.3kb cDNA H16 H28 H43 [H] B6-6

+

+ +

+

PCR Line 6589 + PCR Line 6589 + AP-PCR oligo KB + [H] pDS1 + [H] po3.40-1 + [H] p32.1 + [H] pf3.6-3 + [H] pf8.10-3 + [H] pE2 + Dlx cDNA, Dlx genomic IV] pEnv + pEco pEe-B4 pEeo, pEc-B4 + p.Emv-13 N

+ +

2

Emv-15

endogenous ecotropic MuLV-15

Emv-13 genomic M29-AY pP0.5

+ + +

Robinson Stubbe co:Daniel,Kourilsky co:F Daniel co:Daniel,Kourilsky Rajan Parnes Meruelo Parnes Parnes co:JR Parnes co:D Margulies Potter Parnes co'A Seidman co:Rajan co:Rajan Parnes Parnes Parnes Ozcelik Haupt vanLohuizen vanLohuizen Wozney co:Wozney Ingvarsson lngvarsson co:Shaffer co:Shaffer ShatTer ShatTer vanHeyningen Siracusa co:GAP Bruns Quan co:R Korneluk Korneluk Degen Bremner Degen Degen Degen Linard Pohl Prochazka Jenkins Boyle Boyle Boyle Biekmore co:WA Biekmore Cox Cox co:M McClelland Glaser Glaser Glaser Glaser Glaser Giaser Price co:Jenkins Chattopadhyay Chan Taylor Copeland Copeland Siracusa co:NA J e n k i n s Siracusa Lovett Lovett

P~,~e e

Immunogenetics 1984; 20:655 Genomics 1990; 6:645 EMBO J 1983; 2:1061 ref: (]laser, Genomics 1989; 5:510 EMBO J 1983; 2:1061 J Immtmol 1990; 145:1598 PNAS 1981; 78:2253 Immunogenetics 1987; 25:361 Cell 1982; 29:661 Cell 1982; 29:661 ref:Carlsen, Mol Cell Biol 1988, 8:5528 ref:Adamsen, Virology 1991; 183:778 J Immunol 1987; 138:1270 EMBO J 1986; 5:103 ref:Frankel, PNAS 1985; 82:6600 ref:Siracusa, Genetics 1989; 122:669 ref:Dickinson, Genomics 1990; 6:505 EMBO J 1986; 5:103 EMBO J 1986; 5:103 EMBO J 1986; 5:103 Genomics 1991; 10:569 Cell 1991; 65:753 Cell 1991; 65:737 Cell 1991; 65:737 Science 1988; 242:1528 ref:Dickinson, Genomics 1990; 6:505 Mol Cell Biol 1988; 8:3168 Oncogene 1988; 3:679 J Biol Chem 1987; 262:12908 J Biol Chem 1987; 262:12908 Nucl Acid Res 1990; 18:4941 BBRC 1990, 173:1043 PNAS 1985; 82:6592 Genomice 1990; 6:491 ref:Glaser, Science 1990; 250:823 Nucl Acid Res 1986; 14:5321 ref:E1-Hage, Devel Genet 1990; 11:149 J Biol Chem 1984; 259:13819 DNA Cell Biol 1990; 9:487 Cell 1990; 61:407 DNA Cell Biol 1990; 9:487 DNA Cell Biol 1990; 9:487 DNA Cell Biol 1990; 9:487 Nuel Acid Res 1990; 18:1298 FEBS Lett 1990, 262:219 Mouse Genome 1991; 89:280 Genomics 1991; 11:479 Genomies 1992; 12:106 Genomics 1992; 12:106 Genornice 1992; 12:106 Nuel Acid Res 1988; 16:51 ref:Siraeusa, Genetics 1991; 128:813 Genomice 1991; 10:375 Genomics 1991; 10:375 ref:Welsh, Nucl Acid Res 1991; 19:5275 Science 1990; 250:823 Science 1990; 250:823 Science 1990; 250:823 Science 1990; 250:823 Science 1990; 250:823 Science 1990; 250:823 Nature 1991; 351:748 J Virol 1981; 43:26 PNAS 1980; 77:5774 PNAS 1980; 77:5579 Genomics 1989; 5:221 Cell 1983; 33:379 J Virol 1984; 49:437 Genetics 1989; 122:669 ref:Spence, Genomics 1992; 12:403 Genetics 1987; 117:85 PNAS 1987; 84:2853 Genetics 1987; 115:74 Continued on next p a g e

J.T. Eppig: Clones and Probes

319

Table 3. Continued. Chr Symbola

2

Emv-15

~

Name

Probeb

(3'unique)

p15.4

flank

15.4a pRI

RFLVc Contactd

+ + + + + + + + +

2

Emv- 15 Evx-1

(junction) even-skipped homeotic gene-1 homolog

2

Fshb

follicle stimulating hormone 13

2

Gad-1

Gcg

glutamie acid decarboxylase-1

glucagon

Ggta-1

a 1-3-galactosyltrans ferase

Glvr-1 Gnas

gibbon ape leukemia virus receptor-1 guanine nucleotide binding protein, a stimulating

Gsn

gelsolin hemolytic complement (C5)

pRI pLTR Evx-1 genomic, Evx-1 eDNA Evx-1 probe [H] pFSHB-1,4 [H] pRIM10 IF] sp65-GAD-16 MGADSA, MGAD33A clone 1AI IF] GAD cDNA

+ + +

+

[SHI pshil (or pshglul) + [B] 29-13A7 " + [R] pRGlul6 " + [B] clone 31A + pCDM7-aGT MGT-1, MGT~ MGT-7B, MGT-7C, Mgt-7D 4300-I + Gnas eDNA pGM13.1 [R] Gnas eDNA "

Hc

12A2B, 14A6A,Mu-319 pC5 + . pMC5.04 + + + + +

from H c 0 mice from H c I mice

pMCI04 cosl, cos4, cosl3 cosl3A, 13B, 13C, 13D, 13E coel3F + Hc 0 eDNA H e I eDNA [HI pHK24 + hck eDNA clone 9B 1 MK13, MK35, MK21, MK33 [R] HDC-2.3 + + L2.1 + His-1 probe + j S . j E jumping clone

1-Copeland Siracusa Siracusa Eieher Degen co:NA Jenkins Lovett Lovett co:M Lovett Carlson Lovett Bastian Bastian Bastian Watkins co:PC Watkins co:A Beck co:D Kaufman Brilliant co:Z Katarova Kaufman co:A Tobin Bell Lalley co:GI Bell Lopez co:Mock, Saunders Heinrieh co:G Heinrich Joziasse Joziasse Joziasse Joziasse co:CA Kozak Sullivan Ashley Jones Blatt Dieffenbach co:BF Tack Wetsel Wheat Wetsel co:Wetsel Birkenmeier Eicher co:BF Tack (Scripps) co:BF Tack co:RA Wetsel co:RA Wetsel co:RA Wetsel Wetsel Wetsel Ziegler co:Perlmutter Holtzman Lock Ziegler Joseph co:DJoseph co:JN Ihle co:DS Askew,JN Ihle Stub~

Hck- 1

hemopoietic cell kinase-1

Hdc

histidine decarboxylase cluster

His-1

hematopoetic insertion site-1

Hox-4

homeo box-4 cluster

~d~e A, ~obe B

St~t~

Hox-4.1

homeo box-4 duster, gene 1

Hox-4.1 genomic Ch23 (mh23)

Hoxo4.2

homeo boxo4 duster, gene 2

Hox-4.2 eDNA " (5' frag) Hox-4.2 genomic pGEM160 cos E, cos 64, cos N cos E Hox-4.3 cDNA, Hox-4.2 genomic done 49h

Dolle Lonai Stuh~ Featherstone Stub~ Featherstone Siracusa Duboule Stubbs co:D Duboule co:D Duboule Singh

Hox-4.3

homeo box-4 cluster, gene 3

+ +

+

Refe~axme

ref.'Siracusa, Genetics 1987; 117:85 Genetics 1987; 117:93 Genetics 1989; 122:669 Genetics 1990; 125:431 DNA Cell Biol 1990; 9:487 ref:Spence, Genomics 1992; 12:403 PNAS 1987; 84:2853 Genetics 1987; 115:747 ref:Glaser, Genomics 1989; 5:510 Mol Cell Biol 1988; 8:5528 PNAS 1987; 84:2853 EMBO J 1990; 9:1839 EMBO J 1990; 9:1839 EMBO J 1990; 9:1839 DNA 1987; 6:205 ref:Siracusa, Genomics 1990; 6:491 ref:Glaser, Science 1990; 250:823 ref:Brilliant, Genomics 1990; 6:115 Genomics 1990; 6:115 ref:Brilliant, Genomics 1990; 6:115 Science 1986; 232:1138 ref:Hess, Neuron 1991; 6:123 Nature 1983; 302:716 Cytogenet Cell Genet 1987; 44:92 ref:Zahedi, J Immunol 1991; 146:4228 PNAS 1983; 80:5485 ref:Siracusa, Genomics 1990; 6:491 Endocrinology 1984; 115:2176 ref: Glaser, Genomics 1989; 5:510 Sore Cell Mol Genet 1991; 17:201 J Bid Chem 1992; 267:5534 J Biol Chem 1992; 267:5534 d Biol Chem 1992; 267:5534 ref:Adamson, Virology 1991; 183:778 PNAS 1986; 83:6687 d Biol Chem 1987; 262:15299 d Biol Chem 1987; 262:14241 PNAS 1988; 85:7642 J Bid Chem 1989; 264:13281 ref:D'Eustachio, d Immunol 1986; 137:3990 Complement 1985; 2:86 d Exp Med 1987; 165:1442 Biochemistry 1987; 26:737 ref:Moen, Mamm Genome 1991; 1:217 PNAS 1988; 85:8121 Genetics 1990; 125:431 ref:Siraeusa, Genomics 1990; 6:491 Jozia~e, Sore Cell Mol Genet 1991; 17:201 ref:Haviland, J Biol Chem 1991; 266:11818 ref:Haviland, J Biol Chem 1991; 266:11818 ref:Haviland, J Biol Chem 1991; 266:11818 J Biol Chem 1990; 265:2435 J Biol Chem 1990; 265:2435 Mol Cell Biol 1987; 7:2276 ref:Siraeusa, Genetics 1989; 122:669 PNAS 1987; 84:8325 Mol Cell Biol 1990; 10:4603 Oncogene 1991; 6:283 PNAS 1990; 87:733 ref:Adamson, Virology 1991; 183:778 ref:Askew, Oncogene 1991; 6:2041 ref: Siracusa, Genetics 1991; 128:813 Genomies 1990; 7:422 Genomics 1990; 7:422 Nature 1989; 342:767 DNA 1987; 6:409 Genomics 1990; 7:422 P N A S 1988; 85:4760 Genomies 1990; 6:645 PNAS 1988; 85:4760 Genomics 1990; 6:491 EMBO J 1989; 8:1497 Genomics 1990; 7:422 ref:Izpisua-Belmonte, Develp 1990;110:733 rof:Izpisua-Belmonte, Develp 1990;110:733 PNAS 1991; 88:10706 Continued on next page

320

J.T. Eppig: Clones and Probes

Table 3. Continued. Chr Symt~a

2

Hox-4.4

Loc~ Name

homeo box-4 duster, gene 4

Probeb

RFLVc Conl~dcl

ces N, cos H

+

Duboule Dolle Duboule Dolle co:R Krumlauf Moore Lomedico co:Lomedico

+ + +

co:Young co:Young co:SB Mizel

"

2 2 2 2 2

Hox-4.5 Hox-4.7 Hox-4.9 Hsp84-2 II-la

homeo box-4 duster, gene 5 homeo box-4 duster, gene 7 borneo box-4, gene 9 heat shock protein 84kDa-2 interleukin-la

cos N, cos H Hox-4.7 genomic Hox-4.9 eDNA done A, clone B piLl-1301, piLl-31 piLl-1301

pMuIL-la + a- 1.3.2 a-RCF1 II-la cDNA 2

II-lb

interleukin- 1~

pMuIL-l~ + II-lb genomic II-lb eDNA

2

Illrn

interleuin-1 receptor antagonist

2

I12ra

interleukin-2 receptor, a chain

~-7.1 MMIL1BG (microsat) MMIL1AG (microsat) MI1 Illrn cDNA rolL 1Ra cDNA Illrn genomic pcEXV-MIL2R8

+ + +

[p~ subunit] ll2ra probe mIL-2R 8 clone eDNA clones A through L Jgf-1 eDNA + ~.KIN17 pKGC101

2 2

JgS1 "Kin"

anonymous mouse cDNA antigenic determinant of recA protein

2

Kras-3

Kirsten rat sarcoma oncogene-3

pswz1-1

2

ld

limb deformity (wild type)

2

Ltk

leukocyte tyrosine kinase

2

Ly-24

lymphocyte antigen-24 (Pgp-1)

probes A,B,C, IdHdcosmid 0.Tkb probe clones 1,2, 3, 4, 5, 6, 7, clones 8, 9, 10 BP1.7 + pRK14 + M M 100, Ly-24 e D N A

+

2

"Mns-2"

2

Mpmv-3

2 2

2 2 2 2 2 2 2 2 2 2 2 2 2 2 2 2

minor satellite Chr 2 (centromeric)

mLHR clones MHR6, MHR13 mLHRc eDNA Pgp-1 eDNA pMR150 "

modified polytropic murine leukemia virus-3 JS-4 JS-4 Mpmv-14 modified polytropic murine leukemia virus-14 JS-4 Mpmv-28 modified polytropic murine leukemia virus-28 JS-4 JS-4 JH "Msl-I-3-P2" mlnisatellite 1-1-3-P2 (Drosophila Per) pSP.2.5.EI "Msl-I-5-PI" minisatellite 1-1-5-P1 (Drosophila Per) pSP.2.5.EI "Msl-2-17-P2" minisatellite 1-2-17-P2 (Drosophila Per) pSP.2.5.EI "Msl-2-18-P2" minisatellite 1-2-18-1)2 (Drosophila Per) pSP.2.5.EI "Msl-2-19-PI" minisatellite 1-2-19-P1 (Drosophila Per) pSP.2.5.EI "Msl-3-3-P2" minisatellite 1-3-3-P2 (Drosophila Per) pSP.2.5.EI "Msl-3-7-PI" minisatellite 1-3-7-P1 (Drosophila Per) pSP.2.5.EI "Ms2-1-4r minisatellite 2-1-4-P2 (human D1S57) pYNZ2 "Ms2-3-2-P2" minisatellite 2-3-2-1)2 (human D1S57) pYNZ2 "Ms2-3-6-Pl" minisatellite 2-3-6-P1 (human D1S57) pYNZ2 "Ms3-3-4-Pl" minisatellite 3-3-4-P1 (human D3S45) pEFD134.7 ~Ms3-1-6-PI" minisatellite 3-1-6-P1 (human D3S45) pEFD134.7 "Ms3-2-15-Pl" minisatellite 3-2-15-P1 (human D3S45) pEFD134.7 ~Ms3-3-6-P2" minisatellite 3-3-6-P2 (human D3S45) pEFD134.7 ~Is3-3-7-Pl" minisatellite 3-3-7-P1 (human D3S45) pEFD134.7 "MsS-I-I-P2" minisatenite 5 -l-l-P2 pEWRB2.3

+ + + + + + + + + + + + + + + + + + + + +

Referencee

E M B O J 1989; 8:1497 E M B O J 1989; 8:1507 E M B O J 1989; 8:1497 Nature 1989, 342:767 ref:Hunt, Nature 1991; 353:861 Gene 1987; 56:29 Nature 1984; 312:458 ref:Carlson, Mol Cell Biol 1988; 8:5528 ref:Siracusa, Genetics 1989; 122:669 ref:Dickinson, Genornics 1990; 6:505 ref:Zahedi, J Immunol 1991; 146:4228 J Immunol 1986; 137:3644 Immunogenetics 1987; 26:339

Gray D'Eustachio D'Eustachio Immunogenetics 1987; 26:339 Immunogenetics 1987; 26:339 D'Eustachio co:AR Shaw (Glaxco) ref:Boultwood, Genomics 1989; 5:481 co:AR Shaw (Glaxco) ref:Silver, Sore Cell Mol Genet 1990; 16:549 J Immunol 1986; 137:3644 Gray D'Eustachio Irnmunogenetics 1987; 26:339 Telford Nucl Acid Res 1986; 14:9955 co:AR Shaw (Glaxco) ref:Boultwood, Genomies 1989; 5:461 co:AR Shaw (Glaxco) ref:Silver, Sore Cell Mol Genet 1990; 16:549 D'Eustachio Immunogenet 1987; 26:339 Montegutelli Mamm Genome 1991; 1:255 Montagutelli Mamm Genome 1991; 1:255 co:AS Whitehead ref:Zahedi, J Immunol 1991; 146:4228 co:CJ Sherr ref:Matsushime, Blood 1991; 78:616 co:MJ Bienkowski ref:Shuck, Eur J Immunol 1991; 21:2775 Eisenberg PNAS 1991; 88:5232 Miller J Irnmunol 1985; 134:4212 co:RN Germain refiWebb, Cytogenet Cell Genet 1990; 54:164 co:IG Young refiWebb, Cytogenet Cell Genet 1990; 54:164 co:J Miller, R Germain refiFroussard, J Immunol 1988; 141:1358 co:J Miller, R Germain ref:Frousaard, J Immunol 1988; 141:1358 co:Radice(Columbia) ref:Siracusa, Genomics 1990; 6:491 co:R Devoret reflAngulo, Biochimie 1991; 73:251 co:R Devorot ref:Angulo, Nucl Acid Rcs 1991; 19:5117 McCoy Mol Cell Biol 1984; 4:1577 co:ATCC reflSiracusa, Genomics 1990; 6:491 + Woychik Nattme 1985; 318:36 Woychik PNAS 1990; 87:2588 Woychik Nature 1990; 346:6287 Woychik Nature 1990; 346:6287 co:Woychik ref.'Glaser, Science 1990; 250:823 Ben-Neriah Nature 1988; 333:672 Siracusa Genomics 1990; 6:491 Nottenburg PNAS1989; 86:8521 Lasky Cell 1989, 56:1045 Zhou J Immunology 1989; 143:3390 Siegelman Science 1989; 243:1165 Wolffe J Biol Chem 1990, 265:341 Voliva Nucl Acid Res 1983; 11:8847 co:VM Chapman tel:Broccoli,Cytogenet Cell Genet 1990; 54:182 co:ND Hastie ref:Pietras,Nucl Acid Res 1983; 11:6965 Frankel Genetics 1990; 124:221 Frankel Mamm Genome 1992; 2:110 Frankel Genetics 1990; 124:221 Frankel Genetics 1990; 124:221 Frankel Mamm Genome 1992; 2:110 ref:Gerstein, Cell 1990; 63:537 co:W Frankel Juliet PNAS 1990; 87:4585 PNAS 1990; 87:4585 Julier Julier PNAS 1990; 87:4585 PNAS 1990; 87:4585 Julier Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS1990; 87:4585 Juliet PNAS1990; 87:4585 Juliet PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Continued on next page

321

J.T. Eppig: Clones and Probes Table 3.

Continued.

Symbda

2 2 2 2 2 2 2 2 2 2 2 2 2

Locus Name

Probeb

RFLV: Contac~

"Ms5-2-8-P2" minisatellite 5 -2-8-P2 pEWRB2.3 "Ms5-2-9-Pl" minisatellite 5 -2-9-P1 pEWRB2.3 'WIs5-3-4-P2" minisatellite 5 -3-4-P2 pEWRB2.3 "Ms6-1-6-P2" minisatellite 6-1-6-P2 (human D14S1) pAWl01 "Ms6-1-7-PI" minisatellite 6-1-7-P1 (human D14S1) pAWl01 '2~IsS-2-1-Pl" minisatellite 8-2-1-P1 (human INS) pINS310 "Ms8-3-2-P2" minisatellite 8-3-2-P2 (human INS) pINS310 '2~IsS-2-2-P2" minisatellite 8-2-2-P2 (human INS) pINS310 '2Ylsll-l-l-Pl" minisatellite l l - I - I - P I (human D17S24) pRMU3 "Msll-2-4-Pl" minisatellite 11-2-4-P1 (human D17S24) pRMU3 "Msll-2-6-P2" minisatellite 11-2-6-P2 (human D17S24) pRMU3 ~Msll-I-3-P2" minisatellite 11-1-3-P2 (human D17S24) pRMU3 Mtv-40 m a m m a r y tumor virus locus-40 MMTV8-21 (called Mtv-30 in reference) Neb nebulin [H] pHNNS4.3

+ + + + + + + + + + + + +

+ + + 4-

2 2

"Nkx-2.2" homolog of Drosophila NK-2 Odc-rs2 ornithine decarboxylase related seq-2

Nk-2.2 genomic pCR6 (pDOC934 derived)

2 2

Otf3-rs2 Pax-1

5' Off-3 cDNA Pax-1 genomic

+

Otf-3 related sequence-2 paired box homeotic gene-1

+ +

Pax-1 genomic (PCR) Pax-1 cDNA Pax- 1/PCR-3' pSM-1, Pax-6 PCR ~ 4 , cpSnl, ~ 1 , c~11 c980, c2A, c3B, e27B, Pax-8 genomic pPCK10 [R] pPCK10

2

Pax-6

paired box homeotic gene-6

2

Pax-8

paired box homeotic gene-8

2

Pck-1

phosphoenolpyruvate carboxykinase- 1, cytosolic

2 2 2

Phpp-2 Pmv-7 Pmv-33

prehormone processing proteinase (Kex2 homology) mPC2 polytropic murine leukemia virus-7 JS-5 polytropic murine leukemia virus-33 JS-5

2 2

Pol-23 Prn-p

viral polymerase-23 prion protein, structural

+ + + + +

+

+ + +

B65.5PV2 derivative clone 9

+ + §

clone 9, clone 7 Prn eDNA + subclone 9, subclone 13 + [Ha] pHaPrP + +

2

Psp

parotid secretory protein

2

Ptpa

protein t y r ~ i n e phosphatase a

2

Pygb

brain glycogen phosphorylase

2

Rag-1

recombination activating gene-1

2 2

Rag-2 recombination activating gene-2 Rnu3b-ps2 U3B small nuclear RNA pseudogene 2

5' UT probe + [Ha] pl.40 + [Ha] pl.40 + [H] pmPrP3 + Prn-p genomic- 1 Prn-p genomic-2 Prn-p genomic-3 Prn-p genomic-4 pMPdl6, pMpd39, pMPd 12 ~,PSPI + Psp cosmid + HhaI-Psp probe 4-

~,109 p109, p923 [R] B-GPI

+ 4-

M6, R7.5, 8B12, 9U.3, 9F.2, 10E.1,15B14, 12C.2 MR1-C + 12C.2, M6 12C.2, MR2-1 pP~3B.15 probe P, p r e ~ U

Refenmcee

Julier Juliet Julier Julier Julier co:G Bell co:G Bell co:G Bell Julier Julier Julier Julier co:JE Majors

PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 ref:Siracusa, Genetics 1991; 127:169

Zeviani Mock co:EA Schon eo:P Gros co:B Mock, EA Schon Price Rheaume co:FG Berger Siracusa Deutsch Balling co:Deutsch seq Dressler Abbott Hill Walther Plachov Plachov co:Lem Yoo-Warren co:Hanson Seidah Frankel Frankel Frankel Rossomando co:B Cheseboro co:B Cheseboro Westaway Locht Race co:B Cheseboro co:B Oesch co:B Oesch Oesch Carlson co:G Carlson co:(] Carlson co:C Puckett Westaway Westaway Westaway Westaway Madsen Shaw Barsh Barsh Shaw co:Shaw Sap Sap Crerar Glaser Schatz Schatz co:D Baltimore Oettinger Oettinger Mazan

Genomics 1988; 2:249 Genomics 1990; 7:57 ref:Schurr, Genomics 1990; 8:477 refiSchurr, Genomics 1991; 57:214 ref:Siracusa, Genetics 1991; ].28:813 Neuron 1992; 8:241 Mol Endocrinol 1989; 3:1243 ref:Siracusa, Genetics 1991; 127:169 Genomics 1991; 10:313 Cell 1988; 53:617 Cell 1988; 55:531 ref:Siracusa, Genomics 1990; 6:491 Development 1988; 104 (supp):181 Mouse Genome 1992; 90:86 Nature 1991; 354:522 Development 1991; 113:1435 Development 1990; 110:643 Development 1990; 110:643 Somatic Cell Mol Genet 1985; 11:633 PNAS 1983; 80:3656 ref:Siracusa, Genetics 1989; 122:669 DNA Cell Biol 1990; 9:415 J Virol 1989; 63:3810 J Virol 1989; 63:3810 M a m m Genome 1992; 2:110 Immunogenetics 1986; 23:233 Nature 1985; 315:331 ref:Race, J Gen Virol 1990; 71:493 Cell 1987; 51.~51 PNAS 1986; 83:6372 J Gen Virol 1990;, 71:493 ref.'Carlson, Mol Cell Biol 1988, 8:5528 ref:Carlson, Mol Cell Biol 1988, 8:5528 refiCarlson, Cell 1986; 46:503 Cell 1985; 40:735 Mol Cell Biol 1988; 8:5528 ref:Siracusa, Genomics 1990; 6:491 refiDickinson, Genomics 1990; 6:505 ref: Glaser, Genomics 1989; 5:510 Cell 1987; 51.~L51 Cell 1987; 51:651 Cell 1987; 51.%51 Cell 1987; 51.%51 Nucl Acid Res 1985; 13:1 J Mol Biol 1986; 192:557 Genomics 1989; 5:9 Genomics 1989; 5:9 J Mol Biol 1986; 192:567 ref:Siracusa, Genetics 1989; 122:669 PNAS 1990; 87:6112 PNAS 1990; 87:6112 Genome 1988; 30:582 Genomics 1989; 5:510 Cell 1989; 59:1035 Cell 1989;, 59:1035 reflOettinger, Immunogenetics 1992; 35:97 Science 1990; 248:1517 Science 1990; 248:1517 E u r J Biochem 1989; 181:599 Cytogenet Cell Genet 1991; 58:18

Mazan

C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

322 Table 3. Continued. Symb~a

Iz~us Name

P~e b

2

Rpl7

Ribosomal protein L7 (ex Surf-3)

2

Rpn-2

(7 kb upstream probe) ribophorin II

Surf-3 eDNA MY3 19kb EcoRI X clone L7-16b D16 Surf-3 genomie [H] Rpn-2 eDNA

2

"S8"

$8 protein (homeobex related)

S8 eDNA

2 2

Sey Sfpi-1

small eye (see Pax-6) SFFV provira] integration-1

2

Sgne- 1

2

Spna-2

SSE, $8 genomic

Src

Surf

Surf-1 Surf-2

Surf-3 Surf-4

Surf-5 Surf-6 Svp-1 Thbs- 1 Vim

Wt-1 Xmv-10 Xmv-48 Acrb-2 Acts

Adh-1

R~LVc Contactd

+

Giallongo Williams Huxley Meyuhas coil Pike Stubbs Barton Crimaudo Kongsuwan co:J Adams co:F Meijlink

probe B Moreau-Gachelin clones G49,F38,F6,E4a,bl,b8 Moreau-Gachelin secretory granule neuroendocrine protein-1 7B2 eDNA Mbikay Mattei a-spectrin-2, brain (fodrin) [C] pUCS-13a + Birkenmeier + Birkenmeier [C] NESPNA-1 + co:CS Birkenmeier JR] RBF2 Barton Lete + eo:Leto (NIA1D: Rous sarcoma oncogene v-sate + co:Simon pSRA2 (%.SRA2) DeLorbe co:WJ DeLorbe + co:WJ DeLorbe pN1.8 Martinez + co:Martinez pMI/Xba + eo:N Quintrell clone 54 Dymecki surfeit gene d u s t e r Chl-49, Ch16-49, Ch31-49, Klein Ch18-49, Ch36-49, Ch28-49, Klein Ch35-49, Ch46-49, Ch16b-49 Klein Surf-l, -2, -5, -6, Rpl7 19kb EcoRI k clone Huxley Surf-2, -4 14kb BamHI ~. clone Huxley surfeit gene-1 T2A, T1B, IDE Williams 19kb EcoRI ~. clone Huxley surfeit gene-2 H1, T3C, J3 Willis ms 19kb EcoRI ), clone Huxley 14kb BamHI ~. clone Huxley (withdrawn, see Rpl7) surfeit gene-4 RMC4 Williams eDNA 15 Huxley 14kb BamHI X clone Huxley 15kb BClI X clone Huxley surfeit gene-5 19kb EcoRI ~ clone Huxley surfeit gene-6 19kb EcoRI k clone Huxley seminal vesicle protein-1 pSV-008 Esworthy + co:Esworthy thrombospondin-1 [H] pTS33 Jaffe ~42 Borustein mTSP1 eDNA . co:VM Dbdt vimentin pMV62 Capetanaki IH] Vim eDNA Matted VIM3, VIMS, clone 2/2 Hennekes [H] cHu-Viml Perreau + co:ATCC Wilms tumor homolog [H] pk13.28-1 + Glaser [HI po3.40-1 + Glaser xenotropic murine leukemia virus-10 JS-6+JS-10 + Frankel JS-6+JS-10 + Frankel xenotropic murine leukemia virus-48 JS-6+JS-10, XENOll2 + Frankel acetylcholine receptor ~2, neural JR] PCX49(1) + co:J Boulter (Salk) actin, skeletal a proS1, proS2, proS4 Leader pAM91 + co:Buckingham Alonso Acts probe + Robert JR] p749 Katcoff Czosnek [R] pAcl5-2, Act15 Nudel " Czosnek Acts exon 1-3 + co:N Davidson alcohol dehydrogenase-1 complex pHJE-mYAI,pHJE-mYA2 Z h a n g Adh-1 genomic Zhang Adh-1 cDNA + Zhang Adh-1 microsat + co:Zhang pADHmg, pADHml2 Ceci

Referencee

Mol Cell Biol 1989; 9:224 PNAS 1988; 85:3527 Mol Cell Biol 1990; 10:605 J Biol Chem 1990; 265:11465 tel:Taylor, Mol Reprod Devel 1992; 31:182 Genomics 1990; 6:645 Cytogenet Cell Genet 1987; 46:577 EMBO J 1987; 6:75 EMBO J 1988; 7:2131 refiOpstelten, Mech of Devel 1991; 34:29 refiOpstelten, Mech of Devel 1991; 34:29 Nature 1988; 331:277 Oncogene 1989; 4:1449 Int J Peptide Protein R ~ 1989; 33:39 Genomics 1990; 6:436 PNAS 1985; 82:5671 PNAS 1988; 85:8121 refiZahedi, J Immunol 1991; 146:4228 Cytogenet Cell Genet 1987; 46:578 Mol Cell Bioi 1988; 8:1 ref:Siracusa, Genomics 1990; 6:491 ref:Blatt, Mol Cell Biol 1984; 4:978 J Virel 1980; 36:50 ref:Sakaguchi, PNAS 1984; 81:525 refi Blatt, Mol Cell Biol 1984; 4:978 Science 1987; 237:411 ref:Siracusa, Genetics 1989; 122:669 ref.'Glaser, Genon~cs 1989; 5:510 Science 1990; 247:332 Nucl Acid ires 1984; 12:3763 N u d Acid Res 1984; 12:3763 Nucl Acid Res 1984; 12:3763 Mol Cell Biol 1990; 10:605 Mol Cell Biol 1990; 10:605 Mol Cell Biol 1986; 6:4558 Mol Cell Biol 1990; 10:605 Mol Cell Biol 1986; 6:4558 Mol Cell Biol 1990; 10:605 Mol Cell Biol 1990; 10:605 PNAS 1988; 85:3527 Mol Cell Biol 1990; 10:605 Mol Cell Biol 1990; 10:605 Mol Cell Biol 1990; 10:605 Mol Cell Biol 1990; 10:605 Mol Cell Biol 1990; 10:605 Mouse News Lett 1986; 64:90 ref:Siracusa, Genetics 1989; 122:669 Genomics 1990; 7:123 J Biol Chem 1990; 265:16691 ref:Laherty, J Biol Chem 1992; 267:3274 Oncogene 1990; 5:645 Genet Res 1989; 53:183 Mol Gen Genet 1990; 221:33 Gene 1988; 62:7 ref:Siracusa, Genomics 1991; 10:313 Science 1990; 250:823 Science 1990; 250:823 J Virol 1989; 63:1763 M a m m Genome 1992; 2:110 M a m m Genome 1992; 2:110 ref:Bessis, FEBS Lett 1990; 264:48 DNA 1986; 5:235 ref:Minty, J Mol Biol 1983; 167:77 J Mol Evol 1986; 23:11 Nature 1985; 314:181 PNAS 1980; 77:960 EMBOJ 1982; 1:1299 PNAS 1982; 79:2763 EMBOJ 1982; 1:1299 ref:Seldin, Nucl Acid Res 1987; 15:1881 Gene 1987; 57:27 Gene 1987; 57:27 Gene 1987; 57:27 ref:Hearne, M a m m Genome 1991; 1:273 Gene 1986; 41:217 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

323

Table 3. Continued. Chr S y m ~ a

3

Adh-1

Ix~us Name

alcohol dehydrogenase-1 complex

Probeb

RFLVc ~ a c t d

LADH22, LADH18 phDHg18-1

pZK105-36,

+ + + +

3 3

Adh-lps Ampd-1

alcohol dehydrogenase-1 pseudogene AMP deaminase-1

pZK6-6, pZK7 pZK102-21, pZKl12-72 pADHml6 [R] Ampd-1 eDNA

3 3

Ampd-2 Amy-1

AMP deaminase-2 amylase-l, salivary

[R] Ampd-2 eDNA pMSal04

4-

+ + + +

3 3 3 3 3 3 3

eSam47, cSamJ4, eSamJ8 AMY-1 microsat + Amy-l(p) amylase-l, 5' flank promoter, noncoding cSamD4 + phage 1, 2, 3, 4, 5, 6, 7, 8, 9 Amy- 1(5') amylase-i, 5' te the gene Amy-1 a amylase-l, allele a phage 10, 11, 12, 13, 14, 15 phage ]6, 17, 18, 19, 20 Amy-l.1 anaylase- 1 (YBR) SD8-3 Amy-l.2 amylase-1 (YBR) SF9-5, SE7-3, SE10-5, SB5-1, SF1-2, SE1-3 Amy-l, Amy-2 intergenic region phage 21 Amy-2 amylase-2, pancreatic pMPa21 + +

pmbe3 + +

3

Amy-2 a l Amy-2 a n

amylase-2, allele a l amylase-2, allele an

3

Amy-2.1

amylase-2, pancreatic

3

Amy-2.2

amylase-2 pancreatic

3

Ank-2

ankyrin-2 (brain specific)

3

Ap2

adipocyte specific protein aP2

cSarnJ8, cPamE1 phage 22, 23, 24 phage 25, 26, 27, 28, 29, 30 phage 31, 32 cPamE 1 pADPal,pADPa2,pADPa3 cPam23, cPam24 pADPbl, pADPb2, pADPb3, pADPb4 [H] hBrank-2 +

3 3

Arnt Atplal

paP2 Ap2 cDNA MMLBPA (microsat) (miemsat) aryl hydrocarbon receptor nuclear translocator Arnt cDNA ATPase, Na+K +, a l polpeptide [RI rb5 [H] ATP1A2 eDNA [R] z4a

+ + + + + +

3

Bglap

3

Cacy

pRLouaR-8 MaG-9, MAC-6 MaG-6 bone Tcarboxyglutamate prot (osteoealcin) bone gla clone [R] pR22-11 caleyclin [HI hp2A9 frag + +

3 3 3

Calll Capl Car-1

ealpaetin I light chain calcium binding protein, placental carbonic anhydrase-1

3

Car-2

carbonic anhydrase-2

5131O 1/325 p l l eDNA + 18A2 + pMCAI kCAI-4,~.CAI- 12,7~CA1-21 pMCAII (= p6-69) + +

(from YBR)

cosMCAII-2 pMCAII-7.2

+

Ceei Ceci Edenberg Edenberg Edenberg Ceci Kingsmore Kingsmore Moseley 1-Wellauer 1-Paul,Elliott Hagenbuchle Blatt co:Hagenbuchle Wiebauer co:Meisler Wiebauer Meisler Pittet Pittet Pittet Jones Jones Jones Pittet co:Wellauer Thomsen co:Paul,Elliott Hagenbuchle co:Hagenbuchle co:Wellauer Gumucio Moseley Kingsmore Wiebauer Pittet Pittet Pittet Meisler Meisler Meisler Meisler Meisler Otto co:EM Otto Hunt co:B Spiegelman co:JA Todd co:JA Todd Hankinson co:Levenson co:Dackowski Kent co:R Levenson co:R Levenson Levenson Tam co:D Housman Celeste co:JM Wozney Ferrari co:R Baserga co:R Baserga Guo Poirier Saris co:D Linzer Fraser Fraser co:PJ Curtis co:PJ Curtis co:PJ Curtis co:TR Bishop Venta Vents

l~eferen~

Gene 1987; 59:171 Gene 1987; 5~,171 PNAS 1985; 82:2262 PNAS 1985; 82:2262 PNAS 1985; 82:2262 Gene 1987; 5~.171 Genomics 1990; 6:482 Genomies 1990; 7:75 Genomics 1990; 6:572 ref:Schibler, J Mol Biol 1980; 142:93 Biochem Genet 1987; 25:569 Cell 1980; 21:179 Somatic Cell Mol Genet 1988; 14:133 ref:Meisler, Genetics 1986; 113:713 PNAS 1985; 82:5446 ref:Hearne, Marnm Genome 1991; 1:273 PNAS 1985; 82:5446 Genetics 1986; 113:713 J Mol Biol 1985; 182:359 J Mol Biol 1985; 182:359 J Mol Biol 1985; 182:359 Nucl Acid Res 1989; 17:6613 Nucl Acid Res 1989; 17:6613 Nucl Acid Res 1989; 17:6613 J Mol Biol 1985; 182:359 ref:Schibler, J Mol Biol 1980; 142:93 Biochem Genet 1984; 22:257 Biochem Genet 1987; 25:569 Cell 1980; 21:179 ref:Meisler, Genetics 1986; 113:713 ref:Schibler, J Mol Biol 1980; 142:93 J Biol Chem 1985; 260:13483 Genomics 1989; 5:899 Genomics 1990; 7:75 PNAS 1985; 82:5446 J Mol Biol 1985; 182:359 J Mol Biol 1985; 182:359 J Mol Biol 1985; 182:359 ref.'Gumucio, J Biol Chem 1985; 260:13483 ref:Gumucio, J Biol Chem 1985; 260:13483 ref:Gumucio, J Biol Chem 1985; 260:13483 refiGumucio, J Biol Chem 1985; 260:13483 refiGumucio, J Biol Chem 1985; 260:13483 J Cell Biol 1991; 114:241 ref:Peters, J Cell Biol 1991; 114:1233 PNAS 1986; 83:3786 rel~Heuckeroth, J Biol Chem 1987; 262:9709 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 Biochimie 1991; 73:61 ref:Kent, PNAS 1987; 84:5369 ref:Wong, J Exp Med 1990; 171:2115 PNAS 1987; 84:5369 ref:Moseley, Genomics 1989; 5:899 ref:Kingsmore, Genomics 1990; 7:75 PNAS 1984; 81:1489 Mol Cell Biol 1990; 10:6619 ref:Boyle, PNAS 1990; 87:7757 EMBO J 1986; 5:1885 ref:Johnson, Genomics 11:770 J Biol Chem 1987; 262:8325 ref:Moseley, Genomics 1989; 5:899 ref:Kingemore, Genomics 1990; 7:75 Cell Growth Devel 1990; 1:333 Development 1991; 113:1105 J Biol Chem 1987; 262:10663 ref:vanHeyningen,Cyto Cell Gen 1989;51:1095 J Mol Evol 1986; 23:294 Mol Cell Biol 1989; 9:3308 Curtis, Gene 1983; 25:325 J Biol Chem 1983; 258:4459 ref:Moseley, Genomics 1989; 5:899 retIPNAS 1986; 83:5568 J Biol Chem 1985; 260:12130 J Biol Chem 1985; 260:12130 C o n t i n u e d on next p a g e

324

J.T. Eppig: Clones and Probes

Table 3. Continued, Chr ~ a

Locus Name

3

Car-3

carbonic anhydrase-3

3

Cf-3

coagulation factor III

3

Cnp-2

cyclic nucleotide phosphodiesterase-2

3

Csfm

colony stimulating factor, macrophage

3 3

"D3H44" D3Jfrl

3 3 3 3

osteopetrosis (op) mutation (at Csfm) DNA segment, Chr 3, H44cosmid DNA segment, Chr 3, MJeffers-1 (5' upstream o f N r a s gene) D3Lehl DNA segment, Chr 3, Lehrach-1 D3Leh2 DNA segment, Chr 3, Lehrach-2 "D3McCI" DNA segment, Chr 3, McClelland-1 Egf epidermal growth factor

3

Emv-27

endogenous ecotropic MuLV-27

3

Evi-1

ecotropic viral integration site-1

3

Evi-1

ecotropic viral integration site-1 5' to Evi-1 5' to Evi-1 3' to Evi-1

Fabpi

fatty acid binding protein intestinal

Fgf-2

fibroblast growth factor-2 (basic)

Fgg

g a m m a fibrinogen

Fire-3

Friend MuLV integration site-3

Fth-rsl Gba

5' and 3' clones to Fim-3 ferritin, heavy chain related sequence 1 glucosidase, beta, acid glutaminase

Gbp- 1 Glut-2

guanylate nucleotide binding protein-1 glucose transporter protein-2, liver

Hist2

histone gene complex-2 (H2a,H3) (H3.2) (H2a.2)

Probeb

pCAIIIM.7

RFLVc Contat~d

+ +

Tweedie Beechey eDNA clone 482 Hartzell IgMTF2282, pcMTF2253 Mackman pcMTF2261 + Mackman Cnp cDNAII Kurihara [R] pCNP-2 + Bernier M-CSF-cDNA + co:A Belt Csfm eDNA Rajavashisth Csfm eDNA- 1 DeLamarter cCSF-10 co:E Kawasaki Csfm genomic-1, -2 Baurnbach pUS-1 Baumbach + Buchberg 4kb-cDNA, 2kb-cDNA Ladner [H] cCSF-17 Kawasaki [H] 3ACSF-69 Wong pBSST2 Yoshida pBSol>l Yoshida H44 Boyle [R] 1.5kb u n r eDNA Jeffers [R] 2.5kb u n r eDNA Jeffers PCR Line 6589 + Cox modified B2 SINE + Cox AP-PCR oligo KA+KB + co:M McClelland pmegfl0,pmegfl0b,pmegfl Scott pmegf44,pmegf39,pmegf35 Scott pmegfl0 + co:Rutter Zabel + co:GI Bell pEco Chattopadhyay pEc-B4 Chan pEco, pEc-B4 + Taylor pEco Chattopadhyay pUC1.OM3 + co:Copeland pUC1.OH3 + Mucenski + co:NG Copeland p58.2-1 Morishita Perkins clone 21.1 Bartholomew Evi-1 genomic Mucenski kCB1 through kCB5 Bartholomew ;~2B6 through ZCB15 Bartholomew pUCO.5RP Mueenski pUC1.0HP Mucenski + co:N Copeland [R] pJG19 A] pers + Sweetaer Fabpi e D N A co:JI Gordon cosbF1, pbFAlu co:D Birnbaum [H] pHFL1-7 Abraham + co:J Abraham [R] pyfibl Crabtree + co:GR Crabtree Fire-3 genomic clones co:Gisselbrecht 206-PP20 + co:S Gisselbrecht kl.2,kCBI,kCB1DI,~.1.2A Bartholomew 1.7kb probe + Bartholomew ;~::B16 through ~ B 4 0 Bartholomew pMHFA1 Yachou kI9 + O'Neill k115,XI16,kI20,kI7 O'Neill ~.I35,kI23, genomic clone O'Neill [H] pGC1 Ginns + co:EJ Ginns Gba clone (micresat) + co:JA Todd rnag-1 e D N A co:DM Paulneck Glut-2 e D N A Asano Glut-2 PCR (fr Glut-2 eDNA) + co:A Schultz Glut-2 eDNA-2 Suzue MM614 Graves Taylor pH3.2-614 T ayl or Hurt H2a-614 Hurt Hurt

Referee e

Biochem Genet 1989; 27:17 Genomios 1990; 6:692 Mol Cell Biol 1989; 9:2567 Arteriosclerosis & Thrombosis 1992 (in press) Arteriosclerosis & Thrombosis 1992 (in press) BBRC 1990, 170:1074 J Neumad 1Res1988; 20:497 ref:Gisaelbrocht, Blood 1989; 73:1742 PNAS 1987; 84:1157 Nucl Acid Ros 1987; 15:2389 ref:Baurnbach, J Virol 1988; 62:3151 J Viro11988; 62:3151 J Virol 1988; 62:3151 Oncogene Rea 1988; 2:149 PNAS 1988; 85:6706 Science 1985; 230:291 Science 1987; 235:1504 Nature 1990;, 345:442 Nature 1990, 345:442 Genomics 1992; 12:106 Nucl Acid Ros 1990; 18:4891 Nucl Acid ires 1990; 18:4891 Genomice 1991; 10:375 Genomice 1991; 10:375 ref:Welsh, Nucl Acid Rce 1991; 19:5275 Science 1983; 221:236 Science 1983; 221:236 refiKent, PNAS 1987; 84:5369 PNAS 1985; 82:469 ref:Moseley, Genomios 1989; 5:899 PNAS 1980; 77:5774 PNAS 1980; 77:5579 Genoraios 1989; 5:221 PNAS 1980; 77:5774 ref: Mucenski, Mol Cell Biol 1988; 8:301 Oncogene Res 1988; 2:219 ref:Moseley, Genomios 1989; 5:899 Cell 1988; 54:831 Development 1991; 111:479 Mol Cell Biol 1991; 11:1820 Mol Cell Biol 1988; 8:301 Mol Cell Biol 1991; 11:1820 Mol Cell Biol 1991; 11:1820 Mol Cell Biol 1988; 8:301 Mol Cell Biol 1988; 8:301 reflSola, J Viral 1988; 62:3973 PNAS 1984; 81:313 J Biol Chem 1987; 262:16060 ref:Green, DNA Cell Biol 1992; 11:31 ref:Mattei, Mammal Genome 1992; 2:135 EMBO J 1986; 5:2523 tel:Cox, Genomice 1991; 10:375 J Biol Chem 1981; 256:9718 rof:Cox, Genomice 1991; 10:375 ref: Bordereaux, J Virol 1987; 61:4043 rofiSola, J Virol 1988; 62:3973 Oncogene 1989; 4:529 Oncogene 1989; 4:529 Mol Cell Biol 1991; 11:1820 Genomic8 1991; 9:204 PNAS 1989; 86:5049 PNAS 1989; 86-~5049 PNAS 1989; 56:5049 PNAS 1985; 82:7101 ref:Moseley, Genomios 1989; 5:899 ref:Hearne, M a m m Genome 1991; 1:273 refiJ Immunol 1991; 147:4384 Nucl Acid Res 1989; 17:6386 ref:Hogan, Development 1991; 113:363 Nucl Acid Res 1989; 17:10099 J Mol Biol 1985; 183:179 J Mol Evol 1986; 23:242 J Me1Evol 1986; 23:242

Me1 Cell Bioi 1991; 11:2929 Nucl Acid Res 1989; 17:8876 Mol Cell Biol 1991; 11:2929 Continued on next page

J.T. Eppig: Clones and Probes

325

Table 3. Continued. Cbr Syml:da

3 3

3

3 3

3 3

3

3

3 3 3 3 3 3 3 3 3 3 3

3

Hsp86-ps2 I1-2

~

Name

heat shock protein, 86kDa, pseudogene 2 interleukin-2

~

clones 1, 2, 3,4 MMT-1, MT-20 MT-28, MT-18 p407 pcD-IL-2 II-2 probe pMIL2-20, pMIL2-21, pMIL2-45, pMIL2-58, pMIL2-14 MIL-2G70

RFLVc C~tactd

Moore Yokota Yokota Firestein co:DNAX Research co:IG Young Kashima Kas hi ma Kashima Fuse co:Taniguchi ML2-9.1, ~.IL2-2.1, Novak ML2-11.1, kIL2-7.1, Novak ~.L2-8.1, KL2-10.1 Novak cloned II-2 mlcrosat + co:T Novak MMIL01 (microsat) + co:JA Todd MMIL2A3 (microsat) + co:JA Todd cloned I1-2 microsat + co:JA Todd I1-7 interleukin-7 IIr7 cDNA Namen co:S Gillis + co:RG Goodwin Let'-1 lymphoid enhancer-binding factor-1 LEF1 cDNA Milatovich Ly-37 lymphocyte antigen-37 [=human CD2] kXB2, [H]Tll2 cDNA Clayton MT11.4 Sewell + Moseley + co:WA Sewell T l l cDNA + Clayton kYH2, ~.YI-I16, kY8B Diamond pMCD2-2, pMCD2-3, Yagita pMCD2-5, pMCD2-6, Yagita pMCD2-7 Yagita [R] pRCD2-6 Williams " co:AF Williams Ly-38 lymphocyte antigen-38 [=human CD1] [H]CD1A, [HJCD1B + co:A Aruffo, B Seed [HJCD1D co:S Balk cloned Ly-38 microsat + co:dATodd "Mns-3" minor satellite Chr 3 (centromeric) pMR150 Voliva co:VM Chapman co:ND Hastie Mov-lO Moloney leukemia virus-lO p10-2 + Munke pMov- 10 Harbers probe BK co:R Jaenisch pl0a, pl0b, Mov-10 genomic co:Harbers Mpmv-9 modified polytropic murine leukemia virus-9 JS-4 + Frankel JS-4 + Frankel JH + co:W Frankel Mpmv-10 modified polytropic murine leukemia virus-10 JS-4 Frankel JS-4 + Frankel Mpmv-20 modified polytropic murine leukemia virus-20 JS-4 + Frankel JS-4 + Frankel "Ms2-3-12-Pl" minieatellite 2-3-12-P1 (human D1S57) pYNZ2 + Julier '~Ms6-1-2-P2" minisatellite 6-1-2-P2 (human D14S1) pAW101 + Juliet "Ms6-2-1-PI" minisatellite 6-2-1-P1 (human D14S1) pAW101 + Julier 'WIs6-2-7-PI" minisatellite 6-2-7-P1 (human D14S1) pAW101 + Julier '2VIs6-2-6-P2" minisatellito 6-2-6-P2 (human D14S1) pAW101 + Julier qVls6-3-7-P2" minisatellite 6-3-7-P2 (human D14S1) pAW101 + Julier '~Isll-2-1-P2" minisatellite 11-2-1-P2 (human D17S24) pRMU3 + Julier '~Msll-3-3-PI" minisatellite 11-3-3-P1 (human D17S24) pRMU3 + Juliet Ngfb nerve growth factor ~ pmngf6 Scott + Mucenski + O'Neill + co:GI Bell cDNA-A,cDNA-B, Selby cDNA-C,cDNA-D Selby Ngib genomic, pH2, pH3 Selby mGK-22 Evans Drinkwater MMNGFBA (microsat) + co:JA Todd (micmsat) + co:JA Todd Nras neuroblastoma ras oncogene ~.3.2N-rasT Guerrero Guerrero [HI p6A1 co:M Wigler 95a-4, 92b-4, 15a-2-4, 17b-4 Ryan N8.5, N2.7, N3.8 Ryan pNP-5, pNP-1 co:M Wigler Nras cDNA, T probe Chang Nras genomic Chang

F,~erencee

J Biol Chem 1989; 264.'5343 PNAS 1985; 82:68 PNAS 1985; 82:68 Anal Biochem 1987; 167:381 ref:Webb 1990; Cytogenet Cell Genet 54:164 refiWebb 1990; Cytogenet Cell Genet 54:164 Nature 1985; 313:402 Nature 1985; 313:402 Nature 1985; 313:402 Nucl Acid Res 1984; 12:9323 ref:D'Etmtachio, J Immunol 1988; 141:3067 Nucl Acid ICes 1990; 18:4523 Nucl Acid Res 1990; 18:4523 Nucl Acid Res 1990; 18:4523 ref:Hearne, Mamm Genome 1991; 1:273 ref:Hearne, Mamm Genome 1991; 1:273 ref:Hearne, Mamm Genome 1991; 1:273 ref:Hearne, Mamm Oenome 1991; 1:273 Nature 1988; 333:571 refiWilson, J Exp Med 1990; 171:1301 ref:Siracusa, Genomics 1991; 10:313 Genomics 1991; 11:1040 E u r J Immunol 1987; 17:1367 E u r J Immunol 1987; 17:1015 Genomics 1989; 5:899 ref:Kingsmore, Genomics 1990; 7:75 J Immunol 1988; 140:3617 PNAS 1988; 85:1615 J Immunol 1988; 140:1321 J Immunol 1988; 140:1321 J Immunol 1988; 140:1321 J Exp Med 1987; 165:368 ref:Yagita, J Immunol 1988; 140:1321 ref:Moseley, Immunogenetics 1989; 30:378 ref:Moseley, Immunogenetics 1989; 30:378 ref:Hearne, Mamm Genome 1991; 1:273 Nucl Acid Res 1983; 11:8847 ref:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1983; 11:6965 Cytogenet Cell Genet 1986; 43:140 Nucl Acid Res 1982; 10:2521 ref:Jahner, Molec Cell Biol 1985; 5:2212 ref:Mooslehner, J Virol 1990; 64:3056 Genetics 1990; 124:221 Mamm Genome 1992; 2:110 ref:Gerstein, Cell 1990; 63:537 Genetics 1990; 124:221 Maram Genome 1992; 2:110 Genetics 1990; 124:221 Mamm Genome 1992; 2:110 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 Nature 1983; 302:538 Mol Cell Biol 1988; 8:301 PNAS 1989; 86:5049 ref:Kingsmore, Genomics 1990; 7:75 Mol Cell Biol 1987; 7:3057 Mol Cell Biol 1987; 7:3057 Mol Cell Biol 1987; 7:3057 J Biol Chem 1987; 262:8027 Biochemistry 1987; 26:6750 refiHearne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 Science 1984; 225:1041 PNAS 1985; 82:7810 ref:Guerrero, PNAS 1985; 82:7810 Nucl Acid Res 1984; 12:6063 Nucl Acid Res 1984; 12:6063 ref:Ryan, Nucl Acid Res 1984; 12:6063 Oncogene Res 1987; 1:129 Oneogene Res 1987; 1:129 Continued on next page

J.T. Eppig: Clones and Probes

326 Table 3. Continued. Or Syn~a

3

Ode-rs3

~Name

ornithine decarboxylase related seq-3

3 3 3

op Otf3-rs3 Otf3-rs4

(mutation at Csfm; see Csfm) Otf-3 related sequence-3 Otf-3 related sequence-4

3 3

Oua-1 Pgk-lps3

(see Atplal) pho6phoglycerate kinase-1 pseudogene 3

3

Pray-26

3 3 3 3

Pmv-28 Pmv-38 Pmv-39 Rnulb-1

Rnulb-3 Tpi-2 Tshb

3

Xmmv-22

3 4

Xmmv-65 Akp-2

4 4

Apnh b

4

Calb

4

Ck-1

4 4 4 4 4 4 4 4

Cycb Cyp4a "D4H30" "D4H33" "D4Haml" "D4McCI" "D4McC2" D4Nds3

4

D4Rpl

Probeb

RFLW C a n ~ d

pCR6 (pDOC934 derived) +

Rheaume eo:FG Berger

Mel Endocrinol 1989; 3:1243 ref:Siracusa, Genetics 1991; 127:169

5' Otf-3 cDNA 3' Otf-3 cDNA 5' Otf-3 cDNA

+ + +

Siracusa Siraeusa Siracusa

Genomics 1991; 10:313 Genomics 1991; 1 0 : 3 1 3 Genondcs 1991; 10:313

B10 (pMPGK5-b) genomic clone III JS-5 JS-5, MCF100 JS-5 JS-5 JS-5 UIT-13 U1 RNA-specifie probe " pULl, pU1.2, pU1.3 pUlb-453, pUlb-550 pUP453, pUP550 U1 RNA-specific probe

+

Adra Potten polytropie murine leukemia virus-26 + Frankel + Frankel tmlytrepic murine leukemia virus-28 + Frankel polytropic murine leukemia virus-38 + Frankel polytropic routine leukemia virus-39 * Frankel U l b l small nuclear RNA + Blatt Schenborn Lund Marzluff Howard Michael Ulb3 small nuclear RNA Schenborn + Lund triosephosphate isomerase related seq-2 [H] pHTPI-5A Maquat " + co:LE Maquat thyrotropin stimulating hormone ~ subunit pmTSH~3 Chin co:Chin pTSH-~H Gurr + co:IA Kourides + co:IA Kourides TSH~I, TSH[~2, Gordon TSH~3, TSH~4 Gordon k24, k59, X90 Wolf MUSTSHBA2 (micresat) + co:JA Todd xenotropic-MCF leukemia virus-22 pEnv + Blatt Jenkins xenotropic-MCF leukemia virus-65 pXenv + co:MA Martin alkaline phosphatase-2, liver kmpA, kmpB, Terao kmpC, ~.mpD Terao antiperter, Na+fH+ [H] Apnh eDNA Mattei brown (tyrosinase-like) pMT4, pMT5 Shibahara pMT4 + Jackson + co:I Jack~on + eo:S Shibahara clone 5A Jackson ~.1.6-3, ~.1.0-1, ~.1.6-6 Jackson LAMBP4, kAMBP2, kAMBP1, Shibahara kAMBPS, kBMBP9, kBMBP1 Shibahara calbindin-D28K PCD29, PCD2915, Nordquist PCD2915.1 Nordquist pIBI76 Wood Rhoten [R] p28A Lomri + eo:M Thomasset creatine kinase-1 [H] pCPK-B M ari man + co:ECM Mariman cyclin B family pC5237 Paterno cytochrome P450, 4a [R] IVA1 eDNA Kimura DNA segment, Chr 4, H30 eosmid H30 Boyle DNA segment, Chr 4, H33 cosmid H33 Boyle DNA segment, Chr 4, Hambarg-1 p154 Harbers DNA segment, Chr 4, McClelland-1 AP-PCR oligo KA+KB + co:M MeClelland DNA segment, Chr 4, McClelland-2 AP-PCR oligo KA+KB + eo:M McClelland DNA segment, Chr 4, Nuflield Dept Surg-3 M22991 (microsat) + co:JA Todd (microsat) + eo:JA Todd DNA segment, Chr 4, Roswell Park-1 pMK1440, pMKA11 co: Berger + Elliott pMK1440 + co:RW Elliott pODC1440 + eo:F Berger + +

4 4

D4Rp18 D4Smh6b

DNA segment, Chr 4, R~well Park-18 DNA segment, Chr 4, St Mary's H~p-6b

ReCreate e

eo:F Berger co:R Elliott pCR9 Berger t~/IK174 + co:Mann D4Smh6b + Greenfield cloned D4Smh6b microsat + eo'JA Todd

Somatic Cell Mol Genet 1988; 14:69 Gene 1988; 71:461 J Virol 1989; 63:3810 Mamm Genome 1992; 2:110 J Yirol 1989; 6 3 : 3 8 1 0 J Virol 1989; 6 3 : 3 8 1 0 J Viroi 1989; 63:3810 Somatic Cell Mol Genet 1988; 14:133 Nucl Acid Res 1985; 13:6223 Somatic Cell Mol Genet 1988; 14:143 Nucl Acid Res 1983; 11:6255 Nuel Acid Res 1986; 14:9811 Somatic Cell Molec Genet 1986; 12:215 Nuel Acid Res 1985; 13:6223 Somatic Cell Mol Genet 1988; 14:143 J Biol Chem 1985; 260:.3748 ref:Siracusa, Genetics 1991; 127:169 Endocrinul 1985; 116:873 ref:Naylor, Somat Cell Mol Genet 1986; 12:307 PNAS 1983; 80:2122 ref:Moseley, Genomics 1989; 5:899 ref:Kingsmore, Genomics 1990; 7:75 DNA 1988; 7:17 DNA 1988; 7:17 J Biol Chem 1987; 262:16596 ref:Aitman, Mamm Genome 1991; 1:206 Somatic Cell Mol Genet 1988; 14:133 Nature 1981; 293:370 ref:Wejman, J Virol 1984; 50:237 PNAS 1987; 84:7051 PNAS 1987; 84:7051 Cytogenet Call Genet 1989;, 51:1041 Nuel Acid Res 1986; 14:2413 PNAS 1988; 85:4392 ref:Bahary, PNAS 1990; 87:8642 tel:Fletcher, Genonfics 1991; 9:647 PNAS 1988; 85:4392 Nucl Acid Res 1991; 19:3799 J Biol Chem 1991; 66:15895 J Biel Chem 1991; 66:15895 J Neurceci 1988; 8:4780 J Neurosci 1988; 8:4780 DNA 1988; 7:585 Anat Rec 1990; 227:145 Gene 1989; 80:87 ref:Fletcher, Genomics 1991; 9:647 Genomics 1987; 1:126 ref:Cho, Mamm Genome 1991; 1:30 Gene 1991; 108:315 DNA 1989; 8:517 Genomics 1992; 12:106 Genomics 1992; 12:106 Cytogenet Cell Genet 1990;, 53:129 ref:Welsh, Nucl Acid Res 1991; 19:5275 ref:Welsh, Nucl Acid Rcs 1991; 19:5275 ref:Hearne, Mamm Genome 1991; 1:273 refiMontagutelli, Mamm Genomc 1991; 1:255 J Biel Chem 1984; 259:7941 Mouse News Letter 1981; 64:87 ref:Meistrich, J Hered 1992; 83:56 ref:Huppi,Curr Topics Microbiol Immununol 1988;137:276 ref:Fletcher, Genomic~ 1991; 9:647 ref:Bahary, PNAS 1990; 87:8642 J Biel Chem 1984; 259:7941 Genetics 1986; 114:993 Mouse Genome 1992; 90:94 ref:He~rne, Mamm Genome 1991; 1:273 Continued on next page

327

J.T. Eppig: Clones and Probes Table 3. Continued, Chr S y m ~ a

4

Dsi-1

4

Eno-1

4 4 4

Fabph4 Fabph-4 Fgr

4

Ggtb

4

Glut-1

4

Gnb- 1

4

Hck-2

4

Hck-3

4 4 4

Hrs - 1 Hrs-2 Ifa

L(mas Name

David Steffen integration-1

Probe b

RFLVc Contactd

[R] dsi-HK, dsi-SR [R] pDSI-I-I.1 pBEal, pBE(x2, pBEa3, pBEa4, pBEaS, pBEa6, pBEa7, pBEa8 Eno-1 cDNA 295bp Eno-1 cDNA Sub-S1 pAint [R] H-FABP cDNA [R] H-FABP cDNA [HI c-src-2

Vijaya co:D Steffen Lazar enolase-1 (a, non-neuron) Lazar Lazar Kaghad Barbieri co:AB Pardee + eo:M Lazar fatty acid binding protein, heart-1 Heuckeroth fatty acid binding protein, heart-4 Heuckeroth Gardner-Rasheed feline sarcoma viral co:JM Bishop + co:JM Bishop (Fgr) oncogene homolog mcfgr53 Yi 11FGR King [V] pv-fgr- 1 Tronick glycoprotein 4-~-galactosyltrans feras e MGT-1, MGT-2 Shaper MGT-P1 through-P7 Shaper MGT-1, MGT-2, MGT-4 Shaper MGT-2 probe + Shaper GTcDNA- 1 Lopez GalTase clone Lopez ~1215,~1220,~1216,r Hollis [B] clone 7a Shaper + co:N Shaper [13] el.7A Shaper pCDM7-aGT Larsen glucose transporter protein-l, erythrocyte [R] prGT4-12 Birnbaum + co:M Birnbaum + co:M Birnbaum Glut-1 PCR (from prGT4-12) + co:A Schultz guanine nucleotide binding protein-J31 [B] ~,TB112 Sugimoto + co:M Simon (CIT) hemopeietic cell kinase-2 [HI pHK24 Ziegler + co:Perlmutter [H] pHK24 Ziegler hemopoietic cell kinase-3 + co:Perlmutter mouse minor satellite DNA-1 1.9kb HRS-1 cosmid Brocolli mouse minor satellite DNA-2 2.kb HRS-2 cosmid Brocolli interferon a gene family (leukocyte) pBD2 Daugherty Cahilly ZMIF-2, ~MIF-3, KelIey kMIF-4, ~.MIF-5, Kelley kMIF-6, ~.MIF-8 Kelley INFa + ce:Pitha-Rowe [R] pPC1 Dijkema interferon a (a2, a6) phage 19 Zwarthoff interferon a (al, a4, 3' portion aS) kMIF-1, ~.MIF-9 Kelley interferon ct (al, a4, 3' portion a5) phage 10 Zwarthoff interferon a (al) probe 10EF Zwarthoff pGS1, pGS3 Shaw interferon a (al + flank) pKK16 Kelley interferon a (a2) pMuIFN-a 2 (=a2-17) Shaw + co:Shaw Cheng probe 19EE Zwarthoff pSV-IEE-M VanderKorput pMF1204 Kelley + Nadeau + co:P Pitha + Dandoy + Dandoy + co:E DeMaeyer + co:PM Pitha + co:P Piths-Rowe + co:P Piths-Rowe + co:P Pitha-Rowe interferson a (a3) a3-16 Shaw interferon a (a4) gobe 10EC Zwarthoff interferon a (a4 + flank) pKK12 Kelley interferon a (a5 + flank) pKK15 Kelley interferon a (3' portion a5) probe 10EE Zwarthoff interferon a (3' portion aS) pKK8 Kelley interferon a (a6) probe 19EF Zwarthoff interferon a (a6) pSV10EF VanderKorput interferon a (a6) pKK22 Kelley +

Referencee

J Virol 1987; 61:1164 ref:Ceci, Genomics 1989; 5:699 BBRC 1986; 141:271 BBRC 1986; 141:271 BBRC 1986; 141:271 Nucl Acid Re8 1990; 18:3638 Differentiation 1990; 45:179 ref:Nikaido, Exp Cell Res 1991; 192:102 refiFletcher, Genomic8 1991; 9:647 J Biol Chem 1987; 262:9709 J Biol Chem 1987; 262:9709 ref:Parker, Mol Cell Biol 1985; 5:831 ref: Ceci, Genomics 1989; 5:699 Oncogene 1989; 4:1081 Oncogene 1990; 5:337 PNAS 1985; 82:6595 J Biol Chem 1988; 263:10420 J Biol Chem 1988; 263:10420 PNAS 1990; 87:791 Cytogenet Cell Genet 1990; 54:172 BBRC 1988; 156:1223 BBRC 1988; 156:1223 BBRC 1989; 162:1069 Cytogenet Cell Genet 1987; 44:18 ref:Fletcher, Genomicg 1991; 9:647 PNAS 1986; 83:1573 PNAS 1989; 86:8227 PNAS 1986; 83:5784 ref:Fletcher, Genomic~ 1991; 9:647 ref:Bahary, PNAS 1990; 87:8642 ref:Hogan, Development 1991; 113:363 FEBS Lett 1985; 191:235 ref:Danciger, Genomics 1999; 6:428 Mol Cell Biol 1987; 7:2276 ref:Siracusa, Genetic8 1989; 122:669 Mol Cell Biol 1987; 7:2276 ref:Siracusa, Genetics 1989; 122:669 Genomics 1991; 10:68 Genomics 1991; 10:68 J Interfer Re~ 1984; 4:635 J Inferrer Res 1985; 5:391 N u d Acid Res 1985; 13:805 Nucl Acid Res 1985; 13:805 Nucl Acid Res 1985; 13:805 ref:Ceci, Genomics 1989; 5:699 Nacl Acid Res 1984; 12:1227 Nucl Acid Res 1985; 13:791 N u d Acid Res 1985; 13:805 Nucl Acid Res 1985; 13:791 Nucl Acid Res 1985; 13:791 Nucl Acid Res 1983; 11:555 Nucl Acid Res 1985; 13:805 Nucl Acid Res 1983; 11:555 ref:Lovett, EMBO J 1984; 3:1643 Cytogenet Cell Genet 1986; 41:101 Nucl Acid Res 1985; 13:791 J Gen Virol 1985; 66:493 Gene 1983; 26:181 Genetit~ 1986; 104:1239 ref:Huppi,Cur Top Microb Immun 1988;137:276 J Exp Meal 1984; 160:294 J Virol 1985; 56:216 ret~J Heredity 1987; 78:143 ref:Fultz, J Immtmol 1989; 143:3001 ref:Fletcher, Genomics 1991; 9:647 ref:Bahary, PNAS 1990; 87:8642 ref:Gollahon, Immunogenetics 1992; 35:62 Nucl Acid Res 1983; 11:555 Nucl Acid Res 1985; 13:791 Nucl Acid Res 1985; 13:805 Nucl Acid Res 1985; 13:805 Nucl Acid Res 1985; 13:791 Nucl Acid Res 1985; 13.805 Nucl Acid Re8 1985; 13:791 J Gen Viral 1985; 66:493 Nucl Acid Pea 1985; 13:805 Continued on next page

J.T. Eppig: Clones and Probes

328 Table 3.

Continued.

Chr Symbola

4

4

Ira

Hb

~

Name

interferon interferon interferon interferon

Probeb

a (a6, 5' portion aS) a (ai9-coding) a (al0) ~ (fibroblast)

RFLVc Coatac~

kMIF-7 MuIFN-a9I MuIFN-al0 pM~3, pM~l pMI~,3

+

+

"

+ +

4

Jun

J u n oncogene (avian sarcoma virus 17 homolog)

4

Lck

lymphocyte protein tyrosine kinase

pMIF20/ll Ifb genomic [HI J u n genomic [H] pjun4.gE [H]EMJ-2(fr genomic) + + AHll9 AHll9, Jun-probe T9, NT18, NT5, NT9 NT18 + + + +

4

Lmyc-1

l u n g carcinoma myc-related oncogene-1

clones 1, 2, 42, 65 clones 41.1, 22.2, 6.1, 13.1 clone 96 Lek-PCR/RT Lmyc-l-genomic-1 pL-myc.2nd.exon pML2.1

+ + +

Lmyc-1 eDNA pRll.1 pLMLI.1 [R] pL25, [R] pL14

4

Lv

5-aminolevulinate dehydratase

4

Lyn

Yamaguchi sarcoma viral (v-mye) oneogene homolog

+

[HI pJB-327 + [R] pL32 [R]ZALAD- 1, [R]%ALAD- 3 JR] pALAD-1 + clone B1 +

4

Mmv-15 "Mns-4"

MCF endogenous virus-15 minor satellite Chr 4 (centromeric)

Mos

Moloney sarcoma oneogene

[H] pLYP10 [I-I] plyp2.2 Lyn eDNA lyn6, lyn11, lyn12, Lyn genomic MCF100 pMR159 5're probe 3're probe pMSH

+

+

+ +

Mpmv-19 Mpmv-36 Ms6-2 Ms6hm

kml, kilT1, pHT10, pHTll, pHT13, pml3 kMsarc, pMS1, %HT1 pMS1, mus, UMS probe Mos genomic p-mos pMe [Mk] 7.-m], [Mk] X-HT1 [-Mk] k-ml MAGP31 modified polytropic murine leukemia virus-19 JS-4 JH modified polytropic routine leukemia virus-36 JS-4 minieatellite 6-2 [H] probes 33.6 minisatellite 6 hypermutable kMm3-1 pMm3-1 [H] probe 33.6 M s 6 h m genomic(B6)

+ + + + + +

Referencee

Kelley eo:DeMaeyer,Seif Trapman co:Y Kawade Nadeau eo:Y Kawade c o : Y Kawade Skup Kuga Haluska Haluska eo:Bas,Vogt co:P Vogt Ryseck Mattei Marth co:Marth

Nucl Acid Res 1985; 13:805 refiSeif, Gene 1986; 43: II 1 J Gen Virol 1988; 69:67 ref:Higashi, J Biol Chem 1983; 258:9522 Genetics 1986; 104:1239 refiDandoy, Genormce 1989; 4:546 refiDandoy, J Virol 1985; 56:216 Nucl Acid Res 1982; 10:3069 Nuel Acid Res 1989; 17:3291 PNAS 1988; 85:2215 PNAS 1988; 85:2215 ref:Ceci, Genomics 1989; 5:699 ref:Bahary, PNAS 1990; 87:8642 Nature 1988; 334:535 Oncogene 1990; 5:151 Cell 1985; 43:393 ref:Huppi,Curr Topics Microbiol I ramunol 1988;137:276 eo:R Perlmutter ref:Ceci, Genomics 1989; 5:699 co:R Perlmutter tel:Fletcher, Genorrdcs 1991; 9:647 co:R Perlmutter ref:Bahary, PNAS 1990; 87:8642 Voronova Nature 1986; 319:682 Garvin Mol Cell Biol 1988; 8:3058 Dymecki Science 1990; 247:332 Mori BBRC 1992; 182:527 Zimmerman Nature 1986; 319:780 Legouy EMBO J 1987; 6:3359 Zimmerman Nature 1986; 319:780 Legouy EMBO J 1987; 6:3359 Campbell Oncogene Res 1989; 4:47 Campbell Oncogene Res 1989; 4:47 co:F Alt ref:Fletcher, Genomies 1991; 9:647 Legouy EMBO J 1987; 6:3359 eo:E Legouy ref:Ingvarsson, Oncogene 1988; 3:679 co:Huppi ref:Ceci, Genomics 1989; 5:699 Ingvarsson Sore Cell Mol Genet 1987; 13:335 Ingvarsson Oncogene 1988; 3:679 eo:JD Minna ref:Dolcetti, Nucl Acid Res 1988; 16:11853 Ingvarsson Somatic Cell Mol Genet 1987; 13:335 Bishop PNAS 1986; 83:5568 Bishop PNAS 1986; 83.-5568 Bishop Nucl Acid Rce 1989; 17:1775 eo:T Bishop ref:Fletcher, Genomics 1991; 9:647 Yamanashi Mol Cell Biol 1987; 7:237 ce:T Yamamoto ref:Ceci, Genomics 1989; 5:699 co:Cooke,Perlmutter ref:Yi, Oncogene 1989; 4:1081 Stanley Mol Cell Biol 1991; 11:3399 Stanley Mol Cell Biol 1991; 11:3399 Frankel M a m m Genome 1992; 2:110 Voliva Nucl Acid Res 1983; 11:8847 co:VM C h a p m a n ref:Broccoli, Cytogenet Cell Genet 1990; 54: co:ND Hastie ref:Pietras, Nucl Acid Res 1983; 11:6965 Canaani PNAS 1983; 80:7118 Canaani PNAS 1983; 80:7118 Propst Genomics 1989; 5:118 Eicher Genetics 1990; 125:431 Blair PNAS 1980; 77:3504 Blair PNAS 1980; 77:3504 Osakarsson Science 1980; 207:1222 Wood PNAS 1984; 81:7817 co:SJ O'Brien ref:Threadgill, Genomics 1988; 3:82 Wood J Virol 1983; 46:726 co:G VandeWoude ref:Ceci, Genomics 1989; 5:699 Vande Woude Cold Spring Harbor Sympos 1979; 44:735 eo:G Vande Woude ref:Dandoy, Genomics 1989; 4:546 Cooper Biochemistry 1987; 26:5244 Frankel Genetics 1990; 124:221 co:W Frankel ref:Gerstein, Cell 1990; 63:537 Frankel M a m m Genome 1992; 2:110 Jeffreys Nucl Acid Res 1987; 15:2823 Kelly Genomics 1989; 5:844 Kelly Genomics 1989; 5:844 Jeffreys Nucl Acid Res 1987; 15:2823 Kelly Proc RoyS Lond B 1991; 245:235 C o n t i n u e d on next [

329

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Symbola

~

Name

minisatellite 15-1

Probeb

4

Ms15-1

4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4

"Msl-2-11-P2" minisatellite 1-2-11-P2 (Drosophila Per) pSP.2.5.EI 'WIs1-3-9-P2" minisatellite 1-3-9-P2 (Drosophila Per) pSP.2.5.EI "Ms2-3-10-P2" minisatellite 2-3-10-P2 (human DIS57) pYNZ2 '2Vls2-2-9-P2" minisatellite 2-2-9-P2 (human DIS57) pYNZ2 "Ms2-3-19-P2" rninisatellite 2-3-19-P2 (human DIS57) pYNZ2 '2VIs3-2-13-P2" minisatellite 3-2-13-P2 (human D3S45) pEFD134.7 'WIs3-3-11-P2" minisatellite 3-3-11-P2 (human D3S45) pEFD134.7 'WIs4-3-5-P1" minisatellite 4-3-5-P1 (human D2S44) pYNH24 'WIs5-2-12-P2" minisatellite 5-2-12-P2 pEWRB2.3 'WIs5-3-1-P2" minisatellite 5-3-1-P2 pEWRB2.3 '~Ms5-3-2-P1" minisatellite 5-3-2-P1 pEWRB2.3 'WIs6-3-1-P2" minisatellite 6-3-1-P2 (human D14S1) pAW101 'WIs8-3-12-Pl" minisatellite 8-3-12-P1 (human INS) pINS310 '2Vls9-2-5-P2" minisatellite 9-2-5-P2 (human D17S28) pYNH37.3 '2Vls9-2-7-P2" minisatellite 9-2-7-P2 (human D17S28) pYNH37.3 "Msg-3-3-P1" minisatellite 9-3-3-P1 (human D17S28) pYNH37.3 'WIs9-3-9-Pl" minisatellite 9-3-9-P1 (human D17S28) pYNH37.3 'WIsg-3-10-P2" minisatellite 9-3-10-P2 (human D17S28) pYNH37.3 '~Ms9-3-6-Pl" minisatellite 9-3-6-P1 (human D17S28) pYNH37.3 "Msl0-3-3-PI" minisatellite 10-3-3-P1 (human D17S5) pYNZ22 "Ms10-3-1-P2" minisatellite 10-3-1-P2 (human D17S5) pYNZ22 Mtv-13 mammary tumor virus locus-13 MMTV LTR probe

4

Mtv-13

mammary tumor virus locus-13

4

Mtv-14

mammary tumor virus loct~s-14

4

Mtv-17

mammary tumor virus loctts-17

4

Mup-I

major urinary protein-1

RFLVc C~tac~ t

[H] probes 33.15 P~.Mm3(2) + + + + + + + + + + + + + + + + + + + + + + + + MMTV eDNA or DNA + MMTVS-21,MMTV8-29 + + pMMTV + + pTZ18R-ORF + MMTV5', MMTV3' + IV] MMTV probe + MMTV eDNA or DNA MMTV8-29 + MMTV LTR probe + Mtvl7-3'C, Mtvl7-5'C + Mtvl7-3', Mtv17 -5' MMTV LTR probe + MTV env probe + MMTV eDNA + MTV -LTR + E-P MTV-GRA0 + ev-8, pvc-28 + MMTV eDNA or DNA MMTV8-21,MMTV8-29 + p19 LVA132, LVA318, LVA325, LVA323, LVA324 LVA22 7, LVA325L BS105, BS220, BS201, BS209, BS225, BS222, BS224 BL-14, BS-3, BS-4

Mup, group 1

BL-6, pBS4-4, pBS6-1 MMMUPBS6 (microsat) + (miemsat) + p1057 + +

pCq9 + + +

Mup, group 1 pseudogenel Mup, group la

MUP8, MUP11 BS107e BS108, BS107A, BS100 BS-6

BS-6, pBS6-2, pBS6-5, pBS6-3, pBS6-1

Jeffreys Jeffreys eo:A Jeffreys Julier Julier Julier Julier Julier Julier Julier Julier Julier Julier Julier Julier co:G Bell Julier Julier Julier Julier Julier Julier Julier Julier co:Callahan(NIH) co:Callahan(NIH) eo:J Ball, J Majors Lee Callahan co:B Callahan co:B Callahan co:JE Majors co:G Peters Traina co:J Ball, J Majors Lee co:Callahan(NIH) Peters Peters co:Callahan(NIH) Koizumi Miehalides Michalides Michalides co:Miehalides co:J Ball, J Majors Lee Krauter Clissold Clissold Clissold Clissold Clissold Clark Clark Bishop Clissold Clissold co.'JA Todd co~A Todd Kuhn Eieher co:Bennett co:W Held Sampsell co:W Held co:W Held eo:W Held Clark Clark Clark Clark Clark Bishop Clissold Clissold

P~e~mx~

Nucl Acid Res 1987; 15:2823 Nucl Acid Res 1987; 15:2823 ref:Bahary, PNAS 1990; 87:8642 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 ref:Danciger, Genomics 1990; 6:428 reiiShaper, Cytogenet Cell Genet 1990; 54:172 ref:MacInnes, Virology 1984; 132:12 J Virol 1990; 64:4558 J Virol 1984; 49:1005 ref:Huppi,Cur Top Micro I n . n u n 1988;137:276 ref:Bahary, PNAS 1990; 87:8642 ref:Pullen, J Exp Med 1992; 175:41 ref:Fairchild, Immunogenetics 1991; 34:227 J Virol 1981; 40:735 ref:MaeInnes, Virology 1984; 132:12 J Virol 1990; 64:4568 refiShaper, Cytogenet Cell Genet 1990; 54:172 J Virol 1986; 59:535 J Virol 1986; 59:535 refiShaper, Cytogenet Cell Genet 1990; 54:172 BBRC 1990; 166:336 Virology 1985; 142:278 Virology 1985; 142:278 Virology 1985; 142:278 ref:Meen, Mamm Genome 1991; 1:217 ref:MaeInnes, Virology 1984; 132:12 J Viro11990; 64:4568 J Cell Biol 1982; 94:414 Gene 1981; 15:225 tel:Clark, Gene 1982; 18:221 Gene 1981; 15:225 refiClark, Gene 1982; 18:221 ref:Clark, Gone 1982; 18:221 EMBO J 1984; 3:2055 EMBO J 1984; 3.2O55 EMBO J 1982; 1:615 ref:Clark, Gene 1982; 18:221 ref:Clark, Gene 1982; 18:221 ref:Hearne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 Nuel Acid Res 1984; 12:6073 Genetics 1990; 125:431 PNAS 1982; 79:1220 ref:Kuhn, Nud Acid IRes 1984; 12:6073 Genetics 1985; 109:549 tel:Duncan, Mol Cell Biol 1988; 8:2705 ref:Huppi,Cur Top Microb Immun 1988;137:276 ref:Ceci, Genomics 1989; 5:699 EMBO J 1985; 4:3167 EMBO J 1984; 3:2055 EMBO J 1984; 3:2055 EMBO J 1985; 4:3159 EMBO J 1984; 3:2055 EMBO J 1982; 1:615 ref:Clark, Gene 1982; 18:221 ref:Clark, Gene 1982; 18:221 Continued on next page

J.T. Eppig: Clones and Probes

330 Table 3. Continued. Chr Symbola

~

4

Mup-1

4

Odc-rs4

4

Orm- 1

4

Orm-2

4

Orm-3

4 4

Pax-7 Pgk-lps4

4

Plc

4 4 4 4

Pmv-19 Pmv-23 Pray-25 Pmv-30

4

Pmv-47

4 4

Pray-51 Pnd

Clark EMBO J 1985; 4:3159 Bishop EMBO J 1982; 1:615 Clissold ref:Clark, Gene 1982; 18:221 Clark FAVIBOJ 1984; 3".2055 Al-Shawi J Mol Evo11989, 29:302 A1-Shawi J Mol Evol 1989, 29:302 Held Mol Cell Biol 1987; 7:3705 Bishop EMBO J 1982; 1:615 Mup, group lb Clissold ref:Clark, Gene 1982; 18:221 Al-Shawi J Mol Evol 1989, 29:302 Held Mol Cell Biol 1987; 7:3705 Shahan Mol Cell Biol 1987; 7:1947 Bishop EMBO J 1982; 1:615 Mup, group ic Clissold tel:Clark, Gene 1982; 18:221 Hastie ref:Held, Mol Cell Biol 1987; 7:3705 Al-Shawi J Mol Evol 1989, 29:302 Held Mol Cell Biol 1987; 7:3705 Shahan Mol Cell Biol 1987; 7:1947 Al-Shawi J Mol Evol 1989; 29:302 Mup, group ld Held Mol Cell Biol 1987; 7:3705 BSI02, BSI09 Clark EMBO J 1984; 3:2055 Mup, portions of group 1 and group 2 BL6-25 Held Mol Cell Biol 1987; 7:3705 Map, group 2 (pseudogene?) Clark EMBO J 1985; 4:3159 pBS2-2, pBS3B-3 Bishop EMBO J 1982; 1:615 Map, group 2a (pseudogene?) BS-2, BL-15 Clissold ref:Clark. Gene 1982; 18:221 BS-2, pBS2-2 Clark EMBO J 1984; 3:2055 BS-2, BS-3, BS-4, BL-15 Clark EMBO J 1985; 4:3159 BS-2, BS-3 BS102-2, BS109-2 Al-Shawi J Mol Evo11989, 29:302 Mup, group 2b (pseudogene?) BL-25, CL2 Al-Shawi J Mol Evol 1989, 29:302 Bishop EMBO J 1982; 1:615 BL-25 Mup, group 3 MUP15 Clark EMBO J 1985; 4:3167 co:Held ref:Kuhn, Nucl Acid Res 1984; 12:6073 p199 Shahan Mol Cell Biol 1987; 7:1938 cLIV4, cLIV7 Ma PhD thesis, Univ Edinburgh, Scotland MUP16 Mup, group 4 Al-Shawi J Mol Evol 1989, 29:302 BL-2, CL-12 BL-2, BL-5 Clissold tel:Clark, Gene 1982; 18:221 cLAC 1 Shahan Mol Cell Biol 1987; 7:1938 ornithine decarboxyla~e related seq-4 pCR6 (pDOC934 derived) Rheaume Mol Endocrinol 1989; 3:1243 + co:FG Berger ref:Siracusa, Genetics 1991; 127:169 orosomucoid- 1 Baumann J Biol Chem 1983; 258:563 [R] p10-14 Mol Gen Genet 1985; 201:505 pI RL- 10 + Baumann Cooper J Biol Chem 1986; 261:1849 pMAGP4 co:J Papaconstantinou ref:Carter, BBA 1991; 1089:197 pT7fr3-19-MAGP4 ref:Hearne, M a m m Genome 1991; h 273 MUSAGP1A (micresat) + co:JA Todd (rrficrosat) + co:JA Todd ref:Montagutelli, M a m m Genome 1991; 1:255 (from BALB/c) pMAG14 + Lee DNA 1989; 8:245 (from B10 x AKR/J) pMAG16 Lee DNA 1989; 8:246 Lee DNA 1989; 8:245 orosomucoid-2 pMAG15 Cooper J Biol Chem 1986; 261:1849 pMAGP2, pMAGP3 Mol C.en Genet 1985; 201:505 pIRL-10 + Baumann co:J Papaconstantinou tel:Carter, BBA 1991; 1089:197 pT7/T3-19-MAGP2 co:J Papaconstantinou tel:Carter. BBA 1991; 1089:197 orosomucoid-3 14-A3, oligo agp3(5) co:J Papaconstantinou ref:Carter, BBA 1991; 1089:197 pT7/T3-19-AGP-A3 co:Deutsch, Plachov ref:Jostes, Mechanisrrm of Develop 1991; 33:27 paired box homeotic gene-7 Pax-7 cDNA Somatic Cell Mol Genet 1988; 14:69 phosphoglycerate kinase-1 pseudogene 4 B15(probe pMPGK5-b) + Adra Gene 1988; 71:461 Potten genomic clones I, II M a m m Genome 1991; 1:270 perlecan (heparan sulfate protoglycan) BPG-7 + Chakravarti J Biol Chem 1991; 266:22939 Clones 16, 54, 72, 12, 2D Noonan J Virol 1989; 63:3810 polytropic murine leukemia virus-19 JS-5 + Frankel J Virol 1989; 63:3810 polytropic murine leukemia virus-23 JS-5 + Frankel J Viro11989; 63:3810 polytropic murine leukemia virus-25 JS-5 + Frankel J Viro11989; 63:3810 polytropic murine leukemia virus-30 JS-5 + Frankel + Frankel M a m m Genome 1992; 2:110 J Viro11989; 63:3810 polytropic murine leukemia virus-47 JS-5 + Frankel + Frankel M a m m Genome 1992; 2:110 M a m m Genome 1992; 2:110 polytrepic murine leukemia virus-51 JS-5 + Frankel ref:Mullins, Hypertension 1987; 9:518 pronatriodilatin pCAR6O + co:P Davis ref:Huppi,Curr Topics Microbiol 4co:Mullins lmmunol 1988;137:276 Science 1984; 226:1206 Pnd genomic Seidman + ref:Ceci, Genomics 1989; 5:699 co:J Mullins [a] pANF-44 PNAS 1984; 81:6325 Zivin Am J Hum Genet 1985; 37:1117 Yang-Feng Nature 1984; 309:722 [R] pGH33 M aki ref:Hearne, Mamrn Genome 1991; 1:273 MMANF (microsat) + co:JA Todd Genomics 1990; 6:540 RNA mitochondrial RNA processing RNAase pSP270 Hsieh

Rmrpr

Name

Map, group la

ptxk~b

RFLVc Contactd

Refe~e~z~

pBS6-2, pBS6-5, pBS6-1-1 BL-7, BS-5 BS-5, pBSS-2 BS-5, BS203 BS109-1 CL1 BIZ-3 BS-1 BS-1, pBS1-A10 CIZ BL6-42 cLIV1 BIll BL-I, pBLI-1 BJ-31 CLS, CL6 BL6-11 cLIV6 CL-11 BI/5-51

C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

331

Table 3. Continued. Chr Symh~a

4

~

Name

Rnu3b-ps3 U3B small nuclear RNA pseudogene 3

Probeb

RFLVc Cmtac~l

pEBu

prob~P, g~be U 4

Rrm2-psl

ribonucleotide roductase M2, pseudo-1

4

Scl Ski "Tag-Rb" Tnfr-1

homolog of h u m a n stem-cell leukemia gene SCL eDNA Sloan-Kettering viral oncogene homolog [H] Ski eDNA SV40 T antigen transgene (retinoblastoma) SP6TagHB tumor necrosis factor receptor-1 mTNT-R1 eDNA TNFR- 1 eDNA thyrotropin stimulating hormone a subunit pTSHa-1, pTSHa-2

4 4 4

Tsha

clone 21 Rrm2 eDNA

mTSHa

Wnt-4 Xmmv-8 Xmmv-23 Xmmv-62 Xmv-8 Xmv-9 Xmv-14 Xmv-44 Xpa Actb

A~

Alb-i

(5' end ofgene + flank) Tsha genomic- 1 (3' end ofgene + flank) Tsha genomic-2 wingless-related MMTV integration site-4 Wnt-4 eDNA Wnt-4 genomic xenotropic-MCF leukemia virus-8 pMo-MCFl-16 + xenotropic-MCF leukemia virus-23 pMo-MCFl-16 + xenotropic-MCF leukemia virus-62 pXenv + xenotrepic murine leukemia virus-8 JS-6cJS-IO + xenotropic murine leukemia virus-9 JS-6flS-10 + xenotropic murine leukemia virus-14 JS-6~]S-10 + xenotrepie murine leukemia virus-44 JS-6flS-10 + xerederma pigmentosum, EMBL3/24B, EMBL3/60A (complementatlon group A) pHC79/443, pHC79/700 pcD2ml3, pcD2m95 actin, cytoplasmic pAL41 +

alpha fetoprotein

s e r u m albumin variant

genomic 5' to A]b-1

]328, l~5'-Gem4 clone B2 JR] pAc18-1, JR] ActI ['R] pAcl8-1 Actb eDNA PCR-Actb LG-80 unnamed unnamed Alp probe MAF1, MAF2 pAFP7B pBR322-AFP1 pHcII440 pMAFP189,pMAFP191 XAFPI4, kAFPI5 kAFPT, ~.AFP8 MMFTPR (microsat) MSA1, MSA3 pMSA433 pMSA433,pMSA962 LVA304 kalb6, kalb5, XAFP15 pmalb2 pAlb576 p1706 pAlbH

+

+

+ + 4-

+ +

+ + +

Alb-LIMd Asl Bmp-3

L1 sequence in intron 12 of Alb-1 arg/nosuceinate lyase bone morphogenetie protein-3

Cncg

+ cyclic nucleotide gated channel, cGMP gated MCC-13 MCC-3, MCC-2, MCC-33, PCR-MCC casein gene family (a,]3,T) pCMTI9, pCM540, pXMI-14 a casein pCMal 1 casein ;~csn35,~.!]scn42,~.~scn43 Csnb eDNA

kalb6 probes Asl5-1 BMP3-315

+ + +

Csn Csna Csnb

~M~13

Mazan Mazan Thelander Thelander Yang-Feng co:L Thelander Begley co:N Nomura co:Gluzman Lewis Goodwin Chin Naylor Schorr-Toshav co:IA Kourides Konrides Gordon Gordon Gavin Gavin co:M Vogt co:M Vogt co:MA Martin Frankel Frankel Frankel Frankel Tanaka Tanaka Tanaka co:Minty Alonso Elder Almendral Nudel Czosnek Tokunaga Tel ford co:AB Pardee Gorin Law co:S Tilghman eo:Sonner eo:S Tilghman co:S Tilghman co:Tilghman co:Tilghman Sala-Trepat Ingram Ingram co:JA Todd eo:Bonner Bellis Sala-Trepat Clissold Ingram co:Tilghman co:JM Taylor co:Hastie,Barth co:Tilghman co:Tilghman Hill co:Tilghman Todd Wozney co:Wozney co:W Baehr co:W Baehr co:W Baehr Gupta Gupta Gupta Yoshimura Yoshimura Gupta

Referencee

E u r J Biochem 1989; 181:599 Cytogenet Cell Genet 1991; 56:18 Mol Cell Biol 1986; 6:3433 Mol Cell Biol 1986; 6:3433 Genomics 1987; 1:77 ref:Ceci, Genomics 1989; 5:699 PNAS 1991; 88:869 ref:Goodwin, Mol Cell Biol 1991; 11:3020 ref:Windle, Nature 1990; 343:665 PNAS 1991; 88:2830 Mol Cell Biol 1991; 11:3020 PNAS 1981; 78:5329 Somatic Cell C~net 1983; 9:757 Endocrinology 1983; 112:1434 ref:Ceci, Genomics 1989; 5:699 PNAS 1984; 81:517 DNA 1988; 7:679 DNA 1988; 7:679 Genes & Development 1990; 4:2319 Genes & Development 1990; .4:2319 ref:Blatt, PNAS 1983; 80:6298 ref:Blatt, PNAS 1983; 80:6298 ref:Wejman, J Virol 1984; 50:237 J Virol 1989; 63:1763 J Virel 1989; 63:1763 J Virol 1989; 63:1763 J Virol 1989; 63:1763 PNAS 1989; 86:5512 PNAS 1989; 86:5512 Nature 1990; 346:73 J Mol Biol 1983; 167:77 J Mol Evol 1986; 23:11 Mol Cell Biol 1988; 8:480 Mol Cell Biol 1988; 8:2140 PNAS 1982; 79:2763 EMBOJ 1982; I:1299 Nuel Acid Res 1986; 14:2829 Mol Repred Devel 1990:27:81 ref:Nikaido, Exp Cell Res 1991; 192:102 FNAS 1980; 77:1351 Gene 1980; 10:53 ref.'Smith, PNAS 1991; 88:4811 ref:Cooper, Nucl Acid Res 1984; 12:6575 ref:Campbell, Oncogene Res 1989; 4:47 ref:Danciger, Genomics 1990; 6:428 refiBelayew, Mol Cell Biol 1982; 2:1427 ref:Birkenmeier, J Clin Invest 1989; 83:1258 PNAS 1985; 82:2442 PNAS 1981; 78:4694 PNAS 1981; 78:4694 ref:Aitman, M a m m Genome 1991; 1:206 refiCooper, Nucl Acid Res 1984; 12:6575 Mol Biol Evol 1987; 4:351 PNAS 1985; 82:2442 Gene 1981; 15:225 PNAS 1981; 78:4694 ref:Gupta, J Cell Biol 1982; 93:199 tel:Morrow, PNAS 1981; 78:4718 ref:Baumann, J Biol Chem 1983; 258:563 ref:Mock, J Immunol 1989; 142:1372 ref:Dickinson, Genomics 1990; 6:505 Genes & Dev 1989; 3:26 refzBoccaccio, Gene 1990; 88:181 Genomics 1989; 4:53 Science 1988; 242:1528 ref:Dickinson, Genomics 1990; 6:505 ref:Pittler, J Biol Chem 1992; 267:6257 ref:Pittler, J Biol Chem 1992; 267:6257 ref:Pittler, J Biol Chem 1992; 267:6257 J Cell Biol 1982; 93:199 J Cell Biol 1982; 93:199 J Cell Biol 1982; 93:199 C-ene 1989; 78:267 Nucl Acid Res 1986; 14:8224 J Cell Biol 1982; 93:199 C o n t i n u e d on next p a g e

332 Table 3.

J.T. Eppig: Clones and Probes Continued.

Chr Symbola

Locus Name

Probeb

5

Csnb

5 5

Cv-1 Cyp3

(withdrawn, = Emv-1) cytochrome P-450, 3, steroidinducible

5

D4S43h

D N A segment, Chr 5, human D4S43

5 5 5 5

D4S62h IMS76h D4Sa0h "DSGotl"

5 5 5 5 5 5

"D5H6" "DSH13" "DSH17" D5Lehl D5Mit25 D5Pasl

D N A segment, Chr 5, human D4S62 D N A segment, Chr 5, human D4S76 D N A segment, Chr 5, human D4S80 D N A segment, Chr 5, Gothenburg Univ-1 (class 5 gene) D N A segment, Chr 5, H6 cosmid H6 D N A segment, Chr 5, H13 cesmid H13 D N A segment, Chr 5, H17 cesmid H17 D N A segment, Chr 5, Lehrach-1 B2 SINE (GACA) 3 (see D5Sc25) DNA segment, Chr 5, Pasteur Instituto-1 probe AP

5 5 5

D5Sc25 Dao-1 Emv-1

DNA segment, Chr 5, S Cheng-25 D-amino acid oxidase endogenous ecotropic MuLV-1

casein

RFLVr C a a ~ "d

pA200 Csnb genomic

co:Henninghausen Goodman

[R] pP-450PCN-10

Hardwick + Simmons + Cheng + co:Cheng, Gusella + Cheng + Cheng + Cheng co:A VanderBliek

[H] HB1.4 [H]C9AHB1.4 [H] p8 [H] 8MD4 [H] B5E [CH]cp30

+ + + +

pMDA015 U 3 L T R -MuLV pBW50 + +

Emv-24

endogenous eeotropic MuLV-24

En-2

engrailed-2

Epo

erythropoietin

Eta Fgf-5

(rearranged) early T lymphocyte activation fibroblast growth factor-5

Flk-1 ~t-3

fetal liver kinase-1 FMS-like tyrosine kinase-3

Fsp Gc Gig

fibroblast secretory protein (Pdgf, bombesin stimulated) group-specific component Gus intermingled gene

Gnb-2

guanine nucleotide binding protein-~2

Gsh - I Gsh-2 Gsh-3 Gus

genomic screened homeo box-1 genomic screened homeo box-2 genomic screened homeo box-3 ~-glucoronidase

Gus-s

~-glucoronidase-structural

pEoa " pEco pEc-B4 pEco, pEc-B4 mp2 " "

+ + + + + +

En-2c, kEn-2.1, ken-2.2 pk8, pXSSR, tAAL7 clonel2.a Epo genornic + kMGla Epo probe + clone 18.c poD-Eta-1 + Fgf-5 genomic pmFGF-5 Flk-1 probe, Flk-1 eDNA + pFT5 MP14, MP37, MP58, FT5 USX probe N51 2B, 33Z, 9X PPv318, pBSGUS-1 Gua-s genomic [B] ~.TB112 clone 23h clone 9t done 15h pGUS2 ccsB1 [HI pHGUS MUSGUSB (microsat) pGA-1, pGA-6 pGA-2, pGA-3, pGA-5 pGA-1 pGA-1 Guam genomic PPv318, pBSGUS-1 pGUS-I

+ + + +

+ + + +

+ + "

+

+ +

Boyle Boyle Boyle Cox

l~fc~ncee

ref:Schoenenberger, EMBO J 1988; 7:169 Mol Endocrinol 1990; 4:1661 J Biol Chore 1983; 258:10182 J Biol Chem 1985; 260:515 Genomica ].989; 4:419 ref:Hill, Genes & Dev 1989; 3:26 Genomics 1989; 4:419 Genomics 1989; 4:419 Genomics 1989; 4:419 ref:Stahl, Mol Cell Biol 1992; 12:1179 Genomics 1992; Genomics 1992; Genomies 1992; Genomics 1991;

12:106 12:106 12:106 10:375

Lacombe Bach Cheng Tada Khan Chattopadhyay Cheng Eicher Chattopadhyay co:NG Copeland Chattopadhyay Chan Taylor Joyner co:A Joyner co:A Joyner co:A Joyner Joyner Davidson McDonald McDonald Lacombe Shoemaker co:E Goldwasser McDonald Patarca Haub co:M Goldfarb co:Lemischka co:D Birnbaum co:D Birnbaum co:D Birnbaum Ryseck

Blood 1988; 72:1440 Genomics 1990; 8:155 Genomics 1989; 4:419 Gone 1990; 90:293 Nucl Acid Res 1987; 15:7640 PNAS 1980; 77:5774 Genomics 1989; 4:419 Genetics 1990; 125:431 PNAS 1980;77:5774 ref:Jenkina, Cell 1985; 43:811 PNAS 1980;77:5774 PNAS 1980;77:5579 Genomics1989;5:221 Genes & Dev 1987; 1:29 ref:Mock, J Immunol1989; 142:1372 tel:Hill, Genes & Dev 1989; 3:26 ref:Dernoncourt, Genomics1991; 11:1167 Genes & Dev 1987; 1:29 Development1988; 104:305 Mol Cell Biol 1987; 7:365 Mol Cell Biol 1986; 6:842 Blood 1988; 72:1440 M o l Cell Biol 1986; 6:849 ref:Singh, PNAS 1991; 88:10706 Mol Cell Bid 1987; 7:365 J Exp Meal 1989; 170:145 PNAS 1990; 87:8022 ref:Mattei, Mammal Genome 1992; 2:135 refiMatthews, PNAS 1991; 88:9026 ref:Roanet, Genomics 1991; 9:380 ref:Resnet, Oncogene 1991; 6:1641 ref:Rosnet, Oncogene 1991; 6:1641 Exp Cell Res 1989; 180:266

Yang Wang Wang Sugimoto co:M Simon (CIT) Singh Singh Singh co:Granschow co:Meisler Kyle co:JA Todd Watson Watson co:Watson co:Watson Wang Wang co:Ganschow Hill Either co:Ganschow co:Gansehow co:Gansehow

Genomics 1990; 7:509 J Biol Chem 1988; 263:15841 J Biol Chem 1988; 263:15841 FEBS Lei~ 1985; 191:235 ref:Danciger, GenorrAcs 1990; 6:428 PNAS 1991;88:10706 PNAS 1991;88:10706 PNAS 1991;88:10706 rehBevilacqua, PNAS 1988; 85:831 ref.'Bevilacqua, PNAS 1988; 85:831 PNAS 1990;87:3914 ref'.Hearno, MammGenome 1991; I: 273 Gone 1985;36:15 Gene 1985; 36:15 ref:Danciger, Genomics 1990; 6:428 ref:Meen, M a m m Genome 1991; 1:217 J Biol Chem 1988; 263:15841 J Biol Chem 1988; 263:15841 ref: Palmer, PNAS 1983; 80:7596 Genes & Dev 1989; 3:26 Genetics 1990; 125:431 tel:Mock, J Immunol 1989; 142:1372 ref:Dickiuson, Genomics 1990; 6:505 ref:Birkenmeier, J Clin Invest 1989; 83:1258 C o n t i n u e d on n e x t p a g e

333

J.T. Eppig: Clones and Probes Table 3. Continued, Chr Symbola

Gus-s a

Loc~ Name

~-glucoronidase-structural, a allele

Gus-sb

~-glueoronidase-structural, b allele

5

Hox-7

homeo box cluster 7, rash like

5

Hox-7.1

homeo box 7, msh like, gene 1

5

Igj

5

I1-6

interleukin-6

5

Kit (W)

kit oneogene

immunoglobulin joining gene

W37/W37 mutant Kit

P~

pGUS7, pGUSS, pGUS48 pGUS7, pGUS5 pGUS48, pGUS22 pGUS142, p G U S 1 2 1 GusA21,GusA12,GusA17 XGC-1 kAGus-4 XGB10-1 pGY-1 + pGY-1-ES, pGY-1-B73 + pGY-1-B40, pGY-1-B51 + ),BGas-2, cesBGus- 1 cosl, ces5a, cos6a Hox-7/B12 + MMHOX71 (mierosat) + pMHX2 + rash1 PCR clones pJc3 pJc3, pJc4, pJcS, pJc6, pJcO, pJcl0, l~Iell MJ-cDNA pHP1A4, pHP1B5 pHP1B5 + kIL6-1O, ~.IL6-18, ML6-3, ML6-17 pcD-mlL-6 I1-6 eDNA-l, II-6 eDNA-2, pXM-6, pXM-27 + + rolL-6 mIL-6 eDNA MMIL6A (microsat) + (microsat) + (micmsat) + [V] v-kit (feline) + [V] v-kit, [V] HZ4-FeSv [H] phckit-171 + 5.1 kb Kit eDNA 3.3 kb Kit eDNA 4.3 kb Kit eDNA + pK3A + + Kit eDNA-1 + Kit eDNA-2 + Kit eDNA-3 + Kit eDNA-1 + phekit-171 W37 eDNA W55 eDNA W41 eDNA 1.35, X L1.M1, ML6-10 L1.M2, ~.IL6-10 L1.M3, ~.IL6-3 CI-3-LTR + pBC-KC KC-probe + MCFI00 + pMRI50

5

W55/W55 mutant Kit W41/W41 mutant Kit LIMd LINE element in Alb-1, Alp "L1.MI(II-6)" L1 repeat, I1-6 associated-1 "L1.M2(I]-6)" L1 repeat, I1-6 associated-2 "L1.M3(II-6)" L1 repeat, I1-6 associated-3 Ltrm-3 LTR mink cell focus-forming murine leukemia viral locus-3 Mgsa melanoma growth stimuIatory activity

5 5

Mmv-19 "Mns-5"

MCF endogenous virus-19 minor satellite Chr 5 (centromerie)

5 5

Mor-i Mpmv-7

5 5

Mpmv-13 Mpmv-23

5 5

Ms15-5 Ms15-6

malate dehydrogenase, mitochondrial Cos mmMDH-1 modified pelytropic murine leukemia virus-7 JS-4 JS-4 pMo-MCFl-16 JH modified polytrepic routine leukemia virus-13 JS-4 modified polytropic murine leukemia virus-23 JS-4 pXenv minisatellite 15-5 [H] probes 33.6, 33.15 minisatellite 15-6 [H] probes 33.6, 33.15

5 5 5 5 5

RFLVc C c ~ c t d

+ + + + + + +

Catterall ' Watson Funkenstein Funkenstein Funkenstein Funkenstein co:Paigen Gallagher co:Paigen co:Paigen Moore Moore Gallagher Robert Robert co:JA Todd Hill Holland eo:Koshland Mather Mather Cann VanSnick co:VanSnick Qin Qin Chiu Mock Mock Mock co:BA Mock Grenett Grenett co:JA Todd co:JA Todd eo:JA Todd Chabot Besmer Yarden Hill Besmer Orr-Urtreger eo:VM Chapman Geissler eo:D Housmaa Geissler Geissler Geissler co: P Besmer eo:ATCC Reith Reith Reith Cooper co:T Blankenstein co:T Blankenstein ce:T Blankensteia Rapp Eicher Cochran eo:CD St~les Frankel Voliva eo:VM Chapman co:ND Hastie Takeshima Frankel Frankel co:M Vogt co:W FrankeI Frankel Frankel co:MA Martin Jeffreys Jeffreys

Ref~meee

Biochemistry 1983; 22:6049 Ann NY Acad Sei 1984; 438:101 Mol Cell Biol 1988; 8:1160 Mel Cell Biel 1988; 8:1160 Mol Cell Biol 1988; 8:1160 Mol Cell Biol 1988; 8:1160 ref:Moore, Genemica 1988; 2:25 Genomics 1987; 1:145 ref:Moore, Genomica 1988; 2:25 ref:Moore, Genomica 1988; 2:25 Genomics 1988; 2:25 Genomics 1988; 2:25 Genomics 1987; 1:145 EMBO J 1989; 8:91 EMBO J 1989; 8.<91 ref.'Aitman, Mamm Genome 1991; 1:206 Genes & Dev 1989; 3:26 Gene 1991; 98:253 refiYagi, J Exp Med 1982; 155:647 Cell 1981; 23:369 Cell 1981; 23:369 PNAS 1982; 72:6656 E u r J Irnmunol 1988; 18:193 refiQin, Mol Immunol 1989; 16:1021 Mol Immunol 1989; 16:1021 Mol Immunol 1989; 16:1021 PNAS 1988; 85:7099 J Immunol 1989; 142:1372 J Immtmol 1989; 142:1372 J Immanol 1989; 142:1372 ref:Hill, Genes & Dev 1989; 3:26 Nucl Acid Res 1990; 18:6455 Gene 1991; 101:267 ref:Hesrne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 ref:Aitman, Mamm Genome 1991; 1:206 Nature 1988; 335:88 Nature 1966; [email protected] EMBO J 1987; 3:3341 Genes & Dev 1989; 3:26 EMBOJ 1988; 7:1003 Development 1990; 109:911 ref:Stephenson, PNAS 1991; 88:6 Cell 1988; 55:185 ref:Smith, PNAS 1991; 98:4811 Cell 1988; 55:185 Cell 1988; 55:185 Cell 1988; 55:185 refiKoopman, Nature 1990; 348:450 ref:Hsieh, Cytogenet Cell Genet 1991; 56:160 Genes & Devei 1990; 4:390 Genes & Devel 1990; 4:390 Genes & Devel 1990; 4:390 Nucl Acid Res 1984; 12:6575 ref:Qin, Immunogenetics 1991; 33:260 ref:Qin, Immunogenetics 199]L; 33:260 ref:Qin, Immunogenetics 1991; 33:260 J Virol 1983; 45:740 Genetica 1990; 125:431 Cell 1983; 33:939 ref:Sakaguchi, Genomies 1989; 5:629 Mamm Genome 1992; 2:110 Nucl Acid Res 1983; 11:8847 tel:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1983; 11:6965 JMol Biol 1988; 200:1 Genetic~ 1990; 124:221 Mamm Genome 1992; 2:110 refi Blatt, PNAS 1983; 80:6298 ref:Gerstein, Cell 1990; 63:537 Genetics 1990; 124:221 Genetics 1990; 124:221 ref:Wejman, J Virol 1984; 50:237 Nucl Acid Res 1987; 15:2823 Nucl Acid Res 1987; 15:2823 Continued on next page

334

J.T. Eppig: Clones and Probes

Table 3. Continued. Chr Symkda

5 5 5 5 5 5 5 5 5 5 5 5 5 5 5 5

Locus Name

'WIsl-2-3-PI" minisatellite 1-2-3-P1 (Drosophila Per) 'WIs4-1-3-P2" minisatellite 4-1-3-P2 (human D2S44) '2Vls4-1-7-Pl" minisatellite 4-1-7-P1 (human D2S44) '2Vls4-2-11-P2" minisatellite 4-2-11-P2 (human D2S44) 'WIs4-3-12-P2" minisatellite 4-3-12-P2 (human D2S44) "Ms5-3-3-P2" minisatellite 5-3-3-P2 'WIs6-1-4-Pl" minisatellite 6-1-4-P1 (human D14S1) 'WIs6-1-S-P2" minisatellite 6-1-5-P2 (human D14S1) '2r miniaatellito 6-2-5-P2 (human D14S1) 'WIs6-2-9-PI" minisatellite 6-2-9-P1 (human D14S1) 'WIs6-3-2-Pl" minisatellite 6-3-2-P1 (human D14S1) 'WIsT-3-4-P2" minisatellite 6-3-4-P2 (human D14S1) "Ms7-3-8-Pl" minisatellite 7-3-8-P1 (human RB1) Mtv-32 m a m m a r y tumor virus locus-32 Mtv-41 m a m m a r y tumor virus locus-41 (called Mtv-31 in reference) Nmyc-2 neuroblastoma myc-related oncogene-2

Probeb

RFLVc Contac~

pSP.2.5.EI pYNH24 pYNH24 pYNH24 pYNH24 pEWRB2.3 pAW101 pAW101 pAW101 pAW101 pAW101 pAW101 p68RS2.O MMTVS-21 MMTVS-21

+ + + + + + + + + + + + + + +

pM.2 +

5 5

Pal-1 Pdeb

proviral insertion Pal-1 eGMP-phosphodiesterase, [~ subunit

Pal-1 PCR zr.408 MPB-1, MPB-9, MPB-1C PCR 80/83, 89/91, 82/102 RT-1

5

Pdgfa

platelet-derived growth factor a chain

5

Pdgfra

platelet-derived growth factor receptor a

5

Pgy-1

5

Pgy-2

5

Pgy-3

5

Pmv-5

5

Pmv-ll

5 5 5 5 5 5

Pmv-12 Pmv-40 Pmv-49 Pmv-53 Pol-20 Qdpr rd Rec- 1

P glyeoprotein-1 (multidrug resistance)

+ +

Pdgfra eDNA + 3' Pdgfra eDNA + 5' Pdgfra eDNA Pdgfra probe + [H] 12 PstrRI [HI Pdgfra eDNA1 + [HI Pdgfra probe 1 + kDR11,pcDR1.3,kDR29 probe A1, A2 (from DR11) EDRll pcDR1.4, pcDR1.5 [CH] pDR7.8, pDR1.6 [CH] cp28

Ie7 [CH] pCHP-1 + [CH] Pgy-1 probe + kDRll, kDR29, ;~DR13, Pgy-1 eDNA, peDR1.3 pSPTMol P glycoprotein-2 (multidrug resistance-2) kDR29, ~.DR27 ~J)Rll, ZDR29, kDR13, Pgy-2 eDNA, peDR1.3 probe B (from DR29) pSPTMol [CH]cp28 P glycoprotein-3 (multidrug resistance-3) kDRll, ~.DR29, ~.DR13, Pgy-3 eDNA, pcDR1.3 probe C (from DR13) kDR14, kDR15, pDR16 cosmuDRl5 pGBMo2 [CH]cp28 polytropie murine leukemia virus-5 JS-5 + + polytropic murine leukemia v i r u s - l l JS-5 + + polytropie routine leukemia virtm-12 JS-5 + polytropie murine leukemia vimm-4O JS-5 + polytropic murine leukemia virus-49 JS-5, MCF100 + polytropic murine leukemia virus-53 JS-5 + viral polymerase-20 B65.5PV2 derivative + quininoid dihydropteridine reductase [HI DHPR.9 + [H] DHPR13 + retinal degeneration (see Pdeb) ecotropic MuLV receptor-1 W1, W2, W3 Rec-1 eDNA +

Referencee

Julier Julier Julier Julier Julier Julier Juliet Juliet Julier Julier Juliet Julier co:T Dryja eo:JE Majors co:JE Majors

PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 ref:JulieL PNAS 1990; 87:4585 ref:Siracusa, Genetics 1991; 127:169 ref:Siraeusa, Genetics 1991; 127:169

Zimmerman co:P D'Eustaehio vanLohuizen Bowe~ Danciger Baehr Pittler Tong Yeh Mereola co:VM C h a p m a n co:VM C h a p m a n co:VM C h a p m a n eo:U Drager Hsieh co:AY Sakaguchi co:Lemischka Gros Raymond Gros Gros Gros VanderBliek Jakobsson Martinsson eo:A VanderBliek co:A VanderBliek co:ATCC #39839 co:B Roninson Creep Creep Tetter Gros Creep Creep Raymond Tetter co:A VanderBliek Creop Croop Raymond Devault Ikeguehi Tetter eo:A VanderBliek Frankel Frankel Frankel Frankel Frankel Frankel Frankel Frankel Rossomando Cheng co:W Baehr

Natmce 1986; 311k.780 tel:Campbell, Oncogene Res 1989; 4:47 Cell 1991; 85:737 PNAS 1989; 86.0722 Invest Ophthalmol Vis Sci 1990; 31:1427 FEBS Let~ 1991; 278:107 PNAS 1991; 88:8322 Nature 1987; 328:619 Cell 1991; 64:209 Devel Biol 1990; 138:114 ref:Stephenson, PNAS 1991; 88:6 refiStephenson, PNAS 1991; 88:6 ref:Stephenson, PNAS 1991; 88:6 ref:Singh, PNAS 1991; 88:10706 Cytogenet Cell Genet 1991; 56:160 ref:Smith, PNAS 1991; 88:4811 refiMatthews, PNAS 1991; 88.0026 Nature 1986; 323:728 Mol Cell Biol 1990; 10:1642 Cell 1986; 47:371 Nature 1986; 323:728 PNAS 1986; 83:337 Mol Cell Biel 1986; 6:1671 Anticanc Re~ 1988; 8:307 Cytogenet Cell Genet 1987; 45:99 refiStahl, Mol Cell Biol 1992; 12:1179 refiStahl, MoI Cell Biol 1992; 12:1179 ref:Dernoncourt, Genomics 1991; 11:1167 ref:Singh, PNAS 1991; 88:10706 Mol Cell Biol 1989; 9:1346 Mol Cell Biol 1989; 9:1346 DNA Ceil Biol 1991; 10:433 Mol Cell Biol 1988; 8:2770 Mel Cell Biol 1989; 9:1346 Mol Cell Biol 1989; 9:1346 Mol Cell Biol 1990; 10:1642 DNA Cell Biol 1991; 10:433 ref:Stahl, Mol Cell Biol 1992; 12:1179 Mol Cell Biol 1989; 9:1346 Mel Cell Biol 1989; 9:1346 Mol Cell Biol 1990; 10:1642 Mel Cell Biol 1990; 10:1652 DNA &Cell Biol 1991; 10:639 DNA Cell Biol 1991; 10:433 ref:Stahl, Mol Cell Biol 1992; 12:1179 J Virel 1989; 63:3810 M a m m Genome 1992; 2:110 J Virol 1989; 63:3810 M a m m Genome 1992; 2:110 J Virol 1989; 63:3810 J Virol 1989; 63:3810 Marnm Genome 1992; 2:110 M a m m Genome 1992; 2:110 Immunogenetics 1986; 23:233 Genomics 1989; 4:419 ref:Pittler, J Biel Chem 1992; 267:6257

Albritton Kozak

Cell 1989; 57:659 J Virol 1990; 64:3119 Continued on next page

J.T. Eppig: Clones and Probes

335

Table 3. Continued. Chr Symbda

Lor Name

5

Spp-1

secreted phosphoprotein-1 (includes osteopontin)

5

Sri

sorein

5

Tcf-1

transcription factor-1

5

Udpgt-3

UDP glueuronosyltrans ferase- 3

Probeb

RFLVc Contactd

2ar eDNA OpnI-cDNA MS21, 12G26 ~9590 [CH] pCP7 [CH]cp6 [R] CD26 [R] NcoI-fragment JR] Hnf-1 eDNA (PCR) ~32, k24, k4a k4b JR] pUDPGTr3 JR] pUDPGTr4

+

+

+ + +

pUDPGTm. 1 Xgtl 1UDPGT m_1 5 5 5

W Xmmv-5 Xmv-17

dominant spotting, (see Kit above) (withdrawn, see Mpmv-7) xenotrepic murine leukemia virus-17

5 5 5

Xmv-28 Xmv-34 Xmv-38

xenotrepie murine leukemia virtm-28 xenotrepic murine leukemia virtu-34 xenotropic murine leukemia virus-38

5

Xmv-45

xenotropic murine leukemia virus-45

5

z;-3

JS-6flS-1O JS-6+JS-1O, XENOll2 JS~flS-10 JS-6flS-10 JS-6flS-10

+ + + +

+ +

zona pellucida g]yeopretein-3

JS-6flS-10 JS-6+JS-10, XENO 112 pZP3.1, pZP3.2

+

actin related gene-4

pZP3.2 kZP3G.I,XZP3G.2 Zp-3 genomic MMZP3G (microsat) [C] 13~oo

+

6

Act-4

6

Actg

6

Braf-2

Braf transforming gene-2

GA63 pmGl,pmG2,pmG3, pmG4,pmG5 pmTAc Actg cDNA PCR of 3' Actg eDNA [H] pEX

Cbl-1

Braf related oncogene (B) Casitas B-lineage lymphoma-1

Braf 42mer v-cbl probe 2

+ + +

cytoplasmic actin ~', smooth muscle

+

6

+ + +

6

Clc-1

chloride channel-l, skeletal muscle

6

Cola-2

procollagen type I, a2

cDNA-1, -2, -3, -4 Clc-1 probe pAZl003, pAZ1009

+

pAZlO01 +

;~-colm212, PAZ1002 [H] Hf32

Cpa

carboxypeptidase A

[H] NJ3 3.2 [RJ 11-3

Cpa probe

"D6?" D6Lehl D6Mul D6Ndsl D6Nds6 Fabpl

Cpa plusmid cDNA-CPA-I, cDNA-CPA-II, cDNA-CPA-III DNA segment, Chr 6 pYdl-1 DNA segment, Chr 6, Lehrach-1 B1 SINE (CCTT) 3 DNA segment, Chr 6, Munich Univ-1 L10 DNA segment, Chr 6, Nuffield Dept ofSurg-1 MMDRF3 (micr~at) " (microsat) DNA segment, Chr 6, Nuffield Dept ofStmg-6 MMGSU1 (micresat) fatty acid binding protein, liver [R] Fabpl eDNA

+ + + + + +

Refereocee

Kimura Ki m u r a

Genomics 1989; 5:375 Nuel Acid Res 1989; 1713298 J Biol Chem 1990; 265:14432 tel:Craig, Gene 1991, 100:163 ref:Dernoncourt, Genomies 1991; 1111167 ref.'Stahl, Mol Cell Biol 1992; 1211179 Genomics 1990; 8:155 Genomics 1990; 8:155 DNA & Cell Biol 1990; 9:771 PNAS 1990; 87:9838 PNAS 1990; 87:9838 Somatic Cell Mol Genet 1987; 13:179 Somatic Cell Mol Genet 1987; 13:179 E u r J Biochem 1987; 168:515 Eur J Biochem 1987; 168:515

Frankel Frankel Frankel Frankel Frankel Frankel Frankel Frankel Ringuette Ringuette co:Ringuette Chamberlin Kinloch co:JA Todd co:SH Hughes (NCI) co:NG Copeland Tokunaga Peter Peter co:D Cleveland Kim Kim Ikawa colT Yamamoto Storm Regnier co:S Morse co:DB Farber co:TJ Jentsch co:TJ Jentsch Liau Schmidt Liau Schmidt Friedman Schmidt Myers Schnieke co:F Ramirez co:M Koch Quinto colW Rutter co:W Rutter Friedman co:JH Friedman co:JH Friedman Reynolds Reynolds Reynolds George Cox Klobeck co:JA Todd co:JA Todd co:JA Todd Sweetser co:J Cordon

J ViroI 1989; 63:1763 Mamm Genome 1992; 2:110 J Virol 1989; 6311763 J Virol 1989; 6311763 J Virol 1989; 63:1763 Genetics 1990; 124:221 J Virol 1989; 63:1763 Mamm Genome 1992; 2:110 PNAS 1986; 83:4341 Devel Biol 1988; 127:287 refiLunsford, Genomics 1990; 6:184 Devel Biol 1989; 131:207 Nucl Acid Res 1989; 1712861 ref:Aitman, Mamm Genome 1991; 1:206 refiJustice, Genetics 1990; 125:855 ref:Moore, Genomics 1991; 12:388 Mol Cell Biol 1988; 8:3929 J Mol Biol 1988; 203:665 J Mol Biol 1988; 203:665 ref:Rienhoff, Mol Cell Biol 1988; 8:3710 Mol Cell Biol 1989; 9:1875 Somatic Cell Mol Genet 1990; 161287 Mol Cell Biol 1988; 8:2651 refl Justice, Genetics 1990; 1251855 Oncogene 1990; 5:345 J Virology 1989; 63:3678 refiNorman, Genomics 1991; 9:147 ref:Danciger, Genomics 1992; 12:688 ref:Steinmeyer, Nature 1991; 354:304 ref:Steinmeyer, Nature 1991; 354:304 J Biol Chem 1986; 261:11362 Nature 1985; 3141286 J Biol Chem 1986; 261:11362 Nature 1985; 314:286 Genomics 1991; 11:1054 J Biol Chem 1984; 259:7411 PNAS 1981; 78:3516 Nature 1983; 304.'315 ref:Sundaresan, Sore Cell Mol Gen1989; 15:471 refiSteinmeyer, Nature 1991; 354:304 PNAS 1982; 79:31 ref:Norman, Genomics 1991; 9:147 ref:Buean, EMOB J 1986; 5:2899 Genonfics 1991; 1111054 ref:Steinmeyer, Nature 1991; 354:304 ref:Boyle, Genomics 1992; 12:106 J Biol Chem 1989; 265:20094 J Biol Chem 1989; 265:20094 J Biol Chem 1989; 265:20094 Nucl Acid Res 1984; 12:2731 Genomics 1991; I0:375 Nucl Acid Res 1988; 16:7190 rel2Hearne, Mamm Genome 1991; 1:273 refiMontagutelli, Mamm Genome 1991; 1:255 refiMontagutelli, Mamm Genome 1991; 1:255 J Biol Chem 1987; 262116060 ref:Norman, Genomics 1991; 9:147

Fet Miyazaki Miyazaki co:DT Denhardt co:P Borst,A Vinken colA VanderBliek Bach Bach Gonzalez Kuo Kuo Krasnewich Krasnewich

C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

336 Table 3. Continued. Chr S y m ~ a

6 6 6

Fgf-6

LocusName

Probeb

RFLV c Contactd

fibroblast growth factor-6

cos m13.1,m13.2,FS3,p450 deLapeyriere SB probe + deLapeyriere Fth-rs2 ferritin,heavy chain related sequence 2 pMHFA1 Yachou Gapd g]yceraldehyde-3-phosphate dehydrogenase [H]GAPDH Ingvarsson [H] pHcGAP co:ATCC [C] pGAPDH co:D Bentley Glut~3 glucose transporter protein-3, brain [H] Glut-3 eDNA Kayano Glut-3 PCR (fr Glut-3 eDNA) + co:A Schultz Glut-3 eDNA Nagamatsu Gnb-3 guanine nueleotide binding protein-~3 [H] B3R + co:DB Farber Hmgi-rs2 high mobility group protein I related seq-2 HGMI eDNA + Johnson hoJ~'g hotfoot (transgene) clones 2.6, 2.63, 2.1, BP1 Gordon Hox- 1 homeo bex-1 cluster cosl, cos2, cos3 Dubeule Hox-1 genomic Odenwald Hox-l.1 homeo box-l, gene 1 clones B21 Kessel p577 Bucan kin6, m6-12 Colberg-Poley km6, kin20, k m l Colberg-Poley pm6A3', pm6A5', pm6A Puschel Hox-1 genomic Odenwald pHoxl-B2.8 + co:RB Palmiter Hox-l.2 homeo box-l, gene 2 kin6, km5, k m l 2 Colberg-Poley Km6, km20, k m l Colberg-Poley kin5, kin12 Colberg-Poley m5 + Bucan co81 Dubeule Hoxol genomic Odenwald Hox- 1.3 borneo box-l, gene 3 kin5, ~.m2, %m12, k m l Colberg-Poley cKmb-1, Hox-1 genomic Odenwald clone A1 Fibi cosl Duboule p576 + co:BA Mock Hox-l.4 homeo box-l, gene 4 pHBT-1, HBT-1 Wolgemuth p2181-B2-4a Wolgemuth + Buean cosl Dubeule MH-3 Rubin Hox-1 genomic Odenwald Hox-l.5 homeo box-l, gene 5 coal, cos2, cos3 Dubeule pMod0,pG 10HBB,pG 10H BA Fainsod kJVIo-10, pMo-1O McGinnis pMo- 10 + co:McGinnis " + Mock kMo-10, pG10-UPA Rabin Hox- 1.6 homeo box-l, gene 6 am2, cas3 Duboule Hox- 1.7 homeo box-l, gene 7 MH-1G33b, Hox-l.7 eDNA Rubin MH-1G5 + Rubin Hox-l.8 homeobox-1, gene 8 clone 61h + Singh Hox-l.9 homeobox-1, gene 9 done 20h + Singh Hox-l.ll homeobox-1, gene 11 Hox-1.11 c D N A co:R Krumlauf Iapp islet amyloid polypeptide lapp e D N A Nisbi Igk immunoglobulin ~cgene complex px':~ Schuler LX1X 27'b' Schiff + Eicher M21-F2 Selsing K~ Kelley Igk-T84.66 M8 Neumaier Igk-C immunoglobulin ~ chain constant region MEMJC2 co:P Leder pRBJCk, pABkll, pHBCk Lewis pRBCk Alt pI'IBCk Vasmel Ck probe co:P Tucker K41C, K41(V+C) Swan K41(V+C) [=pBR322-K41] Seidman 149KC-2, EC-5, Seidman 41KC-21, pCR1-K149 Seidman M167VL, Spl01 co:Storb pECk + co:M Weigert + co:M Weigert + pLT31 Igk-C genomic pRx2-7 K~ K~ K~

K~

Azen eo:J Stafford eo:R Wall co:M Reth Kelley

Refemmee

Oncogene 1990; 5"823 Oneogene 1990; 5:823 Genomics 1991; 9:204 Oncogene 1988; 3:679 ref:Helaakoski, J Biol Chem 1990; 265:11413 ref:Rienhoff, Mol Cell Biol 1988; 8:3710 J Biol Chem 1988; 263:15245 ref:Hogan, Development 1991; 113:363 J Biol Chem 1992; 267:467 ref:Danciger, Genoraics 1992; 12:688 Genomics 1992; 12:503 Devel Biol 1990; 137:349 EMBO J 1986; 5:1973 Genes & Devel 1987; 1:482 PNAS1987; 84:5306 EMBOJ 1986;5:2899 Nature 1985;314:713 Cell 1985; 43:39 Development1990; 108:435 Genes& Devel 1987; 1:482 ref:Steinmeyer,Nature 1991; 354:304 Nature 1985;314:713 Cell 1985; 43:39 Cell 1985; 43:39 F_~MBOJ 1986; 5:~99 EMBO J 1986; 5:1973 Genes & Devel 1987; 1:482 Cell 1985; 43:39 Genes & Devel 1987; 1:482 Development 1988; 102:349 EMBO J 1986; 5:1973 ref:Siracusa, Genomics 1991; 10:313 EMBO J 1986; 5:1229 PNAS 1987; 84:5813 EMBO J 1986; 5:2899 EMBO J 1986; 5:1973 Science 1986; 233:663 Genes & Devel 1987; 1:482 EMBO J 1986; 5:1973 Devel Biol 1987; 124:125 Cell 1984; 38:675 ref:Moen, M a m m Genome 1991; 1:217 Genetics 1987; 116:607 PNAS 1986; 83:9104 EMBO J 1986; 5:1973 Mol Cell Biol 1987; 7:3836 Mol Cell Biol 1987; 7:3836 PNAS 1991; 88:10706 PNAS 1991; 88:10706 tel:Hunt, Nature 1991; 353:861 PNAS 1989; 86:5738 EMBO J 1988; 5:2139 EMBO J 1983; 2:1771 Genetics 1990; 125:431 Cell 1981; 25:47 Mo] Cell Biol 1985; 5:1660 Cane Res 1990; 50:2128 ref:Lewis, Cell 1982; 30:807 Cell 1982; 30:807 Cell 1981; 27:381 Leukemia 1987; 1:155 re~Goldrick, J Exp Med 1985; 162:713 PNAS 1979; 76:2735 Nature 1978; 276:790 Nature 1978; 276:790 Nature 1978; 276:790 ref:Selsing, Cell 1981; 25:47 ref:D'Hoostelaere, Immunogenet 1985; 22:227 ref:D'Hoostelaere, Curt Top Microbiol Immunol 1988; 137:116 Genomics 1989; 5:415 ref:Stafford, Nature 1983; 306:77 ref:Lee, J Exp Med 1984; 160:905 ref:Muller, Eur J Immunol 1990; 20:1409 Mol Cell Biol 1985; 5:1660 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

337

Table 3. Continued. Chr Symbola

6

Igk-C

6

Igk-J

LocusName

~

immunoglobulin z chain constant region pK(ll)~4 pV167Ck immunoglobulin ~ chain J region Jtcspecificprobe Jzl-J~5 Nk pECk

RFLVc Canta~

Schibler co:U Storb Boyd Yang Mucenski + co:C Thomas + co:K Huppi + co:M Weigert +

6 6 6

MEMJC2, pJ2/3 pRH5', pH5', pHJk, pRI-JH, pRBJCk Spl01 EC-5, 41KC-21 K41(V+C), pCR1-K149 pRx2-7, dk K~ K~ pK(11)24 imrnunoglobulin ~, recombining segment M315-rsl Igk-rs pRSB 1"8 pRxR- 1, pRxB-6 "Igk-Rx" between Igk-C and Igk-rs, includes 3' enhancer; homology 79% with human pRxH-1, pRxB-5 3' to Igk-rs, between Igk-C and Igk-rs immunoglobulin ~ chain variable region EM3.C58-7, EM3.BALB-1 Igk-V EM3.C58-6, EM3.C58-10 pK(ll)24 pT1 + pV167Ck Igk-genomic,embryonic K2 K41(V+C) K41(V+C) [=pBR322-K41] Igk-VArsA immunoglobulin ~, VArsA 5' ArsA + Igk-V1 immunoglobulin ~ variable chain (Vl) T105 + +

Azen co:P Leder Lewis Lewis Selsing Seidman Seidman eo:M Reth Kelley Sehibler Siminovitch Durdik eo:M Reth eo:M Reth co:M Reth Boyd Boyd Schibler co:Zachau eo:H Zachau co:U Storb co:T Honjo Swan Seidman co:PD Gottlieb Gibson co:D Gibson

eo:D Gibson Dzierzak Bailey co:DM Gibson Dzierzak Dzierzak Dzierzak Dzierzak Dzierzak Dzierzak Dzierzak Kofler co:DM Gibson co:DM Gibson Kofler eo:S Cory D'Hoostelaere Cory + eo:S Cory

Igk-ViE Igk-VIF Igk-V2 Igk-V4

LX1X27 PPvl01 Igk-M460 eDNA, Igk-D35 eDNA, Igk-LB8 eDNA, Igk-2AB5 eDNA, Igk-ID29 eDNA, Igk-ID18 eDNA, Igk-M467 eDNA, IGELb4 immunoglobulin ~, V1 pseudogene (BALB/c) EB-43, BA43 immunoglobulin ~, V1 pseudogene (BALB/c) EB-14, Danl4 inmmnoglobulin ~ variable chain ( V 2 ) BXW-DNA14 immunoglobulin r variable chain ( V 4 ) pH76k10 (=H76K10)

immunoglobulin ~ variable chain (V5) immunoglobulin ~ variable chain (V8)

MRL-DNA22 PC2154 M603K2

+

Igk-V5 Igk-V8

immunoglobulin ~r variable chain (V9)

" (=pM603k2) pk13917 IGELa2 MOPC41 5'FL

co:S Cory co:Riley Kofler co:C Queen + D'Hoostelaere + co:C Queen

Igk-V9

M41 BXW-DNA16 pLT31 pLTll, pLT12 41KC-21 pM41kl clone 42.9.5

Kofler Kelley + D'Hoostelaere + co:S Cory

+

Kofler co:J Stafford co:C Queen Seidman co:NM Gough co:K Kasturi

Refemet~ ~

Cell 1978; 15:1495 ref:Gritzmaeher, J Immunol 1987; 138:324 Irnmtmogenetics 1986; 24:150 Immunogenet 1987; 25:222 Mol Cell Biol 1986; 6:4236 ref:deLapeyriere, Oncogene 1990; 5:823 ref:Norman, Genomics 1991; 9:147 ref:D'Hoostelaere, Curr Top Microbiol Immunol 1988; 137:116 Genomics 1989; 5:415 ref:Lewis, Cell 1982; 30:807 Cell 1982; 30:807 Cell 1982; 30:807 Cell 1981; 25:47 Nature 1978; 276:790 Nature 1978; 276:790 ref:Muller, Eur J Immunol 1990; 20:1409 Mol Cell Biol 1985; 5:1660 Cell 1978; 15:1495 Nucl Acid Res 1987; 15:2699 PNAS 1985; 307:749 ref:Muller, Eur J Immunol 1990; 20:1409 ref:Muller, Eur J Immuno] 1990; 20:1409 ref:Muller, Eur J Immunol 1990; 20:1409 PNAS 1986; 83:9134 PNAS 1986; 83.9134 Cell 1978; 15:1495 Nucl Acid Res 1980; 8:1693 ref:Bucan, EMBO J 1986; 5:2899 refiGritzmacher, J Immunol 1987; 138:324 ref:.'Kataoka, J Biol Chem 1982; 257:277 PNAS 1979; 76:2735 Nature 1978; 276:790 ref:Kim, Immunogenetics 1991; 34:231 ref: Moynet, J Immtmol 1985; 135:727 ref:D'Hoostelaere, Curt Top Microbiol Immunol 1988;137:116 ref:Dzierzak, J Immunol 1986; 136:1864 J Exp Med 1985; 162:1494 Eur J Immunol 1991; 21.959 ref:Chung, Immunogenetics 1991; 34:313 J Exp Med 1985; 162:1494 J Exp Med 1985; 162:1494 J Exp Meal 1985; 162:1494 J Exp Med 1985; 162:1494 J Exp Med 1985; 162:1494 J Exp Med 1985; 162:1494 J Exp Mod 1985; 162:1494 Mol Immunol 1992; 29:161 ref:Chung, Immunogenetics 1991; 34:313 ref:Chung, Immtmogenetics 1991; 34:313 Immunogenetics 1989; 29:65 ref:Gough, Biochemistry 1980; 19:2702 Immunogeneties 1986; 23:260 J Mol App Genet; 1981 1:103 ref:D'Hoostelaere, Curr Top Microbiol Immtmol 1988; 137:116 Immunogenetics 1989; 29:65 Mol Cell Biol 1985; 5:1660 Immunogenetics 1986; 23:260 ref:D'Hoostelaere, Curt Top Microbiol Immunol 1988; 137:116 ref: Gough, Biochemistry 1980; 19:2072 refiKofler, Immunogenetics 1989; 29:65 Mol Immunol 1992; 29:161 ref.- Stafford, Nature 1983; 306:77 Immunogenetics 1986; 23:260 ref: D'Hoostelaere, Curr Top ~[icrobiol Immunol 1988; 137:116 Immunogenetics 1989; 29:65 refiStafford, Nature 1983; 306:77 ref:Queen, Cell 1983; 33:741 Nature 1978; 276:790 ref:Gough, Biochemistry 1980; 19:2702 ref:Kaushik, Eur J Immunol 1991; 21:827 C o n t i n u e d on next p a g e

338

J.T. Eppig: Clones and Probes

Table 3. Continued. Symbola

6

Igk-V10

LocusName

Probeb

RFLVc C a n ~ "d

immunoglobulin ~: variable chain (V10) +

co:M Shapiro co:M Shapoiro

Seldin Kelley + co:Kelley D'Hooatelaere 33865'V pM173k14 co:NM Geugh AKRga2, AJ1, co:PD Gottlieb PERU7bl, PERU14al co:PD Gottlieb AKR51al, AKR7al, co:PD Gottlieb AKR12al, AKRSal, AJ2, co:PD Gottlieb PERU6al co:PD Gottlieb (=PC66S4) co:R Perry + D'Hoostelaere § co:R Perry d-

" (=PC3386) p3386NX

Igk-V10.1 Igk-Vl0.2

6

lgk-V11

6

pABXII Igk-V12/13 immunoglobulin ~cvariable chain (V12/13) K 2 A pBC2-5(4.8)

6 6 6 6

Igk-Vl4 immunoglobulin ~cvariable chain (V14) Igk-V15 immunoglobulin ~ variable chain (V15) Igk-V15/19 immunoglohulin ~: variable chain (V15/19) Igk-V19 immunoglobulin *: variable chain (V19)

6

Igk-V20

immunoglobulin *c variable chain (V20)

6

Igk-V21

immunoglobulin ~c variable chain (V21)

immunoglobulin *: variable chain (VII)

pg(V-TNP)b pM21kl pVkMPCI I

pK(11)24-S

+ +

+

co:Hawley Gough + co:Kelley + co:A Lawler

CS.5Vk probe Vk20trp35 genomic B61K16 " (=pB61k21)

+

+ + +

[V21A and V21G from RALB]

Vk21A Vk21 Ag8.653nf XGH6

Shefner Xu + D"Hoostelaere co:S Cory Cory Weiss co:S Cory

+

Epstein co:S Cory Kofler Heinrich co:Heinrich frA Lawler

+

Gough co:Lavoie co:T Lavoie

4-

6

Igk-V22

immunoglobulin z variable chain (V22)

pVTIS-S

6

Igk-V23

immunoglobulin r variable chain (V23)

r~107k4 HyHEL10

6

Igk-V24

immunoglobu]in ~ variable chain (V24)

MRL/n-RF33B M167VL

+ % +

Kofler ce:Storb D'Hoostelaere co:R Joho

pES201, Kd-DI, pED320, M511-A1 MRL-RF28 + Igk-VSera p9(35) p9(35) or Igk-VSerb Igk-VSerc, Igk-VSerd Igk-VSerb genomic + Ch30.2 + EM3.C58-5, EM3.C58-7, EM3.C58-10, EM3.BALB- 1 Igk-VkSer specific probe +

6

]gk-V28

immunoglobulin ~: variable chain (V28)

6 6 6

Igk-V32 Igk-V33 Igk-VRf

immunoglobulin r variable chain (V32) immunoglobulin ~ variable chain (V33) immunoglobulin ",r variable chain (VRF)

6

Igk-V9-26

Vk32 eDNA Vk33 eDNA MRL-RF24 VkRF cDNA immunoglobulin ~: variable chain (V9-26) pC9-26

6

Ins-1

insulin-1 or insulin pseudogene

Selsing Selsing Kofler Ponath Goldrick Ponath Ponath Ponath Boyd Boyd Boyd Goldrick Ponath § Yang + D'Hoostelaere + D'Hoostelaere + Kofler D'Hoostelaere + co:Shapiro

[H] phins214 §

(from NON mice)

Lewis co:Nishioka co:A Lawler

pMI-I kNins-I

Bell Saunders Wentworth Sawa

Refo~ncee

ref:D'Hoostelaere,I mmunogen 1986;23:260 ref:D'Hoostelaere, Curt Top Microbiol Immunol 1988;137:116 Immunogenetics 1988; 27:396 Mol Cell Biol 1985; 5:1660 ref:Kofler, Immunogeaetics 1989; 29:65 J Immunol 1990; 145:2706 ref:Gough, Biochemistry 1980; 19:2702 ref:Kim, Immunogenetics 1991; 34:231 ref:Kim, Immunogenetics 1991; 34:231 ref:Kim, Immunogenetics 1991; 34:231 ref:Kim, Immunogenetics 1991; 34:231 ref:Kim, Immunogenetics 1991; 34:231 ref:Kelley, Mol Cell Biol 1985; 5:1660 Immunogenetics 1986; 23:260 ref:D'Hoostelaere, Curr Top Microbiol Immunol 1988;137:116 Cell 1982; 30:807 ref:Kofler, Immunogenetics 1989; 29:65 ref:D'Hoostelaere, Curr Top Microbiol Immunal 1988; 137:116 ref:Kofler, Immunogenetics 1989; 29:65 Biochemistry 1980; 19:2072 ret~Kofler, Immunogenetics 1989; 29:65 ref: D'Hoostelaere, Curt Top Microbiol Immunol 1988; 137:116 J Immunol 1990; 145:1609 Nud Acid Res 1990; 18:1912 Immunogenetics 1986; 23:260 ref:Gough, Biochemistry 1980; 19:2072 J Mol App Genet 1981 1:103 J Immunogenet 1989; 16:283 ref:D'Hoostelaere, Curr Top Microbiol Immuaol 1988; 137:116 J Exp Med 1985; 161:1219 ref:Robbins, J Virol 1986; 57:709 Immunogenetics 1989; 29:65 J Exp Med 1984; 159:417 ref:Alanen, Eur J Immunol 1989; 19:1961 ref:D'Hoostelaere, Curr Top Microbiol Immunol 1988; 137:116 Biochemistry 1980; 19:2072 ref:Smith-Gill, J Mol Biol 1987; 194:713 ref:D'Hoostelaere, Curr Top Microbiol Immunol 1988; 137:116 Immunogenetics 1989; 29:65 ref:Selsing, Cell 1981; 25:47 Immunogenetics 1986; 23:260 ref:D'Hoostelaere, Curt Top Microbiol Immunol 1988;137:116 Cell 1981; 25:47 Cell 1981; 25:47 Immunogenetics 1989; 29:65 Immunogenetics 1989; 29:249 J Exp Med 1985; 162:713 Immunogenetics 1989; 29:249 Immunogenetics 1989; 29:249 Immunogenetics 1989; 29:249 Immunogenetics 1986; 24:150 PNAS 1986; 83:9134 PNA8 1986; 83:9134 J Exp Med 1985; 162:713 Immtmogenetics 1989; 29:249 Immunogenet 1987; 25:222 J Immunol 1990; 145:2706 J Immunol 1990; 145:2706 Immunogenetics 1989; 29:65 J Immtmol 1990; 145:2706 ref:D'Hoostelaere, Curt Top Microbiol Immunol 1988; 137:116 Diabetes 1984; 33:176 Genomics 1990; 8:525 J Mol Evol 1986; 23:305 J Mol Endocrinol 1990; 5:61 C o n t i n u e d on next p a g e

339

J.T. Eppig: Clones and Probes Table 3. Continued. Cbr ~ a

6

Int-41

6

Kap

6

Kras-2

Locus Name

Probeb

pBk41, pAS311 Int-41 genomic frag kidney androgen regulated protein pKAPll KAP29L, DAP19S, KAP19B, KAP10 Kirsten rat sarcoma oncogene-2, expressed clone 4, [V] KBE-2 [V] KBE-2 pHiHi3

RFLVc Con~tc~

MMTV integration site-41

+

§ +

Ldh-2

lactate dehydregenase-2, B chain

Ly-2

lymphocyte antigen-2 [=human CDSa]

eYKi2, pVPk4, VPkl pKMSV + kMKN-142,:k~IKT-142 pY413 [H] pSW-11-1 [HI Kras cDNA + subclone of KCC7 + Kras-2 probe + mB188, mB162, mB168 roB162-1, LDH/B3' kLy-2-B, ~.Ly-2-D, ~.Ly-2-F CD8a'

(Ly-2.2) (Ly-2.1) 6

Ly-3

lymphocyte antigen-3 [=human CD8b]

6

Ly-6

lymphocyte antigen-6 (Ly-3.2 allele)

(Ly-3.1) 6

Ly-4

L3T4 T cell differentiation antigen [=human CD4]

6

Ly-49

lymphocyte antigen-49

6

Met

met proto oncogene

6

Mglap

matrix T-carboxyglutamate (gla) protein

6

"Mns-6"

minor satellite Chr 6 (centromeric)

6 6 6 6 6 6 6

Mov-1 Moloney leukemia virus-1 Ms6-4 minisatellite 6-4 "Ms3-1-9-PI" minisatellite 3-1-9-P1 ( h u m a n D3S45) '~vls3-2-8-Pl" minisatellite 3-2-8-P1 ( h u m a n D3S45) '~Ms3-3-8-Pl" minisatellite 3-3-8-P1 (human D3S45) "Ms7d-7-P2" minisatellite 7-1-7-P2 (human RB1) "Ms7-2-16-P2" minisatellite 7-2-16-P2 (human RB1)

CDSa cDNA pWeLyt-2 Ly-2 genomic ~:Ly2-7, ~cLy2-10, ~cLy2-2 ~cLy2-5, Ly-2 genornic ~.Ly2.1 CAK411, CAK292 cosLy-3-17, ~.cLy-3-3 ~cLy-3-5 ~cLy-3-6 + [R] pX9.5 RCCT134 + MMSLYT3A1 (microsat)+ (microsat) + kLY3C-23 + ~.LY3C-24 LGC2A, pLGC2 CAK812, CAK361, CAK302 L20131 p3C, L3T4.25 pcL3T4-C7 + (=Ly-4 cDNA) + pL3T4B Ly-4 PCR]RT MMCD46 (microsat) + (microsat) + pAl .3 + [H] pMet-1 " + [HJ pMet G + " + [H] pMetD + Met cDNA Met cDNA-1 + []-I] Met probe pUC5FL (Met cDNA der)+ [H] pmetl/tpr " Mglap cDNA MC-20 pMR150 Mo-MuLV cDNA [H] probes 33.6 pEFD134.7 pEFD134.7 pEFD134.7 p68RS2.0 proSRS2.0

+ + + + + +

Garcia eo:H Diggelmann Watson co:Catterall co:Catterall co:EM Scolnick co:K Noonan co:EM Scolniek Sakaguehi Ryan Azen George George co:E Chang Guerrero Cahilly ATCC 41027 co:ATCC co:D Stoler eo:Oncor P2145 co:S S-L Li co:S S-L Li Gorman eo:L Herzenberg co:Littman co:G Evans Liaw Zamoyska Zamoyska Liaw Youn Gorman Gorman Gorman Johnson Panaccio co:JA Todd co:JA Todd Nakauchi Nakayama Nakauchi Nakayama Youn Nakayama Littman Tourvielle Seldin Goodwin Maddon Mori eo:JA Todd co:JA Todd Yokoyama Yokoyama co:Dean co:Dean co: Dean co: Cooper co:F Ramirez lyer co:G vandeWoude eo:Oncor P2210 co:TE Kmiecik Dean co:M Dean Johnson Ikeda Voliva co:VM C h a p m a n co:ND Hastie Breindl Jeffreys Julier Julier Juliet co:T Dryja co:T Dryja

Referencee

EMBO J 1986; 5:127 ref:deLapeyriere, Oncogene 1990; 5:823 Ann NY Acad Sci 1984; 438:101 ref:Niu, DNA & Cell Biol 1991; 10:41 rel~Niu, DNA & Cell Biol 1991; 10:41 tel:Ellis, Nature 1981; 292:506 ref:Fukumote, Som Cell Mol Gen 1986; 12:611 ref:Ellis, Nature 1981; 292:506 PNAS 1984; 81:525 Nucl Acid Res 1986; 14:9222 Genomics 1989; 5:415 N u d Acid Res 1984; 12:2731 Nucl Acid Rss 1984; 12:2731 ref:Robbins, J Virol 1986; 57:709 Science 1984; 225:1159 Cytogenet Cell Genet 1985; 39:140 Martin-DeLeon,Som Cell Mol Gen 1988;14:205 ref:deLapeyriere, Oncogene 1990; 5:823 ref:Elliott, Genomics 1990; 6:635 ref:Danciger, Genomics 1992; 12:688 ref:Hiraoka, Eur J Biochem 1990; 189:215 ref:Thomas, Development 1990; 109:483 J Immunol 1988; 140:3646 refiTurner, Cell 1990; 60:755 ref:Turner, Cell 1990; 60:755 ref:BoyIe, Genomies 1992; 12:196 J Immtmo11986; 137:1037 Cell 1985; 43:153 Cell 1985; 43:153 J Immtmo11986; 137:1037 Immunogeneics 1988; 28:345 J Immunol 1988; 140:3646 J Immtmo11988; 140:3646 J Immtmo11988; 140:3646 Nature 1986; 323:74 Immunol Cell Biol 1989; 67:.429 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 PNAS 1987; 84:4210 J Immuno11989; 142:2540 PNAS 1987; 84:4210 J Immuno11989; 142:2540 Immunogenetics 1988; 28:353 J Immunol 1989; 142:2540 Nature 1987; 325:453 Science 1986; 234:610 Immunogenetics 1988; 27:396 Mol Cell Biol 1991; 11:3020 PNAS 1987; 84:9155 BBRC 1992; 182:527 ref:Hearne, M a m m Genome 1991; 1:273 rei~Montagutelli, M a m m Genome 1991; 1:255 J Immuno11989; 143:1379 J Immunol 1990; 145:2353 Mol Cell Biol 1987; 7:921 Genomics 1987; 1:167 refi Sweet, Nucl Acid Res 1988; 16:8745 res Sweet, Nucl Acid Res 1989; 17:4907 ref:Steinmeyer, Nature 1991; 354:304 Cell Growth & Differentiation 1990; 1:87 refiPriedman, Genomics 1991; 11:1054 ref:Danciger, Genomics 1992; 12:688 ref:Siracusa, Genetics 1991; 127:169 Mol Ceil Biol 1987; 7:921 ref:Park, Cell 1986; 45:895 Genomics 1991; 11:770 J Bone Mineral Res 1991; 6:1013 Nucl Acid Res 1983; 11:8847 ref.'Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1983; 11:6965 PNAS 1979; 76:1938 Nucl Acid Res 1987; 15:2823 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 rofiJulier, PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4585 Continued on next page

340

J.T. Eppig: Clones and Probes

Table 3. Continued. Chr Symbda

6 6

~

Name

~Ms7-1-4-Pl" minisatellite 7-1-4-P1 (human RB1) Mtv-8 m a m m a r y tumor virus locus-8

Probeb

p68RS2.0 MMTV eDNA MTV-LTR MMTV(C3H)LTR MMTV eDNA or DNA GR-40 Mtv8-5'C, Mtv8-3'C

6 6 6 6 6

Mtv-23 Mtv-29 Mtv-33 Mtv-34 Myk-103

m a m m a r y tumor virus locus-23 m a m m a r y tumor virus locus-29 m a m m a r y tumor virus locus-33 m a m m a r y tumor virus locus-34 sequence flanking transgenic insert

Npy

neuropolypeptide Y

Ntf-3

neuroptrophin-3

Odc-rs5

ornithine decarboxylase related seq-5

RFLVc Con~:td

+ + + + + + + + +

Mtv8-5', Mtv8-3' MMTV (C3H) probe MMTV8-29, MMTV8-21 MMTV 8-29 + MMTV 8-21 + MMTV8-21,MMTV8-29 MMTV env probe + kGRT25 pTZ18R-ORF + MMTVS-21,MMTVS-29 + MMTV8-21,MMTVS-29 + MMTV8-21 + MMTV8-21 + ~%5,).2, ~21, k41, Bgll.6 probe + + EN probe + JR] Npy-5 + [H] NT3

Pim- l r s l Pot

pMK217 + pCR6 (pDOC934 derived) " + Otf-3 related sequence-5 3' Off-3 eDNA + 5' Otf-3 eDNA + Purkinje cell protein-1 PCD6, PCD603~5 PCD6037, PCD6035A PCR(from PCD6035 seq) + Pim-1 oncogene related sequence-1 prc~B NADPH-cytochrome P-450 oxidoreductase JR] pOR-7

Prp

proline-rich protein

Otf3-rs5 Pep-1

B-subfamily 6

Pthlh

parathyroid hormone like peptide

6

Raf-1

routine sarcoma 3611 oncogene-1

6

Ret

Ret proto-oncogene

M14, M56, M2 MC 16, MC22 pMP1, pUMP125, pUMP40 pMP4, pUMP39, pUMP42 [R] pRP33 + + MMPRPMPB (microsat)+ (microsat)+ 3B, pHD1, pEC1, MP4, la28, pUMP125 p46, p47 [R]rPLPm7-2, [R]rPLPml0 [R] rPLPm9 ~.-7, k-4B p171 + v-raf 3611-MSV, V-rafXB 3611-MSV + V-raIXB (= v-raf) Raf-1 eDNA + [H] pHEI p627 + Raf-1 probe + pSV2retT IV] Pet +

6

Rho

rhodopsin

RoM2.1 +

co:T Dryja Michalides Michalides co:JE Majors co:J Ball, J Majors co:Hynes co:N Hynes Peters co:G Peters Peters co: Varmus Majors Either Eicher Lee Yang co:TG F a n n i n g co:JE Majors Lee Lee co:JE Majors co:JE Majors Wilki e Wilkie co:LC Tsui Wilkie Allen co:J Allen Rosenthal Ozcelik 1-Elliott,Berger Rheaume co:FG Berger Siracusa Siracusa Nordquist Nordquist Norman Hilkens Gonzales Simmons Ann An n co:DM Carlson co:DM Carlson co: DM Carlson co:DM Carlson co:JA Todd co:JA Todd co:CJ McDonald co:CJ McDonald co:CJ McDonald Yasuda Hendy Mangin co:U Rapp co:Muller Rapp Bucan Kozak co:U Rapp co:ATCC 41308 co:ATCC co:Oncor co:Oncor P2115 Takahashi Iwamoto Takahashi co:A Schultz Baeher co:W Baeher

Ixt20 + co:J N a t h a n s Opa eDNA Nir L2H2 co:GH Travis M2, M3, M4, )~VIO1, ~ I O 2 AI-Ubaidi :kMOPS1, pMOPS5 Lem

Referencee

ref:Julier, PNAS 1990; 87:4585 Virology 1985; 142:278 Virology 1985; 142:278 ref:Rabbins, J Virol 1986; 57:709 ref:MacInnes, Virology 1984; 132:12 ref:Hynes, PNAS 1981; 78:2038 ref:Robbins, J Virol 1986; 57:709 J Virol 1986; 59:535 ref:Dyson, Nature 1991; 349:531 J Virol 1986; 59:535 ref: Azen, Genomics 1989; 5:415 Nature 1981; 289:253 Genetics 1990; 125:431 Genetics 1990; 125:431 J Virol 1990; 64:4568 Immunogenet 1987; 25:222 refiPathak, JNCI 1987; 78:327 ref:Pullen, J Exp Med 1992; 175:41 J Virol 1990; 64:4568 J Virol 1990; 64:4568 rof:Siracusa, Genetics 1991; 127:169 ref:Siracusa, Genetics 1991; 127:169 Mol Cell Biol 1987; 7:1646 Mol Cell Biol 1987; 7:1646 ref:Steinmeyer, Nature 1991; 354:304 Genes & Development 1991; 5:38 PNAS 1987; 84:2532 ref:Norman, Genomics 1991; 9:147 Neruon 1990; 4:767 Genomics 1991; 10:569 ref: Richards-Smith, MNL 1984; 71:46 Mol Endocrinol 1989; 3:1243 ref:Siracusa, Genetics 1991; 127:169 Genomics 1991; 10:313 Genomics 1991; 10:313 J Neur~ci 1988; 8:4780 J Neurosci 1988; 8:4780 Genomica 1991; 9:147 Somatic Cell Mol Genet 1986; 12:81 J Biol Chem 1982; 257:5962 J Biol Chem 1985; 260:515 J Biol Chem 1988; 263:10887 J Biol Chem 1988; 263:10887 ref'A Biol Chem 1985; 260:13471 ref'A Biol Chem 1985; 260:13471 ref: Azen, Genomics 1989; 5:415 ref:Frankel, M a m m Genome 1992; 2:110 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 ref:Rober~, Eur J Bioehem 1991; 202:969 ref:Roberta, Eur J Biochem 1991; 202:969 ref:Layfield, Eur J Biochem 1992; 204:591 Mol Endocrinol 1989; 3:518 Cytogenet Cell Genet 1990; 53:80 Gene 1990; 95:195 ref:Robbins, J Virol 1986; 57:709 ref:Rapp, PNAS 1983; 80:4218 PNAS 1983; 80:4218 EMBO J 1986; 5:2899 J Virol 1984; 49:297 ref:deLapeyriere, Oncogene 1990; 5:823 ref:Tailor, Cane Genet Cytogenet 1989; 40:89 ref:Elliott, Genomics 1990; 6:635 ref:Storm, Oncogene 1990; 5:345 ref:Danciger, Genomics 1992; 12:688 Oncogene 1988; 3:571 Oncogene 1990; 5:535 Mol Cell Biol 1987; 7:1378 ref:Hogan, Development 1991; 113:363 FEBS Left 1988; 238:253 ref:Elliott, Genomies 1990; 6:635 ref:Danciger, Genomica 1992; 12:688 Exp Eye Res 1990; 51:257 ref:Travis, Nature 1989; 338:70 J Bio] Chem 1990; 265:20563 Neuron 1991; 6:201 Continued on next p a g e

J.T. Eppig: Clones and Probes Table 3.

Continued.

Chr Symbola

Locus Name

6 6

Rn7s-6 Rpl32

7S RNA-6 ribosomal protein L32

6

Rpn-1

ribophorin- 1

6

Sftp-3

pulmonary surfactant apoprotein-3

6 6

Syb-1 Tcrb

synaptobrevin- 1 T cell receptor 13chain

6

Tcrb-D

T cell receptor 13 chain -D region

6

Tcrb-J

T cell receptor 13 chain-J region

6

341

Tcrb-J

T cell receptor [3 chain-J region

probeb

RFLVc Conlactd

pA6 + RPL32-3A, RPL32-4E, RPL32-4A, RPL32-SC, RPL32-5A, PRL32-6B, p3AR2.8, p3AH3.4, p3ARB3.7, p4AR3.5, p4ABI4.5,p4AR2.2 ,PL32/33 L32-I3 Sub~2 [H] Rpn-1 cDNA p16.2e + clone M2.1 [HI VP110-1 p4.1, CSp~.4 p4.1 + Tcrb probe + [HI TCRB probe + TM86 86T35 MMTCBVC1 (microsat) + 1.9.2, BW5147, 2B4,3H.25 pHDSll, 86T1 TCR-F5 -BETA MDA~ El, C5, LB2 D~I probe + D~2 probe + p2B4.71, 2B4.1, 2B4.9 p2B4.71 pHDSll probe 3 (= probe F) pUCJ2A (= probe F) " (=pUCJ~2, probe 3) + pUCJ1 (= pmbe B) M19DB2.HE (=probe E) TCR-F5 -BETA probe 6 + 11 SJL33, SJL73, ~ 4 TB3,TB21,TB12,TB2,AR1 1.9.2, BWS147,2B4, 3H.25 pHDSll, 86T1 MDA]3 El, C5, LB2 J15

6

Tcrb-C

T cell receptor 13 chain (constant)

pH:DSll " pDO~2 " " 5/10-20 D~ pDO]32

T22.10 pCh2 q31 RBI~6-17 (C]31 probe) C]32 specific 47.1J6.19, 46.1J6.19 1.1J6.19, 4.1J6.19 probe 4 (=probe G) C~ probe ( = probe D) 86C3

+ + +

+ + + +

+

Taylor Dudov Dudov Dudov Dudov Dudov Dudov co:K Dudov co:AB Pardee Barton Crimaudo co:NG Copeland Glasser Arch er Snodgrass co:M Steinmetz Friedmann co:A Puschel Hedrick Hedrick co:JA Todd co:RK Barth co:RK Barth Palmer Becker co:RK Barth Kotzin Kotzin Chien Bougueleret Bougueleret Saito Malissen Mucenski Mucenski Kotzin Klotz Mucenski Sin Palmer Epstein Epstein Behlke co:RK Barth co:Barth co:RK Barth co:RK Barth Becker co:RK Barth Snodgrass Vasmel Saito Saito Kotzin Born Yague Iwamoto co:Iwamoto Kotzin Kotzin Born Yague Lee Schuler Behlke co:A Traunecker Epstein Caccia Kotzin Malissen Malissen Malissen Sire Lee

Referencee

Immunogenetios 1985; 22:471 Cell 1984; 37:457 Cell 1984; 37:457 Cell 1984; 37:457 Cell 1984; 37:457 Cell 1984; 37:457 Cell 1984; 37:457 ref:Wiedemann, Sore Cell Mol Gen 1987;13:77 ref:Nikaido, Exp Cell Res 1991; 192:102 Cytogenet Cell Genet 1987; 46:577 EMBO J 1987; 6:75 ref:Moore, Genomics 1992; 12:388 J Biol Chem 1990; 265:21986 J Biol Chem 1990; 265:17267 Nature 1985; 313:592 ref:Bucan, EMBO J 1986; 5:2899 Genomics 1991; 11:1054 ref:Stelnmeyer, Nature 1991; 354:304 Nature 1984; 308:149 Nature 1984; 308:153 ref:Hearne, M a m m Genome 1991; 1:273 tel:Bar,h, Nature 1985; 316:517 ref:Barth, Nature 1985; 316:517 Nucl Acid Ros 1989; 17:2353 Nature 1985; 317:430 ref:Barth, Nature 1985; 316:517 Science 1985; 229:167 Science 1985; 229:167 Nature 1984; 309:322 Immunogenet~cs 1987; 26:304 Immunogenetios 1987; 26:304 Nature 1984; 309:757 Cell 1984; 37:1101 Mol Cell Biol 1986; 6:4236 J Virol 1988; 62:839 Science 1985; 229:167 Immunogenetios 1989; 29:191 Mol Cell Biol 1986; 6:4236 Nature 1984; 311:344 Nucl Acid Re~ 1989; 17:2353 J Exp Med 1985; 161:1219 J Exp Med 1985; 161:1219 PNAS 1986; 83:767 ref:Barth, Nature 1985; 316:517 refiBougueleret,Immtmogenet 1987;26:304 ref:Barth, Nature 1985; 316:517 ref:Barth, Nature 1985; 316:517 Nature 1985; 317:430 ref:Barth, Nature 1985; 316:517 Nature 1985; 313:592 Leukemia 1987;1:155 Nature 1984; 309:757 Nature 1984; 312:36 Science 1985; 229:167 PNAS 1985; 82:2925 Cell 1985; 42:81 J Exp Med 1987; 165:592 refi Nobuhara, Immunogenetic~ 1989; 30:405 Science 1985; 229:167 J Exp Med 1987; 165:1237 PNAS 1985; 82:2925 Cell 1985; 42:81 J Exp Med 1984; 160:905 EMBO J 1988; 5:2139 PNAS 1986; 83:767 refiVidard, Immunogenetics 1990; 32:27 J Exp Med 1985; 161:1219 Cell 1984; 37:1091 Science 1985; 229:167 Nature 1986; 319:28 Nature 1986; 319:28 Cell 1984; 37:1101 Cell 1985; 42:89 J Exp Meal 1984; 160:905 C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

342 Table 3. Continued. Chr Syml~a

6

Tcrb-C

Locus Name

T cell receptor 13 chain (constant)

Probeb

RFLVc Contact~1

86T5 +

6

Tcrb-V

T cell receptor [~ chain (variable) intergenie between Vb3.1 and Vb7 intergenie 3' to Vbl8 intergenie between Vb3.1 and Vb7 intergenic between Vbl and VbS.2 single copy between Vbl and Vb5.2

6

Tcrb-V1

single copy between Vbl7 and Vb3 Tcrb-variable (VI31 family)

pHDSll TCR-F5 -BETA Tcrb-C eDNA Tcrb-C.F6, Tcrb-5C.C7 Terb-B10, Terb-4.C3 PCR primers MTCB2DO, PCR MTCB1DO, MTBUP vB11,vB9,vB3,vB8,vB5 " pHDSll pwll cos El9, E40, pw2, pw20 cos G6 cos F 10 pwlO, pw8 pwl0 pN3 (3' end KpnI frag) Tcrb-AP15.2, Tcrb-V1.9.2 86T1 + + 1.9.2, BW5147 pUCV~I + V~I + V[$1 eDNA Vbl, Vbl.2

+

cos DS, D7, D10, C16, C47 cosmid D1A Vblb-PcR, Vbla-PCR + pUCJ1 (J~l)

6

Tcrb-V2

Tcrb-variable (V[32 family)

" (=pUCJ[31, probe 1) pUCV]52 V~2

+ + +

V~2 eDNA AR1 E1 6

Tcrb-V3

Tcrb-variable (V[~3 family)

Tcrb-C.F6, Tcrb-5C.C7 P

Tcrb-AN6.2, Tcrb-APll.2 Tcrb-AN14.4, Tcrh-Vll.5 Tcrb-2B4 pUCV~3 + V[k3 + + V[33 eDNA 2B4, 3H.25 p2B4.71, 2B4.1, 2B4.9, B.6 p2B4.71

6

Tcrb-V3.1 Tcrb-V3.2 Tcrb-V4

Terb-variable (V~4 family)

co8 D18, D6 cos BS, D18, D6 cos D15, D5, D7, D10 cosmid D1A TB3 pUCV~4 (=TI~3) V]~4 " V~4 eDNA

+ +

Hedrick Epstein Vasmel Lee Saito Palmer co:M Steinmetz Fink Fink co:PN Marche co:PN Marche Behlke Bougueleret Saito Chou Chou Chou Chou Chou Jouvin-Marche Jouvin-Marche Winoto Hedrick co:M Davis Seldin co:RK Barth K]otz Behlke co:DY Loh Behlke Behlke Bougueleret Chou co:E Lai Spinella Malissen Mucenski Kronenberg Mucenski Klotz Klotz Behlke Bougueleret co:DY Loh Behlke co:RK Barth co:Barth co:RK Barth Patten Winoto Fink Winoto Winoto Winoto Klotz Behlke Behlke co:DY Loh Behlke co:RK Barth Chien Bougueleret Bougueleret Chou Chou Chou co:E Lai co:RK Barth eo:Barth Klotz Behlke Bougueleret co:DY Loh Behlke

Refe~aacee

Nature 1984; 308:153 J Exp Med 1985; 161:1219 Leukemia 1987; 1:155 J Exp Med 1984; 160:905 Nature 1984; 309:757 Nucl Acid Re~ 1989; 17:2353 ref:Snodgra~, Nature 1985; 315:232 Nature 1986; 321:219 Nature 1986; 321:219 refiSix, J Exp Med 1991; 174:1263 refiSix, J Exp Med 1991; 174:1263 Science 1985; 229:566 Immunogenetics 1987; 26:304 Nature 1984; 309:757 Science 1987; 238:545 Science 1987; 238:545 Science 1987; 238:545 Science 1987; 238:545 Science 1987; 238:545 E u r J Immuno11989; 19:1921 E u r J Immunol 1989; 19:1921 Nature 1986; 324:679 Nature 1984; 308:153 ref:D'Hoostelaere, Immunogenet 1985; 22:277 Immunegenetice 1988; 27:396 ref:Barth, Nature 1985; 316:517 Immunogenetics 1989; 29:191 PNAS 1986; 83:767 ref:Vidard, Immunogenetics 1990; 32:27 PNAS 1986; 83:767 Science 1985; 229:566 Immunogenetics 1987; 26:304 Science 1987; 238:545 ref:Lai, PNAS 1987; 84:3845 J Immunol Methods 1990; 135:209 Cell 1984; 37:1101 Mol Cell Biol 1986; 6:4236 Nature 1985; 313:647 J Virol 1988; 62:839 Immunogenetics 1989; 29:191 Immunogenetice 1989; 29:191 Science 1985; 229:566 Immunogenetics 1987; 26:304 ref:Vidard, Immunogenetics 1990; 32:27 PNAS 1986; 83:767 refiBarth, Nature 1985; 316:517 re f:Bougueleret,Immunogenet 1987;26:304 refiBarth, Nature 1985; 316:517 Nature 1984; 312:40 Nature 1986; 324:679 Nature 1986; 321:219 Nature 1986; 324:679 Nature 1986; 324:679 Nature 1986; 324:679 Immunogenetics 1989; 29:191 PNAS 1986; 83:767 Science 1985; 229:566 ref:Vidard, Immunogenetics 1990; 32:27 PNAS 1986; 83:767 ref:Barth, Nature 1985; 316:517 Nature 1984; 309:322 Immunogenetics 1987; 26:304 Immunogenetica 1987; 26:304 Science 1987; 238:545 Science 1987; 238:545 Science 1987; 238:545 ref:Lai, PNAS 1987; 84:3845 ref:Barth, Nature 1985; 316:517 ref:Bouguel eret,I m munogenet 1987;26:304 Immunogenetic8 1989; 29:191 Science 1985; 229:566 Immunogenetics 1987; 26:304 ref:Vidard, Immunogenetics 1990; 32:27 PNAS 1986; 83:767 Continued on next p a g e

343

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Syrrdzda

Tcrb-V5

Locus Name

Tcrb-variable (VI35 family)

Terb-V5.1

Tcrb-VS.2 Tcrb-V5.3 Tcrb-V6

Tcrb-variable (V]36 family)

~

RFLVc Contac~

V135,F313 V~5 cos B39, A5, D13 TB21

+ +

pUCVa5 (=TB21) V]38, pUCV]38

+

pUCV~ + V~5.1 + cos 1339, B9, A5, B41, ~16 V~5.2 cos D13, r LB2 V~6

Tcrb-V7

Tcrb-variable (V~7 family)

+

V~6 cDNA VI36, V156.2 cos B29,1333, B16, ]347, B8 cos C1, C3, C42, C55, C10 VI37 " "

Tcrb-V8

Terb-variable (V~8 family)

VI37 cDNA Tcrb-V15.4 MDAI3 V~8 pUCVI38 TB3,TB2.1,TB12

Tcrb-V8.1

+ + +

125 Tcrb-V8.2

TB2

Tcrb-V8.3

V138.2 cos B39,Bg,A5,B41,D13,r TB23

Tcrb-V9

Tcrb-variable (V~9 family)

V]39, Vb9.2 V139

+

+

. Tcrb-V10

Tcrb-variable (V~]10 family)

cos D22, B29, B33 V~10 +

Tcrb-variable (VI311 family)

VI~10 cDNA cosmid D1A cos D5, D7, D10, C16 V]311

Tcrb-V12

Tcrb-variable (V~I2 family)

cos D22, B29, r TCR-F5 -BETA V~12

Tcrb-V13

Tcrb-variable (V1313 family)

cos D13, ~SE VI313

Tcrb -V 11

+ +

+ + + +

cos D13

Behlke eo:DY Loh Chou co:RK Barth co:Barth Klotz Barth Sim Klotz Behlke Chou co:M Davis Chou Patten co:RK Barth Behlke Bougueleret co:DY Loh co:M Davis Behlke Behlke Chou Chou co:DY Loh Behlke eo:DY Loh co:E Palmer Behlke Winoto Becket Behlke co: Loh co:DY Loh Klotz co:RK Barth co:Barth co:RK Barth Patten co:RK Barth co:Barth Behlke Chou co:RK Barth co:Barth Behlke Behlke co:DY Loh Bougueleret co:DY Loh co:P Singer Chou Behlke Behlke co:DY Loh co:DY Loh co:J Kobori Behlke co:E Lai Chou Behlke co:DY Lob co:P Singer Chou Palmer Behlke co:DY Loh co:P Singer Chou Behlke co:DY Loh co:DY Loh Chou

Refea~lcee

Science 1985; 229:566 ref:Vidard, lmmunogenetic8 1990; 32:27 Science 1987; 238:545 ref:Barth, Nature 1985; 316:517 ref:Bougueleret,Immunogenet 1987;26:304 Immunogenetics 1989; 29:191 Nature 1985; 316:517 Cell 1985; 42:89 Immunogenetics 1989; 29:1ql PNAS 1986; 83:767 Science 1987; 238:545 refiLai, PNAS 1987; 84:3846 Science 1987; 238:545 Nature 1984; 312:40 ref:Barth, Nature 1985; 316:517 PNAS 1986; 83:767 Immunogenetics 1987; 26:304 ref:Vidard, Immunogenetics 1990; 32:27 ref:Lai, PNAS 1987; 84:3846 PNAS 1986; 83:767 Science 1985; 229:566 Science 1987; 238:545 Science 1987; 238:545 ref:Haqqi, J Exp Med 1989; 189:1903 Science 1985; 229:566 ref:Vidard, Immunogenetics 1990; 32:27 ref:Lai, PNAS 1987; 84:3845 PNAS 1986; 83:767 Nature 1986; 324:679 Nature 1985; 317:430 Science 1985; 229:566 ref: Nobuhara, Immunogenetics 1989; 30:405 ref:Vidard, Immunogenetics 1990; 32:27 Immunogenetics 1989; 29:191 ref:Barth, Nature 1985; 316:517 re f:Bougueleret,Immunogenet 1987;26:304 ref:Barth, Nature 1985; 316:517 Nature 1984; 312:40 ref:Barth, Nature 1985; 316:517 re f:Bougueleret,Immunogenet 1987;26:304 PNAS 1986; 83:767 Science 1987; 238:545 ref:Barth, Nature 1985; 316:517 re f:Bougueleret,I mmunogeneC 1987;26:304 Science 1985; 229:566 PNAS 1986; 83:767 refiHaqqi, J Exp Med 1989; 169:1903 Immunogenetics 1987; 26:304 ref:Vidard, Immunogenetics 1990; 32:27 ref:Lai, PNAS 1987; 84:3846 Science 1987; 238:545 Science 1985; 229:566 PNAS 1986; 83:767 ref:Haqqi, J Exp Med 1989; 169:1903 ref:Vidard, Immunogenetics 1990; 32:27 ref:Lai, PNAS 1987; 84:3840 PNAS 1986; 83:767 ref:Lai, PNAS 1987; 84:3846 Science 1987; 238:545 PNAS 1986; 83:767 ref:Vidard, Immunogenetics 1990; 32:27 ref:Lai, PNAS 1987; 84:3846 Science 1987; 238:545 Nucl Acid Res 1989; 17:2353 PNAS 1986; 83:767 reflVidard, Immunogenetics 1990; 32:27 refiLai, PNAS 1987; 84:3846 Science 1987; 238:545 PNAS 1986; 83:767 ref:Haqqi, J Exp Med 1989; 169:1903 refiVidard, Immunogenetics 1990; 32:27 Science 1987; 238:545 C o n t i n u e d on next p a g e

344

J.T. Eppig: Clones and Probes

Table 3. Continued. Chr Symbola

6

6

6

6

6 6 6 6 6

6 6 6 6

7 7

7 7

7 7 7 7 7 7

7

7 7

Tcrb-V14

Locus Name

Tcrb-variable (V[514 family)

Probeb

pUCV]M4 46.1J6.19, 2.3w7, 1.1J6.19, 40.1w7, V~14GL, V~14J6.19 V]M4J6.19 SJI23 SJL73 cos B16, B47, B8 V~15

RFLVc Comactd

+

Klotz Malissen Malissen Malissen co:DY Loh Behlke Tcrb-V15 Tcrb-variable (V~15 family) Behlke Chou co:DY Loh co:M Davis Tcrb-V16 Tcrb-variable (V~16 family) Tcrb-B10, Tcrb-4.C3 Winoto " Fink V!516 co:DY Loh co:E Palmer cos D5, D7, D10 Chou cesmid D1A co:E Lai SJIA Behlke Tcrb-V17 Tcrb-variable (V~17 family) vB17 Kappler Bougueleret V~17a co:P Marrack + co:J Kappler Tcrb-V18 Tcrb-variable (Vbl8 family) cesC1,C3,C42,C55,C 10,E21 Chou Tcrb-V20 Tcrb-variable (Vb20 family) cosmida D18, D6, co:PN Marche PCR KOUP, MTBSX primers co:PN Marche Tnfr-2 tumor necrosis factor receptor-2 mTNT-R2 eDNA Lewis TNFR-2 eDNA + Goodwin Tnfr-2 (SL/Am) eDNA co:W Lesslauer Tpi- 1 triosephosphate isomerase-1 TPI eDNA co:LE Maquat [H] pHTPI-5A Maquat + co:LE Maquat Try- 1 trypsin-1 [R] clone 4-79 Craik + co:W Rutter [R] pcXP4-78 Honey pMPt9 Stevenson trypsin T a kMT4 Stevenson Vin-1 viral integration site, radiation leukemia 4A-l, 4A-5, 4A-11, 4A-21, co:P Jolicoeur 4A-29, PRO.6, PRO.7 co:P Jolicoeur Wnt-2 wingless-related MMTV integration site-2 clone2, clone 4, clone 7 + McMahon clones I1,I2,I3,I4,I5,I6,I7, 8,I9 Chan Wnt-2 eDNA Gavin Wnt-5B wingless-related MMTV integration site-5b Wnt-5b eDNA Gavin Wnt-7A wingless-related MMTV integration site-7a Wnt-7a eDNA Gavin Xmmv-27 xenotropic-MCF leukemia virus-27 pMo-MCFI-16 + co:M Vogt Xrnv-24 xenotropic murine leukemia virus-24 JS-6flS-10 Frankel + Frankel JS-6+JS-10, XENOll2 + Frankel Akv-1 (withdrawn, = E m v - l l ) Apoe apolipoprotein E p2Cl + Lusis Rajavashisth + co:AJ Lusis + co:AJ Lusis Apoe genemic Horiuchi Apoe eDNA Horiuchi Ass-psl arginosuccinate synthetase, pseudogene-1 [H] pAS-1 co:Beaudet Atpla3 ATPase, Na+K +, a3 polpeptide [R] rb-2 + Kent + Cavanna [R] pAl + co:R Levenson + co:R Levenson BI(D7Rp2) B1 repeat within D7Rp2 pMAK-1, X-M58 Snider pMAK- 1, pBR650 King Bcl-3 B-cell leukemiaflymphoma-3 mobcl3.1, mobcl3.4 + Bhatia Bgp biliary glycoprotein clone bb-1 Robbins c albino (see Tyr: tyrosinase below) C58v-4 (withdrawn, =Emv-23) Calc calcitonin [R] CT-89 Jacob~ Lalley + co:JW Jacobs + co:JW Jacobs Calm calmondulin clone 21 Baughman Cd43 CD43 antigen (leukosialin, Ly-48) GL1 la Cyster ML18 co:J Frelinger Ly-48 cosmid Dorfman Cea carcinoembryonic antigen [I-I] pCEA1 Zimmermann + co:ATCC mCEA1 Beauchemin

Referencee

Immunogenetics 1989; 29:191 Nature 1986; 319:28 Nature 1986; 319:28 Nature 1986; 319:28 ref:Vidard, Immunogenetics 1990; 32:27 PNAS 1986; 83:767 PNAS 1986; 83:767 Science 1987; 238:545 ref:Vidard, Immunogenetics 1990; 32:27 ref:Lai, PNAS 1987; 84:3846 Nature 1986; 324.'679 Nature 1986; 321:219 ref:Vidard, Immunogenetics 1990; 32:27 ref:Lai, PNAS 1987; 84:3846 Science 1987; 238:545 ref:Lai, PNAS 1987; 84:3846 PNAS 1986; 83:767 Cell 1987; 49:263 Immunogenetics 1987; 26:304 ref:Haqqi, J Exp Med 1989; 169:1903 ref:Vidard, Immunogenetics 1990; 32:27 Science 1987; 238:545 refiSix, J Exp Meal 1991; 174:1263 ref:Six, J Exp Meal 1991; 174:1263 PNAS 1991; 88:2830 Mol Cell Biol 1991; 11:3020 ref:Rothe, Immunogenet 1991; 34:338 ref:Cheng, Nucl Acid Res 1990; 18:4261 J Biol Cbem 1985; 260:3748 ref:Siracusa, Genetics 1991; 127:169 J Biol Chem 1984; 259:14255 ref:Bucan, EMBO J 1986; 5:2899 Som Cell Mol Genet 1984; 10:377 Nucl Acid Rea 1986; 14:8307 Nucl Acid Re~ 1986; 14:8307 ref:Tremblay, J Virol 1992; 66:1344 ref:Tremblay, J Virol 1992; 66:1344 Development 1989; 107:643 Somatic Cell Mol Genet 1989; 15:555 Genes & Development 1990; 4:2319 Genes & Development 1990; 4:2319 Genes & Development 1990; 4:2319 ref: Blatt, PNAS 1983; 80:6298 J Virol 1989; 63:1763 Genetics 1990; 124:221 M a m m Genome 1992; 2:110 J Biol Chem 1987; 262:7594 PNAS 1985; 82:8085 ref:Saunders, Genomics 1990; 6:324 ref:Saunders, Genomics 1990; 8:525 J Biochem 1989; 106:98 J Bioehem 1989; 106:98 ref:Nakamura, Cytogen Cell Cen 1985; 40:710 PNAS 1987; 84:5369 Genomics 1990; 7:12 ref:Saundera, Genomics 1990; 6:324 ref:Saunders, Genomics 1990; 8:525 J Biol Chem 1985; 260:9884 Mol Cell Biol 1986; 6:209 Oncogene 1991; 6:1569 Genomics 1991; 10:583 Science 1981; 213:457 Cytogenet Cell Genet 1987; 44:92 ref:Saunderu, Genomics 1990; 6:324 ref:Saunders, Genomics 1990; 8:525 Mol Endoerinol 1991; 5:637 Eur J Immtmol 1990; 20:875 ref:Baecher, Immunogenetics 1990; 31:307 Nucl Acid Res 1990; 18:4932 PNAS 1987; 84:2960 ref:Siracusa, Genomics 1991; 10:313 Cane Res 1991; 49:2017 Continued on next p a g e

J.T. Eppig: Clones and Probes

345

Table 3. Continued. C~w Symbola

7

Cea-1

7 7

Cea-2 Cebp

7

Ckmm

7

Cyp2a

7

Cyp2a4

7

Cyp2a5

7

Cyp2b

Locus Name

Cyp2b9

Cyp2bl0

Cyp2el

Cyp2f D19FllSlh D19S19h D19SSlh

D7Ag2 "D7Cw2P" "D7Cw2D" "D7CwllP" "D7CwllD" "D7Cwl8" "D7H8" D7Hdl.7 D7Hd3U "D7McCI" "D7McC2" D7Nicl D7Orl D7Rn 1 D7Rn2 D7Rp2

Probeb

RFLVc C o a t ~

carcinoembryonic antigen gene family-1 CGM1 Turbide MHVR10.4~IHVR10.3,pl0.3 co:KV Holmes MHVR1, p10.4, pMHVR1 co:KV Holmes carcinoembryonic antigen gene family-2 mmCGM2, mmCGM4 Turbide CCAAT/enhancer binding protein [R] C/EBP eDNA Landschulz " + Birkenmeier CepbI, CeFbII + Xanthopoulos CephI + eo:K Xanthopoulos creatine kinase, muscle [H] Ckmm genomic + co:Wieringa I-H]pJN2CK-M + Saunders + Saunders MCK Bushkin " co:J Bushkin MUSMCKA (microsat) + co:JA Todd (micmsat) + co:JA Todd eytochrome P450, 2a, phenobarbitol inducible [HI pMP81 + Miles + Matsunaga [R] Cyp2al cDNA [H] P450-IIA3 Yamano + co:F Gonzalez cytochrome P450, 2a4, phenobarbitol p15a-29 Burkhart inducible (=15aoh-1) probe r + Burkhart C1, J202, J2, JS, J23 Burkhart cytochrome P450, 2a5, phenobarbitol plSce29 Burkhart inducible (=15aoh-2, =Coh) probe r + Burkhart C'2, J29, J21 Burkhart cytochrome P450, 2b, phenobarbitol inducible [R] pP450b-5 Gonzalez Simmons + co:CB Kasper + co:CB Kasper + Simmons [H] pSP450 + co:M Adesnik cytochrome P450, 2b9, phenobarbitel [R]R17 (P450-e) co:M Adesnik inducible (=16aoh) Noshiro pt26 Noshiro " Noshiro k242, ;~6, ~.117, ~.15, M01 Lakso Z225, ~.705 Lakso eytochrome P450, 2b10, phenobarbitol [R]R17 (P450-e) co:M Adesnik inducible (=16~oh) p{3, pf46, pf40, pfll Noshiro Noshiro ~02, ~ Lakso eytochrome P450, 2el, ethanol inducible [H] P450IIE eDNA Miles [R] Cyp2el eDNA Song + Gonzalez pAR-1 Voliva Cyp2el cDNA,Cyp2el genomic eo:R Wolf cytoehrome P450, 2fl [H] IIF1 Nhamburo Nah-2 co:ID Owens DNA segment, Chr 7, h u m a n D19FIlS1 [H] OL5 Jandel + Saunders DNA segment, Chr 7, human D19S19 [H] p17.4-4(2) + co:J Gilbert DNA segment, Chr 7, human D19S51 [H] p134A + Cavanna DNA segment, Chr 7, Agouron Inst.-2 (brain) [R]lB236 + Blatt DNA segment, Chr 7, Case Western-2P kl4RIc2 Sharan DNA segment, Chr 7, Case Western-2D kl4RIc2 Sharan DNA segment, Chr 7, Case Western-liP pv0,4AP Sharan DNA segment, Chr 7, Case Western-liD pA4.scl 1 Sharan DNA segment, Chr 7, Case Western-18 palbl8 + co:T Magnuson DNA segment, Chr 7, H8 eesmid H8 Boyle DNA segment, Chr 7, Heidelberg-l.7 I~JLE1.7 eo:T Magnuson DNA segment, Chr 7, Heidelberg-3U pE3U.HS + Niswander DNA segment, Chr 7, McClelland-1 AP-PCR oligo KB + co:M McClelland DNA segment, Chr 7, McClelland-2 AP-PCR oligo KB + eo:M McClelland DNA segment, Chr 7, Nicholls-1 [J-I] DN10 + Nicholls DNA segment, Chr 7, Oak Ridge-1 llB2 + Johnson DNA segment, Chr 7, Rinchik-I RN207, RN207.2 co:EM Rinchik DNA segment, Chr 7, Rinchik-2 RN226, RN226.1 co:EM Rinchik DNA segment, Chr 7, Roswell Park-2 pMKg08 Berger + co:FG Berger + co:G Watson + Elliott Tseng-Crank pMAK- 1, ~.-M58 Snider pMAK-1 King pMAK-1E + King pMAK-5H, pMAK-4 King

Refe~e~~

J Biol L~em 1991; 286:309 ref:Dveksler, J Virol 1991; ~h5:6881 ref:Dveksler, J Virol 1991; 65:6881 J Biol Chem 1991; 266:309 Genes Dev 1988; 2:786 Genes Dev 198~ 3:1146 Cytogenet Cell Genet 1989;, 50:174 ref:Saunders, Genomics 1990; 8:525 ref: Cavanna, Genomics 1990; 7:12 Genomics 1990; 6:324 Genomics 1990; 8:525 J Mol Evo11985; 22:334 ref:Lyons, Development 1991; 113:1017 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 Genomics 1990; 7:445 Biochemistry 1990; 29:1329 Nucl Acid Res 1989; 17:4888 ref:Saunders, Genomics 1990; 8:525 J Biol Chem 1985; 260:15357 Gene 1990; 87:205 Gene 1990; 87:205 d Biol Chem 1985; 260:15357 Gene 1990; 87:205 Gene 1990; 87:205 J Biol Chem 1982; 257:5962 J Biol Chem 1985; 260:515 ref:Saunders, Genomics 1990; 6:324 ref:Saunders, Genomics 199{3,;8:525 J Biol Chem 1983; 258:9585 tel:Miles, Genomics 1990; 7:445 ref:Ncshiro, Arch Bioch Biophs 1986; 244:857 Biochemistry 1988; 27:6434 Biochemistry 1988; 27:6434 Biochemistry 1988; 27:6444 E u r J Biochem 1991; 195:477 Eur J Biochem 1991; 195:477 ref:Noshiro, Arch Bioch Biophs 1986; 244:857 Biochemistry 1988; 27:6434 Biochemistry 1988; 27:6444 E u r J Biochem 1991; 195:477 Genomics 1990; 7:445 J Biol Chem 1986; 261:16689 DNA & Cell Biol 1990; 9:771 J Mol Endocrinol 1991; 7:155 ref:Freeman, Biochem J 1992; 281:689 Biochemistry 1990; 29:5491 ref:Ritter, Biochemistry 1991; 30:11430 Cytogenet Cell Genet 1985; 40:660 Genomics 1990; 8:525 ref:Saunders, Genomics 1990; 6:324 Genomics 1990; 7:12 Cytogenet Cell Oenet 1985; 40:583 Genetics 1991; 129:825 Genetics 1991; 129:825 Genetics 1991; 129:825 Genetics 1991; 129:825 ref:Niswander, Genomics 1991; 9:162 Genomics 1992; 12:106 ref:Niswander, Oenomics 1991; 9:162 Genomics 1991; 9:162 tel:Welsh, Nucl Acid Res 1991; 19:5275 tel:Welsh, Nucl Acid Res 1991; 19:5275 Mouse Ne~s Lett 1989; 84:87 PNAS 1989; 86:8862 ref:Klebig, PNAS 1992; 89:1363 ref:Klebig, PNAS 1992; 89:1363 J Biol Chem 1981; 256:7006 ref:Saunders, Genomics 1990; 6:324 ref:Saunders, Genomics 1990; 8:525 PNAS 1983; 80:501 Genetics 1987; 116:593 J Biol Chem 1985; 260:9884 Mol Cell Biol 1986; 6:209 Mol Cell Biol 1986; 6:209 Mol Cell Biol 1986; 6:209 C o n t i n u e d on next p a g e

346 Table 3.

J.T. Eppig: Clones and Probes

Continued.

Chr Syrntxia

Locus Name

Prd~

RFLVc C(mtactd

7 7 7 7 7 7 7 7 7 7 7

"D7RT305" DNA segment, Chr 7, RalfTonjes 305 1~305 "D7RT336B" DNA segment, Chr 7, RalfTonjes 336B E336B "D7RT453B" DNA segment, Chr 7, RalfTonjes 453B E453B D7Smh53 DNA segment, Chr 7,St.Mary's Hospital-53 D7Smh53 D7Smh57 DNA segrnent, Chr 7,St.Mary's Hospital-57 D7Smh57A D7Smh59 DNA segment, Chr 7,St.Mary's Hospital-59 D7Srah59 D7Smh71 DNA segrnent, Chr 7,St.Mary's Hospital-71D7Smh71 D7Smh75 DNA segment, Chr 7,St.Mary's Hospital-75 D7Smh75 " D 7 T m 3 a " DNA repeat, Chr 7, within cl l D S D deletion pTME3a, pTME3al.47 D7TmI8 (withdrawn, =D7CwlS) D7Wasl2 DNA segment, Chr 7, Univ. Wash.-12 clone 12A

7 7 7

Egtbp Egibp-1 Egtbp-2

epidermal growth factor binding protein EGF binding protein (type A) EGF binding protein (type B, mGK-13)

7

Egfbp-3

EGF binding protein (type C, mGK-9)

7

Emv-ll

endogenous ecotropicMuLV-11

7

Emv-23

endogenous ecotropic MuLV-23

Ercc-2 "Fah" Fes

excision repair-2 fumarylacetoacetate hydrolase feline sarcoma oncogene

pEco, pEc-B4

+

Taylor

IV] pEnv ecotropic virus probe pEco pEc-B4

+ +

co:NA J e n k i n s Silver Chattopadhyay Chan co:Chan Taylor Rinchik Rinchik Rinchik co:E Rinchik co:D Lowy Saunders co:EM Rinchik Franchini co:C Blatt Wilks Wilks co:P D'Eustachio co:C Sherr co: C Sherr co:C Sherr co: C Sherr Shibuya Bremner co:H H a n a f u s a

env-probe [H] pKER2 RN273 [H] kN26 [H] pN26 (from kN26) pC.I, ).18.1, k133.2, XC.1, pF18.1, )*B.1 Fes probe [V] v-Fes [V] v-fesPstI-3

+ +

+ + + + + + + +

[V] v-fesPstI-4 pBRFO4 + IV] v-fpsBamHI-4 [H] pS0 + 7

Fis-1

Friend virus integration site-i

[H] Fes e D N A dFis-1 genomic pl.8

+ +

7 7

"Fosb" Fur

FBJ osteosarcoma oncogene B furin, membrane assocated receptor prot

7 7 7

Gabrb-3 "Garp" Gas-2

GABA-A receptor, subunit 13-3 unknown n a m e growth arrest specific gene-2

7

Gpi-1

glucose phosphate isomerase-1

Tonjes Tonjes Tonjes co:SDM Brown co:SDM Brown co:SDM Brown co:SDM Brown co:SDM Brown co:T Magnuson

Disteche + co:C Disteche + co:C Disteche MB2-12A + co:M Blabor kMSP-47,%MSP-63,kM SP-57 Evans Egtbp-2 eDNA Evans Drinkwater ~MSP-56,)*MSP-48,XMSP-45 Evans kMSP-65,)*M SP-20,%MSP-24 Evans pPRECE-2 co:K N a k a y a m a pSGP-2 Lundgren Egfbp-3 eDNA Evans Drinkwater MB1-73, MB2-20A Blaber cMSP-l,cMSP-22,cMSP-9 E v a n s kMSP-32,XMSP-36,LMSP-39, Evans Z2dSP-40,)*MSP-66 Evans [V-] pEnv + co:NA J e n k i n s pEco Chattopadhyay pEc-B4 Chan

pEco, pEe-B4 pEmv-23.1,pEmv-23.2 pEmv-23, pEmv-23.4 pEmv-23.3 7 7 7

+ + + + + + + +

pO.8, Fis-1 genomic ccsmid B2, clone ACll3-1 clone 5B " [H] JP5 + BL Gas-2 eDNA- 1 Gas-2 eDNA-2 + "

pgiT.t [Y] Gpi-1 genomic [H] HS-10 Gpi-1 probe

Sadroski Saunders co:B Kacinski co:J Silver co:J Silver co:J Silver co:J Silver

Silver co:R Bravo Seidah Seidah co:M Lalande co:D Birnbaum Schneider Colombo

+

co:P D'Eustachio

+ +

Faik co: A. Aguilera co:T Siddique co:P Faik

Ref~e~ee

Genomics 1991; 10:686 Genomics 1991; 10:686 Genomics 1991; 10:686 ref: Greenfield, Genomics ref: Greenfield, Genomics personal communication ref: Greenfield, Genomics personal communication ref:Niswander, Genormcs

1987; 1:153 1987; 1:153 1987; 1:153 1991; 9:162

Somatic Cell Mol Genet 1984; 10:211 ref:Saunders, Genomics 1990; 8:525 ref:Niswander, Genomics 1991; 9:162 ref:Saunders, Genomics 1990; 8:525 J Biol Chem 1987; 262:8027 J Biol Chem 1987; 262:8027 Biochemistry 1987; 26:6750 J Biol Chem 1987; 262:8027 J Biol Chem 1987; 262:8027 ref:Kim, FEBS Lett 293:142 J Biol Chem 1984; 259:7780 J Biol Chem 1987; 262:8027 Biochemistry 1987; 26:6750 Biochemistry 1987; 26:6742 J Biol Chem 1987; 262:8027 J Biol Chem 1987; 262:8027 J Biol Chem 1987; 262:8027 J Viral 1982; 43:26 PNAS 1980; 77:5774 PNAS 1980; 77:5579 Genomics 1989; 5:221 J Viral 1982; 43:28 J Viral 1985; 55:494 PNAS 1980; 77:5774 PNAS 1980; 77:5579 ref: Silver, J Viral 1985; 55:494 Genomics 1989; 5:221 Genomics 1989; 4:251 Genomics 1989; 4:251 Genomics 1989; 4:251 ref:Saunders, Genomics 1990; 8:525 ref:Rinchik, Genomics 1989; 4:251 Genomics 1990; 6:324 ref:Klebig, PNAS 1992; 89:1363 Mol Cell Biol 1982; 2:1014 Mol Cell Biol 1984; 4:978 Oncogene 1988; 3:289 Oncogene 1988; 3:289 ref:Colombo, M a m m Genome 1992; 2:130 ref:Matsunaga, Biochemistry 1990; 29:1329 ref: Kozak, J Viral 1983; 47:217 ref: Stall, Genomics 1990; 7:88 ref: Kozak, J Viral 1983; 47:217 J Viral 1982; 42:1007 Cell 1990; 61:407 ref: Kozak, J Viral 1983; 47:217 PNAS 1984; 81:3039 Genomics 1990; 6:324 ref:Sundaresan, Sam Cell Mol Gen 1989;15 J Viral 1986; 60:1156 J Viral 1986; 60:1156 J Viral 1986; 57:526 ref:Saunders, Genomics 1990; 8:525 J Viral 1986; 57:526 ref:Lazo, Nucl Acid Res 1992; 20:343 Mol Endocrinol 1991; 5:111 Genomics 1991; 11:103 ref:Wagstaff, Genomies 1991; 11:1071 ref:Ollendorff, M a m m Genome 1992; 2:195 Cell 1988; 54:787 Nucl Acid Res 1989; 17:7545 ref:Colombo, M a m m Genome 1992; 2:130 Nature 1988; 332:455 refi Faik, Nature 1988; 332:455 ref:Saunders, Genomics 1990; 8:525 ref:Siracusa, Genetics 1991; 127:169 C o n t i n u e d on n e x t I

J.T. Eppig: Clones and Probes

347

Table 3. Continued. Cbr Syrnl~a

LoonsName

7

H19

H19, fetal liver mRNA

7

Hbb

hemoglobin 13 chain complex

Pr~

RFLVc Contactd

pill9, ~.H19.5 + kill 9.5,%H 19.6,~.H19.10 7~H19.12, kill9.13 2xH19, H19RS H19RS + H19 genomic + MyoH cDNA LC10-8, LCI0-8/1, LC-IO/1 p~G1 kgtWES.M]3G3 pMBd2, pMBJ [H] pBR:]3 pPK268

+ + +

pTK1HI-1

hemoglobin ]3 chain (M. caroli) 7

+ MMBGLOFG (microsat)+ MMBGCXD (microsat) + )83-4, k83-2, )83-12, k83-10 )83-25, )83-5, k83-8, k83-30, ~83-11, )83-22, ~t~3-13 pCR1]3MG3 plaque5156 + plaqueA42 pMBd2, pMBJ kgtWES.M]3G1 LgtWES.MI3G2

Hbb-bl

hemoglobin ]3 chain (]3 major)

Hbb-bl s

" hemoglobin ]3 major chain (single allele) p~11R3 BA2,BA4 BA2

+

co:Pachnis Pachnis Pachnis Pachnis co:S Tilghman Bartolomei Davis Poirier co:D Housman Tiemier co:Leder Lo Patent 4,683,194 Skow co:R Popp co:R Popp Gilmour Sremner co:JA Todd co:JA Todd Casavant Casavant Casavant Rougeon Goldberg Goldberg co:P Leder Tilghman Tiemier Tilghman co:P Leder Todokoro Weaver Edgell

Hbb-bl d

hemoglobin ]3 major chain (diffuse allele) CA4, CAll

Edgell

Hbb-b2 d

hemoglobin 13 minor chain (diffuse allele) CA4 CE8, CE14

Jahn Edgell

Hbb-b2s

hemoglobin [3 minor chain (single allele) BA1,BA3 BA3 BA1, BA3 pCR1]3M9

+ Weaver Shyman Edgell +

Edgell

+ + "Hbb-th 1"

deletion associated with I-Fobinsert

Hbb-y

hemoglobin Y (]3-like embryonic)

Hbby s

pilE100, BA12 fragment E hemoglobin Y (]3-like embryonic, s allele) BA12

Hbb .yd

hemoglobin Y (~-like embryonic, d allele) CE12, CE18, CE19

Hbb-yc Hbb-bh0

plaque5156 plaqueA42 pYSIFJB BAll

co:Edgell,Rougeon Bishop Goldberg + Goldberg Todokore Weaver Holdener-Kenny Holdener-Kenny + Holdener-Kenny Edgell Edgell

CE12, CE18, CE19 hemoglobin Y (]3-like embryonic, M caroli) k83-8, ).83-11, :k83-13, )83-22, )83-30, k83-2, )83-4, )83-12 hemoglobin ~ homologous gene 0 BAll

Jahn co:Edgell co:Edgell co:Edgell Weaver Holdener-Kenny BA12, CE12, CE18, CE17, CAll Edgell

(Mus caroli) (Mus caroli)

CE12, CE18, CE19, CE17 fragment B + fragment H, fragment P pilE100, C505, BA12 )83-11, Zk~3-13,)83-22, )83-2, )83-12

Jahn Holdener-Kenny Holdener-Kenny Holdener-Kenny co:Edgell co:Edgell

Referencee

PNAS 1984; 81:5523 EMBO J 1988; 7:673 EMBO J 1988; 7:673 EMBO J 1988; 7:673 ref:Saunders, Genomics 1990; 8:525 Nature 1991; 351:153 Cell 1987; 51.O87 Development 1991; 113:1105 ref:Berger, J Biol Chem 1981; 256:7006 Cell 1978; 14:237 refi Tilghman, PNAS 1977; 74:4406 Differentiation 1987; 35:37 ref:Saunders, Genomic8 1990; 8:525 Cell 1983; 34:1043 ref:Rinchik, Genomics 1989; 4:251 ref:Johnson, PNAS 1989; 86:8862 EMBO J 1984; 3:1263 Cell 1990; 61:407 ref:Aitman, Mamm Genome 1991; 1:206 ref:Hearne, Mamm Genome 1991; 1:273 Mol Cell Biol 1988; 8:4669 Mol Cell Biol 1988; 8:4669 Mol Cell Biol 1988; 8:4669 Gene 1977; 1:229 J Biol Chem 1986; 261:12368 J Biol Chem 1986; 261:12368 ref:Lo, Differentiation, 1987; 35:37 PNAS 1977; 74:4406 Cell 1978; 14:237 PNAS 1977; 74:4406 refiHonjo, Cell 1979; 18:559 BBRC 1986; 135:1112 Cell 1981; 24:403 In: Organization and Expression of Globin Genes, 1981; pp69-88 In: Organization and Expression of Globin Genes, 1981; pp69-88 Cell 1980; 21:159 In: Organization and Expression of Globin Genes, 1981; pp69-88 Cell 1981; 24:403 Nucl Acid Res 1985; 13:5085 In: Organization and Expression of Globin Genes, 1981; pp69-68 In: Organization and Expression of Globin Genes, 1981; pp69-68 ref: Rougeon, Gene 1977; 1:229 PNAS 1986; 83:5568 J Biol Chem 1986; 261:12368 J Biol Chem 1986; 261:12368 BBRC 1986; 135:1112 Cell 1981; 24:403 PNAS 1986; 83:4374 PNAS 1986; 83:4374 PNAS 1986; 83:4374 In: Organization and Expression of Globin Genes, 1981; pp69-88 In: Organization and Expression of Globin Genes, 1981; pp69-88 Cell 1980; 21:159 ref:Casavant, Mol Cell Biol 198;8; 8:4669 ref:Casavant, Mol Cell Biol 198:8; 8:4669 ref:Casavant, Mol Cell Biol 1988; 8:4669 Cell 1981; 24:403 PNAS 1986; 83:4374 In: Organization and Expression of Globin Genes, 1981; pp69-88 Cell 1980; 21:159 PNAS 1986; 83:4374 PNAS 1986; 83:4374 PNAS 1986; 83:4374 refiCasavant, Mol Cell Biol 1988; 8:4669 ref.'Casavant, Mol Cell Biol 1988; 8:4669 Continued on next page

348

J.T. Eppig: Clones and Probes

Table 3. Continued. Chr Symbola

7

Hbb -bhl

L a ~ Name

hemoglobin 15homologous gene 1

Pr~eb

RFLVc Cxta~actd

BAll BA12, BAIl + CE12, CE19, CE17 CE12, CE17, CE19

(Mus caroli)

7

Hbb-bh2

hemoglobin ~ homologous gene 2

( M u s caroli)

7

Hbb-bh3

hemoglobin ~ pseudo-bh3

BA12, pilE100 )~83-5,M~3-13~83-25,k83-10 BA12 + BAll, CE12, CE17, CE19 GEl2, CE19, CE17 ).83-5, ).83-25, k83-10 bh3 BA12

+ +

BAll, CE17 7

Hras-1

Harvey r a t sarcoma virus oncogene

CE17 clone BS9

[H] HB-11 "

+ +

7 7

Hrc Hstf- 1

7

Igflr

[H] c-Ha-ras-1 [H] pC-ras-1 IV] v-Ha-ras Hras probe histidine-rich calcium binding protein [HI ~.hHRC heparin secretory transforming protein-1 clones 13, 9, 6, 17, 14, 4 (homolog of oncogene hst/k-FGF) COS16, ~.1 COS16 [H] b.st probe c %1, COS16 L361-M3, M1.8 M1.8 insulin-like growth factor I receptor [H] Igfr85 [H] pIGF-I-R.8

7

Igf-2

insulin-like growth factor-2

7

I14r

interleukin 4 receptor

7

Ins-2

insulin II

7

Int-2

(from NON mice) m a m m a r y tumor integration site-2

+

+ +

[H] Igflr PCR-Igflr migl2-1, migf2-3 IGF-II3.1 [H] Igf PCR-Igf Z.IGF6, cosIGF4, cos IGF5 [R] Igf-2 eDNA + e119 clone B-4 mulL-4rPR (from B-4) + pcDNA I/IL-4R + kin2 klGF6 pMI-II ).Nins-II clones 208,401, 408 probes 218, 232, 411, 418 ).218, k418, ).3, ).4 pU418 (Int-2 genomic) + " 418 A + Z.3,C1, C2, C3 probes a,h,c,d,e,f,g,h,ij probes a, b, c, d, e, f, g,h Int-2a (=probe a) + int-2c, int-2f(from pU418) int-2f, int-2g (=probe f, g) + probe f (=int-2f)

aef~

Cell 1981; 24:403 PNAS 1986; 83:4374 Cell 1981; 24:403 PNAS 1986; 83:4374 Cell 1980; 21:159 In: Organization and Expression of Globin Genes, 1981; pp69-88 Holdener-Kenny PNAS 1986; 83:4374 co:Edgell ref:Casavant, Mol Cell Biol 1988; 8:4669 Weaver Cell 1981; 24:403 Holdener-Kenny PNAS 1986; 83:4374 Edgell In: Organization and Expression of Globin Genes, 1981; pp69-88 Jahn Cell 1980; 21:159 co:Edgell ref:Casavant, Mol Cell Biol 1988; 8:4669 Bellis Mol Biol Evol 1987; 44:351 Weaver Cell 1981; 24:403 Holdener-Kenny PNAS 1986; 83:4374 Edgell In: Organization and Expression of Globin Genes, 1981; pp69-88 Jahn Cell 1980; 21:159 Ellis J Virol 1980; 36:408 Sakaguchi PNAS 1984; 81:525 Pravteheva Somatic Cell Genet 1983; 9:681 Bremner Cell 1990; 61:407 Ellis Nature 1981; 292:506 Saunders Genomics 1990; 6:324 Saunders Genomics 1990; 8:525 co:RW Ellis ref:Colombo, M a m m Genome 1992; 2:130 co:D Lowy, E Chang ref: Kozak, J Virol 1983; 47:217 co:D Lowy, E Chang ref: Kozak, J Virol 1983; 47:217 Kozak J Virol 1983; 47:217 Bhatia Oncogene 1991; 6:1569 Hofmann Genomics 1991; 9:656 Brookes Nucl Acid Res 1989; 17:4037 Brookes Nucl Acid Res 1989; 17:4037 co:G Peters ref:Tiesman, Gene 1990; 96:311 co:Terada ref.'Peters, PNAS 1989; 86:5678 Peters PNAS 1989; 86:5678 Yoshida BBRC 1988; 157:618 Suzuki Devel Biol 1992; 150:219 co:A Ullrich ref:Sundaresan, Som Cell Mol Gen 1989;15:373 Saunders Genomica 1990; 6:324 co:A Ullrich ref:Colombo, M a m m Genome 1992; 2:130 Ullrich EMBO J 1986; 5:2503 Telford Mol Reprod Devel 1990:27:81 Stempien DNA 1986; 5:357 DeChiara Nature 1990; 345:78 Dull Nature 1984; 310:777 Telford Mol Reprod Devel 1990:27:81 Rotwein DNA Cell Biol 1990; 9:725 Soares J Mol Biol 1986; 192:737 co: A Efstratiadis ref:Bartolomei, Nature 1991; 351:153 Harada PNAS 1990; 87:857 Moseley Cell 1989; 59:335 Pritchard Genomics 1991; 10:801 co:J-I Ohara ref:Susuki, Immunogenetics 1991; 34:252 Wentworth J Mol Evol 1986; 23:305 co: JM Chirgwin ref:Rotwein, DNA Cell Biol 1990; 9:725 Rotwein DNA Cell Biol 1990; 9:725 Wentworth J Mol Evol 1986; 23:305 Sawa J Mol Endocrinol 1990; 5:61 Dickson Cell 1984; 37:529 Dickson Cell 1984; 37:529 Dickson Cell 1984; 37:529 Bremner Cell 1990; 61:407 Casey Mol Cell Biol 1986; 6:502 co:Silver, Buckler ref:Moen, M a m m Genome 1991; 1:217 Moore EMBO J 1986; 5:919 Dickson Cell 1984; 37:529 Moore EMBO J 1986; 5:919 co:G Peters ref:Silver, J Virol 1986; 80:1156 Casey Mol Cell Biol 1986; 6:502 Wilkinson EMBO J 1988; 7:691 co:A McMAhon ref:Bartolomei, Nature 1991; 351:153 co:G Peters, C DicksonrefiJakobovits, PNAS 1986; 83:7806 Weaver Holdener-Kenny Weaver Holdener-Kenny Jahn Edgell

Continued on next page

J.T. Eppig: Clones and Probes

349

Table 3. Continued. C"nr Symbola

7

7 7

Int-2

~

Name

Probe b

RFLVc C(mlac~d

Referencee

int-2f,int-2c co:G Peters,C Dickson ref:Y~hida, BBRC 1988; 157:618 BBRC 1988; 157:618 L381-M3 Yoshida J Virol 1989; 63:148 Morris kGRT39, XGRT6 J Virol 1990; 64:1794 tm~ae 39A, probe 6E Morris Nucl Acid Pea 1989; 17:4037 Brookes CO~16 ref:Hearne, M a m m Genome 1991; 1:273 MMINT2 (microsat) + co:JA Todd refiMontagutelli, M a m m Genome 1991; 1:255 (microsat) + co:JA Todd J Virol 1989; 63:1448 Peters (promoter/enhancer region) L40/2, MD/1, ~.779, S-S EMBO J 1988; 7:2035 Mansour Int-2, class A (= class B + additional 5' exon) class A eDNA EMBO J 1988; 7:2035 Int-2, class B dass B eDNA Mansour JNCI 1987; 78:327 Int-2 flank probe39A Pathak Virology 1987; 156:229 Schuermann Int-40 m a m m a r y tumor integration site-40 XMT40/1, p40/1 Virology 1987; 156:229 XaMT42/1, p42/1 Schuermann Nature 1983; 303:300 kallikrein gene family ~dVISP-I,LMSP-2,XMSP-3 Mason Kal Nature 1983; 303:300 kMSP-4,~.MSF-5,kMSP-6 M a s o n Nature 1983; 303:300 kMSP-7,XMSP-8,pK. 1.E5.0 M a s o n Nature 1983; 303:300 pK.I.B2.6, pK.1.EH.8, Mason Nature 1983; 303:300 pK.2.B.3, pK.2.BI.1, Mason Nature 1983; 303:300 pK.1.E.8.0, pMK-I,pMK-4 M a s o n DNA Cell Biol 1990; 9:737 mPK Seidah J Biol Chem 1982 257:2758 Richards pMK-1 + co:R Richards ref:Saunders, Genomic~ 1990; 8:525 Nucl Acid Res 1987; 15:10052 mGK-5 genomic Drinkwater Nucl Acid Res 1986; 14:4823 Fahnestock pMF-1, pMF-2 Nucl Acid Res 1988; 16:10918 mGK-11 genomic Drinkwater J Biol Chem 1988 263:8565 Drinkwater pMK-19 J Biol Chem 1987 262:8007 cMSP- 18,cMSF-8,cMSP-20, E v a n s J Biol Chem 1987 262:8027 cMSP-9,XMSP-67,kMSP-3, E v a n s J Biol Chem 1987 262:8027 ~VISP-35,1.MSP-62,kMS P- 1 E v a n s J Biol Chem 1987 262:8027 ZMSP- 25,2.MSP-36,LMSP- 14, Evans J Biol Chem 1987 262:8007 ikMSP-32,kMSP-2 7,kMSP-44, Evans J Biol Chem 1987 ; 262:8027 LMSP- 31,kMSP-61,LMSP-38, Evans J Biol Chem 1987 262:8027 kMSP-39,~.MSP-34,kMSP-23, Evans J Biol Chem 1987 262:8027 cMSP-16,cMSP-2,cMSP-7, E v a n s J Biol Chem 1987 262:8{}27 XMSP-33,cMSP-3,LMS P-69, E v a n s J Biol Chem 1987: 262:8027 Z24SP-8,kM S P-29,~.M S P- 43 E v a n s J Bid Chem 1987 262:8027 LMSP-28,LMSP-54,LMSP-53 Evans J Biol Chem 1987 262:8027 Z2dSP-2,LMSP-8,7~MSP-50, E v a n s J Biol Chem 1987: 262:8027 LMSP- 12,kMSP- 18,cMSP-21, Evans J Biol Chem 1987 262:8027 cMSP- 1,cMSP-22,LMSP-41, E v a n s J Biol Chem 1987: 262:8007 LMSP- 60,~.MSP-52,LMSP-56, Evans LMSP- 48,kMSP-45,kMSP-40, Evans J Biol Chem 1987: 262:8027 J Biol Chem 1987 262:8007 ZaMSP-66,kMSP-7,LMSP-21, E v a n s J Biol Chem 1987: 262:8027 LMSP-65,~.MSP-20,LMSP-2 4, Evans J Biol Chem 1987 262:8007 kMSP- 58,kMSP- 70,LMSP-3 0, Evans J Biol Chem 1987 262:8007 MMSP-47,Z.MSP-63,LMSP-5 7, Evans J Biol Chem 1987 282:8007 LMSP- 11,7~MSP-59,Z2r SP-49, Evans J Biol Chem 1987 282:8027 ikMSP-46,kMSP-3 7,~MSP-55, Evans J Biol Chem 1987 262:8007 kMSP-58,kMSP-42,kMSP-64 Evans ref:Hearne, M a m m Genome 1991; 1:273 MMKALL (microsat) + co:JA Todd L1Md-6(Hbb) L1 repeat in Hbb s haplotype ref:Shyman, Nucl Acid Res 19,85; 13:5085 L1Md-6 genomic co:M Garrick L1Md-9(Hbb) L1 repeat in Hbb d haplotype Ll(Hbb) Burton Nucl Acid Res 1985; 13:5071 Nucl Acid Ros 1985; 13:5085 BA3 Shyman Ldh-1 lactate dehydrogenase-1, A chain Ear J Biochem 1985; 149:215 kM15 co:Li Genetics 1987; 116:99 co:Li ref:Akai, Int J Biochem 198,5; 17:645 mA151 co:Li ref:Thomas, Development 1990; 109:483 co:Li J Genet Mol Biol 1990; 1:1 mA151 , LDH/A3' Hiraoka ref:Nikaido, Exp Cell Re~ 1991; 192:102 LG-2 co:AB Pardee ref:Hearne, M a m m Genome 1991; 1:273 MMLDHAG (microsat) + co:JA Todd Ldh-3 lactate dehydrogenase-3, chain C (sperm) mC31,mCS0 ref:Sakai, Bioehem J 1987; 242:619 co:Li ref:Thomaa, Development 1990; 109:483 mC31-1, LDH/C3' co:I Sakai BBRC 1987; 146:964 pLDH-X Wu Lhb luteinizing hormone co:M Tepper,JL Roberts refiKourides, PNAS 1984; 81:517 Lhb eDNA Fiddes Nature 1980, 286:684 [H] CGI~ eDNA Naylor Somatic Cell Mol Genet 1983; 9:757 [H] I3LH Saunders Genomics 1990; 6:324 Satmders Genomics 1990; 8:525 Ly-15 lymphocyte antigen-15 (= C D l l a , LFA-la) clone 28, clone 23 co:TA Springer ref:Kaufman, J Immunol 1991; 147:369 Ly-4S lymphocyte antigen-48 (see Cd43) Mag + D'Eustachio J Nearochem 1988; 50:589 myelin-associated giycoprotein [R] L-MAG Barton Genomies 1987; 1:107 [R] pMAG1.2 Arquint PNAS 1987; 84.~00 + co:Dunn (U Toronto) ref:Dickinson, Genomics 1990; 6:505 Fujita FEBS Lett 1988; 232:323 pMMAG1 Fujita BBRC 1989;, 165:1162 pMMAG4, pMMAG25, m a m m a r y tumor integration site-2

C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

350 Table 3. Continued, Chr Symbala

~

Name

7

Mag

myelin-associated glycoprotein

7

"Mns-7"

minor satellite Chr 7 (centromeric)

7

Mpmwl

7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7

RFLVc Coniac~t

pMMAG26 E007, E027, E657, E l l 0 [R] 5Mag pMR150

modified polytropic routine leukemia virus-1 JS-4 JH ~4s2-1-3-P2" minisatellite 2-1-3-P2 (human D1S57) pYNZ2 ~V!s2-2-14-Pl" minisatellite 2-2-14-P1 (human DIS57) pYNZ2 ~Ms2-2-15-P2" minisatellite 2-2-15-P2 (human D1S57) pYNZ2 ~Ms4-2-20-P2" minisatellite 4-2-20-P2 (human D2S44) pYNH24 ~[s4-1-4-Pl" minisatellite 4-1-4-P1 (human D2S44) pYNH24 ~Ms4-2-17-Pl" minisatellite 4-2-17-P1 (human D2S44) pYNH24 ~VIs5-2-10-P2" minisatellite 5-2-10-P2 pEWRB2.3 ~MsS-I-5-PI" minisatellite 5-1-5-P1 pEWRB2.3 "Ms5-1-6-P2" minisatellite 5-1-6-P2 pEWRB2.3 ~Ms5-2-11-PI" minisatellite 5-2-11-P1 pEWRB2.3 '2Vls5-2-7-Pl" minisatellite 5-2-7-P1 pEWRB2.3 "Ms8-1-1-PI" minisatellite 8-l-l-P1 (human INS) pINS310 "Ms8-2-11-P2" minisatellite 8-1-11-P2 (human INS) pINS310 '2VIs8-3-10-PI" minisatellite 8-3-10-P1 (human INS) pINS310 ~Ms8-3-13-P2" minisatellito 8-3-13-P2 (human INS) pINS310 ~IsS-l-2-P2" minisatellite 8-1-2-P2 (human INS) pIN,S~10 '2VIsl0-1-6-PI" minisatellite 10-1-6-P1 (human D17S5) pYNZ22 Mtv-I m a m m a r y tumor virus locus-1 IV] MMTV(C3H) 8-21

7

Mtv-35 Mylpf

7

Myod-i

m a m m a r y tumor virus locus-35 myosin light chain, fast skeletal muscle, phosphorylatable myogenic differentiation-1

Ngfa

nerve growth factor a

Ngfg

nerve growth factor 7

Oat Odc-rs8 Odc-rs7

ornithine aminotransferase ornithine decarboxylase related seq-6 ornithine decarboxylase related seq-7

Omp Otf-2

olfactory marker protein octamer-binding transcription factor-2

7

Probeb

pink-eye dilution (unstable allele)

+

+ + + + + + + + + + + + + + + + + + +

+ + + + + + + +

Fujita Nakano co:J Roder Voliva co:VM C h a p m a n co:ND Hastie Frankel co:W Frankel Julier Juliet Julier Julier Julier Julier Julier Julier Julier Julier Julier co:G Bell co:G Bell co:G Bell co:G Bell co:G Bell Julier

MacInnes Traina co:P D'Eustachio MMTV DNA co:J Ball, J Majors M M T V 8 - 2 I,MMTV8-29 Lee pTZISR-ORF co:JE Majors MMTVS', MMTV3' co:G Peters MMTV8-21 co:JE Majors [R] plO3 Katcoff Czosnek Myo D1 eDNA Davis Tapscott + co:AB Lassar + eo:AB Lassar [H] pV2Clla co:H Weintraub + co:AL Davis Myod- 1 genomic co:J-P Jest kMSP-19, EMSP-26 Evatls cMSP-16,cMSP-2,cMSP-7, Evans cMSP-3,kMSP-17,kMSP-51, Evans ~VISP-22,kMSP- 19,kMSP-26, Evans kMSP-50,kMSP- 12,kMSP- 18 Evans ~MSP-28,~.MSP-53,kMSP-6, Evans ~tAISP-22,%MSP- 19,)~ISP-26, Evans kMSP-28,~.MSP-53,XMSP-51 Evans ~MSP-6 Mason pSM676 + co:KW Gross + co:KW Gross cMSP- 16,cMSP-2,cMSP-7, Evans cMSP-3,kMSP- 17,kMSP-5 i, Evans kMSP-22,kMSP-28,XMSP-53 Evans :kMSP-22,~MSP-51, Evans ~vISP-28, ~r Evans MMNGFG2 (mierosat) + Montagutelli [H] OAT eDNA O'Donnell pMK3048 + co:RW Elliott pCR6 (pDOC934 derived) Rheaume + eo:FG Berger [R] k e M P Danciger Oct-2 eDNA Goldsborough mR2, mR4 Hatzopoulos [H] ).OB-C, %OB-B, kOB-A Muller [H] Puc-3-1 Ko + co:L Staudt [H] Otf-2 cDNA + Siracusa g23, p5 Stoykova Brillant 28RN + co:MH Brilliant

Ref~

e

BBRC 1989, 165:1162 BBRC 1991; 178:282 refiSaunders, Genomics 1990; 6:324 Nucl Acid ires 1983; 11:8847 ref:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1983; 11:6965 Genetics 1990; 124:221 ref:Gerstein, Cell 1990; 63:537 PNAS 1990; 87:4585 P N A S 1990; 87:4585 P N A S 1990; 87:4585 P N A S 1990; 87:4585 P N A S 1990; 87:4565 P N A S 1990; 87:4585 P N A S 1990; 87:4585 P N A S 1990; 87:4585 P N A S 1990; 87:4585 P N A S 1990; 87:4585 P N A S 1990; 87:4585 ref:Julier,P N A S 1990; 87:4585 ref:Julier,P N A S 1990; 87:4585 ref:Julier,P N A S 1990; 87:4585 ref:Julier,P N A S 1990; 87:4585 ref:Julier,P N A S 1990; 87:4585 P N A S 1990; 87:4565

Virology 1984; 132:12 J Virol 1981; 41:735 ref:Colombo, M a m m Genome 1992; 2:130 ref:MacInnes, Virology 1984; 132:12 J Virol 1990; 64:4568 ref:Pullen, J Exp Med 1992; 175:41 ref:Fairchild, Immunogenetics 1991; 34:227 ref:Siracusa, Genetics 1991; 127:169 PNAS 1980; 77:960 EMBOJ 1982; 1:1299 Cell 1987; 51:987 Science 1988; 242:40.5-411 ref:Cavanna, Genomics 1990; 7:12 tel:Kay, Gene 1991; 99:273 ref:Saunders, Genomics 1990; 8:525 tel:Colombo, M a m m Genome 1992; 2:130 ref:Zingg, Nucl Acid Res 1991; 19:6433 EMBO J 1985; 4:133 J Biol Chem 1987; 262:8027 J Biol Chem 1987; 262:8027 J Biol Chem 1987; 262:8027 J Biel Chem 1987; 262:8027 J Biol Chem 1987; 262:8027 EMBO J 1985; 4:133 EMBO J 1985; 4:133 Nature 1983; 303:300 ref:Howles, Nucl Acid Res 1984; 12:2791 ref:Saunders, Genomics 1990; 6:324 J Biol Chem 1987; 262:8027 J Biol Chem 1987; 262:8027 J Biol Chem 1987; 262:8027 EMBO J 1985; 4:133 EMBOJ 1985; 4.'133 M a m m Genome 1991; 1:255 A m J Hum Genet 1988; 43:922 ref:Richards-Smith, M:NL 1984; 7h46 Mol Endocrinol 1989; 3:1243 ref:Siracusa, Genetics 1991; 127:169 PNAS 1989; 86:8565 Nucl Acid Res 1990; 18:1634 Development 1990; 109:349 Nature 1988; 336:544 Cell 1988; 55:135 ref:Saunders, Genomics 1990; 8:525 Genomics 1991; 10:313 Neuron 1992; 8:541 Science 1991; 252:566 ref:Nakatau, M a m m Genome 1991; 2:69 Continued on next page

J.T.

Eppig: Clones and Probes

351

Table 3. Continued. Chr Symbala

7

7

7 7 7 7 7 7

7 7 7 7 7

I~cus Name

Probeb

RFLW C o n t ~

co:GS McKnight Ohno Wada Knopf [R] PMT-2PKC1 + co:JL Knopf Pkc)'probe (239 to 2304) Ohno Pkcc protein kinase C, T subunit Wada + co:Ullrich [H] PRKCG e D N A [H] phPKC-T6 + Saunders Pkcc probe + Bhatia po]ytropic murine leukemia virus-4 Pmv-4 JS-5 + Frankel + Frankel polytropie routine leukemia virus-15 JS-5 + Frankel Pmv-15 polytrepie murine leukemia virus-18 JS-5 + Frankel Pmv-18 pMo-MCFI-16 + co:M Vogt polytropic murine leukemia virus-29 J~5 + Frankel Pmv-29 polytropic murlne leukemia virus-31 JS-5 + Frankel Pmv-31 [R]rPTHs-I, [R]rPTHg- I Heinrich Pth parathyroid hormone Lalley [R] rPTHs-1 + co:G Heinrich + Noshiro regulation of phenobarbital-inducible P450 pf3, pf46 Rip + co:M Negishi Sparkes [H] RLBP1 eDNA Rlbpl retinaldehyde-binding protein 1 Sl6a, Sl6b, $16p,$16 cDNA W a g n e r Rps16 ribosomal protein $16 co:M Wagner SIGI2 pcD-rptl + Patarca Rpt- 1 regulatory protein, T lymphocyte-1 Patarca TR7-X, TR7-F2, TR7-D Lowe Harvey rat sarcoma oncogene,subgroup R kMR-9, kMR-7, LMR4, Rras Lowe ZaMR-14, ~d~lR-12 MR-9 + co:A Singh probe 1, pra~ 2 Brissenden ribonudeotide reductase M1 Rrml Carae p247, p201~I~-1 Caras pER-WT Caras Thelander clone 55 Caras Rrml m u t a n t eDNA ribonucleotiderednctase M 1 mutant Thelander Rrm2 eDNA Rrm2-ps2 ribonucleotide reductase M2, pseudo-2 Yang-Feng Koch homolog of rat transplantable antigen RT6 RT6 eDNA (PCR) Rt-6 + Prochazka Marks [RAB] Ryr eDNA muscle ryanodine receptor Ryr + Cavanna pRS48 + co:J Morrow serum amyloid A-1 Sam 1 Morrow Rienhoff Ishikawa pmSAP3 pSP-275 co:Meek Lowell San-1 genornic (done includes a pseudogene) Lowell Saa-2 genomie serum amyloid A-2 Saa -2 pRS48 Rienhoff co:Meek pSP-275 Lowell s e r u m amyloid A-3 San-3 genomic San-3 pSA415,pAA2 Rienhoff co:R Stearman pm~4s Rienhoff Lowell Saa-4 serum amyloid A-4 pseudogene (includes San-l) Saa-1 genomic Fresco Snrp2a U2 small nuclear ribonudeoprotein [H] A'910 + co:J Keene polypeptide 2A + co:LD Fresco Query [H] FL70K Snrp70 U1 small nuclear ribonucleoprotein + co:J Keene 70kDa polypeptide Levy target of antiproliferative antibody-1 mTAPA- 1 Tapa-1 co:S Levy " , Tapa-1 genomic telomere, Chr 7, p arm (TTAGGG)4 oligo + Kipling Tel7p Tgfb-1 transforming growth factor 13-1 pMur~2 Derynck co:R Derynck + co:R Derynck + co:R Derynck Pelton co:R Derynck Tglb-1 e D N A + co:R Derynck Tgfb-1 probe + Bhatia [H] pSV2gpt.hlns + Michalova transgene ( h u m a n insulin) "Tg74"

Pkcb

protein kinase C, ~ subunit

Pkcb genomie Pkc~ probe (-221 to 1963)

Referencee

refiChrivia, J Biol Chem 1988; 263:5739 Nature 1987; 325:161 BBRC 1989;, 155:533 Cell 1986, 46:491 ref:Pritchard, Genomics 1991; 10:801 Biochemistry 1988; 27:2083 BBRC 1989;, 165:533 ref:Cavanna, Genomics 1990; 7:12 Genomics 1990; 6 : 3 2 4 Oneogene 1991; 6:1569 J Virol 1989; 63:3810 M a m m Genome 1992; 2:110 J Virol 1989; 63:3810 J Virol 1989; 63:3810 res PNAS 1983; 80:6298 J Viro11989; 63:3810 J Viro11989; 63:3810 J Bio] Chem 1984; 259:3320 Cytogenet Cell Genet 1987; 44:92 ref:Satmders, Genomics 1990; 8:525 Biochemistry 1988; 27:6434 ref:Saunderu, Genomies 1990; 8:525 Oenomics 1992; 12:58 Mol Cell Biol 1985; 5:3560 ref:Wiedemann, Sore Cell Mol Gen 1987;13:77 PNAS 1988; 85:2733 PNAS 1988; 85:2733 Cell 1987; 48:137 Cell 1987; 48:137 ref:Saunders, Oenomics 1990; 8:525 Exp Cell Res 1988; 174:302 J Biol Chem 1985; 260:7015 Mol Cell Biol 1988; 8:2698 Mol Cell Biol 1988; 8:2698 Mol Cell Biol 1986; 6:3433 Mol Cell Biol 1988; 8:2698 Mol Cell Biol 1986; 6:3433 Genomics 1987; 1:77 Nucl Acid ICes 1990; 18:3636 Immunogenetics 1991; 33:152 PNAS 1989; 86:8683 Genomics 1990; 7:12 ref:Taylor, Mol Gen Genet 1984; 195:491 PNAS 1981; 78:4718 Mol Cell Biol 1988; 8:3710 N u d Acid Res 1987; 15:7186 re~Rienhoff, Mol Cell Biol 1988; 8:3710 J Bid Chem 1986; 261:8442 J Biol Chem 1986; 261:8442 Mol Cell Biol 1988; 8:3710 ref:Rienhoff, Mol Cell Biol 1988; 8:3710 J Biol Chem 1986; 261:8442 Mol Cell Biol 1988; 8:3710 ref:Saunders, Genomics 1990; 8:525 Mol Cell Biol 1988; 8:3710 J Biol Chem 1986; 261:8442 Mol Cell Biol 1987; 7:1148 ref:Saunde~, Genomies 1990; 8:525 ref:Colombo, M a m m Genome ~992; 2:130 Cell 1987; 51:211 ref:Saunders, Genomics 1990; 8:525 J Biol Chem 1991; 266:14597 ref:Andria, J Immunol 1991; 147:1030 Genomics 1991; 11:235 J Biol Chem 1986; 261:4377 refiFujii, Somatic Cell Genet 1986; 12:281 ref:Dickinson, Genomies 1990; 6:505 refiSatmders, Oenomies 1990; 8:525 Development 1990; 110:609 refiMillan, Development 1991; 111:131 refiCavanna, Genomics 1990; 7:12 Oncogene 1991; 6:1569 Hum Genet 1988; 80:247 C o n t i n u e d on next p a g e

LT. Eppig: Clones and Probes

352 Table 3. Continued. Chr Syrn~a

7

~

Name

Th

tyrosine hydroxylase

Tph

tryptophane hydroxylase

Tpi-3

tricsephosphate isomerase related seq-3

Tyr (c)

tyrosinase

from albino c/c (BALB/c mouse) from himilayan eh/ch mouse from chinchilla cch/cch mouse

Tyr~ 1 (deletion) (deletion) Xmmv-15 Xmmv-31 Xmv-30 Xmv-33 Xrce- 1 Zfp-36 Zp-2

xenotropic-MCF leukemia virus-15 xenotropic-MCF leukemia virus-31 xenotropic murine leukemia virus-30 xenotropie routine leukemia virus-33 X-ray repair complementing defective repair in Chinese hamster zinc finger protein-36 zona pellucida glycopretein-2

Ac~6

actin related gene-6

Adrb-3 Agt

adrenergic receptor, ~3-3 angiotensinogen

Probeb

RFLVc Contactd

[R] pHR3.0

+ co:Chikaraishi + Eicher [H] pHGTH4 O'M alley + Saunders [R] TH eDNA Grima co:Chikaraishi kTH-1, pTH1, pTH2, pTH3 co:T Nagatsu gMTH14, gMTH101 eo:T Nagatsu Tph eDNA + Stoll ~6, k7, ),2, kg, ),3, M1, Stoll M, k,5,M, X8 Stoll [H] pHTPI-5A Maquat + co:LE Maquat FixMTY-2, chMTY-1 Kwon PTY-2 Kwon PTY- 1 + Kwon PTY-1, [H]kmel34 Kwon [i-I] Pmel34 + Kwon [H] Pmel34 co:BS Kwon Tyrs-32, Tyrs-33 Yamamoto Tyrs-J2, Tyrs-J 19 Yamamoto pmeTyr I + Ruppert pmcTyr54, pmcTyr63 Ruppert pmcTyr 10, pmeTyr40 Ruppert pmcTyr20, pmcTyr24 Ruppert pmeTyr3, pmcTyrl8 Ruppert pmcTyr2, pmcTyr4 Ruppert MTY311, pMTYSllC, Kwon MTY 811C, PTY-1 Kwon MTY 811C Kwon + co:BSKwon + eo:BS Kwon + eo:BSKwon Ala, Alh, Alb.4, Ale.4, Porter Ald, Ald.3, Ald.4, A2.3.4, Porter A3, A3.4, A4, A1A3 Porter ~.AMTT3, ~.AMT75 Shibahara Tyr eDNA Kwon gTYR101, gTYR5, gTYR1, Ruppert gTYR2, gTYR14, gTYR31, Ruppert gTYR281, gTYR241, Ruppert gTYR161, gTYR123, Ruppert gTYR111,gTYR4,gTYR33, Ruppert gTYR30, pgTYRH4.8, Ruppert gTYRHS.0, pgTYRH1.8, Ruppert gTYRH0.9, pgTYRH2.2 Ruppert Tyr-1 eDNA Terao + Gonzalez p7.5(X/RI), p77-2, pH2.2H Sharan pE10.5cll, kE10.5cll Sharan pMo-MCFI-16 + co:M Vogt pMo-MCFI-16 + eo:M Vogt JS-6e/S-10 + Frankel JS-6r/S-10 + Frankel [H] XP1-30 Siciliano + co:L Thompson [R] cMG1, Zfp-36 clone Taylor pZP2.1,pZP2.2,pZP2.3,pZP2.4 Liang pZP2.4 + co:Liang [C] ~20(D Cleveland + Ceci Moil3, A43 Nahmias kMAI,~.gMA2,cMA2 cMA20,cMA18 pANG.71

Ank-I

erythroid specific ankyrin-1

exon 2 e D N A ~.Sw-50,XSw- 11,~Sw- 45 B A L B - A g t genomic mAnk-1

Aprt

adenine phosphoribosyl transferase

p S A M - 1 (=pSAM3.1)

pSAM3.1/24Sall

+ + + + + +

+ +

Clouston Clouston Clouston Clouston Clouston Clotmton Clouston White co:S Lux, R White Sikela co:P Stambrook Dush Turker co:Sikela

Refe~ncee

refiBrilliant, J Neurogenet 1987; 4:259 Genetics 1990; 125:431 Nuel Acid Res 1988; 16:4437 Genomic$1990; 8:525 PNAS 1985; 82:617 ref:Hess, Neuron 1991; 6:123 ref:Ichikawa, BBRC 1991; 176:1610 ref:BBRC 1992; 182:348 Genomics 1990; 7:88 J Neuresci Res 1991; 28:457 J Neuresci Res 1991; 28:457 J Biol Chem 1985; 260:3748 ref:Siraeusa, Genetics 1991; 127:169 J Invest Dermatol 1989; 93:589 J Invest Dermatel 1989; 93:589 J Invest Dermatol 1989; 93:589 PNAS 1987; 84:7473 PNAS 1987; 84:7473 ref:Barton, Genomics 1988; 3:17 Jpn J Genet 1987; 62:271 Jpn J Genet 1987; 62:271 EMBO J 1988; 7:2715 EMBO J 1988; 7:2715 EMBO J 1988; 7:2715 EMBO J 1988; 7:2715 EMBO J 1988; 7:2715 EMBO J 1988; 7:2715 BBRC 1988; 153:1301 BBRC 1988; 153:1301 BBRC 1989;, 161:252 refiLunsford, Genomics 1990; 6:184 ref:Dickinson, Genomics 1990; 6:505 ref:Saunders, Genomics 1990; 6:324 Gene 1991; 97:277 C-ene 1991; 97:277 Gene 1991; 97:277 E u r J Bib.hem 1990; 189:455 BBRC 1989;, 161:252 EMBO J 1988; 7:2715 EMBO J 1988; 7:2715 EMBO J 1988; 7'2715 EMBO J 1988; 7:2715 EMBO J 1988; 7:2715 EMBO J 1988; 7:2715 EMBO J 1988; 7:2715 EMBO J 1988; 7"2715 BBRC 1989; 159:848 DNA & Cell Biol 1990; 9:771 Genetics 1991; 129:825 Genetics 1991; 129:825 ref:Blatt, PNAS 1983; 80:6298 ref:Blatt, PNAS 1983; 80:6298 J Viro11989; 63:1763 J Virol 1989; 63:1763 Mutation Res 1986; 174:303 ref:Saunders, Genomics 1990; 8:525 Nuel Acid Res 1991; 19:3454 Mol Cell Biol 1990; 10:1507 ref: Lunsford, Genomics 1990; 6:184 Cell 1980; 20:95 Genomics 1990; 6:72 EMBO J 1991; 10:3721 Genomics 1988; 2:240 Genomics 1988; 2:240 Nucl Acid Res 1989; 17:822 FEBS Left 1989;, 255:419 EMBO J 1989; 8:3337 DNA Cell Biol 1990; 9:623 DNA Cell Biel 1990; 9:623 PNAS 1990; 87:3117 ref:Peters, J Cell Biol 1991; 154:1233 Gene 1983; 22:219 ref:Farber, Cytogenet Cell Genet 1986;42:198 PNAS 1985; 82:2731 Sore Cell Mol Genet 1989; 15:159 ref:Moen, Mamm Genome 1991; 1:217 Continued on next page

J.T. Eppig: Clones and Probes

353

Table 3. Continued. Symbola

8

Aprt

8

Aprt-ps

8

Ato~

8 8 8 8 8 8

BI(Um) By-1 C58v-1 Cadp Cph-1 Crry-ps

8

Ctrb

Locus Name

Probeb

RFLVc C o n ~ xl

adenine phosphoribosyl transferase

pill, pH2 Aprt cDNA-1,Aprt eDNA-2 ~Ylapl5, p15 p15 [CH] pHaprt-3 [CH] pHaprt-1 MMaprt-5, :kMaprt-11, ~Maprt- 12, ~.Maprt-13, ~,Maprt- 14, ~Maprt-15, MYlaprt-21, pMapr~-I 1, Aprt cDNA LMaprt- 15, pSam3.1 mAPRT-pucR1/SalI + adenine phosphoribosyl transferase, pseudo p15, kMapl5 ZMaprt- 15, pSam3.1 p15 + " + + probe 1, probe 2 + pSAM-1 (=pSAM3.1) + [CITI pHaprt-1 [CH] pHaprt-3 + MVlaprt-5, kMaprt-11, ~Maprt-12, ~Maprt-13, kMaprt-14, Z2clapr~-15, kMaprt-21, pMaprt- 11, Aprt cDNA ATPase, proton K+, 13polypeptide, gastric MG4, MG15A, MG15B lmb2, lmb3 B1 repeat within Um locus F20, F20B (withdrawn, = Emv-2) (withdrawn, = Emv-26) placental cadherin P3, P12, P13, P24, P21, P29 carboxypeptidase H [R] DG-1 + complement receptor related MScl.1, MScR1.0 protein Y pseudogene Crry-ps genomic chymotrypsinogen B [R] pcXP33 + +

8 8 8 8 8 8

"D8Hll" "DSMcC 1" D8Pasl D8Pas2 D8Fcrl Defcr Ecad Emv-2

DNA segment, Chr 8, HI1 cosmid Hll DNA segment, Chr 8, McClelland-1 AP-PCR oligo KB DNA segment, Chr 8, Pasteur Institute-1 unnamed DNA segment, Chr 8, Pasteur Institute-2 unnamed DNA segment, Chr 8, Frederick Cane Res-i OT24A4 defensin-related cryptdin peptide Defcr cDNA asb4/134 E-cadherin (see Urn, uvomorulin) endogenous ecotropic MuLV-2 IV] pEnv

+

endogenous ecotropic MuLV-26

Emv-29

endogenous ecotropic MuLV-29

Es-1

esterase- 1

Es-22

esterase-22

Fabph 2 Flt-2

fatty acid binding protein, heart-2 FMS-like tyrosine kinase-2

Gas-6

growth arrest specific-6

Gc-rs 1 Gnb-lrsl Gnb-4

(withdrawn, = Gnb-lrsl)

Nose Proehazka co:JH Weis Paul Bell Honey Watanabe co:GI Bell Boyle co:M McClelland Simon-Chazottes

EMBO J 1987; 6:3655 Mouse Genome 1991; 89:280 ref:Aegerter-Shaw, J Immunol 1987; 138:3488 J Immunol 1990; 144:1988 J Biol Chem 1984; 259:14265 Somatic Cell Mol Genet 1984; 10:377 Biochem Genet 1989; 27:119 ref:Scherer, GenomJcs 1989; 5:275 Genomics 1992; 12:106 ref:Welsh, Nucl Acid Res 1991; 19:5275 ref:Mattei, Oncogene 1990; 5:151 ref:Mattei, Oncogene 1990; 5:151 ref.'Ceci, Genomics 1990; 6:72 Genomics 1989; 5:233 J Cell Biol 1989; 108:1687

co:Lock Ou]lette Ou]lette

+

J Virol 1981; 43:26 co:NA J e n k i n s PNAS 1980; 77:5774 Chattvpadhyay PNAS 1980; 77:5579 Chan ref:Knight, Mol Cell Probes 1990; 4:497 co:BA Taylor Genomics 1989; 5:221 Taylor ref:Ceci, Genomics 1990; 6:72 co:S King Chattopadhyay PNAS 1980; 77:5774 Chan PNAS 1980; 77:5579 GenornJcs 1989; 5:221 Taylor PNAS 1980; 77:5774 Chattopadhyay PNAS 1980; 77:5579 Chan Genomics 1989; 5:221 Taylor co:Ovnic,Ganschow ref:Ceci, Genomics 1990; 6:72 Genomics 1991; 9:344 Ovnic Ovnic Genomics 1991; 9:344 ref:Ovnic, Genomics 1991; 11:956 co:TL Genetta Genornics 1991; 11:956 Ovnic Genomic8 1991; 11:956 Ovnic J Binl Chem 1987; 262:9709 Heuckeroth Oncogene 1988; 3:9 Ruta KIlO Oncogene 1991; 6:961 Cell 1988; 54:787 Schneider tel:Colombo, M a m m Genome 1992; 2:130 eo:P D'Eustachio Gennmics 1990; 7:509 Yang FEBS Lett 1985; 191:235 Sugimoto ref:Danciger, Genomics 1990; 6:428 co:M Simon (CIT)

+ + + + + + + + + +

Gas-6 cDNA-1 Gas-6 eDNA-2 group-specific component related seq-1 93[ guanine nucleotide bind prot-1 related seq-1 [B] ~.TBll2

Sore Cell Mol Genet 1989; 15:159 PNAS 1985; 82:2731 J Cell Biol 1983; 97:134a refiFarber, Cytogenet Cell Genet 1986;42:198 ref:Farber, Cytogenet Cell Genet 1986;42:198 ref:Sikela, Gene 1983; 22:219 Gene 1983; 22:219 Gene 1983; 22:219 Gene 1983; 22:219 Gene 1983; 22:219 Gene 1983; 22:219 Mol Cell Biol 1986; 6:4161 ref:Ceci, Genomics 1990; 6:72 J Cell Biol 1983; 97:134a Mo] Cell Biol 1986; 6:4161 ref:Farber, Cytogenet Cell Genet 1986;42:198 Mol Cell Biol 1986; 6:4161 ref:Ceei, Genomics 1990; 6:72 Mol Cell Biol 1986; 6:4161 Gene 1983; 22:219 refiFarber, Cytogenet Cell Genet 1986;42:198 ref:Sikela, Gene 1983; 22:219 ref:Farber, Cytogenet Cell Genet 1986;42:198 Gene 1983; 22:219 Gene 1983; 22:219 Gene 1983; 22:219 Gene 1983; 22:219 Gene 1983; 22:219 PNAS 1991; 88:8247 tel:Morley, J Biol Chem 1992; 267:1165 ref:Schuh, PNAS 1986; 83:1364

Simon-Chazottes

pEc-B4

Emv-26

Turker Dush Dush co:P Stambrook co:Taylor co:I Lowy Sikela Sikela Sikela Sikela Sikela Dush co:Strickland Dush Dush co:P Stambrook Dush co:Strickland Dush Sikela co:P Stambrook co:I Lowy co:Taylor Sikela Sikela Sikela Sikela Sikela Canfield co:IR vanDriel co:R Kemler

+ +

pEco peon, pEc-IM PN13 penn pEc-B4 peon, pEt-B4 pEco pEc-B4 pEco, pEc-B4 Egl clone A clones B, C, D, E pEST470 Ell El6 [R] H-FABP cDNA [H] Flt-2 cDNA

Refea~nmee

+ +

Continued on next page

J.T. Eppig: Clones and Probes

354 Table 3. Continued. Chr Symbola

8 8

Gr- 1 Hp

I~

Name

glutathione reductase- 1 haptoglobin

Pl~beb

RFLVc C ~ t ~

XGRM-BI I, pGRM-BI1 pHp + [HI phapto-6 +

8

lap(Agt)

intracisternal A particle,Agt linked

8

Insr

insulin receptor

8

Junb

Jun-B oncegene

XSw-I, %Sw-8 BALB-Agt genomic [H] phINSR14-1 kmIR1, %mIRB, %IRg8 pRINSR13-1 [I-I] pHIR [H] Insr PCR-Igf2r clone B31 junB cDNA

8

8 8

Jund

Kal-3 Lcat

Jun-D oncogene

kallikrein 3, plasma lecithin cholesterol acyltransferase

clone 465 Junb cDNA $5, $39, $42, S l l Jund cDNA (=$5?)

+

+ +

+ +

+ +

Jund cDNA [R] PK cDNA [HI LCAT 14A +

8

Lpl

lipopretein ]ipase

8 8

Lyl- 1 Mel

Lpl promoter, firstexon, firstintron lymphoblastic leukemia-i cellN K 1 4 derived transforming oncogene

MLCAT7 + mL5, mL31, m L l l m L l l , mL31 mL5 + XESI,kMG11,kMG9,~MG75 done 2123, clone 2127 pML3.5 + [HI PEmbl600

8

"Mns-8"

minor satellite Chr 8 (centromeric)

pMR150

8

Mov-34

Moloney leukemia virus-34

+

+

grz8

~1, ~.t5, ;.19, ~4, X38,:L34 8 8 8 8 8

Mpmv-21

modified polytropic routine leukemia virus-21

JS-4 JS-4 '~Msl-2-9-PI" minisatellite 1-2-9-P1 (Drosophila Per) pSP.2.5.EI ~Ms2-2-8-Pl" minisatellitc 2-2-8-P1 (human DIS57) pYNZ2 "Ms8-3-11-P2" minisatellito 8-3-11-P2 (human INS) pINS310 Mt-1 metallothionein-1 MlpFA.4

+ 4+ + + +

mMT-I + MIpEH.4, mek26, mm~.36 MIpEH.4, meX26 MIpEH.4, MlfdEH.4m, MlpSH1.3, MIpEE3.8 MIpSHI.3 Lmtl M135 pLIX1 + pKH +

8

Mr-2

metallothionein-2

Mtv-21

m a m m a r y tumor virus locus-21

Ox-1 Pcad

NAD(P)H menadione oxidoreductase-1 P cadherin

Pep-2

Purkinje cell protein-2

Mt-2 genornic, pAX Mt-2 cDNA, pKH mMT-II + MMMETII (microeat) + (micmsat) + Mtv21-5'C + Mtv21-3', Mtv21-5' Mtv21-3'C [R] Nine-1 cDNA + I~102, PG03, PG07, PG30 PG22, PG24, PG25, PG50 Pcad cDNA + PCDS, PCDS029

Tutic Baumann co:H B a u m a n n Raugei co:R Cortese Clouston Clouaten Wang Sibley Shaw co:Bell co:A Ullrich Ullrich Tel ford Hirai Mattei Matted Kuo Lau Ryder Hirai Mattei Kuo Ryder co:NG Seidah Tata co:S Humphries Warden Kirchgessner Kirchgessner Kirchgessner co'.J L Breelow co:JM Citable Kuo Padua Saunder Voliva co:VM Chapman co:ND Hastie Gridley Gridley Gridley Frankel Frankel Julier Julier co:G Bell co:RD Palmiter co:RD Palmiter co:RD Palmiter Durnam co:RD Palmiter co:RD Palmiter co:RD Palmiter co:RD Palmiter Brzezinski Mbikay co:Pavlakis Searle co:Searle Searle Searle eo:R Palmiter co:JA Todd co:JA Todd Peters Peters Peters Petersen eo:M Takeichi co:M Takeichi co:M Takeichi Nordquist

P,a f e ~ e e

Eur J Biochem 1990; 188:523 Mol Gen Genet 1985; 201:505 refiCeci, Genomics 1990; 6:72 Nucl Acid Res 1983; 11:5811 refiSeherer, Genomics 1989; 5:275 DNA Cell Biol 1990; 9:623 DNA Ceil Biol 1990; 9:623 Genomics 1988; 3:172 PNAS 1989; 86.~732 Nucl Acid Res 1985; 13:8661 ref:Ceci,Genomics 1990; 6:72 ref:Colombo, M a m m Genome 1992; 2:130 Nature 1985;313:756 Mol Reprod Devel 1990:27:81 EMBO J 1989; 8:1433 Oncogene 1990; 5:151 Oncogene 1990; 5:151 Oncogene 1991; 6:961 PNAS 1987; 84:1182 PNAS 1988; 85:1487 EMBO J 1989; 8:1433 Oneogene 1990; 5:151 Oncogene 1991; 6:961 PNAS 1989; 86:1500 ref:Beaubien, Biochemistry 1991; 30:1628 BBA 1987; 910:.142 ref:Scherer, Genomics 1989; 5:275 J Biol Chem 1989; 264:21573 J Biol Chem 1987; 262:8463 J Biol Chem 1989; 264:1473 J Biol Chem 1989; 264:1473 refiZechner, Genomics 1991; 11:62 ref.'Hua, Gene 1991; 107:247 Oncogene 1991; 6:961 Nature 1984; 311:671 Genomics 1990; 8:525 Nucl Acid Res 1983; 11:8847 refiBroccoli, Cytogenet Cell Genet 1990; 54:182 reflPietras, Nuci Acid Res 1983; 11:6965 Development 1990; 109:235 Development 1990; 109:235 Genomics 1991; 11:501 Genetics 1990; 124:221 M a m m Genome 1992; 2:110 PNAS 1990; 87:4585 PNAS 1990; 87:4585 ref'Julier, PNAS 1990; 87:4585 ref:Watanabe, Biochem Goner 1989; 27:689 refiAzen, Genomics 1989; 5:415 ref:Scherer, Genomics 1989; 5:275 PNAS 1980; 77:6511 ref:Glanville, Nature 1981; 292:267 ref.'Beach, PNAS 1981; 78:2110 refiBeach, PNAS 1981; 78:2110 refiCax, H u m Genet 1984; 64:61 Cytobios 1987; 52:33 BBRC 1981; 103:825 ref:Ceci, Genomics 1990; 6:72 Mol Cell Biol 1984; 4:1221 refiOvnic, Genomics 1991; 11:956 Mol Cell Biol 1984; 4:1221 Mol Cell Biol 1984; 4:1221 ref:Watanabe, Biochem Genet 1989; 27:689 ref:Hearne, Mamin Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 J Virol 1986; 59:535 J Virol 1986; 59:535 J Virol 1986; 59:535 PNAS 1989; 86:6699 ref:Hatta, Nucl Acid Rcs 1991; 19:4437 refiHatta, Nuci Acid Res 1991; 19:4437 refiHatta, Nucl Acid Res 1991; 19:4437 J Neuresci 1988; 8:4780 Continued on next page

355

J.T. Eppig: Clones and Probes Table 3. Continued. Chr S~nl~ a

~

Name

8

Plat

plasminogen activator, tissue

8

Pmv-10

polytropic murine leukemia virus-10

8

Polb

DNA po]ymerase

8

Psx-8 Tat

(withdrawn, gee D8Ferl) tyrosine aminotransferase

8

8 8 8

Tea T-cell early activation gene " T g - M y c " Myc/SV40 promoter transgene insertion Ucp mitochondrial uncoupling protein

8

Um

uvomorulin

8 8 8

Xmmv-29 Xmv-12 Xmv-26

8

zrp-1

xenotrepic-MCF leukemia virus-29 xenotropic murine leukemia virus-12 xenotrepic murine leukemia virus-26 zinc finger protein-1

8

Zfp-4

zinc finger protein-4

Probeb

co:P,J Riekles Huarte Huarte Rickles eo:Rickles eo:S Strickland co:S Strickland co:S Strickland co:S Strickland co:RJ Riekles Frankel Frankel Yamaguchi McBride McBride co:JA Todd

ref:Huarte, Genes & Devel 1987; 1:1201 Genes & Devel 1987; 1:1201 Genes & Devel 1987; 1:1201 J Biol Chem 1988; 263:1563 tel:Rajput, Som Cell Mol Genet 1987; 13:581 tel:White, PNAS 1990; 87:3117 refiCeci, Genemics 1990; 6:72 refiFrankel, M a m m Genome 1992; 2:110 tel:Boyle, Genomics 1992; 12:106 ref.'Celombo, M a m m Geneme 1992; 2:130 J Viro11989; 63:3810 M a m m Genome 1992; 2:110 Mol Cell Biol 1987; 7:2012 Cytogenet Cell Genet 1990; 53:108 Cytogenet Cell Genet 1990; 53:108 ref:Hearne, M a m m Genome 1991; i: 273

pmTAT-SH3.7

Muller co:G Schutz Schmid co:G Schutz Muller Muller Scherer Muller Hashimoto Hashimoto Muller MacLeod B e e r m a nn co:LP Kozak Kozak co:LP Kozak co:LP Kozak Ringwald co:R Kemier co:R Kemler co:R Kemler co:Ringwald,Kemler co:R Kemier co:R Kemler co:Vogt Frankel Frankel Chowdhury Chowdhury Chowdhury Nadeau eo:Willison Ashworth co:K Willison Nadeau eo:J Boulter (Salk) eo:J Patrick co:J Patrick co'J Patrick Birkenmeier co:RW Elliott eo:AJ Kinniburgh co:Kinniburgh 2 -Ki nniburgh Williams Williams Frank Buchberg Nanba co:K Suzuki co:BF Tack co:BF Tack Saris Saris Regnier Ballantyne Friedman co:J Friedman co:J Friedman

J Mol Biol 1985; 184:367 ref:Scherer, Genomics 1989; 5:275 PNAS 1985; 82:2866 ref:Eistetter, PNAS 1988; 85:3489 J Mol Biol 1985; 184:367 J Mol Biol 1985; 184:367 PNAS 1982; 79:7205 J Mol Biol 1985; 184:367 PNAS 1984; 81:6637 PNAS 1984; 81:6637 J Mol Biol 1985; 184:367 Mol Cell Biol 1990; 10:3663 Cytogenet Cell Genet 1988; 49:311 ref:Jacobsson, J Biol Chem 1985; 260:16250 J Biol Chem 1988; 263:12274 ref:Ceci, Genomics 1990; 6:72 refiOvnic, Genomics 1991; 11:956 EMBO J 1987; 6:3647 ref:Eistetter, PNAS 1988; 85:3489 ref:Eistetter, PNAS 1988; 85:3489 ref:Scherer, Genomics 1989; 5:275 ref:Hatta, Nucl Acid Res 1991; 19:4437 res PNAS 1986; 83:1364 ref:Ringwald, Nucl Acid Res 1991; 19:6533 ref:Blatt, PNAS 1983; 80:6298 J Virol 1989; 63:1763 J Virol 1989; 63:1763 Cell 1987; 48:771 Nucl Acid Res 1989; 17:10427 Nucl Acid Res 1989; 17:10427 Genomics 1990; 8:489 1st Inter Worksh on Mouse Gene Map 1987 Genomics 1989; 4:323 ref:Ceci, Genomics 1990; 6:72 Genomics 1990; 8:469 ref:Bessis, FEBS Lett 1990; 264:48 ref:Eng, Genemics 1998; 9:278 ref:Eng, Genomics 1998; 9:278 refiEng, Genomics 1998; 9:278 PNAS 1986; 83:2516 ref:Miller, PNAS 1983; 80:1511 personal communication personal communication Nucl Acid Res 1985; 13:1953 Mol Cell Biol 1986; 6:3807 Mol Cell Biol 1986; 6:3807 Genomics 1989; 5:646 Nucl Acid Res 1985; 13:1953 BBRC 1990; 173:141 ref:Nanba, BBRC 1991; 178:158 refiAmiguet, Biochemistry 1990; 29:1226 ref:Amiguet, Biochemistry 1990; 29:1226 Cell 1986; 46:201 Cell 1986; 46:201 J Virology 1989; 63:3678 Genomics 1991; 9:547 Genomics 1989; 5:463 tel:Kingsley, Genetics 1989; 123:165 ref:Boyle, Genomics 1992; 12:106

aeetyleholine receptor a3, neural

[R] PCA46E(3)

9 9 9

Acra-5 Acrb-4 Apoa- 1

acetylcholine receptor aS, neural aeetylcholine receptor ~4, neural apolipopretein A-I

9

Apoa-4

apolipoprotein A-IV

[R] pCA989E [R] pZPC13 pMI4 p1804 pBAH-I pApoA-IV FL-3

~-galactosidase complex

9

Callh

ealpactin I heavy chain

9

Cbl-2

Casitas B-lineage lymphoma-2

9

Cek

cholecystokinin

+ +

SH3.7,HE2.1,ES1.4 Tat genomic + ).mTAT-1, pmTAT-PE0.6 pmTAT-EA0.65 [R] pcTAT-3 " [R] krTAT1 [R] prTAT-EE 1.05 " clone 20.5 + pSvc-myc- 1 pCIN-1 + pUCP1, pUCP2 pUCP-G4 + + F5, FSH3, F20, F2OA FS, UC,4 FSH3 + + + F20, F20A, F20B UG1, UG2, UG3, UG5 pMo-MCFI-16 + JS-6flS-10 + JS-6flS-10 + kmkrl, Zfp-1 eDNA c3 cl + pKC7 + pmFP2 +

Acra-3

Bgl

Regevencee

pUC9-A33 pSP65-MT 1 pSP64-MT2, pSP64-MT 3 Ck2, CkEPE pE]~ pTAMS0 + + + c47 pTAM2.5 + JS-5 + kMGB01 [R] Polb eDNA + [I-I] Polb-hu eDNA + MPOLB (microsat) +

9

9

RFLVc Conlactd

Apes-4 eDNA, Apes-4 genomic Apoa-4 eDNA p17 BGL eDNA cos28, ces49, cos52, ces3 RW22, B34 clone 123 clone C l l , 9B-64 cloen 123, clone 178 v-cbl probe 2 " Cck.b5

+ + + +

+

+ + + +

BamS~.74

Continued on next page

356

J.T. Eppig: Clones and Probes

Table 3. Continued. Chr Symbola

9

9

9 9

9

9

9 9

Cp

Locus Name

ceruloplasmin

Prcbeb

RFLVc Caltac~t

[R] kRCP-I, [R] kRCP-2 Schwartzman JR] kRCP-3 Schwartzman [R] ~RCp-1, [R] ~Cp-2, Baranov [R] kRCp-3, [R] pRCp-2 Baranov [R] kRCP-1, [R] kRCP-2 Baranov [R] :k~RCP-3,[R] pRC-02 Baranov Crbp cellular retinol binding protein [R] pCRBP + co:JI Gordon pG2AVP Perez-Castro Crbp genomic W ei mCRBPI, CRBP25 Smith Crbp-2 cellular retinol binding protein II [R] pCRPII + co:JI Gordon Cyplal cytochrome P450, l a l , aromatic carbon pP1-450FL + co:Simmons inducible " Hildebrand Kimura co:DW Nebert kB6P1450-34 co:DW Nebert " co:DW Nebert pP1-450-57 Tukey proP1-450-3' Kimura P450-1 Fmbe + Friedman clone 46 + co:DW Nebert C y p l a l cDNA(cl mutant) K i m u r a Cyplal cDNA(c37 mutant) K i m u r a MMMOPC (microsat) , co:JA Todd Cypla2 cytochrome P450, la2, aromatic carbon pP3-450FL co:Simmons inducible + co: EH Leiter + co:Nebert Kimura Kimura + co:Nebert co:DW Nebert kB6P1450-15 co:DW Nebert " co:DW Nebert C57BIJ6N P3-450 cDNA Kirnura DI~A]2N P2-450 cDNA Kimura pP345G21 Tukey M M C Y O 3 (microsat) + co'JA Todd (micm~at) + co:JA Todd Cyplla cytochrome P450, l l a , cholesterol side [R] P450-scc + co: JS Richards chain cleavage C y p l l a genomic Rice Cyp19 cytochrome P450, 19, a m m a t a s e [H] P450-arom + co:AJ Mason gES-M10, pES-M1, pES-M0 Terashima d dilute (=Emv-3) p.Emv-3, %.Emv-3 Copeland d-genomic, d-+2J genomic Copeland d-+Ha genomic, pEco Copeland Pstl subclone + Copeland IV] pEnv + Jenkins + Jenkins p0.3 + Rinchik " + co:NG Copeland " + co:NG Copeland d-120J genomic, d c D N A co:NG Copeland d-v genomic, d genomic co:NG Copeland kDSE-RI(D), k.Emv-3 Rinchik pRI.3, pO.5, pOX, pAfAa2 Rinchik p04.1 + Rinchik pDSE-94,1 Rinchik env probe Rinchik pGTI04-2 + co:Separak pEco Chattopadhyay pEc-B4 Chan p e t e , pF~B4 + Taylor D3F15S2h DNA segment, Chr 9, h u m a n D3F15S2 (see Hgfl) D3S92h DNA segment, Chr 9, h u m a n D3S92 []-I]anonymous D3S92 Lalley D3S93h DNA segment, Chr 9, h u m a n D3S93 [H] anonymous D3S93 Lalley D9Ag3 DNA segment, Chr 9, Agouron Inst, brain [R]lB1075 + Blatt + co:Ottinger "D9H 14" DNA segment, Chr 9, H 14 cosmid HI4 Boyle "D9Haml" DNA segment, Chr 9, Hamburg-1 p15-4 Harbers D9Lehl DNA segment, Chr 9, Lehrach-1 B1 SINE (GATA)3 + Cox D9Ndsl DNA segment, Chr 9, Nuffield Dept Surg-1 MMRSY (microset) + co:JA Todd D9Rtil DNA segment, Cbr 9, Res Triangle last-1 pMEI + Cobb

P,desmcee

Mol Biol (Mosk) 1985; 19:496 Mol Biol (Mesk) 1985; 19:496 Genetika 1985; 21:409 Genetika 1985; 21:409 Chromosoma 1987; 96:60 Chromesoma 1987; 98:60 refiDemmer, J Biol Chem 1987; 262:2458 PNAS 1989; 86".8813 DNA Cell Biol 1990; 9:471 EMBO J 1991; 10:.2223 ref.'I)emmer, J Biol Chem 1987; 262:2458 J Biol Chem 1983; 258:9585 BBRC 1985; 130:.396 J Biol Chem 1984; 259:10705 ref:Gonzalez, Gene 1984; 29:281 ref:Gonzalez, Gene 1984; 29:281 refiGonzalez, J Biol Chem 1985; 260:5040 PNAS 1984; 81:3163 EMBO J 1987; 6:1929 Genomics 1989; 5:463 ref: Youngblood, Endocrinology 1989; 125:2784 EMBO J 1987; 6:1929 EMBO J 1987; 8:1929 ref:Hesrne, M a m m Genome 1991; 1:273 J Biol Chem 1983; 258:9585 ref:Prochazka, Science 1987; 237:286 ref:Hildebrand, BBRC 1985; 130:398 Nucl Acid Res 1984; 12:2917 J Bio] Chem 1984; 259:10705 ref: Kingsley, Genetics 1989; 123:165 ref:Gonzalez, Gene 1984; 29:281 ref:Gonzalez, Gene 1984; 29:281 refiGonzalez, J Biol Chem 1985; 260:5040 Nucl Acid Res 1986; 14:5765 Nucl Acid Res 1986; 14:6765 PNAS 1984; 81"3163 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 ref: Yeungblood, Endocrinology 1989; 125:2784 J Biol Chem 1990; 265:11713 ref: Yeungblood, Endocrinology 1989; 125:2784 Archives Biochem Biophys 1991; 285:231 Cell 1983; 33:379 Cell 1983; 33".379 Cell 1983; 33:379 Cell 1983; 33:379 J Virol 1981; 43:26 Nature 1981; 293:370 Genetics 1986; 112:321 refiMoore, Genetics 1988; 119:933 refiMoore, PNAS 1988; 85:8131 refiMoore, PNAS 1988; 85:8131 refiMoore, PNAS 1988; 85:8131 Genetics 1986; 112:321 Genetics 1986; 112:321 Genetics 1986; 112:321 Genomics 1989; 4:251 Genomics 1989; 4:251 ref: Kingsley, Genetics 1989; 123:165 PNAS 1980; 77:5774 PNAS 1980; 77:5579 Genomics 1989; 5:221 Cytogenet Cell Genet 1989;, 51:1028 Cytogenet Cell Genet 1989;, 51:1028 Cytogenet Cell Genet 1985; 40:583 refiKingsley, EMBO J 1990; 9:395 Genomics 1992; 12:106 Cytogenet Cell Genet 1990;, 53:129 Genomics 1991; 10:375 ref:Hearne, M a m m Genome 1991; 1:273 Genomies 1992; 12:405 Continued on next page

J.T. Eppig: Clones and Probes

357

Table 3. Continued, Chr ~ 1

a

9

Epor

9

Ets-1

9

Fli-I

9

Gnai-2

9

Gnat-1

L~cus Name

erythropoietin receptor

Probeb

RFLVc Cnntac~

Youssoufian clone 190, clone 141 D'Andrea EPOR eDNA (eo:elonel90)+ B u d a r f pMER2-1, pMER27-1, Kuramoehi pMER13-1, ~MGER4 Kuramochi E26 avian leukemia oncogene-1, 5' domain [HI pRD700 Watson IV] E1.28 Watson [HI pRD700, [HI H33 co:SJ O'Brien mEtsl00a Reeves + co:Reeves clone D, clone E Chen Friend leukemia integration-1 probe B1, l:rmbe B3 Ben-David XC1, ~.C~ Ben-David probe B2 + Ben-David B4 genomic, BB4 cDNA Ben-David guanine nucleotide binding protein, [HI Gnai-2 eDNA Sparkes a inhibiting-2 [R] Gnai-2 cDNA Jones Blatt pGM1.3 co:HR Bourne Ashley + co:Masters guanine nueleotide binding protein, [B] pTal3 Tanabe a transducing-1 (rod transducin) [B] T a l (from pTal3) co:MI Simon Farber

9

9

Gs~2 Gsta

alpha glutathione S transferase 2 cluster glutathione-S-transferase Ya subunit

clone 2a, clone 16b [HI Gnat-1 eDNA [HI pGST2-PvuII [R] plasmid A24

+ +

3.mYa 1

9

Hgfl

hepatocyte growth factor-like protein

9 9

Icam-I Ldlr

(withdrawn, see Ly-47) low density lipoprotein receptor

kmL1, kmL3,~mL7,kmL8 clone 4.1 pMLS-2, pMLS-2/740 Hgfl genomic [CH]pV79-1 + [H] pLDLR

[B] pLDLR-1 Ltf

Lvs

lactotransferrin

Ly-47

lacking vigorous sperm transgene insert at Lvs lymphocyte antigen-47 (= Icam-1)

9

Mine

membrane metallo endopeptidase

9 9

Mmv-20 "Mns-9"

MCF endogenous virus-20 minor satellite Chr 9 (centromeric)

9

Mod-1

malic enzyme, s u p e r n a t a n t

9 9 9 9 9 9 9

Lochrie co:M Lochrie Raport Sparkes Kasahara Daniel co:Daniel co:V Daniel Daniel Daniel co:V Daniel co:DL Eaton Degen Degen

Mol Cell Biol 1990; 10:3675 Cell 1989;, 58:1023 Genomics 1990; 8:575 J Mol Biol 1990; 216:567 J Mol Biol 1990; 216:587 Anticanc Res 1986; 6:631 Anticanc Res 1986; 6:631 refiWatson, PNAS 1986; 83:1792 unpublished ref." Kingeley, Genetics 1989; 123:165 Oncogene Res 1990; 5:277 PNAS 1990; 87:1332 PNAS 1990; 87:1332 PNAS 1990; 87:1332 Genes Develop 1991; 5:908 Cytogenet Cell Genet 1985; 46:696 J Biol Chem 1987; 262:14241 PNAS 1988; 85:7642 ref:Sullivan, PNAS 1986; 83:6687 J Biol Chem 1987; 262:15299 ref: Kingsley, Genetics 1989; 123:165 Nature 1985; 315:242 ref.'Danciger, Genomics 1989,; 4:215 In:Inherited and Environmentally Induced Retinal Degenerations, Alan Liss, 1989; 143 Science 1985; 228:96 rof:Blatt, PNAS 1988; 85:7642 J Biol Chem 1989; 264:7122 Cytogenet Ceil Genet 1985; 40:696 Genomics 1990; 8:90 Arch Biochem Biophys 1983; 227:261 ref:Kingsley, Genetics 1989; 123:165 res Nucl Acid Res 1984; 12:4825 DNA 1987; 6:317 Nucl Acid Res 1988; 16:351 ref:Czosnek, Nucl Acid Res 1984; 12:4825 ref:TM Buetler, Cane Res 1992; 52:314 Biochemistry 1991; 30:9781 Biochemistry 1991; 30:9781

Sege co:Krieger co:D Russell Russell Frank Teng Teng eo:CT Teng Friedman Shirsat Magram Magram Ballantyne Ballantyne Horley co:A Brian co:AA Brian Shapiro Shapiro Frankel Voliva co:VM C h a p m a n co:ND Hastie Sul Sul Cobb Cobb co:CR Rubin Frankel Julier Julier Julier Julier Julier Julier

Mol Cell Biol 1986; 6:3268 ref:Kingeley, Genetics 1989; 123:165 refiWang, Genomics 1988; 3:172 PNAS 1983; 80:7501 Genomics 1989; 5:646 Biochem J 1986; 240:413 Somatic Cell Mol Genet 1987; 13:689 ref:Liu, J Biol Chem 1991; 266:21880 Blood 1991; 78:2426 Gene 1992; 110:229 PNAS 1991; 88:10327 FNAS 1991; 68:10327 Nuel Acid Res 1989; 17:5853 Genomics 1991; 9:547 EMBO J 1989; 8:2889 ref:Satmder, Genomics 1990; 8:525 ref:Siu, J Immunol 1989; 143:3813 J Biel Chem 1992; 267:4684 J Biol Chem 1992; 267:4664 M a m m Genome 1992; 2:110 Nucl Acid Res 1983; 11:8847 ref:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nuel Acid Res 1983; 11:6965 J Biol Chem 1984; 259:555 J Biol Chem 1984; 259:558 Mutation Res 1990; 234:1 Genomics 1992; 12:405 re~Coleman, J Biol C h e m 1991; 266:21997 Genetics 1990; 124:221 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585

~.11

[B] Gnat-1 eDNA

" pT267

+

kJ14, mL14p9E, mL14pSE LF eDNA LTF-A, LTF-B Lvs genomic pIsh Ly-47 eDNA + K1-8, K3-1.1, K4-1.1 Icam-1 eDNA + ~cSe, ICAM-1 genomic MME cDNA + MME genomic MCF100 + pMR150 pME1, pME2, pME3, pME4, pME5, pME6 pME1 (mutant vs. +)

Mod-1 probe Mpmv-27 modified polytropie murine leukemia virus-27 JS~4 "Msl-2-5-PI" minisatellite 1-2-5-P1 (Drosophila Per) pSP.2.5.EI "Ms2-3-3-Pl" minisatellite 2-3-3-P1 (human D1S57) pYNZ2 ~Ms2-2-6-P2" minisatellite 2-2-6-P2 (human D1S57) pYNZ2 "Ms3-1-3-PI" minisatellite 3-1-3-P1 (human D3S45) pEFD134.7 "Ms3-1-4-P2" minisatellite 3-1-4-P2 (haman D3S45) pEFD134.7 ~Yls3-2-9-Pl" minisatellite 3-2-9-P1 (haman D3S45) pEFD134.7

+ + + + + + + + + +

Refe~ce e

Continued on next page

J.T. Eppig: Clones and Probes

358 Table 3. Continued. Chr Symbola

LocusName

Probeb

RFLVc Cantac~

9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9 9

Julier Julier Julier Julier Juliet Juliet Julier co:T Dryja co:T Dryja eo:G Bell Julier Julier Julier Julier Julier Julier co:Buckingham co:Robert Robert Barton Barton Sola co:P D'Eustachio D'Eustachio Barthels Goridis Goridis co:C Goridis co:C Goridis Santoni Santoni Santoni Santoni Barthels co'JA Todd co:JA Todd Rheaume + co:FG Berger octamer-binding transcription factor tel seq-9 Oct-4 cDNA 4co:K Artzt preproenkephalin L2S35 Kwon pMTP6, Pen]{ cDNA Kilpatrick Penk genomic Shapiro progesterone receptor mPR-2 Shyamala [H] hPR-54 co:BW O'Malley mPR1, mPR2, mPR10, co:G Shyamala mPRll, mPR13, mPR14 eo:G Shyamala poliovirus sensitivity [H] PVS DNA Siddique + eo:V Racanie]lo retinoic acid binding pretein-5, cellular pLNWX, pLNWY Perez-Castro MoTCAll Vaessen U1 small nuclear RNA-2 Rnul-2 DNA Uoussa T35 chain ~.PEM-T35, pPEM-T35 VandenElsen pPEM-T3r pPEM-T35 VandenElsen pPEM + co:DP Gold 55A10, 4A10, 19A10 co:B Malissen MMCD3DEN (micresat) + co:JA Todd (micmsat)+ co:JA Todd T3e chain tiff] pDJ1, [H] 5a.2 Gold [HI pDJ1 Gold 33A10, 12.1AI0, 19A10 co:B Malissen pDL1 Gold + co:C Terhorst + co:DP Gold clone pSVL-em Berkhout pEl, pE2, pE3, pE4 Clevers T3T chain pB10.AT3-T1 co:MJ Crumpton co:MJ Crumpton co:MJ Crumpton 57.2BIOA, 52.3B10A, co:B Malissen 45.3BIOA, 58A10 co:B Malissen [H] pJ6T3T-2 Krissansen pB10.AT3T1 Krissansen pT134, pT118 Haser

9

"Ms3-2-10-P2" minisatellite 3-2-10-P2 (human D3S45) pEFD134.7 + "Ms3-3-13-Pl" minisatellite 3-3-13-P1 (human D3S45) pEFD134.7 + "Ms3-3-14-P2" minisatellite 3-3-14-P2 (human D3S45) pEFD134.7 + "Ms4-2-9-Pl" minisatellito 4-2-9-P1 (human D2S44) pYNH24 + "Ms4-3-10-PI" minisatellite 4-3-10-P1 (human D2S44) pYNH24 + "Ms4-1-8-P2" minisatellite 4-1-8-P2 (human D2S44) pYN'H24 + "Ms4-1-9-PI" minisatellite 4-1-9-P1 (human D2S44) pYNH24 + "Ms7-1-8-P2" minisatellite 7-1-8-P2 (human RB1) p68RS2.0 + "Ms7-2-15-P2" minisatellite 7-2-15-P2 (human RB1) p68RS2.0 + "MsS-2-8-P2" minisatellite 8-2-8-P2 (human INS) pINS310 + "Msl0-1-3-P2" minisatellite 10-1-3-P2 (human D17S5) pYNZ22 + "Msl0-1-4-PI" minisatellite 10-1-4-P1 (human D17S5) pYNZ22 + "Msl0-2-1-P2" minisatellite 10-2-1-P2 (human D17S5) pYNZ22 + "Msl0-2-2-PI" minisatellite 10-2-2-P1 (human D17S5) pYNZ22 + "Msl0-3-2-PI" minisatellite 10-3-2-P1 (human D17S5) pYNZ22 + "Msll-I-5-P2" minisatellite 11-1-5-P2 (human D17S24) pRMU3 + Mylc myosin light chain, alkali, cardiac pA29 + ventricles Mylc probe + pG~ pGLC450, kVLCi ~29 + MLCIA Ncam neural cell adhesion molecule p~l + kmN1, pECS02 A14, N22 M1, pM1.3, M2, pM2.2, M3, pM3.7 pM1.3, pM3.7 pM1.3 + NM, HB4, 4.1, 3.1, B22, Bg~, ag2, 3SFA DW1, DW2, DW42, DW60, DW61 DW3,M9,5.7c, 3SEA MMNCAMIA (microsat) + (nficrosat) + Odc-rsl4 ornithine decarboxylase-related seq-14 pCR6 (pDOC934 derived)

9 9

Otf3-rs9 Penk

9

Pgr

9

Pvs

9

Rbp-5

9 9

Rnul-2 T3d

9

T3e

9

T3g

9

Refe~e~ee

PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4585 tel:Juliet, PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 ref:Robert, Nature 1985; 314:181 Nature 1985; 314:181 personal communication J Biol Chem 1985; 260:8578 J Biol Chem 1985; 260:8578 J Vire11988; 62:3973 PNAS 1985; 82:7631 PNAS 1985; 82:7631 Nuci Acid Res 1988; 16:4217 EMBO J 1985; 4:631 EMBOJ 1985; 4:631 ref:Nguyen, J Cell Biol 1986; 102:711 ref:Moen, Maram Genome 1991; 1:217 Nucl Acid Res 1987; 15:8621 Nucl Acid Ras 1987; 15:8621 Nucl Acid Res 1987; 15:8621 Nucl Acid Ras 1987; 15:8621 EMBO J 1987; 6:907 ref:Hearne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 Mol Endocrinol 1989; 3:1243 ref:Siractma, Genetics 1991; 127:169 ref:Yeom, Mech Devel 1991; 35:171 PNAS 1989; 86:1963 Mol Cell Biol 1990; 10:3717 J Biol Chem 1992; 267:4664 Endocrinology 1990; 126:2882 ref:Shyamala, Endocrinology 1990; 126:2882 ref:Schott, Biochemistry 1991; 30:7014 ref:Schott, Biochemistry 1991; 30:7014 Genomics 1988; 3:156 ref:Saunder, Genomics 1990; 8:525 PNAS 1989; 86:8813 Differentiation 1989; 40:99 Nucl Acid Res 1987; 15:3622 Nature 1985; 314:542 PNAS 1985; 82:2920 ref:Miller, Immunogenetics 1989; 30:511 ref:Letourneur, Immunogenetics 1989; 29:265 ref:Hearne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 Nature 1986; 321:431 PNAS 1987; 84:1664 ref:Letourne~r, Immunogenetics 1989; 29:265 PNAS 1987; 84:7649 ref:Tunnacliffe, Nucl Acid Rea 1989; 17:4418 tel:Miller, Immunogenetics 1989; 30:511 J Biol Chem 1988; 17:8528 PNAS 1988; 85:8623 ref:Krissansen, J Immunol 1987; 138:3513 ref:Krissansen, Immunogenetics 1987; 26:258 ref: Kingsley, Genetics 1989; 123:165 ref:LetournetLr, Immunogenetics 1989; 29:265 ref:Letourneur, Immunogenetics 1989; 29:265 EMBO J 1986; 5:1799 J Immunol 1987; 138:3513 J Exp Meal 1987; 166:1186 Continued on next p a g e

J.T. Eppig: Clones and Probes

359

Table 3. Continued. Chr Syml~a

9

Thy-1

Locus Name

thymus cell antigen-1

Probeb

TM8

RFLVc Contactd

Davis Hedrick co:M Davis + co:Huppi + co:S Hodrick [R] pT64 Moriuchi Evans [R] pT64, pT86 Seki pcD-29-5A Hiraki Probe A, Probe B, Probe C co:F Grosveld pT2 Giguere MMTHY1G (microsat) + co:JA Todd Thy-1, 3' untranslated Thy-lE (=Probe D) co:F Grosveld Thy-lI co:F Grosveld Thy-1, third intron (allele 1.1) Thy-1 genomic Giguere (allele 1.2) PST108, CT10, CT34, co:J Silver CTSF, pdI~34, Pv3 co:J Silver peT108 + ce:J Silver pBST1, pMT1 Giguere pTby-2.2 Chen pThy-2.2, Ch4A-Thy-IA Evans Ingraham 9 Tpi-4 triosephosphate isomerase related seq-4 [H] pHTPI-SA Maquat + co:LE Maquat [R] pRtfl7 Baranov 9 Trf transferrin pMTF-5 Chen + eo:Chen Trf probe + Friedman 9 Ups uroporphyrinogen I synthetase co~-Pbgd-M Beaumont pMo-MCFI-16 + co:Vogt xenotropic-MCF leukemia virus-2 9 Xmmv-2 9 Xmmv-67 xenotropic-MCF leukemia virus-67 pXenv + co:MA Martin xenotropic murine leukemia virus-15 JS-6flS-10 + Frankel 9 Xmv-15 JS-6+JS-10, XENOll2 + Frankel Xmv-16 xenotropic murine leukemia virus-16 JS-6flS-10 + Frankel 9 Xmv-25 xenotropic murine leukemia virus-25 JS-6flS-10 + Frankel 9 [C] ~2000 Cleveland actin related gene-2 10 Act-2 + co:SH Hughes (NCI) 10 Ahi-1 Abelson helper integration site Ahi-1 genomic Peirier probes A, B, C, D, E Poirier p2-1 Poirier + co:P Jolicouer [R] pRMIS1 + co:RL Cate, Biogen 1O A m h anti-Mullerian hormone pMIS330.5-2 + King 10 Ass-ps2 arginosuccinate synthetase, pseudo-2 [H] pAS-1 co:A Beaudet BCR eDNA + co:A DeKiein (NCI) 10 Bcr breakpoint cluster region homolog 2-21 + co:N Heisterkamp [H] probe 1 Heisterkamp + co:N Heisterkamp [H] pEX Ikawa 1O Braf Braf transforming gene + co:T Yamamoto 10 Bsg basigin pFR27, pFR1 co:T M u r a m a t s u co:T M u r a m a t s u 10 Cdl8 CD18 antigen [=Mac-1 ~ subunit] clone 17.4 Wilson [H] Cdl8 eDNA MacDonald [H]Mp-18 + co:T Kishimoto 1O Cdc2a cell division cycle 2 homolog, Chr 10 C1-BS Cisek + co:JL Corden CDCMm Spurt Th'ng 10 Col6a-1 procollagen type VI (al) [H] p18 Well + co:M-L Chu [H] Col6a-1 eDNA + MacDonald 10 Col6a-2 procollagen type VI (a2) [H] pl Chu + co:M-L C h u [H] Co16a-2 e D N A + MacDonald Col6a-2 c D N A - P C R Constantinou DNA segment, Chr 10, Costantini-1 1~2351 + co:F Costantini 10 D10Cosl 1O D10Ledl DNA segment, Chr 10, P Leder-1 D10Ledl + Beier 1O Dl0Led2 DNA segment, Chr 10, P Leder-2 D 10Led2 + Beier 10 D10Led3 DNA segment, Chr 10, P Leder-3 D10Led3 + Beier 10 DlOPasl DNA segment, Chr 10, Pasteur Institute-1 123N + co:L Amar DNA segment, Chr 10, Pasteur Institute-2 123A + co:L Amar 1O D10Pas2 1O D12S53Eh DNA segment, Chr 10, humanD12S53E Pme117-1 + Kwon downless (TgOVE 1) gr4, grl5, grl9, grl8, probe A Shawlot 1O dl probe A + Shawlot downless (wildtype, BALB/c) Wt 18,Wt33 .Wt38,Wt 14,Wt3 7 Shawlot

Referencee

Nature 1983; 301:80

Nature 1964; 308:149 ref:Hiraki, J Immunol 1986; 136:4291 ref: Kingsley, Genetics 1989; 123:165 ref:Miller, Immunogenetics 1989; 30:511 Nature 1983; 301:80 PNAS 1984; 81:5532 Science 1985; 227:649 J Immtmol 1986; 136:4291 refiSpanopoulou, Mel Cell Biiol 1988; 8:3847 F_aMBOJ 1965; 4:2017 ref:Aitman, M a m m Genome 1991; 1:206 ref:Spanepoulou, Mel Cell Biol 1988; 8:3847 ref:Spanopouloth Mol Cell Biol 1988; 8:3847 EMBO J 1985; 4"2017 ref:Chang, PNAS 1985; 82:3819 ref:Chang, FNAS 1985; 82:3819 refiD'Eustachio, PNAS 1985; 82:7631 EMBOJ 1985; 4:2017 Cell 1987; 51:7 PNAS 1984; 81:5532 Mol Cell Biol 1986; 6:2923 J Biol Chem 1985; 260:3748 ref.'Siracusa, Genetics 1991; 127:169 Chromosoma 1987; 98:60 J Biol Chem 1987; 262:17247 ref: Kingsley, Genetics 1989; 123:165 Genomics 1989; 5:463 J Biel Chem 1989; 264:14829 ref: Blatt, PNAS 1983; 80:6298 ref:Wejman, J Virol 1984; 50:237 J Virol 1989; 63:1763 M a m m Genome 1992; 2:110 J Virol 1989; 63:1763 J Virol 1989; 63:1763 Cell 1980; 20.05 refiJustice, Genetics 1990; 125:855 J Virol 1988; 62:3985 J Virol 1988; 62:3985 J Virol 1988; 62:3985 ref.'Jtmtice, Genetics 1990; 125:855 ref:King, Genornics 1991; 11:273 Genomics 1991; 11:273 ref:Nakamura, Cytogen Cell Gen 1985; 40:710 ref.'Justice, Genetics 1990; 125:855 ref.'Justice, Genetics 1990; 125:855 N u d Acid Res 1988; 21:10069 refJustice, Genetics 1990; 125:855 Mol Cell Biol 1988; 8:2651 ref:Jtmtice, Genetics 1990; 125:855 ref:Miyauchi, J Biochem 1990; 107:316 ref:Kanekura, Cell Struct Funct 1991; 16:23 Nucl Acid Res 1989; 17:5397 Am J Hum Genet 1988; 43:A151 (abst) ref:MacDonald, Genomics 1991; 11:317 Nature 1989;, 339:679 ref.'Justice, Genetics 1990; 125:855 Sequence 1990 (in press) Cell 1990; 63:313 A m J Hum Genet 1988; 42:435 ret~Justice, Genetics 1990; 125:855 Genomics 1991; 11:317 E u r J Biochem 1987; 168:309 relSJustice, Genetics 1980; 125:855 Genomics 1991; 11:317 Matrix 1991; 11:1 rei~Iustlce, Genetics 1990; 125:855 Genomics 1991; 10:1003 Genomics 1981; 10:1003 Genomics 1991; 10:1003 ref:Buckle, H u m Genet 1990; 85:324 ref:Buckle, H u m Genet 1990; 85:324 PNAS 1991; 88:9228 Mol Biol Meal 1989; 6:299 Mol Biol Meal 1989; 6:299 Mol Biol Meal 1989; 6:299 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

360 Table 3. Continued. (7or Symbola

10 10

Dmdl

10

Emv-25

10

Estr

10 10

Fispl2 Fyn

10

Gad-lps

10

Gja-1

10

Gli

10 10

Hal Hb58

10

Ifg

Egr-2

10 Ifgr

10

I~-1

10

Mdm-i

10 10

Mdm-2 Mgf

10 10

Mip "Mns-10"

10 Mpmv-5 10 Mpmv-12 10 Myb

Lores Name

Probeb

RFLVc Contactd

%wt#38 (=Wt38) pBfm3 dystrophin-like early growth response-2 (=Zfp-25, Krox-20) AC16, pEX2.8 ACI6 phage 22 8/4, 13/13, 16/13, pG122 endogenous ecotropic MuLV-25 pEco pEc-B4, pEc-env pEc-env pEco, pEc-B4 estrogen receptor [H] pOR3

Referencee

co:P Overbeek refiBoyle, Genomics 1992; 12:106 H u m Genet 1990; 85:324 Buckle EMBO J 1988; 7:29 Chavrier PNAS 1988; 85:4691 Lemaire Chavrier Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1989; 9:787 Chavrier Chattopadhyay PNAS 1980; 77:5774 Chan PNAS 1980; 77:5579 + Kozak Genomics 1990; 8:519 + Taylor Genomics 1989; 5:221 Green Nature 1986; [email protected] rofiJtmtice, Genetics 1990; 125:855 + co:ATTC fibroblast inducible secreted protein 12 kF27 co:R Brave ref:Ryaeck, Cell Growth Differ 1991; 2:225 Fyn proto-oncogene [H] Fyn eDNA Kawakami Mol Cell Biol 1986; 6:4195 " + co:K Robbins (NIH) rof:Justice, Genetics 1990; 125:855 pSN-2 Semba PNAS 1988; 63..5459 Katagiri PNAS 1989; 86:10064 clone 109 Dymecki Science 1990; 247:332 glutamie acid decarboxylase-1 pseudo [F] sp65-GAD-16 co:D K a u f m a n Brilliant, Genomics 1990; 6:115 MGAD8A, MGAD33A Brilliant Genomics 1990; 6:115 clone 1A1 + co:Z Katarova ref:Brilliant, Genomics 1990; 6:115 gap junction membrane channel protein a l [R] a l GJ Hsieh Sore Cell Mol Genet 1991; 17:191 (connexin 43) ATPR genomic, J774 genomie co:TH Steinberg ref:Beyer, J Biol Chem 1991; 266:7971 [B] GJ3 Lash J Biol Chem 1990; 265:13113 h u m a n glioma associated oncogene pMGLI-RS + co:B Vogelstein rsfiJustice, Genetics 1990; 125:855 + co:M Ruppert ref:Kozak, Genomics 1990; 8:519 histidine ammonia lyase (histidase) [R] pHAL, [H] HAL-hl co:RR McInnes ref:Taylor, Cytogenet Cell Genet 1991; 56:178 flank of transgene insertion (HU ~ globin) ),13, probe E Radice Development 1991; 111:801 probe B, D + Radice Development 1991; 111:801 interferon y Ifg eDNA Gray PNAS 1983; 80:5842 Naylor Somatic Cell Mol Genet 1984; 10:531 MTIFN + co:H Young, D-I Arai ref:Justice, Genetics 1990; 125:855 pMifkol + co:A Billiau rofiKozak, Genomics 1990; 8:519 interferon ~/receptor kMuI FN-TR4,)`M uI FN-TR7 Kumar J Biol Chem 1989; 264:17939 kM uI FN-TRS,pMuI FN-TR36 K u m a r J Biol Chem 1989; 264:17939 pMuIFN-TR36 + Kozak Genomics 1990; 8:519 Ifgr eDNA Gray PNAS 1989; 86:8497 kMG7 Munro PNAS 1989; 86:9248 kMIR3bl Cofano J Biol Chem 1990; 265:4064 insulin-like growth factor-1 migfl- 1, migi'1-2 Bell Nucl Acid Res 1986; 14:7873 migfl-3, migfl-9 Bell Nucl Acid Res 1986; 14:7873 migfl-4, migfl- 13 Bell Nucl Acid Res 1986; 14:7873 migfl-10, migfl-13 Bell Nucl Acid Res 1986; 14:7873 PCR-Igf-1 Telford Mol Reprod Devel 1990; 27:81 pmigfl-2 + co:G Bell ref:Justice, Genetics 1990; 125:855 [ R ] P2 testis IGF-1 + co:PK Lund,SJ Casella rof:Taylor, Cytogenet Cell Genet 1991; 56:57 transformed mouse 3T3 cell double minute-1 kcl01,kcl02, p12 Cahilly-Snyder Somatic Cell Mol Genet 1987; 13:235 kcl01,kcl02,Mdm-1 genomic Snyder J Biol Chem 1988; 263:17150 kcl03,kc 104,kc105,p12 Snyder J Biol Chem 1988; 263:17150 transformed mouse 3T3 cell double minute-2 kc201,kc202, pdm66 Snyder J Biol Chem 1988; 263:17150 mast cell growth factor pMGF-4 Copeland Cell 1990; 63:175 + co:S Lyman rof:King, Genomics 1991; 11:273 MGF.4, Mgf genomic + co:NG Copeland rof:Brannan, PNAS 1991; 88:4671 Mgf-Sl d eDNA co:NG Copeland ref:Brannan, PNAS 1991; 88:4671 pBSSK-MGF-4 + Copeland Cell 1990; 63:175 KL eDNA + Huang Cell 1990; 63:225 SCF eDNA + Zsebo Cell 1990; 63:213 MGF-2, MGF-94, Anderson Cell 1990; 63:235 MGF-4,MGF-10 Anderson Cell 1990; 63:235 major intrinsic protein of lens fiber MIP eDNA Griffin Cytogenet Cell Genet 1992; 59:300 minor satellite Chr 10 (centromeric) pMR150 Voliva Nucl Acid Res 1983; 11:8847 co:VM C h a p m a n ref:Broccofi, Cytogenet Cell Genet 1990; 54:182 co:ND Hastie ref:Pietras, Nucl Acid Res 1983; 11:6965 modified polytropic murine leukemia virus-5 JS-4 Frankel Genetics 1990; 124:221 modified polytropic murine leukemia virus-12 JS-4 Frankel Genetics 1990; 124:221 JH co:W Frankel ref:Gerstein, Cell 1990; 63:537 JS-4, MCF100 Frankel M a m m Genome 1992; 2:110 myeloblastosis oncogene F8 co:R Gallo ref:King, J Immunol 1990; 144:3218 ~_.tM2b co:Mock, Huppi ref:Mock, Nucl Acid Res 1987; 15:4700 Kozak Genomics 1990; 8:519 co:Lavu ref:Moen, Manana Genome 1991; 1:217 P-myb co:Oncor refiTrapani, J Exp Med 1990; 171:545 pmcl Knight Mol Cell P r o b ~ 1990; 4:497 pSP65-v-myb Collart J Immunol 1987; 139:949 [V] v-myb co:M Shibuya, T Yamaoto refiTodokoro, BBRC 1986; 135:1112 IV] pVM2 Klempnauer Cell 1982; 31:453 +

Continued on next p a g e

361

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Symbda

Loc~ Name

10

Myb

10

Pah

10

Pfkl

phosphofructokinase, liver

10

Pfp

pore-forming protein (lymphocyte)

10

pgcha

pygmy insertional mutation, Tg-pgl pygmy insertional mutation, Tg-pg2

10

Pmv-8

polytropic murine leukemia virus-8

10

Pmv-13

polytropic murine leukemia virus-13

10

Priml

DNA primase, p49 subunit

10 10

Rnu3b-ps4 U3B small nuclear RNA-3 pseudogene 4 Ros-1 proto-oncogene Ros - 1

10

S100b

S100 protein, ~ polypeptide (neural)

10 10

SI Tg.EB

i0

Tpi-5

steel (see Mgf) transgene EB insertion site (0.8 cM from S1) triosephosphate isomerase related seq-5

10

Tpi-6

~rio~ephosphato isomerase related seq-6

10

Tpi- 7

triasephosphate isomerase related seq-7

10

Tra- 1

tumor rejection antigen (gp96)

Xmv-31

xenotropic murine leukemia virtts-31

Xmv-51 Xmv-54 Zfa

xenotropic murine leukemia virus-51 xenotropic murine leukemia virus-54 zinc finger protein, autosomal

Acrb

acetylcholine receptor

Adra- 1

adrenergic receptor, a l

10 10 10

myeloblastosis oncogene

phenylalanine hydroxylase

Probeb

RFLW Contactd

Ref~aee e

Sakaguchi Lavu Lavu Shen-Ong Mucenski + co:Shen-Ong (NCI) + co:Shen-Ong (NCI) MM49 Gonda gt11-5, gtl0-10, Myb genomic Bender k~nybl, ~nyb2, MM49 Sobieszczuk MUSMYBM (microsat) + co'JA Todd [R] ~xPH1, [R] ~rPH2, co:Dahl, Mercer [R] pRPH1, [R] pRPH2 co:DahI, Mercer [R]PAH (pRPH1 or pRPH2) + Bode Pah-PCR + Justice moPAH8 Ledley Ledley + co:Woo & Ledley + co:JD McDonald + co:S Woo [H] Pfkl cDNA + eo:Y Groner ~.LPFK-1, ~.LPFK-2, co:HS Sul ~.LPFK-3, kLPFK-4 co:HS Sul PFP-6, PFP-15, PFP-9 Kwon PFP-6 + Kozak PFP-6 + Trapani :kPFP- 64,~.PFP-67,PFP- 15 T r a p a n i Tg-pg flank Xiang Xiang + co:K Chada + co:K Chada + co:K Chada JS-5 Frankel + Frankel JS-5 Frankel + Frankel pcmSP Prussak Adler pml~ P, prebe U Mazan [H] pSc3.2/23 Birchmeier + co:C Birchmeier [H] pHSl00f2.2 Allore + co:R Dunn (Toronto) [R] S100b cDNA + co:R Dunn [R] BPB MacDonald

PNAS 1984; 81:525 Nucl Acid Res 1986; 14:5309, Nucl Acid Res 1986; 14:5309 Science 1984; 226:1077 J Virol 1988; 62:639 ref.'Justice, C,enetics 1990; 125:855 ref.'Taylor, Genomics 1989; 5:221 EMBO J 1985; 4:2003 PNAS 1986; 63:3204 Nucl Acid Rcs 1989; 17:9593 ref:Hearne, M a m m Genome 1991; 1:273 J Biol Chem 1986; 261:4148 J Biol Chem 1986; 261:4148 Genetics 1988; 118:299 Genetics 1990; 125:855 Cytogenet Cell Genet 1988; 47:125 Biochem J 1990; 267:399 ref:McDonald, PNAS 1990; 87:1965 ref:King, Genomics 1991; 11:273 ref:Keller, PNAS 1990; 87:10019 res Genomics 1991; 11:317 ref.-Rongnoparut, J Biol Chem 1991; 266:8086 res J Biol Chem 1991; 266:8086 BBRC 1989;, 158:1 Genomics 1990; 8:519 J Exp Med 1990;, 171:545 J Exp MOd 1990, 171:545 Science 1990; 247:987 Science 1990; 247:967 ref.'Justice, Genetics 1990; 125:855 ref:King, Genomica 1991; 11:273 ref:Frankel, Mamra Genome 1992; 2:110 J Virel 1989; 63:3810 M a m m Genome 1992; 2:110 J Virol 1989; 63:3810 M a m m Genome 1992; 2:110 J Biol Chem 1989; 264:4957 Genomics 1991; 9:642 Cytogenet Cell Genet 1991; 56:18 Mol Cell Biol 1986; 6:3109 ref'Hustice, Genetics 1990; 125:855 Science 1988; 239:1311 ref'Hustice, Genetics 1990; 125:855 tel:MacDonald, Genomics 1991; 11:317 Am J Hum Genet 1988; 43:A151 (abst)

TIS Dra/Sal (=D10Led3) + H u a n g EB34 + Beier [H] pHTPI-5A Maqtmt + co:LE Maquat [H] pHTPI-5A Maquat + co:LE Maquat [H] pHTPI-SA Maquat + co:LE Maquat pC5-19, pMA2, Srivastava kMA53, ;(NIA72 Srivastava pMA2 Srivastava + Kozak JS~+JS-10 Frankel JS-6+JS-10, XENOll2 + Frankel JS-6+JS-10, XENOll2 + Frankel JS-6+JS-10, XENOll2 + Frankel mYfin + Nagamine pDP1068 Page [I-I] pCMPXY1 + Mitchell + co:C Bishop pDPl194 Mardon ~ l~obe + co:Heidmann ]37, ~22 Buonanno ~ 9 7 , kg1581,kg~82, Buonanno kg~l l l , kg~l Buonanno MUSACHRBB (microsat) + co:JA Todd (microsat) + co'JATedd [CH] a l - A R genomic Cotecchia Yang-Feng [CH] Adra-1 cDNA + co:RJ Lefkowitz

Cell 1990; 63:225 Genomics 1991; 10:1003 J Biol Chem 1985; 260:3748 ref:Siracusa, Genetics 1991; 127:169 J Biol Chem 1985; 2~.3748 ref:Siracusa, Genetics 1991; 127:169 J Biol Chem 1985; 260.3748 ref.'Siracusa, Genetics 1991; 127:169 PNAS 1987; 84:3807 PNAS 1987; 84:3807 Immunogenetics 1988; 28"205 Genomics 1990; 8:519 J Virol 1989; 63:1763 M a m m Genome 1992; 2:110 Mamm Genome 1992; 2:110 M a m m Genome 1992; 2:110 Science 1989; 243:80 Genomics 1990; 7:37 Genetics 1989; 121:803 ref:King, Genomica 1991; 11:273 Mol Cell Biol 1990; 10:681 Science 1986; 234:866 J Biol Chem 1986; 261:16451 J Biol Chem 1989; 264:7611 J Biol Chem 1989; 264:7611 ref:Hearne, M a m m Genome 199:1; 1:273 ref:Montagutelli, M a m m Oenome 1991; 1:255 PNAS 1988; 85:7159 PNAS 1990; 87:1516 ref:Buckwalter, aenomics 1991; 10:515

[V] KX1 k~*IM1, ~.gt34-1 Myb genomic

Continued on next page

J.T. Eppig: Clones and Probes

362 Table 3. Continued. or Sym~a

Locus N a m e

11 11

Akv-4 Asgr-1

(withdrawn, = Emv-14) asialoglyeoprotein receptor-1

11 11

Asgr-2 Atplb2

asialoglycoprotein receptor-2 ATPase, Na+, K+, [32 polypeptide

lhd~b

[R] RHL4 Asgr-1 eDNA [R] RHL-2/-3eDNA [R] Atpb-2 eDNA AMOG eDNA Gb-2, Gb-5, Gb-9a Atplb2 microsat

11

Cabin

11

Ck-5

calcium binding membrane associated protein (p68) creatine kinase-5

1/

Cnp-1

cyclic nucleotide phosphodiesterase-1

11

Cola-1

procollagen type I, a l

11

11

11 11 11 11 11 11 11 11 11 11 11

11 11

CF4.2

RFLV ~ Coata~d

+ + + +

co: K Driekamer co:J Sanford Sanford Malo Pagliusi + Hsieh co:R Levenson M agyar + co:Magyar Davies

[H] pCPK-B [R] pCNP-2 clone 071, clone 201 p13, p13-3 p13-3 Mov-13 genomic- 1 Mov-13 genomic-2 Mov-13 genomic-3 pI p13

+ +

+

+ MMCOLA13 (mierosat) + [H] pglH-1 pMCollal-1 (pEVEH0.4) [H] Hf677 Yac Y22, Yac Lt ;~IC,C-3,-5,-10,-11 pMGCBG pMG2 " + pBRG-4 + pGM'~17 Csfgm eDNA

Mariman eo:ECM M a r i m a n Bernier Mon0h Harhers co:R Jaenisch Jaenisch Jaenisch Jaenisch co:Harbers Munke Schnieke co:JA Todd co:D Rowe co:E Vuorio Chu

co:R Jaenisch co:S Nagata eo:S Nagata Ts uchiya co:NG Copeland eo:Tsuchiya Csfgm colony stimulating factor, granulocyte Barlow macrophage specific co:Arai(DNAX) lhle ;~GM-CSF12, p~.GM-CSF12 Miyatake pEl-ll Miyatake " + co:NG Copeland + Buehberg pGM37, pGM38 Gough Gough pGM3.2, pGM5'd17 Gough pGM eDNA fragment + co:W Paul pGHS'19 + co:S Gisselbrecht pGM3.2 Gough ~.GM-1, kGM-4, pSVGM-5 Stanley ).8.2 Ymer k8.2, GM-CSF eDNA, P1 Lee 3 MMGMCSFG (microsat) + co:JA Todd (micrasat)+ co:JA Todd + co:JA Todd D4S10h DNA segment, Chr 11, h u m a n D4S10 [H] G8, [I-I] pK082 Cheng [H] pSCa3 + Cheng "DllH38" DNA segment, Chr 11, H38 eosmid H38 Boyle " D l l H a m l " DNA segment, Chr 11, Hamburg-1 p15-4 Harbers DllJknl DNA segment, Chr 11, Jackson-1 ~.-TYR-0.8 + Jackson DllLehl DNA segment, Chr 11, Lehrach-1 B2 SINE (GACA) 3 + Cox DllLeh2 DNA segment, Chr 11, Lehrach-2 B2 SINE (GACA)3 + Cox "DllMcCI" DNA segment, Chr 11, McClelland-1 AP-PCR oligo KA + eo:M McClelland DllNds2 DNA segment, Chr 11, Nuffield Dept Surg-2 MMU2SNR(microsat) + co:JA Todd (microsat) + co:JA Todd DllWas7O DNA segment, Chr 11, Univ of Wash-70 prvbe 70-38 Disteche Disteche Edp-1 endothelial cell derived protein Edp-1 probe + eo:V Dixit Epba erythrvcyte membrane protein band 3 Empb3-PCR + Love MMBAND3I (microsat) + co:JA Todd " (rrdcrosat) + eo:JA Todd MMAEPR (microsat) + co:JA Todd Emv-14 endogenous ecotropic MuLV-14 pEca Chattepadhyay pEc-B4 Chart pEco, pEt-B4 + Taylor Emv-28 endogenous ecotropic MuLV-28 pEco Chattopadhyay pEc-B4 Chart pEco, pEc-B4 + Taylor Csfg

colony stimulating factor, granulocyte

l%efa~acee

ref:Sanford, DNA 1988; 7:721 ref:Buekwalter, Genomics 1991; 10:515 DNA 1988; 7:721 Genomics 1990; 6:697 J Neum8~ Res 1989; 22:113 Somatic Cell Mol Genet 1990; 16:401 ref:Shyjan, Genomics 1991; 11:435 Nuel Acid Res 1991; 18:6695 ref:Hearne, M a m m Genome 1991; 1:273 H u m Genet 1989; 82:234 Genomics 1987; 1:126 ref:Cho, M a m m C-enome 1991; 1:30 J Neumsci Pea 1988; 20:497 BBRC 1989;, 165:1213 PNAS 1984; 81:1504 ref:Jahner, Mol Col Biol 1985; 5:2212 Cell 1983; 32:209 Cell 1983; 32".209 Cell 1983; 32:209 ref:Buchberg, Genetics 1989; 122:153 Cytogenet Cell Genet 1986; 4,3:140 Nature 1983; 304:315 refiAitman, M a m m Genome 1991; 1:206 ref:Schnieke, Nature 1983; 304:315 ref:Metsaranta, BBA 1991; 1089:241 Nucl Acid Res 1982; 10:5925 refiStrauss, EMBO J 1992; 11:417 ref:Tsuchiya, Eur J Biochem 1987; 165:7 ref:Tsuchiya, Eur J Biochem 1987; 165:7 PNAS 1986; 83:7633 ref:Buehberg, Oneogene Res 1988; 2:149 ref:Buehberg, Genetics 1989; 122:153 EMBOJ 1987; 6:617 ref: Cough, Nature 1984; 309:763 J Immunol 1987; 138:3051 EMBO J 1985; 4:2561 EMBO J 1985; 4:2~61 ref.'Buchberg, Oncogene Res 1988; 2:149 Genetics 1989; 122:153 Nature 1984; 309:763 EMBO J 1985; 4:645 EMBO J 1985; 4:645 ref:Buckwalter, Genomics 1991; 10:515 ref.'Sola, J Virol 1988; 62:3973 EMBO J 1985; 4:645 EMBO J 1985; 4'2569 Nature 1985; 317:255 Genomics 1989; 5:359 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 ref:Baldacci, M a m m Genome 1992; 2:100 DNA 1987; 6:401 DNA 1987; 6:401 Genomics 1992; 12:106 Cytogenet Cell Genet 1990;, 53:129 Mouse Conome 1990; 86:226 Genomics 1991; 10:375 Genomics 1991; 10:375 tel:Welsh, Nucl Acid Res 1991; 19:5275 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; h255 Cytometry 1990; 11:119 Cytogenet Cell Genet 1985; 39:262 ref:Buckwalter, Genomics 1991; 10:515 N u d Acid Res 1990; 18:4123 ref:Hearne, Mamin Genome 1991; h 273 ref:Montagutelli, M a m m Genome 1991; 1:255 ref:Hearne, Mamma Genome 1991; h 273 PNAS 1980; 77:5774 PNAS 1980; 77:5579 Genomics 1989; 5:221 PNAS 1980; 77:5774 PNAS 1980; 77:5579 Genomics 1989; 5:221 Continued on next page

J.T. Eppig: Clones and Probes

363

Table 3. Continued. Chr Symbda

11 ll

Emv-30 Erba

11

Erbb

11

Erbb-2

11

Evi-2

11 11 11

Gaa Gabra-1 Gas-3

11

Gfap

11

Gh

11

Glns

11

Glut-4

11

Hba

11 11 11

Hba-x Hmgi-rsl Hox-2

I~cus Name

endogenous ecotropic MuLV-30 avian erythroblastosis oncogene A

Probe b

Emv-env probe v-ErbA (Oncor)

RFLVc O m t ~ d

+ + + +

Prochazka co:Oncor co:Oncor co:Oncor clone 29, clone 32 co:LA Gavin IV] pAEPst co:JM Bishop pE2A3D co:TJ Robinson [R] Erba eDNA Lazar " + co:R Koenig avian erythroblastosis oncogene B v-ErbB (Oncor) + co:Oncor " + co:Oncor + co:Oncor + co:Oncor " + co:Yu [V] pAEBamRI co:JM Bishop [H] Erbb genomic Jansson " + eo:B Vennstrom + Ihle [H] HER64-3 Ullrich co:A Ullrich (=pliER-A64-1) + Kaupmann [C] Erbb cDNA + co:ATCC avian erythroblastosis oncogene B-2 neuc(t)/sp6400 Bargmann + co:Barbacid + co:Bargmann neu(t)34 Bargmann ecotropic viral integration site-2 p597.1 + 1-Copeland + Buchberg pXS1.9 Buchberg + Eicher + Elliott RI-G, p597.1 Buchberg pBK3.3, pXS1.9 Buchberg a d d a glucosidase [H] pUC18xGAA + Martiniuk GABA-A receptor, s u n u n i t a-1 GABA a l eDNA + Keir growth arrest specific-3 Gas-3 eDNA- 1 Schneider Gas-3 eDNA-2 + co:P D'Eustachio glial fibrillary acidic protein pG18, pG13 Balcarek clone G1 Lewis pGFAP-G1 (=clone G1) + Bernier MMGFAPD (microsat) + co:JA Todd MMGFAPD (microsat) + co:JA Todd growth hormone piT148 Linzer co:DIH Linzer [R] pRGH Seeburg + Eicher + Elliott + Winklemann [13] Gh genomic Woychik + co:F Rottman Gh PCR + Buckwalter glutamine synthetase SE1,9, Glns-genomic Bhandari [R] pGSRK-1 Burns MMGLN1 (microsat) + co:JA Todd (microsat) + co:JA Todd glucose transporter-4, muscle, fat GT2 eDNA Kaestner ~.GLUT4 genomic Kaestner Glut4 microsat § co:Kaestner [R] Glut-4 eDNA Charron Glut-4 PCR (from Glut-4cDNA) + co:A Schultz hemoglobin a chain complex unnamed Nishioka pCRlaMG10, pCRlaMG4 Rougeon pCRlaMG4 + co:F Rougeon phage 1, phage 3, phage 6 Leder a-adl + co:P Leder a-(p3 + Eicher psia30.5 + Elliott mur.a-1 globin co:P Leder (from C57BIJ10) C57a10, C57a13 Erhart (from SWR/J) SWRal04, SWRal08 Erhart (from CE/J) CEaS, CEa8 Erhart hemoglobin-X (a-like embryonic chain) phage 1, phage 2 Leder high mobility group protein I related seq-1 HGMI cDNA + Johnson homeo box-2 cluster pMo4-6, pMol-1, kMo-3 Hart MMHOX23R (micrcsat) + co:JA Todd (micrcsat) + co'2A Todd

Referencee

Mouse C,enome 1991; 89:258 ref:Buchberg, Oncogene Re~ 1988; 2:149 rei~Buchberg, Genetics 1989; 122:153 ref:Elliott, Genomics 1990; 8:591 ref:Moeller, J Neuroendocrin 1989; 1:351 ret~Zabel, PNAS 1984; 81:4874 refiMorris, M a m m Genome 1991; 1:263 Mol Endocrinol 1988; 2:893 ref:Buckwalter, Genomics 1991; 10:515 ref:Buchharg, Oncogene Res 1988; 2:149 refiBuchberg, Genetics 1989; 122:153 ref:Eicher, Genetics 1990; 125:431 ref:Elliott, Genomics 1990; 8:591 ref:Moen, M a m m Genome 1991; 1:217 re~Zabel, PNAS 1984; 81:4874 EMBO J 1983; 2:561 tel:Silver, Mol Cell Biol 1985; 5:1784 J Immunol 1987; 138:3051 Nature 1984; 309:418 ref.'Munke, J Mol Evol 1987; 25:134 Genomies 1992 (in press) ref:Buckwalter, Genomics 1991; 10:515 Nature 1986; 319:226 ref:Buchberg, Oncogene Res 1988; 2:149 refiBuchberg, Genetics 1989; 122:153 Nature 1986; 31~.226 ref:Buchberg, Oncogene Res 1988; 2:149 Genetics 1989; 122:153 Oncogene Res 1988; 2:149 Genetics 1990; 125:431 Genomics 1990; 8:591 Mol Cell Biol 1990; Mol Cell Biol 1990; 10:4858 M a m m Genome 1991; 1:267 Genomics 1991; 9:390 Cell 1988; 54:787 tel:Colombo, M a m m Genome 1992; 2:130 Nucl Acid Res 1985; 13:5527 PNAS 1984; 81:2743 J Neuresci Res 1988; 20:497 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 J Biol Chem 1985; 260:9574 ref:Jackson-Grusby, Endocrin 1988; 122:2462 Nature 1977; 27~486 Genetics 1990; 125:431 Genomics 1990; 8:591 Genome 1990; 33:235 Nucl Acid Res 1982; 10:7197 ref:Buckwalter, Genomics 1991; 10:515 Genomies 1991; 10:515 PNAS 1988; 85:5789 BBRC 1986; 134:146 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 PNAS 1989; 86:4937 PNAS 1990; 87:251 ref:Hearne, M a m m Genome 1991; 1:273 PNAS 1989; 86:2535 ref:Hogan, Development 1991; 113:363 Cell 1979; 18:875 Gene 1977; 1:229 ref:Robert, Nature 1985; 314:181 Nature 1981; 293:198 ref:Kaupmann, Genomics 1992 (in press) Genetics 1990; 125:431 Genomics 1990; 8:591 ref:Morris, M a m m Genome 1991; 1:263 Genetics 1987; 115:511 Genetics 1987; 115:511 Genetics 1987; 115:511 Nature 1981; 293:198 Genomies 1992; 12:503 Genomics 1987; 1:182 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 C o n t i n u e d on next p a g e

J.T. Eppig: Clones a n d Probes

364 Table 3.

Continued.

Chr Syrdmla

11

Hox-2.1

Loo~ Name

homeo box-2 duster, gene 1

Probeb

RFLVc C c a t a ~

kMo-4, pMo4-1, probe d2 probes d3, el, e2, f, g )~r pMul + H24.1 H24.1, pM1, pM5 pRRF5

RRF12 kd26 l~obe I, probe2 c2.1A, c2.1B, c2.1C pMu-lgSR, pMu-lcR3'

+ + +

+ Hox-2.1 cDNA Hox-2.1 probe + ccsmids l~osH15, peosH9 12

11

Hox-2.2

Hox-2.3

homeo box 2 duster, gene 2

homeo box-2 cluster, gene 3

YNot-Hox2 pMo4-6 pMo4-6, %Me-l, ~ 0 - 4 probes c, dl, d2, d3 Ch22 1:6 c5 cosmid pcosH15 YNot-Hox2 WF-10, WF-14 p611 kMo-1, k~io-3, pMol-1 probe c pMol-1

+

+

+ +

Ch22 p4, p5 (from Ch22) + L13,L2,L23, pR1.2, pR0.8 L13,L2, LR23, LR12, pR1.2 LRS, pR0.8 cosmids pcos5.4, pcosHl5 11

Hox-2.4

homeo box-2 duster, gene 4

11

Hox-2.5

homeo box-2 cluster, gene 5

12

Hox-2.6

borneo box-2 duster, gene 6

YNot-Hox2 MVIo-3, probe a k~r cosmid pcos5.4 YNot-Hox2 kW R 9 clone h14, kMo-21 cosmid pcosS.4 YNot-Hox2 Chl9 pl, p2(fromCh19) + kd24,kd21,kdl8,kd 16,kd 14 eDNA-2, eDNA-7 cosmids pcosH15, pcos3.1 cosmid pcosH9

11

Hox-2.7

homeo box-2 cluster, gene 7

YNot-Hox2 cosmid pcos.3.1

cosSD, YNot-Hox2 ~14,~t7,kd2,kd 10,%d11,kd3 H Hox-2.8 homeobox-2 duster, gene 8 co~D, YNot-Hox2 12 Hox-2.9 homeo box-2 duster, gene 9 cos8D 11 Hsp86-psl heat shock protein, 86kDa, pseudogene 1 dones 1, 2, 3,4 11 lap(Hox-2.4) intracisternal A particle, Hox-2.4 linked kWR20 11 Iap(I1-3) intracisternal A particle, Il-3 linked Iat~I1-3) genomic )oclones: 3.2, 3.4 ~clones: 3.5, 4.9

Hart Hart Hauser co:Joyner Jackson co:U Francke Joyner co:A Joyner Hauser Mock Mock Lonai Do Krumlauf Krumlauf Hauser Nadeau Watanabe Watanabe Graham Rubock Rubock Hart Hart Hart Lonai Lonai Schughart Graham Rubock Rubock Shen Singh Hart Hart Hart Nadeau Lonai Lonai Deschamps Meijlink co:A vandeKamp Graham Rubock Rubock Hart Bogarad Graham Rubock Rubock co:C Blatt Bogarad Graham Rubock Rubock Lonai Lonai Do Graham Graham Rubock Graham Rubock Rubock Graham Rubock Rubock Do Rubock Rubock Moore eo:C Blatt Ymer Ymer Ymer

Refe~mcee

Cell 1985; 43:9 Cell 1985; 43~ Cell 1985; 43:19 ref:Buchberg, Genetics 1989; 122:153 Nature 1985; 317:745 ref:Munke, Cytogenet Cell Genet 1986; 42:236 Nature 1985; 314:173 ref:Munke, Cytogenet Cell Genet 1986; 42:236 Cell 1985; 43:19 Genetics 1987; 116:607 N u d Acid Res 1987; 15:2397 DNA 1987; 6:409 Genomics 1988; 3:195 Development 1987; 99:603 Development 1987; 99:603 Cell 1985; 43:19 Genomics 1989; 5:454 Biochem Genet 1988; 26:805 Bicchem Genet 1988; 26:805 Genes & Devel 1988; 2:1424 PNAS 1990; 87:4751 PNAS 1990; 87:4751 Genetics 1988; 118:319 Cell 1985; 43:9 Cell 1985; 43:9 DNA 1987; 6:409 DNA 1987; 6:409 PNAS 1988; 85:558"2 Genes & Devel 1988; 2:1424 PNAS 1990; 87:4751 PNAS 1990; 87:4751 Nucl Acid Res 1991; 19:539 PNAS 1991; 88:10706 Cell 1985; 43:9 Cell 1985; 43:9 Genetics 1988; 118:319 Genomics 1989; 5:454 DNA 1987; 6:409 DNA 1987; 6:409 Differentiation 1987; 35:21 Nucl Acid Res 1987; 15:6773 ref:Meijlink, Nucl Acid Res 1987; 15:6773 Genes & Devel 1988; 2:1424 PNAS 1990; 87:4751 PNAS 1990; 87:4751 Cell 1985; 43:9 Develop Biol 1989; 133:537 Genes & Devel 1988; 2:1424 PNAS 1990; 87:4751 PNAS 1990; 87:4751 ref:Aberdam, Mol Cell Biol 1991; 11:554 Develop Biol 1989; 133:537 Genes & Devel 1988; 2:1424 PNAS 1990; 87:4751 PNAS 1990; 87:4751 DNA 1987; 6:409 DNA 1987; 6:409 Genomics 1988; 3:195 Genes & Devel 1988; 2:1424 Genes & Devel 1988; 2:1424 PNAS 1990; 87:4751 Genes & Devel 1988; 2:1424 PNAS 1990; 87:4751 PNAS 1990; 87:4751 Genes & Devel 1988; 2:1424 PNAS 1990; 87:4751 PNAS 1990; 87:4751 Genomica 1988; 3:195 PNAS 1990; 87:4751 PNAS 1990; 87:4751 J Biol Chem 1989; 264:5343 ref:Aberdam, Mol Cell Biol 1991; 11:554 Nucl Acid Res 1986; 14:5901 Nature 1985; 317:255 Nature 1985; 317:255 C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

365

Table 3. Continued. Chr Symbola

11

I1-3

Locus Name

interleukin-3

Probeb

RFLVc C o n t ~

plL3

pMu2A1 fpGV-IL12

+ + + + + + + +

pILM-3, pILM1 plLM3 pILM11, I1-3 genomic pILM21

11 11

II-3/Csfgm intergenic probe between Il-3/Csfgrn II-4 interleukin-4

" plLM21 derivative, P1, %8.2 L4.1, k4.10, L4.8, ~3.3 k 3.4, L3.5, ;~3.2 Iap(I1-3) genomic Il-3 cDNA kMGM3-2, ~.MGM5-6, LMGM9-7, XMGM12-4, pkMGM12-4 5(3, B4, BS, B6,138, B9 pSPMoII~ + MMIL3G (rnicrosat) + (mJcrosat) + probe P1 un na reed clone2AE3 LMIL9-3, kMIL16-1 pMIL1, pMII~5 pCB1 " + pSP6KmIL4-293 pSP6KmIIA-374 "

11

11-5

interleukin-5

11

Int-4

m a m m a r y tumor integration site-4

11

Krt-1

keratin complex-1

Krt-l.10

cytokeratin 18 keratin, Endo B-J31 keratin, Endo B-~2 keratin, Endo B-~3 keratin, Endo B-~5 keratin complex-i, gene 10

Krt-l.13

keratin complex-l, gene 13

+ +

+

I1-4 eDNA I1-4 genomie, probes A, B clone 4(] pSP6K-mTRF23 IL-5 eDNA/ + pEDFM-4, pEDFM-5 II-5-genomic 11-5 probe [HI IL-5 eDNA/I 152 MMILSG (microsat) + (microsat) + + pBG14 + + pK3.68(b2) + pK4.2 + pK435 + p3-68, p4-2 ZEB1, pEB1 danes 23,4,10,14 [HI pKB2 + pMHKll3-3.6R, gMHK113 pMHK113-4.4R pUC9B7 SK3112 EB31,EB25,EBpll EB1 EBp3 k59k-4 K10-2.6 + pKG59(4.0PstI) pKG59(6.0BamHI) pkt47 casK13-1, cosK13-2 pHH12, pSs2.8

Ihle Keir Joseph co:MC F u n g Pownall co:NM Googh eo:A Dunn, N Cough eo:NG Cope/and eo:Fung Fung eo:W Paul Campbell Campbell Campbell co:IG Young co:IG Young Lee Ymer Ymer Ymer Todokoro Miyatake Miyatake Miyatake Yokota Kaupmann eo:JA Todd co:JA Todd Lee Yokota Lee co:K Arai co:K Arai Brown D'Eustachio Noma Noma co:Y Noma eo:R Devos eo:R Deves Yokota Kinasbi co:S Clark Campbell Campbell eo:IG Young co:Azuma co:JA Todd co:JA Todd co:JA Todd co:Roelink Joseph Meruelo Meruelo Meruelo co:Compton co:A Matsushiro co:A Matsusbiro Fuchs Nadeau Kaytes Kaytes Singer Oshima Oshima Oshima Oshima Krieg Nadeau co:Compton eo:Compton Knapp Rentrop Winter Winter

Re/'e~e e

J Immunol 1987; 138:3051 Genomics 1991; 9:390 Cytogenet Cell Genet 1991; 56:122 refiColombo, M a m m Genome 1992; 2:130 Oenomics 1992; 12:699 refiBarlow, EMBO J 1987; 6:617 Brenmer, Cell 1990; 61:407 ref: Buchberg, Oncogene Res 1988; 2:149 refi Buehberg, Genetics 1989; 122:153 Nature 1984; 307:233 ref:Buckwalter, Genomics 1991; 10:515 E u r J Biochem 1985; 150:297 E u r J Biochem 1985; 150:297 Eur J Biochem 1988; 174:345 rei~Webb, Cytogenet Ceil Genet 1989; 50:107 ref:Marris, M a m m Genome 1991; 1:263 Genomics 1989; 5:359 Nature 1985; 317:255 Nature 1985; 317:255 Nucl Acid Ree 1986; 14:5901 BBRC 1966; 135:1112 PNAS 1985; 82:316 PNAS 1985; 82:316 PNAS 1985; 82:316 PNAS 1984; 81:1070 Genomics 1992 (in press) ref:Hearne, M a m m Genorne :1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 Genornics 1989; 5:359 PNAS 1986; 83:5894 PNAS 1986; 83:2061 reflOtsuka, Nucl Acid Res t987; 15:333 ref:Otauka, Nucl Acid Res 1987; 15:333 Cell 1987; 50:809 J Immuno11988; 141:3067 Nature 1986; 31~.640 Nature 1986; 319:640 ref:Takahashi, Genomics 1989; 4:47 ref:Kuhn, Science 1991; 254:707 refiKuhn, Science 1991; 254:707 PNAS 1987; 84:7388 Nature 1986; 324:70 refi Wilson, J Exp Med 1990; 171:1301 E u r J Biochem 1988; 174:345 E u r J Biochem 1988; 174:345 ref:Webb, Cytogenet Cell Genet 1989; 50:107 ref:Takahashi, Genomics 1989; 4:47 ref:Hearne, M a m m Genome 1991; 1:273 ref:MontaguteBi, M a m m Gent,me 1991; 1:255 ref:Baldacci, M a m m Genome 1992; 2:100 ref:Buehberg, Genetics 1989; 122:153 Cytogenet Cell Genet 1991; 56:122 Immunogenetics 1987; 25:361 Immunogenetics 1987; 25:361 Immtmogenetics 1987; 25:361 unpublished, Jackson Lab ref:Ichinese, Gene 1988; 70:85 ref:Iehinoso, Gene 1988; 70:85 Curr Top Dev Biol 1987; 22:5 Genomics 1989; 5:454 J Invest Devmatol 1991; 97:835 J Invest Dermatol 1991; 97:835 J Biol Chem 1986; 261:538 Genes & Devel 1988; 2:505 Genes & Devel 1988; 2:505 Genes & Devel 1988; 2:505 Genes & Devel 1988; 2:505 J Biol Chem 1985; 260:5867 Genomics 1989; 5:454 J Bid Chem 1985; 26~.5867 J Bid Chem 1985; 250:5867 Nucl Acid Res 1986; 14:751 d Ceil Biol 1986; 103:2583 Differentiation 1990; 4.3:105 Differentiation 1990; 43:105 Continued on next page

J.T. Eppig: Clones and Probes

366 Table 3. Continued. Chr Symbola

~lName

Krt-l.19

keratin complex-l, gene 19

11 11

"Krt-lps" Lif

keratin pseudogene leukemia inhibitory factor

11 11

Mgat- 1 Mipla

N-acetylglucosaminyltrans ferase I macrophage inflammatory protein l a

11

Miplb

macrophage inflammatory protein 1~

11 11 11

Mmv-16 Mmv-17 " M n s - I 1"

MCF endognenous virus-16 MCF endognenous virus-17 minor satellite Chr 11 (centromeric)

Probeb

pMCK19a, pMCK19b, Ichinose pMCK19c, pMCK19d Ichinose pKE1, tnxgaeC1, probe C12 Lussier XEB1, pEB1, done 4 co:A Matsushiro pLIFNK3 Gearing pLIF7.2b, pLIFmutl Gearing pLIF7.2b Gough pLI Fmut 1 K ol a [H] LIF genomic Gough kMLIF3.1, kMLIF20.0 Stahl pmGlcNAc-TI + Pownall clone 32, clone 52 Davatellis L2G25B (L2G25#4) Kwon Mip I a-genomic Grove MIPl-alphaTy-5 Brown " + co:G Zurawski Mipla eDNA, kMIP-la Widmer MuMIP clone 52 Davatellis MuMIP clone 32 Davatellis MIPl-beta/H400 Brown + co:G Zurawski L2G25C Sherry MCF100 + Frankel MCF100 + Frankel pMR150 Voliva co:VM C h a p m a n co:ND Hastie p9-1-2 Munke pMov-9 + co:R Jaeniach Jr co:Chumakov probe CS, pTK10fT, p9-1-2 co:R Jaenisch

1-I Mov-9

Moloney leukemia virus-9

11 Mov-13 11 Mpmv-2

Moloney leukemia virus-13 (see Cola-l) modified polytropic murine leukemia virus-2 JH modified polytropic routine leukemia virus-4

11

Mpmv-4

RFLVc C a n t a ~

JS-4

+ + +

JS-4

11

Mpmv-8

11

Mpmv-15

JS-4, M C F I 0 0 pMo-MCFl-16 modified polytropic murine leukemia virus-8 JS-4 JS4 JH modified polytropic murine leukemia virus-15 JS-4

11

Mpmv-18

JS4 modified polytropic murine leukemia virus-18 JS-4

11

Mpo

myeloperoxidase

+ + + + + +

+ + +

mMPO6 Mpo genomic Mpo eDNA [H] pGM706 +

I/ 11 11 11 11

11

11

MMMPO (microsat) MMMPO (microsat) "Ms3-2-20-Pl" minisatellite 3-2-20-P1 (human D3S45) pEFD134.7 "Ms3-2-21-P2" minisatellite 3-2-21-P2 (human D3S45) pEFD134.7 "Ms6-1-3-PI" minisatellite 6-1-3-P1 (human D14S1) pAW101 "Msl0-1-10-PI" minisatellite 10-1-10-P1 (human D17S5) pYNZ22 Mtv-3 m a m m a r y tumor virus locus-3 MMTV eDNA MTV-LTR E-P MTV-GR40 ev-8, pvc-28 MMTV8-21,MMTV8-29 MMTV 8-21 MMTV 8-29 MMTV cDNA or DNA MMTV (GRS/A) pTZ18R-ORF MMTVS', MMTV3' Myhs myosin heavy chain, skeletal muscle JR] I)82, [R] Myhs eDNA [R] plO3 [R] p82, [R] plO3 [HI pSMHCA Myh-1 probe Myhs-e myosin heavy chain, skeletal muscle, pMHC2.2 embryonic

+ + + + + + + + + + + + + + + +

+ +

pMHC2.2, Myhs-e e D N A Myhs-e c D N A (EB cells)

Frankel co:W Frankel Frankel Frankel co:M Vogt Frankel Frankel co:W Frankel Frankel Frankel Frankel co:W Frankel Venturelli Venturelli Friedman Morishita co:Morishita co:JA Todd co:JA Todd Julier Julier Julier Julier Michalides Michalides Michalides ce:Michalides Majors Eicher Eicher co:J Ball, J Majors co:H Diggelmann co:JE Majors co:G Peters Nudel Katcoff Czoanek co:L Leinwand eo:N Copeland Weydert Weydert Robbins

Referencee

Gene 1989; [email protected] Gene 1989; [email protected] Gene 1989; 85:435 ref:Iehinose, Gene 1988; 70:85 N u d Acid Ras 1988; 1619857 FMBO J 1987; 6:3995 PNAS 1988; 85"2627 Growth Factors 1990; 2:235 PNAS 1988; 85:2623 J Biol Chem 1990; 265:9833 Genomics 1992; 12:699 J Exp Meal 1988; 167:1939 PNAS 1989; 86:1963 N u d Acid Res 1990; 18:5561 J Immunol 1989; 142:679 rof:Wilson, J Exp Med 1990; 171:1301 J Immuno11991; 146:4031 J Exp Med 1~8; 167:1939 J Exp Med 1988; 167:1939 J Immunol 1989; 142:679 tel:Wilson, J Exp Meal 1990; 171:1301 J Exp Med 1988; 168:2251 M a m m Genome 1992; 2:110 M a m m Genome 1992; 2:110 Nucl Acid Pea 1983; 11:8847 ref:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, N u d Acid IRes 1983; ii:6965 Cytogenet Cell Genet 1986; 43:140 ref:Chumakov, J Virol 1982; 42:1088 ref:Buchberg, Genetics 1989; 122:153 refiJahner, Molec Cell Biol 1985; 5:2212 Genetics 1990; 124:221 ref.'Geratein, Cell 1990; 63:537 Genetics 1990; 124:221 M a m m Genome 1992; 2:110 ref:Blatt, PNAS 1983; [email protected] Genetics 1990; 124:221 M a m m Genome 1992; 21110 ref:Gerstein, Cell 1990; 63:537 Genetics 1990; 124:221 M a m m Genome 1992; 2:110 Genetics 1990; 124.221 ref:Prochazka, Mouse Genome 1991; 89.258 Nucl Acid Res 1989; 1715852 Nucl Acid Res 1989; 1717987 Blood 1991; 78:2426 J Biol Chem 1987; 262:3844 refiBuchberg, Genetics 1989; 122:153 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 11255 PNAS 1990; 87:4585 PNAS 1990; 87:4,585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 Virology 1985; 142:278 Virology 1985; 142:278 Virology 1985; 142:278 ref:Moen, M a m m Genome 1991; 1:217 Nature 1981; 289:253 Genetics 1990; 125:431 Genetics 1990; 125:431 ref:MacInuea, Virology 1984; 132112 ref:Hainaut, Cane Res 1990; 50:3754 ref:Pullen, J Exp Med 1992; 175:41 ref:Fairchild, Immtmogenetics 1991; 34:227 Nucl Acid Res 1980; 8:2133 PNAS 1980; 77:96O EMBO J 1982; 1:1299 ref:Munke, J Mol Evol 1987; 251134 ref:Buckwalter, Genomics 1991; 10:515 PNAS 1985; 82:7183 Cell 1987; 4~.121 J Biol Chem 1990; 265:11905 Continued on next p a g e

J.T. Eppig: Clones and Probes

367

Table 3. Continued. Chr Symbola

Locus Name

Probe b

11

Myhs-f

myosin heavy chain, skeletal muscle, adult fast

11

Myhs-p

11

Myla

myosin heavy chain, skeletal muscle, perinatal myosin light chain, alkali, cardiac atria

11

Nfh

neurofilament, heavy polypeptide

11

Ngfr

nerve growth factor receptor

11

Pad-1

MMTV LTR integration site

11

Pdeg

cGMP-phosphodiesterase T (rd/rd mice) " (+/+mice)

Pkca

protein kinase C, a subunit

Pmv-2

polytropic murine leukemia virtm-2

Pmv-22 Pmv-46 Pmv-56 Pmv-58 Rflra

polytropic murine leukemia polytropic murine leukemia polytropic murine leukemia polytropie murine leukemia retinoic acid receptor a

Rel

reticuloend otheliosis oncogene

11

Rnula-1

U l a l small nuclear 1LNA

11

Rnula-ps

U l a l small nuclear RNA pseudogene

11

Rnu3 b- 1

U3B small nuclear RNA-1

11

Rnu3b-2

U3B small nuclear I~NA-2

H

virus-22 virus-46 virus-56 virus-58

RFLVc C o n I ~xl

pMHC32, Myhs-f eDNA pMHC32 + + + Myhs-f probe + JR] M H C 1 5 pMHCI6.2A + p M H C 16.2A, Myhs-p c D N A pGLC260 (=pC6) + + +

Weydert Weydert Weydert co:Weydert Robert Czosnek Weydert Weydert Lonai co:Barton Robert

pOLCAS0

Robot

pGLCAS0, pC6 pCll0.4, ~.ELC1, kECL2 pMyla p21H MLCIA M M L C I A (microsat) (micrcsat) cos3A 1

Barton Barton + co:Barton Cohen-Haguenauer + co:S Gisselbrecht + cn:JA Todd + co:JA Todd co:F Greaveld Julien " (Kpnl/Sall frag) + co:JP Julien cos2Al, cealA1, % N F - M co:F Grosveld k5A co:WW Schlaepfer JR] pNF-H I Mattei p~ Buck + co:Buck pPad-1 + co:A Sonnenberg + co:A Sonnenberg Pdeg eDNA1, Pdeg eDNA2 co:DB Farber Pdeg eDNA3, Pdeg eDNA4 co:DB Farber Pdeg eDNA5 co:DB Farber unnamed Tuteja cGMP-PDET eDNA Farber

Pkca cDNAI, Pkca cDNAII Rose-John pbPKC-a21 Parker + co:Parker MCG-1, MCG-3, MCG-5 co:GS McKnight Pkca probe (-204 to 2647) Ohno " Wada JS-5 + Frankel + Frankel JS-5 + Frankel JS-5 + Frankel JS-5 + Frankel JS-5, MCF100 + Frankel mRARa-cDNA co:P Chambon Matted m R A R - a l , mRAR-a2, Leroy mRAR-a3, mRAR-a4, Leroy mRAR-a5, mRAR-a6, Leroy mRAR-a7, mRAR-aNS Leroy ~.G1, ~.G2, kG3 Leroy clone 2-20-4 Chen + co:Chen [HI pHHS tel-l, v-rel Brownell [HI pHHS + co:N Rice [H] pHHS rel-1 + co:N Rice + Pownall v-re] + co:Browne] Lm-rell, ~.m-rel2 co:S Gerondakis pUI~36 + co:Michael pUla-236, pUla-261 Howard pUla-214 Howard U1 RNA-specific probe Schenborn Luud pUP325 Michael pU1-t~325 Howard ~.13, pEU3.1, pSHU3.1 Mazan cos15, 7~13 Mazan probe P, probe U Mazan ~.13, pEU3.2 Mazan cosl5, ;~13 Mazan probe P, probe U Mazan

Refe~ncee

Cell 1987; 49:121 PNAS 1985; 82:7183 J Biol Chem 1983; 258:13867 ref: Buchberg, Genetics 1989; 122:153 Nature 1985; 314:181 EMBO J 1982; 1:1299 PNAS 1985; 82:7183 Cell 1987; 49.121 DNA 1987; 6:409 J Muscle Res Cell Motl 1985; 6:461 Nature 1985; 314:181 personal communication J Biol Chem 1985; 260:8578 d Biol Chem 1988; 263:12669 ref:Buchberg, Genetics 1989; 122:153 Hum Genet 1989; 81:278 ref:Sola, J Virol 1988; 62:3973 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 ref:Julien, Mol Brain Res 1986; 1:243 C-ene 1988; 68:307 ref:Kaupmann, Genomics 1992 (in press) ref:Judien, Mol Brain Res 1986; 1:243 ref:Shneidman, Mol Brain Res 1992; 13:127 Mouse News Lett 1989; 84."96 Dev Brain Res 1988; 44:259 ref:Btmhberg, Genetics 1989; 122:153 ref:Buchberg, Genetics 1989; 122:153 ref:Buckwalter, Genomics 1991; 10:515 ret2Tuteja, Exp Eye Res 1989; 48:863 ref:Tuteja, Exp Eye Re~ 1989; 48:863 refiTuteja, Exp Eye Res 1989; 48:863 FEBS Lett 1988; 232:182 In:Inherited and Environmentally Induced Retinal Degenerations, Alan Liss, 1989; p 143 Gene 1988; 74:465 Science 1986; 233:853 ref: Buchberg, Genetics 1989; 122:153 rel~Chrivia, J Biol Chem 1988; 263:5739 Nature 1987; 325:161 BBRC 1989;, 165:533 J Virol 1989; 63:3810 M a m m Genome 1992; 2:110 J Viro11989; 63:3810 J Virol 1989; 63:3810 J Virol 1989; 63:3810 M a m m Genome 1992; 2:110 ref:Zelent, Nature 1989; 339:714 Genomics 1991; 10:1061 EMBO J 1991; 10:59 EMBO J 1991; 10:59 EMBO J 1991; 10:59 EMBO J 1991; 10:59 EMBO J 1991; 10:59 J Virol 1982; 45:104 rof:Buchberg, Oncogene Res 1988; 2:149 Mol Cell Biol 1985; 5:2826 ref:Keir, Genomics 1991; 9:390 ref.'Kaupmaun, Genomics 1992 (in press) Genomics 1992; 12:699 ref:Buchberg, Genetics 1989; 122:153 ref:Grumout, Oncogene Res 1989; 4:1 Somatic Cell Mol Genet 1986; 12:215 Nuc] Acid Res 1986; 14:9811 Nucl Acid Res 1986; 14:9811 Nucl Acid Res 1985; 13:6223 Somatic Cell Mol Genet 1988; 14:143 Somatic Cell Mol Genet 1986; 12:215 Nucl Acid Res 1986; 14:9811 J Biol Chem 1988; 263:19461 Gene 1990; 94:263 C y t ~ n e t Cell Genet 1991; 56:18 J Biol Chem 1 ~ ; 263:19461 Gene 1990; 94:263 Cytogenet Cell Genet 1991; 56:18 C o n t i n u e d on next page

368

J.T. Eppig: Clones and Probes

Table 3. Continued. Chr Symbola

11

Rnu3b-3

11

Rnu3b-4

11

Rpo2-1

H

Shbg

11

Sigje

11

Sparc

Locus Name

Pt~

RFLVc C o n i ~ d

~.19, pEBU3.3 probe P, probe U coslS, pSU3.4 U3B small nuclear RNA-4 probe P, probe U Rpo2-1 genomic RNA polymerase II-1 BE2.9, pill9-4, pH22-1 pE26-7, pE26-4, pHRPII pEE14.3, kGA1, pEXRPII3' Rpo2-1 genomic-1 Rpo2-1 genomic-2 pBE2.9 + pEXRPII3' pHRPII, pEEl4.3 pE26-7, pE26-4, % G A 1 pE26-7 MMRPOII2 (microsat) + [R] ABP cDNA sex hormone binding globulin + + small inducible gene JE pBC-JE JE + + pcJE-1 74 MMGFJE (microsat) + + secreted acidic cysteine rich glycoprotein pPE2'20 + (osteoneetin) + + + pC33 + pF9.33, pF9.52 pF9.54, pPE.30 p30g3, pcosSP13 U3B small nuclear RNA-3

SPARC probe [H] osteonectincDNA

H 11

Syb-2 Tea-3

synaptobrevin-2 T-cell activation family-3

(alternate splice of Tca-3, PS00) "TgTtr-2" flank of h u m a n TTR transgene insert-2 (from normal DBA/2J) (from normal DBA/2J) (from normal BALB/cJ) 11 Thbp thyroid hormone binding protein (p55) 11

11 Tk-1

thymidine kinase-1

12

transformation-related protein 53

Trp53

Mazan Mazan Mazan Mazan Pravtcheva co:JL Corden co:JL Corden co:JL Corden co:JL Corden Bartolomei co:M Bartolomei Bartolomei Bartolomei Bartolomei co:J Corden co:JA Todd Joseph Joseph Pownall Cochran Rollins co:CD Stiles co:B Rollins Rollins co:JA Todd co:JA Todd Mason Mason Elliott co:NM Gough Holland co:M Young Mason Mason co:BLM Hogan

+ co:B Hogan + co:MYoung

[H] VP57-1 TCA3.0,TCA3.1.2,TCA3.1.4 TCA3.1.2, TCA3.1.4 TCA3.0 + PS00 eDNA TCA3.0 + kTG1, kTG2, kTG4 + kDBA102, kDBA108, kDBA103, %DBA13 ),BALl, kBAL2 p55 cDNA [HI pHTB pMtk4,pMtk9 pMtk116, pMtk322 pMtk535, pMtk536 TK cosmid A, TK cosmid B pMTK4 + cosmids 322-1,322-2, 536-2, cosmids 535-1F, 535-2,536-1 pp53-298 pp53-203 pp53422, pp53-271 pp53-532, pp53-208, Ch53-2 pp53-176, pCh53-16 pp53-208, pp53-422 pp53-271, pCh53-11 ~53-176 p27.1a, plIb, pP53-5 p27.1a + + Ch53-7, Ch53-16 p53-c19 § + + LTRp53 CG3 Trp53 genomic pM8 +

Archer Burd co:ME Doff co:ME Dorf Brown Dorf Sasaki Sasaki Sasaki Sasaki Gong co:S-Y Cheng Li n Li n Lin co:E Wintersberger co:ATCC Lin Lin Hozier Oren co:AJ Levine Oren Oren Zabut-Houri Zabut-Houri Zabut-Houri co:M Oren Jenkins co:A Bernstein co:JR Jenkins Bienz Benchimol co:A Bernstein eo:A Bernstein Ashworth eo:M Oren co:S Benchimol co:Wolf

Refinancee

J Biol Chem 1988; 263:19461 Cytogenet Cell Genet 1991; 56:18 Gene 1990; 94.'263 Cytogenet Cell Genet 1991; 56:18 Somatic Cell Mol Genet 1986; 12:523 ref:Bartolomei, Mol Cell Biol 1987; 7:586 ref:Bartolomei, Mol Cell Biol 1987; 7:586 ref:Bartolomei, Mol Cell Biol 1987; 7:586 ref:Bartelomei, Mol Cell Biol 1987; 7:586 Mol Cell Biol 1987; 7:586 ref:Buckwalte% Genomics 1991; 10:515 Mol Cell Biol 1987; 7:586 Mol Cell Riol 1987; 7:586 Mol Cell Biol 1987; 7:586 ref:Miernicki, PNAS 1990; 87:4680 ref:Hearne, M a m m Genome 1991; 1:273 PNAS 1991; 56:122 Cytogenet Cell Genet 1991; 56:122 Genomics 1992; 12:699 Cell 1983; 33:939 PNAS 1988; 85:3738 ref: Smith, Cytogenet Cell Genet 1989; 52:194 ref:Wflson, J Exp Med 1990; 171:1301 Mol Cell Biol 1989; 9:4687 ref:Aitman, M a m m Genome 1991; 1:206 ref:Baldacci, Maram Genome 1992; 2:100 EMBOJ 1986; 5:1831 EMBO J 1986; 5:14&5 Genomics 1990; 8:591 refiBarlow, EMBO J 1987; 6:617 J Biol Chem 1987; 105:473 ref:Buckwalter, Genomics 1991; 10:515 EMBO J 1986; 5:1465 EMBO J 1986; 5:1465 ref:McVey, J Biol Chem 1988; 263:11111 ref:Cheng, DNA 1987; 6:401 ref:Baldacci, M a m m Genome 1992; 2:100 J Biol Chem 1990; 265:17267 J Immunol 1987; 139:3126 ref:Wilson, J Exp Meal 1990; 171:1301 ref:Wilson, J Exp Med 1990; 171:1301 J Immunol 1989; 142:679 ref:Wilson, J Exp Med 1990; 171:1361 Development 1991; 111:573 Development 1991; 111:573 Development 1991; 111:573 Development 1991; 111:573 Nucl Acid Res 1988; 16:1203 ref'.Morris, M a m m Genome 1991; 1:263 Mol Cell Biol 1985; 5:3149 Mol Cell Biol 1985; 5:3149 Mol Cell Biol 1985; 5:3149 Seiser, Nucl Acid Res 1989; 17:185 refiMartiniuk, M a m m Genome 1991; 1:287 Mol Cell Biol 1985; 5:3149 Mol Cell Biol 1985; 5:3149 Genomics 1991; 10:827 PNAS 1983; 80:58 refiMunke, J Mol Evol 1987; 25:134 EMBO J 1983; 2:1633 EMBO J 1983; 2:1633 Nature 1983; 306:594 Nature 1983; 306:594 Nature 1983; 306:594 ref:Czosnek, Mol Cell Biol 1984; 4:1638 Nucl Acid Res 1984; 12:5609 reflNadeau, Genomics 1990; 8:469 refiColombe, M a m m Geneme 1992; 2:136 EMBO J 1984; 3:2179 Cancer Cells 2; Cold Spring Harbor 1984 refiBuchberg, Oncogene Res 1988; 2:149 refiBuchberg, Genetics 1989; 122:153 Genomics 1989; 4:323 refiRuggeri, Cane Res 1991; 51:6615 reflRovinski, Mol Cell Biol 1987; 7:847 refiMoen, M a m m Genome 1991; 1:217 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

369

Table 3. Continued. Chr Symhda

11

Wnt-3

11

Wnt-3A

11 11 11 11 11 11

Xmmv-77 Xmv-20 Xmv-42 Xmv-47 Xmv-49 Zfp-2

11

Zfp-3

~

Name

Probeb

RFLVc C o n t ~d

(rearranged Trp53, p44) ~.53-22 wingless-related MMTV integration site-3 ~BGll, ~.BG15, ~.BG28 :~BG51/52, ~.BG54/55 kM6, ~BG66, ;~BG81/83 pBG14, pBGS1, pBCct2 pBG46, pBC-87, pBG88 pBGgO, pBG89 psi7 Wnt-3 eDNA wingless-related MMTV integration site-3A Wnt-3A eDNA clone 9A, clone 15A xenotropic-MCF leukemia virus-77 pXenv, pMo-MCFenv xenotropic routine leukemia virus-20 JS-6~IS-10 xenotropic murine leukemia virus-42 JS-6flS-10 xenotropic routine leukemia virus-47 JS-6+JS-10, XENOII2 xenotropic routine leukemia virus-49 JS-6+JS-10, XENOl12 zinc finger protein-2 ~.mkr2 cmKr2A, cmKr2B pKCA] zinc finger lprotein-3 pmFP1, lpE10 pE10

Aat

a-l-antitrypsin

pC1.2

co:S Benchimol Reelink Roelink Roelink Roelink Roelink Roelink Roelink Gavin Gavin Roelink + Frankel + Frankel + Frankel + Frankel + Frankel Chowdhury Chowdhury + Nadeau + eo:Willison + co:Willison + Ashworth + Nadeau + + + + +

LVA301 ~A,~B,~.C,~.D ~H,ZM,kN lpliv3,pliv3b lp1796 4-

pG3.5

+ +

12

Akt

thymoma viral iproto-oncogene

AAT full length cDNA pvaktl +

12 A m h - r s 4 12 Apob

anti-Mullerian hormonerelated seq-4 alpo]ipolpretein B

12

creatine kinase-3, brain

[R] pRMISI JR] ApobcDNA Apob genomic [H] pCPK-B

cysteine-rich intestinal protein

Ck-3 genomic [R] BCK [R] pRI3

Ck-3

+ +

+

12

Crilp

+

+ + +

12 12

Dl2Lehl Dl2Mcgl

DNA segment, Chr 12, Lehrach-1 DNA segment, Chr 12, Med Cell of Ga-1

12

DI2NI

DNA segment, Chr 12, NIH-1

pMI3 PCR Line 6589 phage clone 1 pRC2.3 (from clone 1) DAbI-12

12

D12Nyul

DNA segment, Chr 12, NYU-1

M13p7-97

+ + + + + + +

M13~7-97

+ +

12

D12Nyu2

DNA segment, Chr 12, NYU-2

M13plg-25

+ + + +

M13~19-25 (=M13p19-25) + 4-

12

D12Nyu3

DNA segment, Chr 12, NYU-3

M13p20-1

12

D12Nyu4

DNA segment, Chr 12, NYU-4

M13p2615

DNA segment, Chr 12, NYU-5

M13~2615 (=M13p2615) M13p30-3

+ + + +

12

D12Nyu5

+ + + +

M13~30-3 (=M13p30-3)

+

co:P D'Eustachio co:P D'Eustachio co:P D'Eustachio co:P D'Eustachio co:P D'Eustachio Clissold

Krauter Krauter Krauter Hill co:RW Elliot co:P D'Eustachio Eicher Sifers Staal co:S Staal co:RL Care, Biogen Lusis Smith Mariman co:ECM M a r i m a n co:B Wieringa co:P Benfield Birkenmeier Birkenmeier co:EH Birkenmeier Birkenmeier Cox co:P Leder co:P Leder Bauer co:K Huppi co:P D'Eustachio co:P D'Eustachio co:P D'Eustachio co:PD D'Eustachie co:P E'Eustachio co:P D'Eustachio co:P D'Eustachio co:P D'Eustachio co:P D'Eustachio co:P D'Eustachio co:P E'Eustachio Davisson co:P D'Eustachio Eicher co:P D'Eustachio co:P D'Eustachio co:P E'Eustachio co:P D'Eustachio co:P D'Eustachio co:P D'Eustachio co:P E'Eustachio

Refel~meee

ref:Rovinski, Mol Cell Biol 1987; 7:847 PNAS 1990; 87:4519 PNAS 1990; 87:4519 PNAS 1990; 87:4519 PNAS 1990; 87:4519 PNAS 1990; 87:4519 PNAS 1990; 87:4519 Genes & Development 1991; 5:381 Genes & Development 1990; 4:2319 Genes & Development 1990; 4:2319 Genes & Development 1991; 5:381 M a m m Genome 1992; 2:110 J Virol 1989; 63:1763 J Virol 1989; 63:1763 M a m m Geneme 1992; 2:110 M a m m Genome 1992; 2:110 Cell 1987; 48:771 EMBO J 1988; 7:1345 Genomics 1990; 8:469 refiAshworth, Mouse News Lett 1987;79:84 1 s t Inter Worksh on Mouse Gene Map 1987 Genomics 1989; 4:323 Genomics 1990; 8:469 J Exp Med 1984; 160:827 PNAS 1989; 86:5035 ref:Dickinson, Genomics 1990; 6:505 ref: Seldin, Genomics 1989; 5:24 refi Glaser, Genomics 1989; 5:510 Gene 1981; 15:225 DNA 1986; 5:29 DNA 1986; 5:29 DNA 1986; 5:29 Mol Cell Biol 1985; 5:2114 ref:Birkenmeier, PNAS 1988; 85:8121 tel:Blank, Genetics 1988; 120::1073 Genetics 1990; 125:431 Genomics 1990; 6:100 PNAS 1987; 84:5034 Cho, M a m m Genome 1991; 1:30 refiKing, Genomics 1991; 11:273 J Biol Chem 1987; 262:7594 Gene 1990; 87:309 Genornics 1987; 1:126 ref:Cho, M a m m Genome 1991; 1:30 ref:vanDeursen, Genomics 1991; 12:340 ref:Lyous, Development 1991; 113:1017 PNAS 1986; 83:2516 PNAS 1988; 85:8121 ref:Cho, M a m m Genome 1991;i 1:30 PNAS 1986; 63:2516 Genomics 1991; 10:375 Nature 1981; 293:198 ref:Cobb, Biochem Genet 1987; 25:401 Nucl Acid Res 1988; 16:8200 refiCho, M a m m Genome 1991; 1:30 J Exp Med 1984; 16ff~27 PNAS 1989; 86:5035 ref: Seldin, Genomics 1989; 5:24 tel:Knight, Mol Cell Probes 1990; 4:497 ref:Blank, Genetics 1988; 120:1073 ref: Glaser, Genomics 1989; 5:510 J Exp Med 1984; 160.'827 ref: Seldin, Genomics 1989; 5:24 ref:Siraeusa, Genetics 1991; 127:169 refiDavisson, Genomics 1991; 9:778 tel:Blank, Genetics 1988; 120:1073 Genomics 1991; 9:778 J Exp Meal 1984; 160:827 Genetics 1990; 125:431 J Exp Med 1984; 16~.827 ref: Seldin, Genomics 1989; 5:24 refiBlank, Genetics 1988; 120:1073 J Exp Med 1984; 16~.827 ref: Seldin, Genomics 1989; 5:2.4 refiSiraeusa, Genetics 1991; 127:169 tel:Blank, Genetics 1988; 120:1073 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

370 Table 3. Continued. Chr Symbola

12 12 12 12 12 12 12 12

12

12 12 12 12

12

12

].z~us Name

Pt~ r

IL~LVc Coniactd

Refer~cee

co:P E'Eustachio refiBlank, Genetics 1988; 120:1073 ref:Blank, Genetics 1988; 120:1073 co:P E'Eustachio tel:Blank, Genetics 1988; 120:1073 co:P D'Eustachio ref:Blank, Genetics 1988; 120:1073 co:P D'Eustaehio rel~Blank, Genetics 1988; 120:1073 eo:P D'Eustachio Eicher Genetics 1990; 125:431 DI2Rp54 DNA segment, Chr 12, Roswell Park-54 pLV54 Mouse News Letter 1982; 67:36 Hill Eif4e eukaryotic translation initiation factor-4e If4e eDNA Altmann J Biol Chem 1989; 264:12145 probe A, prdae B, probe C co:N Sonenberg ref:Jaramillo, J Biol Chem 1991; 266:1044( Fos FBJ osteosarcoma oncogene [V'J pfesl + co:Curran J Virol 1982; 44:674 + eo:B Taylor ref:Birkenmeier, PNAS 1988; 85:8121 + co:I Verma ref:D'Eustachio, J Exp Med 1984; 160:827 + co:P E'Eustachio ref:Blank, Genetics 1988; 120:1073 + co:ATCC ref:Diekinson, Genomics 1990; 6:505 [V] pv-fo6-1 co:M Shibuya, T Yamaoto refiTodokoro, BBRC 1986; 135:1112 pc-fos(mouse)-I VanBeveren Cell 1983; 32:1241 ~.c-los(mouse)-2 VanBeveren Cell 1983; 32:1241 pc-los(mouse)-201 VanBeveren Cell 1983; 32:1241 [V] pFBJ-2 VanBeveren Cell 1983; 32:1241 Collart J Immuaol 1987; 139:949 clone P49 Almendral Mol Cell Biol 1988; 8:2140 pc-los(rose)-3 Miller Cell 1984; 36:51 co:I Verma ref: Glaser, Genomics 1989; 5:510 3'flank (includes estrogen response) 3'Fos genomic SM Hyder Gene 1991; 105:281 Fv-4 Friend virus susceptibility-4 RR2, RR7, RR24 Dandekar J Virol 1987; 61:308 pRR-E, RR24-B Dandekar J Virol 1987; 61:308 pEc-env (MuLV env) Kozak PNAS 1984; 81:834 pFv4 co:H Ikeda ref:Masuda. J Virol 1990; 64:1033 co:H Ikeda ref:Dandekar, J Virol 1987; 61:308 Hsp84-3 heat shock protein, 84kDa-3 done A, clone B Moore Gene 1987; 56:29 Hsp86-1 heat shock protein, 86kDa-1 eDNA-4.10, eDNA-4.8 Hoffmann Gene 1988; 74:491 clones 1, 2, 3,4 Moore J Biol Chem 1989; 264:5343 Ifi12 interferon activated gene 12 12 gene eDNA, 12 gene probe co:Lengyel ref:Opdenakker, Virology 1989; 171:568 Igh immunoglobulin heavy chain complex pIVSII Bosma Curt Top Microbiol Iramunol 1988; 137:19' MMIGMUD3 (microsat) + co~A Todd ref:Hearne, M a m m Genome 1991; 1:273 (microsat) + co:JA Todd ref'.Montagutelli, M a m m Genome 1991; 1: MUSIGHAB2 (microsat) + co:JA Todd ref:Hearne, M a m m Genome 1991; 1:273 (microsat)+ co:JA Todd ref:Montagutelli, M a m m Genome 1991; 1: MMIGHYB1 (microsat) + co:JA Todd ref:Hearne, M a m m Genome 1991; 1:273 MMIGVH23 (microsat) + c~:JA Todd ref:Hearne, M a m m Genome 1991; 1:273 MIGHVJ2 (microsat) + co:JA Todd ref:Hearne, M a m m Genome 1991; 1:273 Igh-l(y2a) immunoglobulin heavy chain, (C~2a) ME768 Roeder PNAS 1981; 78:474 ChM.Igy2a-32, ChM.Ig32a-9 fihimizu Nature 1981; 289:149 Shimizu Cell 1982;28:499 ChM.Ig72a-11 Shimizu Nature 1981; 289:149 Shimizu Cell 1982;28:499 ChMT2a-9 ho:T Honjo ref:Eckhardt, Mol Cell Biol 1985; 5:856 ICRg.7.1, ICR9.9.2.1 ho:LA Eckhardt ref:Gilmore, J Immunol 1987; 139:619 gtl0.Vll.19.3 ho:BK Birshtein ref:Gilmore, J Immunol 1987; 139:619 ST2a-3, Ch9.7.1 ho:BK Birshtein ref:Eckhardt, Mol Cell Biol 1985; 5:856 p'tSa-3 Brown Mol Cell Biol 1987; 7:450 p72a- 1 + Mowatt J Immunol 1986; 136:2674 pAB~2a-1 Bothwell Cell 1981; 24.'625 co, mid G2a-2, pSG2a-150 Ollo PNAS 1981; 78;2442 pBG2a-4, pG2a- 10-21 Ollo PNAS 1981; 782442 pG2a-10-21 Affray Gene 1980; 12:77 co:F Rougeon ref:Ollo, N u d Acid Res 1981; 9:4099 co:J-L Sikorav refiSikorav, Nuel Acid Res 1980; 8:3143 pG2a-10-21, pG2a-10-99 Affray Nucl Acid Res 1980; 8:1231 pM173T2a.15 , pM173~a.20 A d a m s Biochemistry 1980; 19:2711 pHl~2a.8, pHl~2a.17 Adams Biochemistry 1980; 19:2711 Igh-1 eDNA Lang Nuel Acid Res 1982; 10:611 Igh-2(a) immunoglobulin heavy chain, (Ca) CHSpa29, CHSpa22, D avis Nature 1980; 283:733 CH603a125, CH603a6 Davis Nature 1980; 283:733 pM603a.8, pS107a.4 Adams Biochemistry 1980; 19:2711 Ch603r Early PNAS 1979; 76:857 p603a1, pl07aRS, pl07aR6 Early PNAS 1979; 76:857 Ch603a6,Ch603a125,pl O7aR5 Early Cell 1980; 19:981 ChM 167a10,ChM603a6,ChSpa29 Kim Cell 1981; 27.'573 IMp]clone 1A Osborne Genetics 1988; 119:925 pa558~, pa48.16 Auffray Cene 1981; 13:365 pc~J558)13 + Marcu Cell 1980; 22:187 Brown Mol Cell Biol 1987; 7:450 (=pJ558) co:K Marcu tel:Osborne, Genetics 1988; 119:925 co:K Marcu ref:Tucker, PNAS 1981; 78:7684 M70, M41, M63, M64, M67 M a r c u Cell 1980; 22:187 D12Nyu6 D12Nyu7 D12Nyu8 D12Nyu9 D12Nyul0

DNA segment, Chr DNA segment, Chr DNA segment, Chr DNA segment, Chr DNA segment, Chr

12, NYU-6 12, NYU-7 12, NYU-8 12, NYU-9 12, NYU-IO

pBl~9-9 pBR~9I~ pUC&38H10 pUC~ 57UXI7 pUCC43G14

+ + + + + + +

Continued on nex~

J.T. Eppig: Clones and Probes Table 3.

371

Continued.

Chr Symbola

12 Igh-2(a)

LocusName

immunoglobulin heavy chain, (Ca)

flank of Igh-2

12 Igh-3(72b) immunoglobulin heavy chain, (C72b)

12 Igh-4(71)

immunoglobulin heavy chain, (CT)

Probeb

RFLVc Contac~t

M67-19 Brown Ch4A142.4, Ch4A140.7 Tucker Ch30M.Iga-3, Ch30M.Iga-13 Nishida Shimizu ChM.Iga-8, Ch30M.Iga-27 Nishida Shimizu p3'a Stavnezer + co:J Stavenezer + co:P D'Eustachio + eo:P D'Eustachio M141-p21, MEP3 Sakano MEP3,MEP12,MEP5,ME593 Roeder MEP52dEP8,MEP3,141p21 Maki D'Eustachio T2b eDNA p"f2b(11)7 Schibler Brown py2b/7 co:R Perry, K Marcu RBL216 ho:RB Lang ho:LA Eckhardt ICR9.7.1 ho:BK Birshtein gtl0.Vll.19.3 pBR1.4, [r12b(ll)7, M68 Lang pBR1.4 Brown pAB?2b-1 Aft Bothwell C62, RBL216, SL1, SL59 Lang ChM.IgT2b-69, ChM.Ig72b-2 Shimizu Shimizu plgH22 O11o eo:J-L Sikorav + co:T Honjo pIgH22, IgH22 co:T Hongo kgtWES-T2bC57 Ollo pBR322-T2b, Igh-3 probe Ollo pT2b/E6.6 + Mowatt pBR322.IgH22 co:T Honjo pBR322.IgH2201 co:T Honjo kgtWES.IgH2201 co:T Honjo kgtWES.IgH22, pG2b-4 co:T Honjo ;~gtWES.IgT2b-2203 Kataoka Ig72b-22, pIg72b-23 Kataoka kgtWES.IgT2b-2206 Kataoka pIgy2b-26, pIfff2b-2204 Kataoka pIgT3-30 Kataoka Igh-3 eDNA 9 ho:P Scheier pV(ll)l, pV(ll)2 Zakut pV(11)7 co:R Perry pSVgptMPC11(H)XR co:SL Morrison MEP1OA, MEP10E Roeder MEP15, MEP10 Roeder MEP10 co:CL Schildkraut MEP1, MEP15 Maki ChM.Igy1-13,Ch30M.Ig71-6 Takahashi " Shimizu ChM.IgT1-3, ChM.IgTl-17 Shimizu Shimizu ChM.Ig71-704, pGI-6 co:T Honjo ChM.Igyl-706 co:T Honjo IgH7, IgH2, plgH7 co:T Honjo XgtWES.IgH2 Ollo co:T Hongo 93G7 + Sims I23, IV92 co:M Fougereau pG1.6 co:T Honjo pM21T1.1 Adams pABTI-4, pABTI-1 Bothwell TM33 Mowatt Mowatt VhARS + Brodeur PT1/A5 Dunnick " Mowatt pT1/EH 10.0 + Mowatt PT1/P.A, pT1/B.T2, pT1/B.V1 Mowatt IgH2, pB1L322.IgH2, pG1-6 Honjo IgH2 + co:T Honjo

Refe~e~ee

Mol Cell Biol 1987; 7:450 PNAS 1981; 78:7684 PNAS 1981; 78:1581 Cell 1982;28:499 PNAS 1981; 78:1581 Cell 1982;28:499 ref:Brewn, Mol Cell Biol 1987; 7:450 ref:Blank, Genetics 1988; 120:1073 PNAS 1989; 86.'~35 ref:Cho, Mammal Genetics 1991; 1:30 Nature 1980, 286:676 PNAS 1981; 78:475 PNAS 1980; 77:2138 J Exp Med 1980; 151:1546 Cell 1978;15:1495 Mol Cell Bio] 1987; 7:450 ref:Rabhitts, Nature 1980; 283:351 tel:Gilmore, J Immunol 1987; 139:619 tel:Gilmore, J Immunol 1987; 139:619 tel:Gilmore, J Immunol 1987; 139:619 Nucl Acid Res 1982; 10:611 Mol Cell Biol 1987; 7:460 Cell 1980; 20:293 Cell 1981; 24.'625 Nucl Acid Res 1982; 10:611 Nature 1981; 289:.149 Cell 1982;28:499 PNAS 1981; 78;2442 refiSikorav, Nuci Acid Res 1980; 8:3143 ref:Yaoita, Nature 1980; 286:860 ref:Yamawaki, Nature 1980; 283:786 Nature 1982; 298:767 Nature 1982; 298:767 J Immunol 1986; 136:2674 ref:Takahashi, Gene 1980; 11:117 ref:Takahashi, Gene 1980; 11:117 ref:Takahashi, Gene 1980; 11:117 ref.-Kataoka, PNAS 1983; 80:4997 Cell 1981; 23:357 Call 1981; 23:357 Cell 1961; 23:357 Cell 1981; 23:357 Cell 1981; 23:357 ref:Blankenstein, Eur J Immun 1987; 17:1351 Nucl Acid Res 1980; 8:3591 ref:Zakut, Nucl Acid Res 1980; 8:3591 refLWard, Mol Immunol 1992; 29:279 PNAS 1981; 78:475 PNAS 1981; 78:475 ref:Brown, Mol Cell Biol 1987; 7:450 PNAS 1980; 77"2138 Immunoglobulin Idiotypes 1981; pp123 Cell 1982;28:499 Nature 1981; 289:149 Cell 1982;28:499 ref.'Kataoka, J Biol Chem 1982; 257:277 rel~Kataoka, J Biol Chem 1982; 257:277 ref:Takahashi, Gene 1980; 11:]L17 PNAS 1981; 78;2442 ref.'Yamawaki, Nature 1980; 283:786 Science 1982; 216:309 ref:Schiff, Nucl Acid Res 1983; 11:4007 ref:Schiff, Nucl Acid Res 1983; 11:4007 Biochemistry 1980; 19:2711 Cell 1981; 24.~25 Nucl Acid Res 1985; 13:225 J Immunol 1986; 136:2674 Eur J Immunol 1984; 14.@22 Nucl Acid Res 1980; 8:1475 J Immunol 1986; 136:2674 J Immunoi 1986; 136:2674 J Immunol 1986; 136:2674 Cell 1979; 18:559 ref.'Yaoita, Nature 1980; 286:850 C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

372 Table 3.

Continued.

Chr S y n ~ a

~

Name

12 Igh-5 (5)

immunoglobulin heavy chain, (C8)

12 Igh-6(~)

immunoglobulin heavy chain, (Cg)

12 Igh-7(e)

immunoglobulin heavy chain-7 (Ca)

12 Igh-a(y3)

immunoglobulin heavy chain, (C~)

Probeb

pXllC p554J

R~LVc Coatac~

co:Tucker Tucker co:P Tucker co:S Strober Gh28-291.2, Ch28-188.1 eo:S Strober C81, C~3, CSH (fr p854J) co:P Tucker Ch28M.Igg-49, ChM.IgS-16 Shimizu ~.gtWES.M.IgB-89 Shimizu XgtWES.M.IgS-100 Shimizu ChM.Ig73-201, ChM.Ig~3-13 Shimizu ChM.Ig'f3-32 Shimizu CoaJ-17 Wood CHSp~7, CHSpg27 D a via ChS~27 Early Kim p104E~12 Davis pl04Ep.12, Ch603p35, C ala me ChSpp.27, ChSpg7, pSp~kl Calame p S I ~ I , pGATS0 Kraig Ch4A142.7 Liu Ch28-291.2, Ch28-188.1 co:S Strober Ch28-289.1 co:S Strober Ch-H76~l, probes e,f, g, h Cory pAB:~-I 1 Bothwell Krawinkel pp.107 Matthyssens King MEP203 Maki Sakano M19, M28, M23, M2, M32 Marcu pjl4, M23, M2-20 Lang p~3741)9 + Marcu Brown (=pCp3741) Bosma + Seldin D'Eustachio pAB~-I, pAB~-8, ~s probe Alt pAB~-I, pABp.-8, pRI-Cg, Alt p~ probe, Igh-6/J genomie, Alt JH-Cgintron p r o b e , ~ probe Alt pRI-Cp., Igh-6/J genonde Aft pMKp.1 (=pMK-1) co:S Strober co:P Tucker XgtWES Igh701 Kataoka XgtWES.IgH701 co:T Honjo Ch28M.Igg-49, ChM.Igp.-18 Shimizu kgtWES.IgH701 Shimizu IgH701 + co:T Honjo pVECg co:N Maizels p]~183.5 Auffray pH76p.17, Ch-H76gl Gough pH76b~17 Adams pH76~17 Bernard Ch-H76p.119 co:D Kemp clone 5B6 Hilbert Co6J-17 Wood VMU-3.2,VGAM3-0,VMU-3.1,VMU-1 Winter pIge-7, Igh-7 genomie-1 eo:T Honjo pIge-7 + Shinkai pMEb-1, ~eb-9 Shinkai ChM Ige-12 Shimizu Ch30M.Ige-7, Ch30M.Ig~-6 Nishida Shimizu ChM.Ig~-12, Ch3OM.Iga-3 Shimizu C~Z30 Liu C230, IA7-SJL(E20) Gritzmacher L47-SJL(E20) Gritzmacher Gritzmaeher IgH701 co:T Honjo Igh-7 genomic-2 eo:N Orida MEP311, ME535, ME736 Roeder T7 Gerondakis CbM.Ig~-30 Kataoka " Shimizu Ch30 M Igy3-71 Takahashi

Refenmcde

tel:King, J Immunol 1990; 144:3218 Science 1980; 209:1353 ref:Owens Jr, Mol Cell Biol 1991; 11:5660 refiKnapp, PNAS 1982; 79:2996 refiKnapp, PNAS 1982; 79:2996 ref:Owens Jr, Mol Cell Biol 1991; 11:5660 Cell 1982; 28:499 Cell 1982; 28:499 Cell 1982; 28.'499 Cell 1982; 28:499 Cell 1982; 28:499 PNAS 1983 80:3030 Nattwe 1980; 283:733 Cell 1980; 19:981 Cell 1981; 27:573 Nature 1980; 283:733 Nature 1980, 284:452 Nature 1980; 284:452 J Exp Med 1983; 158:192 Science 1980; 209:1348 ref:Knapp, PNAS 1982; 79:2996 ref:Knapp, PNAS 1982; 79:2996 PNAS 1980; 77:4943 Cell 1981; 24.'625 PNAS 1983; 80:4997 Nucl Acid Res 1980; 8:703 J Immuno11990; 144:3218 PNAS 1980; 77:2138 Nature 1980; 286:676 Cell 1980; 22:187 Nucl Acid Res 1982; 10:611 Cell 1980; 22:187 Mol Cell Biol 1987; 7:450 Curr Top Microbiol Immunol 1988; 137:197 Genomics 1989; 5:24 J Exp Meal 1980; 151:1545 Cell 1980; 20:293 Mol Cell Biol 1982; 2:386 Cell 1980; 20:293 CelI 1980;20:293 Cell 1981; 27:381 ref:Knapp, PNAS 1982; 79:2996 ref:Owens Jr, Mol Cell Biol 1991; 11:5660 PNAS 1980; 77:919 ref:Takahashi, Gene 1980; 11:117 Cell 1982; 28:499 Cell 1982; 28:499 refiYaoita, Nature 1980; 286:850 ref:Boyle, Genomics 1992; 12:106 Gene 1980; 12:77 PNAS 1980; 77:554 Biochemistry 1980; 19:2711 PNAS 1980; 77:3630 ref:Bernard, PNAS 1980; 77:3630 J Immunol 1988; 140:4364 PNAS 1983 80.'3030 FAVIBOJ 1985;4:2861 ref:Ishida, EMBOJ 1982; 1:1117 Immunogenetics1988; 27:288 lmmunogenetics1988; 27:288 Nature 1981;289:149 PNAS 1981;78:1581 Cell 1982;28:499 Cell 1982;28:499 PNAS 1982;79:7852 J Immunol;1987 139:603 J Immuno]1987; 138:324 J Immunol1987; 139:603 ref:Gritzmaeher, J Immunol1987; 139:603 ref:Gritzmacher,J Immunol1987; 139:603 PNAS 1981;78:475 Immunogenet1991;34:392 PNAS 1980; 77:919 Cell 1982;28:499 ImmunoglobulinIdiotypes 1981;pp123 Continued on next p a g e

373

J.T. Eppig: Clones and Probes Table 3.

Continued.

Chr Sym~a

~

Name

12 Igh-8(~3)

immunoglobulin heavy chain, (C73)

12 Igh-D

immunoglobulin heavy chain, diversity

(DFL16) (DFL16.1)

(DFLI&I, DSP.I) (DSP-1, DFLI6.2, DSP-2)

(DsP-1) (DSP-1, DFLI6.2) (DsP-2)

(DSP-2.2) (DFL16.2, DSP-2, DSP-3) (DsP4, DSP-5, DSP-6) (DsP-6, DsP-7, DSP-8) (DSP-8, DSP-9) (DSP-8, DSP-9) (DSP-9) (DSP-9) (DSP-9) (DSP type segment) (DQ52)

Probeb

RFLVc Conia~l

Shimizu Ch M Ig"{3-32,Ch30 M Ig"{3-25 Takahashi Shimizu ChM.IgT13, ChM.Igy3-13 Shimizu pY5606T3.15 Adams Vf3/BgH2.5 Szurek + Mowatt pSi3 Brown SL14, SLS1, p~3-2.7 Long p~-6.0, SL13, SL15 Long VGAM3-2, VGAM3-8 Winter pG2a-10-21 Auffray Auffray pJH38Bg-7.1 Alt G5BB2.2, G S C A 1 . 7 Rocca-Serra G7AB2.9, G 8 A D 3 . 8 Rocca-Serra RBL216 co:RB Lang Igh-D10 eDNA, Igh-D20 eDNA Dzierzak B2, B49, B104, B38, D20 Early tffl/A5 Dunnick p40E4-2-P-5.2,RC-1, 3'D probe Alt pDJH22D6X, pDJH22D6Y Alt pVH22D6X', pVH22D6Y~ Alt pH76~17 Bernard pABg-ll, pAB~2a-1, pABT1-4 Bothwell pABg-11, pAB~2a-1 co:ALM Bothwell pV(ll)2, clone M141-P21 Bothwell 141p21 Maki M141-P21 co:H Sakano 17.2.25 co:D Weaver p129-48, p Y 1 9 - 1 0 Manheimer-Lery ME184-8 co:R Maki I23, IV92 co:M Fougereau pGAT50 Kraig clone 5B6 Hilbert I~119, A8.1 Kemp R-3, R-5, R-6, R-2 Wood KB5 ,KB6 Trepicchio Igh-D genomic + Trepicchio pl07V1, pl07aR5 Early pABwll Krawinkel (22 Yaoita pDhFL16-1 co:Riblett + co:Reth P6, $4, C5 Yaoita 5'DFL16 probe Alt pN25 co:M Wabl DI6-J2, RC-1, FL16D probe Kurosawa FL16D~ probe + Kuresawa pRN16, $36-2 Near RI-2, RI-4 Kurosawa RI-5, RI-6, RI-9 Kurosawa RIS1, RIS42, RIS46, RIS58 Kurosawa RIS14, RIS34, RIS35, RIS66 Kurosawa RIS52, RIS72 Kuresawa RIS64 Kuresawa DSP2.3 Alt C3H-2, SP2D probe Kurosawa C3H-2, SP2BI Kurosawa SP2DJ probe + Kurosawa 5'DSP2 probe Alt D probe, 5'Dprobe Blackwell VGAM3-0,VGAM3-2 Winter RIS3, RIS15, RIS29, RIS29 Kurosawa RP13, RP1 Kuroaawa RI-3 Kurosawa RIS43, RIS60 Kurosawa RIS79, B1-3 Kurosawa B1-3 Wood RIS40,RIS65,RIS25,RIS73 Kurosawa 1'2, $9 Yaoita RIS73 Wood RIS27,RIS67,RIS71,RIS74 Kurosawa B6BI Kurosawa

Refe~e~ee

Ceil 1982; 28:499 Immunoglobulin Idiotypes 1981; pp123 Cell 1982; 28:499 Cell 1982; 28:499 Biochemistry 1980; 19:2711 J Immtmol; 1985; 135:620 J Immunol 1986; 136:2674 Mol Cell Biol 1987; 7:450 Nucl Acid Res 1982; 10:611 Nucl Acid Res 1982; 10:611 EMBO J 198,5;4:2861 C,ene 1980; 12:77 Nucl Acid Res 1980; 8:1231 PNAS 1982; 79:4118 EMBO J 1983; 2:867 EMBO J 1983; 2:867 tel:Gilmore, J Immunel 1987; 139:619 J ExTMed 1985; 162:1494 Mol Cell BIol 1982; 2:829 Nucl Acid Res 1980; 8:1475 EMBO J 1984; 3:1209 EMBO J 1984; 3:1209 EMBO J 1984; 3:1209 PNAS 1980; 77:3630 Cell 1981; 24:625 ref:Kur~awa, J Exp Med 1983; 155:201 Cell 1981; 24.~25 PNAS 1980; 77:2138 ref:Kur~awa, J Exp Meal 1983; 155:201 refiBocTsch-Supan,J Exp Med 1985; 161:1272 PNAS 1986; 83.-8293 ref:Sakana, Nature 1981; 290:562 ref:Schiff, Nucl Acid Res 1983; 11:4007 J Exp Med 1983; 158:192 J Immtmo11988; 140:4364 J Mol Appl Genetics 1981; 1:245 PNAS 1983 80:.3030 J Immtmol 1985; 134:2734 J Immunol 1985; 134:2734 Cell 1980; 19.~981 PNAS 1983; 80:4997 Nucl Acid ires 1983; 11:7303 ref: Silver, JNCI 1986; 77:793 ref:Lehle, Etw J Immunol 1988; 18:1275 Nucl Acid Res 1983; 11:7303 EMBO J 1984; 3:1209 ref:Atkinson, J Immunol 1991; 146:2805 J Exp Med 1983; 155:201 J Exp Med 1983; 155:201 PNAS 1984; 81".2167 J Exp Med 1983; 155:201 J Exp Med 1983; 155:201 J Exp Med 1983; 155:201 J Exp Med 1983; 155:201 J Exp Med 1983; 155:201 J Exp Med 1983; 155:201 PNAS 1982; 79.'4118 J Exp Med 1983; 155:201 Nature 1981; 29~.565 Nature 1981; 290:565 EMBO J 1984; 3:1209 Cell 1984; 37:105 EMBO J 1985; 4.-2861 J Exp Med 1983; 155:201 J Exp Med 1983; 155:201 J Exp Med 1983; 155:201 J Ex-pMed 1983; 155".201 J Exp Med 1983; 155:201 PNAS 19838O:3030 J Exp Med 1983; 155:201 Nucl Acid Res 1983; 11:7303 PNAS 1983 80:3030 J Exp Med 1983; 155:201 Nature 1981; 290:565 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

374 Table 3. Continued. (~r Symhta

12

Igh-J

~

Name

immunoglobulin heavy chain, J region

(J1) (J1, J2) (J2) (J2) (J2) (J3) (J3) (J2,J3,J4) (J2, J3, J4) (J4) (J4) (J4)

Probeb

RFLVc Contactd

JH, pRLJH, pJH800 p40E4-2-P-5.2 pDJH22D6X, pDJH22D6Y pVH22D6X', pVH22D6Y' Igh-CP4 12-18 cDNA, pCP12

Alt Alt Alt Alt co:J-C Jaton co:J-C Jaton Igh-CP5 B5-3 cDNA co:J-C Jaton co:J-C Jaton Igh-CP5 A23-3 cDNA co:J-C Jaton Igh-CP5 A21-1 cDNA co:J-C Jaton Igh-CP4 9-9 cDNA co:J-C Jaton Igh-CP3 23-24 cDNA eo:J-C Jaton pRI-1.6, pRI-JH, Alt lgh-6/J genomic Alt JH Mucenski 33G7 + Sims pGW1 Atkinson p~l/A5 Dunnick JHSO0 (J4) co:F Alt SP2DJ probe Kurosawa 141p21,MEP203 M aki ME184-8 co:R Maki ME184-8, JH probe Blackwell J-H probe Blackwell 3' JH probe Near JH3,4 Dildrop J l l (J3,J4), M23 Marcu txIll co:CL Schildkraut co:C Berger pj0, pjll, RBL216 Lang RBL216 ho:RB Lang MRL-DNA4 Kofler pVMPCll, gtl0.Vll.19.3 co:BK Birshtein pV9.7.1-1, pvg.7.1/BE.9 co:BK Birshtein pVll.19.3, pV9.9.2.1 co:BK Birshtein Igh-ICRll.19.3, p J l l co:BK Birshtein ICR9.7.1, ICR9.9.2.1 ho:LA Eckhardt pAJ5 King King pH76}117 Gough pABp-11,pAB~2a-I,pAB71-4 Bothwell pV(ll)2, cone M141-P21 Bothwell pH76~17, ChSpp27 Bern ard Ch-H76g119 co:D Kemp VhNPb, VhARS, VhJ558 + Brodeur Vh7183, VhQUPC-52 + Brodeur pG2a-10-21 Auffray Auffray co:F Rougeon Ollo co:J-L Sikorav p(~556.3, pa48.16 Auffray pJH38Bg-7.1 Alt p6-1 eo:F Aft X2/3 fragment Gilles pGATS0, p27 Kraig pBR322-6.4JH co:F Alt 17.2.25 co:D Weaver Ep. Chen Gillies p129-48, pYIg-I0 Manheimer-Lory p~J558)13 co:K Marcu J probe co:ALM Bothwell pl07V1, pl07cd~5 Early pNN12 co:S Strober FL16D-J probe Kurosawa A8.1 Kemp pAB~I-11 Krawinkel pRN16, $36-2 Near P2, t~, 84, $9, C5 Yaoita DI6-J2 Kurosawa Ch28-289.1 co:S Strober Fgv21 Kronenberg C2 Yaoita KB5 ,KB6 Trepicchio

Befemencee

EMBO J 1984; 3:1209 EMBO J 1984; 3:1209 EMBO J 1984; 3:1209 EMBO J 1984; 3:1209 ref:Reininger, Eur J Immunol 1988; 18:1521 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, Eur J Immunol 1988; 18:1521 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 Cell 1981; 27:381 Cell 1981; 27:381 Mol Cell Biol 1986; 6:4236 Science 1982; 216:309 J Immunol 1991; 146:2805 Nuel Acid Res 1980; 8:1475 ref:Brown, Mol Cell Biol 1987; 7:450 Nature 1981; 290:565 PNAS 1980; 77:2138 refiSakano, Nature 1981; 290:562 Cell 1984; 37:105 Cell 1984; 37:105 PNAS 1984; 81:2167 Eur J Immunol 1987; 17:731 Cell 1980; 22:187 ref:Brown, Mol Cell Biol 1987; 7:450 refiVasmel, Leukemia 1987; 1:155 Nucl Acid Res 1982; 10:611 ref:Gflmore, J Immunol 1987; 139:619 J Immunol 1988; 140:4031 ref:Gilmore, J Immunol 1987; 139:619 ref:Gilmore, J Immunol 1987; 139:619 ref:Gflmore, J Immunol 1987; 139:619 ref:Gilmore, J Immunol 1987; 139:619 ref:Gilmore, J Immunol 1987; 139:619 PNAS 1989; 86.'2814 J Immunol 1990; 144:3218 PNAS 1980; 77:554 Cell 1981; 24:625 Cell 1981; 24:625 PNAS 1980; 77:3630 ref:Bernard, PNAS 1980; 77:3630 E u r J Immunol 1984; 14:922 Eur J Immunol 1984; 14:922 Gene 1980; 12:77 Nucl Acid Res 1980; 8:1231 ref:Ollo, Nucl Acid Res 1981; 9:4099 PNAS 1981; 78;2442 ref:Sikorav, Nucl Acid Rea 1980; 8:3143 Gene 1981; 13:365 PNAS 1982; 79:4118 ref:Brown, Mol Cell Biol 1987; 7:450 Cell 1983; 33:717 J E~p Med 1983; 158:192 ref:Boersch-Supan, J Exp Med 1985; 161:1272 ref:Boersch-Supan, J Exp Med 1985; 161:1272 Cell 1987; 51:7 Cell 1983; 33:717 PNAS 1986; 83:8293 ref:Tueker, PNAS 1981; 78:7684 ref:Krawinkel, PNAS 1983; 80:4997 Cell 1980; 19:981 ref:Knapp, PNAS 1982; 79:2996 J F,xp Med 1983; 15~:201 J Mol Appl Genetics 1981; 1:245 PNAS 1983; 80:4997 PNAS 1984; 81:2167 Nuel Acid Res 1983; 11:7303 J Exp Meal 1983; 155:201 ref:Knapp, PNAS 1982; 79:2996 J Exp Med 1983; 158:210 Nuci Acid Res 1983; 11:7303 J Immunol 1985; 134:2734 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

375

Table 3. Continued. Chr Symbola

12

Igh-V

b~cusName

immunoglobulin heavy chain, variable

12

Igh-Vl0

(BALB) Igh-variable ( e l 0 family)

12

Igh-Vll

Igh-variable (Vll family)

Probeb

RFLVr Contactd

pTI/A5

Dunnick

MMIGVH16 (microsat) + co~IA Todd " (micrcaat) + coMA Todd MMIGVH28 (microsat) + co'JA Todd (microsat) + co'JA Todd pM173~a.20, pHIy2a.17 Adams pM603a.8 Adams pGATS0 Kraig clone 27 Hartman done 5B6 Hilbert Ch.IgVH101-A, Ch.IgVH101-B co:T Honjo ~.VAR1, ~.VAR2, XVAR3 Krawinkel ~.VAR4, LVARS, XVAR6 Krawinkel ~.VAR7, pABII-11 Krawinkel V probe, leader region probe co:ALM Bothwell pV186.2, ;~V102 co:ALM Bothwell C2, C5 Yaoita KB5 ,KB6 + Trepicehio Igh-V genomic Liu MRL-DNA4 + Kofler " + Meek MRL-RF24B Kofler 0401-13, 0401-4, 0401-3 co:EW Voss J r 040143, 040142 co:EW Voss J r pCP12 + Reininger + Meek Igh-CP4 12-18 cDNA, pCP12 co:J-C Jaton " Igh-CP5 B5-3 c D N A Igh-CP5 Igh-CP5 Igh-CP4 Igh-CP3

co:J-C Jaton co:J-C Jaton co:J-C Jaton co:J-C Jaton co:J-C Jaton co:J-C Jaton co:J-C Jaton

A23-3 c D N A A21-1 c D N A 9-9 c D N A 23-24 c D N A

12

Igh-VGAM3-8 Igh-variable (GAM3-8 family)

VGAM3-8

12 12

Igh-VSM7 Igh-variable (SM7 family) Igh-VQ52 Igh-variable (Q52 family)

VMU-1 pVhSM7 300.19 VHQ52 VhQUPC-52

+ + +

+ + + + + + +

pVhQ52 pVhQ52N ChM.IgT1-704, ChM.lgT1-706, plgT1-706-1 Ch.IgVH101-A plgVH101-10 + VhOXAZOLONE VhMOPC-141 M141-P21

12

Igh-VS107 Igh-variable (S107 family)

" 141p21 clone H1, clone H2 $9 S107 VhS107

+

+ + + + + 7~V1 S107B, S 107B-gerraline pl07V1 + + pl07V1, ~.Vll pS107ct4 Ch603a6, pl07aRS, pl07aR6

Winter co:E Winter co:Blankenstein Winter Tutter Yancopoulos Blankenstein co:Blankenstein co:M Shapiro co:M Shapiro Eicher co:PH Brodeur co:T Honjo co:T Honjo co:T Honjo co:T Honjo Brodeur co:Kelly-Siebenlist Sakano Bothwell co:T Honjo Maki Deyev Yaoita Perlmutter co:R Riblet Marcu Blankenstein Tutter co:Blankenstein co:G Yancopoulos Kofler Bailey Kofler Kwan Early co:L Hood co:P Early Kronenberg co: JA Griffin Adams Early

Refememee

Nucl Acid Res 1980; 8:1475 ret~Hearne, M a m m Genome 1991; 1:273 refiMontagutelli, M a m m Genome 1991; 1:255 ref:Hearne, Marnm Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 Biochemistry 1980; 19:2711 Biochemistry 1980; 19:2711 J Exp Med 1983; 158:19"2 EMBO J 1984; 3"~3023 J Immuno11988; 140:4364 ref:Kataoka, J Biol Chem 1982; 257:277 PNAS 1983; 80:4997 PNAS 1983; 80.'4997 PNAS 1983; 80:4997 ref:Krawinkel, PNAS 1983; 8014997 ref:Krawinkel, PNAS 1983; 80:4997 Nucl Acid Res 1983; 11:7303 J Immuno11985; 134:2734 Nucl Acid Res 1987; 15:6296 J Immunol 1988; 140:4031 Molec Immunol 1990; 27:1073 J Immtmol 1988; 140:4031 ref:Chao, Mol Immunol 1992; 29:439 ref:Chao, Mol Immunol 1992; 29:439 Eur J Immuno11988; 18:1521 Molec Immtmol 1990; 27:1073 ref:Reininger, Eur J Immunol 1988; 18:1521 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, Eur J Irnmunol 1988; 1811521 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Irnmunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 EMBO J 1985; 4"2861 ref:Blankenstein, Eur J Immun 1987; 17:1351 ref:Lehle, Eur J Immtmol 1988; 18:1275 EMBO J 1985; 4:2861 J Immtmol 1991; 147:3215 Nature 1984; 311:727 E u r J Immunol 1987; 1711351 ref:Lehle, Eur J Immunol 1988; 18:1275 ref:Brodeur, Eur J Immtmol 1984; 14:922 re.f.'Kofler, J Exp Med 1985; 162:346 Genetics 1990; 125:431 ref:Tutter, Immunogenetics 1988; 28:125 ref.'Kataoka, J Biol Chem 1982; 257:277 ref:Kataoka, J Biol Chem 1982; 257:277 ref:Kataoka, J Biol Chem 1982; 257:277 refiKataoka, J Biol Chem 1982; 257:277 Eur J Immunol 1984; 14,022 ref:Brodeur, Eur J Irnmunol 1984; 14:922 Nature 1980, 286:676 Cell 1981; 24:625 ref.'Kataoka, J Biol Chem 1982; 257:277 PNAS 1980; 77:2138 Genetica 1991; 85:45 Nucl Acid Res 1983; 11:7303 Adv Immtmol 1984; 35:1 ref:Brodeur, Eur J Immunol 1984; 14:922 Cell 1980 22:187 Eur J Immunnl 1987; 17:1351 Immunogenetics 1988; 28:125 ref:Lehle, Eur J Immunol 1988; :[8:1275 ref:Atkinson, J Immunol 1991; 146:2805 J Immunol 1988; 140:4031 E u r J Immunel 1991; 21,O59 J Immunol 1988; 140:4031 Cell 1981; 26:57 Cell 1980; 19:981 ref:Hilbert, J Immunol 1988; 140:4364 ref:Kofler, J Exp Meal 1985; 162:346 J Exp Meal 1983; 158:210 ref:Kraig, J Exp Med 1983; 158:192 Biochemistry 1980; 19:2711 PNAS 1979; 76:857 Continued on next page

].T. Eppig: Clones and Probes

376 Table 3. Continued. Chr b - ~

a

Locus Name

12

Igh-VSl07

lgh-variable (S107 family)

12

Igh-VX24

Igh-variable (X24 family)

12

Igh-V31

Igh-variable (V31 family)

12

Igh-VJ558

Igh-variable (J558 family)

Probeb

RFLVc Conlactd

CHSpVH3, CH603a6 CH603a125 Ch603a6 ChSpVpc3, Ch603a6, Ch603a125, p107o2~5 ChM 167a10,ChM603a6,kV 1 B2 Vh38C +

D avis D avis Bothwell Early Early Kim Early Nelson co:K Nelson Vh6G6 + Clarke co:S Clarke kV3207.1,kV603.1,pS107VI eo:P Early kVl co:F Rougeon ~VI, kV3, kV10, kV11, Crews kVl3, kV19 Crews M31 Kemp VH39, VH39.1, VH55, VH55.1 Hartman VHGal probe Hartman VhGa139.1 co:Hartman VhX24, pL7 + co:Hartman " + Tutter pVHXRPC24 + co:GE Wu, CJ Paige VH55.1 + Hartman pG2a-10-21 Auffray Auffray Ollo co:J-L Sikorav Charon4A VH283 co:F Rougeon p325-VH441-IV, p325-VH283 co:F Reugeon pa48.16 Auffray Charon4A441, pG2a-lO-21 co:F Rougeon pVH441-3, pVH441-4 co:F Rougeon VH441-4 + Blankenstein Vh-24X genomic Arepalli V31 Winter + co:E Winter § co:Blankenstein VMU3.1 + Winter ~.I-8-7, ~1-8-18 Blankenstein VMU-3.1 + Winter pY19-10 Manheimer-Lory ~.1-8-7, ~.1-8-18 Blankenstein kVNPB-186 + Blankenstein IGELb4 Kofler clones A1, A4, AS, B4 Yancopoulous V.B4 probe, 5'F.B4 probe Yancopoulous 3'F.A1 probe Yancopoulous pV.A1 Pst (clone A1) Schuler kFla, pVId-3665, pVi220 Siekevitz pVR130 + Siekevitz kIDCR2, kIdCR24, co:ML Gefter kldCR10, kIdCRll co:ML Gefter V probe, kIdCR7, %IdCR17 co:ML Gefter kIDCR1, ~.IdCR14 co:ML Gefter PJ14 Sakano I23 eo:M Fougereau Igh-17.2.25 co:D Baltimore IV92 + co:M Fougereau G5BB2.2, GSCA1.7 Rocca-Serra G7AB2.9, G8AD3.8 Rocca-Serra 9~G7 + Sims 93G7, VHA probe Rathbun clones91A3, 1.8,186, 1.3 Rathbun clones15, 21, 43, 83, 28, 122 Rathbun CDR-1 probe, VH186 genomie Rathbun VH21 genomic, CDR-2 probe + Rathbun V H 4 3 Y genomic, + Rathbun V H 2 8 genomic + Rathbun VHI22T genomic + Rathbun ~FVH122B genomic + Rathbun F9V21 Kraig J558VH Livant VhJ558 + co:C Mallet + co:Brodeur + co:Brodeur p~J558)13 co:K Mareu

Nature 1980, 283:733 Nature 1980; 283:733 Cell 1981; 24:625 Cell 1980; 19.981 Cell 1980; 19.-981 Cell 1981; 27:573 Mol Cell Blol 1982; 2:829 Mol Cell Biol 1983; 3:1317 ref: Brodeur, Eur J Immunol 1984; 14:92 J Exp Med 1984; 159:773 ref: Brodeur, Eur J Immunol 1984; 14:92 tel:Crews, Cell 1981; 25:59 ref:Ollo, Nuel Acid ires 1983; 11:7887 Cell 1981; 25:59 Cell 1981; 25:59 J MoI Appl Genetics 1981; 1:245 EMBO J 1984; 3:3023 EMBO J 1984; 3:3023 ref:Bonilla, J Immunol 1990; 145:616 ref:Brodeur, Eur J Immunol 1984; 14:922 Immunogenet 1988; 28:125 ref:Reininger, Eur J Immunal 1988; 18:1521 J Exp Meal 1985; 162:346 Nucl Acid Ras 1980; 8:1231 Gene 1980; 12:77 PNAS 1981; 78;2442 ref:Sikorav, Nucl Acid IRes 1980; 8:3143 refiOllo, Nuel Acid Res 1983; 11:7887 refiOllo, Nucl Acid IRes 1983; 11:7887 Gene 1981; 13:365 ref:Ollo, Nucl Acid Res 1981; 9:4099 ref:Ollo, Nucl Acid Res 1981; 9:4099 Eur J Immunol 1987; 17:1351 Nucl Acis Red 1990; 18:7152 EMBO J 1985; 4:2861 ref:Blankenstein, Eur J Immun 1987, 17:1351 ref:Lehle, Eur J Immunol 1988; 18:1275 F_~MBOJ 1985; 4:2861 E u r J Immunol 1987; 17:1351 EMBO J 1985; 4:2861 PNAS 1986; 83:8293 E u r J Immunel 1987; 17:1351 E u r J Immunol 1987; 17:1351 Mol Immunol 1992; 29:161 Cell 1985; 40:271 Cell 1985; 40:271 Cell 1985; 40:271 EMBO J 1988; 7:2019 Eur J Immunol 1982; 12:1023 Eur J Immunol 1982; 12:1023 ref:Siekevitz, Eur J Immunol 1983; 13:123 ref:Siekevitz, Eur J Immunol 1983; 13:123 ref:Siekevitz, Eur J Immunol 1983; 13:123 ref:Siekevitz, Eur J Immunol 1983; 13:123 Nature 1980; 286:676 ref:Schiff, N u d Acid Res 1983; 11:4007 ref:Schiff, Nucl Acid Res 1983; 11:4007 reflSehiff, Nucl Acid Res 1983; 11:4007 EMBO J 1983; 2:867 EMBO J 1983; 2:867 Science 1982; 216:309 J Mol Biol 1988; 202:383 J Mol Biol 1988; 202:383 J Mol Biol 1988; 202:383 J Mol Biol 1988; 202:383 J Mol Biol 1988; 202:383 J Mol Biol 1988; 202:383 J Mol Biol 1988; 202:383 J Mol Biol 1988; 202:383 J Mol Biol 1988; 202:383 J Exp Med 1983; 158:192 Cell 1986; 47:461 ref:Brodeur, Eur J Immunol 1984; 14:922 ref:Kofler, J Exp Med 1985; 162:346 Tutter, Immtmogenet 1988; 28:125 tel:Tucker, PNAS 1981; 78:7684 C o n t i n u e d on next page

377

J.T. Eppig: Clones and Probes Table 3.

Continued.

Chr Sym}~a

LocusName

12 Igh-VJ558 Igh-variable (J558 family)

12

(from A/J) (from BALB/c, VhldCR-related) Igh-VJ606 Igh-variable (J606 family)

12 Igh-V3609 Igh-variable(3609P family)

Prd~

RFLVc Cmt~-td

pa658.3 Auffray P9.37.1, 18.1.16, P1O.15.1 Boerseh-Supan P4.16.25, P3.6.5, P5.40.1 Boerseh-Supan 20.1.43, P4.5.1, XVNPB-130 Boersch-Supan 17.2.25 co:D Weaver XVNPB-1,XVNPB-2,~NNPB-4 Bothwell XVNPB-5).VNPB-12,XVNPB-16 Bothwell kVNPB-17,XVNPB-20,kVNPB*22 Bothwell %VNPB-3,~.VNPB-147,LVNPB-104 Bothwell XVNPB-6,~.VNPB-130,XVNPB- 102 Bothwell ~NNPB-145,kVNPB-168,%VNPB-23 Bothwell XVNPB-186 (=V186) Bothwell + Blankenstein pABW11,pAB~a- 1,pABT1-4 Bothwell pVT2a-1, pV104.S(5.0)-I Bothwell pV102.R(5.5+2.0)-l, pV(ll)2 Bothwell pV102.R(5.0)-I,pV186.R(5.0)-I Bothwell pV186.R(5.0)-2, pV3.PJR(4.0)-I Bothwell pV147.R/S(0.6)-l,pV104.S(3.0)-1 Bothwell VhDx11 co:P Early pV(ll)2, Chll 1, Chl08 Givol Chl04, pChl08A, pChl08B Givol pChlll, pCh104 Givol pV(ll)2, pChl05, pCh111 Cohen pChl04, pChl08A,pChl08B Cohen pCh108,Ch104,Ch105, Ch111 Cohen Ch9.9.2.1, Ch9.7.1 eo:BK Birshtein RBL216 eo:RB Lang pVMPCll, gt10.Vll.19.3 co:BK Birshtein pV9.7.1-1, pV9.7.1/BE.9 co:BKBirshtein pVll.19.3, pV9.9.2.1 ho:BK Birshtein Igh-ICRll.19.3 ho:BK Birshtein ICRg.7.1, ICR9.9.2.1 ho:LA Eckhardt VhT1035 Brodeur VhHEL-3F4, VhS11TN Brodeur VhARS + Sims eo:J Sims pv(ll)2, M23 Lang VhMPC-11 (=pv(11)2] ce:R Lang VhT0Z + Nelson co:KJ Nelson VAR104, VAR34 + Blankenstein VAR100, chl04 Blankenstein pV(11)1, pV(11)2 Zakut VMU-3.2, VGAM3-0 Winter pChl05, pV186.R(5.0)-2 Winter VhIdCR genomic + Wysocki VhIdCR-related genomic + Wysocki VhJ606 + eo:S Crews + Blankenstein + co:Blankenstein + Kofler co:S Crew DB1-310.9 Kofler Ch-H76g119, probe a Cory pH76p.17 Adams VH76CH119 co:O Bernard pH761~I7 Bothwell Bern ard co:F Rougeon Gough Ch-H76gl19 eo:D Kemp VH22, VH22.1 Hartman V14B eo:S Crew V14A probe eo:S Crew pBV14RB7 Wa n g " Tutter M109, M97, MS1,M110, Kemp M59, Mll, M98, M48 Kemp ~tl19, A8.1 Kemp probe e, Igh-VhJ606 eo:O Bernard pVh3635 + co:Brodeur VH3609P Riblet 1-D'Eustachio co:R Riblet

Refwaneee

Gene 1981; 13:365 J Exp Med 1985; 161:1272 J Exp Med 1985; 161:1272 J Exp Med 1985; 161:1272 ref:Boersch-Supan,J Exp Meal 1985; 161:1272 in:The Biologyof Idiotypes 1984, p 19-34 in:The Biologyofldiotypes 1984, p 19-34 in:The Biology ofldiotypes 1984, p 19-34 Cell 1981;24.625 Cell 1981; 24.'625 Cell 1981; 24:625 Cell 1981; 24.625 Immunogenetics 1987; 26:2:37 Cell 1981; 24.625 Cell 1981; 24.'625 Cell 1981; 24.625 Cell 1981; 24.625 Cell 1981; 24.625 Cell 1981; 24:625 ref:Brodeur, Eur J Immunol 1984; 14:922 Nature 1981; 292:426 Nature 1981; 292:426 Nature 1981; 292:426 Nucl Acid Res 1982; 10:3353 Nucl Acid ires 1982; 10:3353 Nucl Acid Res 1982; 10:3353 ref:Eckhardt, Mol Cell Bid 1985; 5:856 ref:Gilmore, J Immunol 1987; 139:619 ref:Gilmore, J Immunol 1987; 139:619 ref:Gilmore, J Immtmol 1987; 139:819 ref:Gilmore, J Immunol 1987; 139:619 ref:Gilmore, J Immunol 1987; 139:619 refiGilmore, J Immunol 1987; 139:619 Eur J Immunol 1984; 14~22 EurJ Immunoi 1984; 14:922 Science 1982; 216:309 ref: Brodeur, Eur J Immtmo][ 1984; 14:92 Nucl Acid Res 1982; 10:611 ref: Brodeur, Eur J Immuno][ 1984; 14:92 Mol Cell Biol 1983; 3:1317 re['.. Brodeur, Eur J Immuno][ 1984; 14:92 Immunogenetics 1987; 26:23.7 Immunogenetics 1987; 26:237 Nucl Acid Res 1980; 8:3591 EMBO J 1985; 4:2861 F_,MBOJ 1985; 4:2861 Molec Immunol 1989; 26:1143 MoIec Immunol 1989; 26:1143 ref:Brodeur, EurJ Immunel 1984; 14:922 EurJ Irnmunol 1987; 17:1351 ref:Lehle, Eur J Immunel 1988; 18:1275 J Immunol 1988; 140:4031 ref:Kofler, J Exp Med 1985; 162:346 J Immunol 1988; 140:4031 PNAS 1980; 77:4943 Biochemistry 1980; 19:2711 ref.'Epstein, J Irnrnunol 1989; 142:1596 Cell 1981; 24.625 PNAS 1980; 77:3630 ref:Ollo, Nucl Acid Res 1983; 11:7887 PNAS 1980; 77:554 ref:Bernard, PNAS 1980; 77:3630 EMBO J 1984; 3:3023 ref.-Kronenberg,J Exp Med lO83; 158:210 ref:Kraig, J Exp Med 1983; 158:192 Cell 1985; 43:659 Irnmunogenetics 1088; 28:125 J Mol Appl Genetics 1981; 1:2,15 J Mol Appl Genetics 1981; 1:2,15 J Mol Appl Genetics 1981; 1:245 ref:Gough, PNAS 1981; 78:509 ref:Tutter, Immunogenetics 1988; 28:125 In:Genetics and Molecular Immunology 1986 (ed. Herzenberg et al) PNAS 1989; 86:5035 ref:Cho, Mamm Cenome 1991; 1:30 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

378 Table 3. Continued. Chr Symbda

Locus Name

12 12

Igh-V3609N Igh-variable 3609N non-productive Igh-V3660 Igh-variable (3660 family)

12

Igh-V7183

Igh-variable (7183 family)

12

"Igh-en"

Igh enhancer

12

iv

situs inversus viscerum

12

Lambl-1

(transgene) ]aminin B1, subunit 1

12 12

lgl Ltrm- 1

12 12

Mmv-18 "Mns-12"

12

Mpmv- 11

12 12 12

legless transgene mutation (see iv) LTR mink cell focus-forming murine leukemia viral locus-1 MCF endogenous virus-18 minor satellite Chr 12 (centromeric)

Probeb

P~LVc C ~ a t ~

pVH3609N 460-42, D35-10, LBS-3, Igh-2AB5 eDNA, Igh-ID29 eDNA, Igh-ID16 eDNA, Igh-ID30 eDNA, Igh-M315 eDNA, 460-42,D35-10,LB8-3,SB-2.1 Igh-M315 eDNA IGELa2 pRNI6, SB-104, SA-5.1 SA-31, SB-83,SB-2.1,SB36-2 Vh36-60probe + Vh36-60 + SB32 pRN5.15 + + VGAM3-2, SB-2.1 VGAM3-2 + + lgh-Vh3660 probe + p129-48 Vh7183 + pVhSA~-15 +

Ref~mcee

Tutter Dzierzak Dzierzak Dzierzak Dzierzak Dzierzak Dzierzak Dzierzak Dzierzak Kofler Near Near Near co:R Near co:R Near Weiss Tutter Winter co:E Winter co:Blankenstein co:S Riley Manheimer-Lory co:C Coleclough Brodeur co:Brodeur co: Riblet + co:GE Wu, CJ Paige VH81X/VHE4.Psi genomic Yancopoulos VH81X genomic Yancopoulos Manheimer-Lory + Blankenstein VH283 Hartman VH37, VH37.1, VHS0, VH50.1 Hartman Vh37 Kastner VH37.1 M a nheimer- Lory Vh37-77 co:S Clarke Vh37-65N co:S Clarke pVH22D6X', VHI-7 probe Yancopoulos pABTI-4 , pVH-81X Yancopoulos 40E4-2-26-8.0, 40E4-2-15-3.0 Yancopoulos 40E4-2-5-2.0, 40E4-2-16-2.0 Desiderio 49E4-2-15-3.0, 40E4-2-26-8.0 Desiderio 22D6-G-1-2.1, 22Dt-G-2-3.5 Desiderio Fgv21 Kronenberg ).VH-81X, pVH-81X, Alt probe VH-81X Al t pVH-81X, kVH-81X A]t pVH22D6Y', pVH22DtX' Alt VDJ3-1 co:G Yancopoulos VhMoPC-21 co:E Craig p62H3 Sequeira F9V21 Kronenberg + co:Kronenberg 3'a-1.3 Stavnezer 3"a-1.3, 3'a-0.7 co:J Stavne~er kM2, )~M3 co:MS Neuberger Jla, Jlb, J2 + co:SS Potter C-10m, C-11 co:SS Potter pHT1 co:SS Potter pPF.386, pPFA9 Elliot pPE386 + co:RW Elliott p24, :LBI-II Sasaki

J Immunol 1991; 147:3215 J Exp Med 1985; 162:1494 J Exp Med 1985; 162:1494 J Exp Med 1985; 162:1494 J Exp Med 1985; 162:1494 J Exp Med 1985; 162:1494 J Exp Med 1985; 162:1494 J Immunol 1986; 136:1864 J Immunol 1986; 136:1864 Mol Immunol 1992; 29:161 PNAS 1984; 81:2167 PNAS 1984; 81:2167 PNAS 1984; 81:2167 ref:Bredeur, Eur J Immunol 1984; 14:922 ref:Dzierzak, J Immunol 1986; 136:1864 J Immunogenet 1989; 16:283 Immunogenetics 1988; 28:125 EMBO J 1985; 4:2861 ref:Blankenstein,Eur J Immunol 1987; 17:13 ref:Lehle, Eur J Immunol 1988; 18:1275 ref:KofleL J Exp Med 1985; 162:346 P N A S 1986; 83:8293 ref:Brodeur, EurJ Immunol 1984; 14:922 Eur J Immunol 1984; 14~22 ref:Tutter, Immunogenetics 1988; 28:125 ref:Atkinson, J Immunol 1991; 146:2805 ref:Reininger, Eur J Immunol 1988; 18:1521 Nature 1984; 311:727 Nature 1984; 311:727 P N A S 1986; 83:829,3 Eur J Immunol 1987; 17:1351 E M B O J 1984; 3:3023 E M B O J 1984; 3:3023 J Immunol 1989; 143:2761 P N A S 1986; 83:8293 re~.Bredeur, Eur J lmmunol 1984; 14:922 ref:Brodeur, Eur J Immunol 1984; 14:922 Nature 1984; 311:727 Nature 1984; 311:727 Nature 1984; 311:727 Nature 1984; 311:752 Nature 1984; 311:752 Nature 1984; 311:752 J Exp Med 1983; 158210 Nature 1982; 296:325 Nature 1982; 296:325 Cell 1980; 20:293 FAVIBOJ 1984; 3:1209 ref:Brodeur, Eur J Immunol 1984; 14:922 ref:Brodeur, Eur J Immunol 1984; 14:922 Mol Immunol 1992; 29:425 J Exp Med 1983; 158:210 ref:Kofler, J Exp Med 1985; 162:346 Nucl Acid Ree 1986; 14:6t29 ref:Lieberson, Nucl Acid Rcs 1991; 19:933 ref:Dariavach, Eur J Immunol 1991; 21:1499 ref:Singh, Genes & Devel 1991; 5:2245 ref:Singh, Genes & Devel 1991; 5:2245 ref:Singh, Genes & Devel 1991; 5:2245 In Vitro Cell Dev Bio 1985; 21:477 ref:Seldin, Genomics 1989; 5:24 PNAS 1987; 84~35

CI-3-LTR

J Viral 1983; 44]:740 Genetics 1990; 125:431 Mamm Genome 1992; 2:110 Nucl Acid Res 1983; 11:8847 ref:Breecoli, Cytogenet Cell Genet 1990; 54:18 ref:Pietraa, Nucl Acid Res 1983; 11:6965 Genetics 1990; 124:221 ref:Geratein, Cell 1990; 63:537 Mamm Genome 1992; 2:110 Genetics 1990; 124:221 ref:Blatt, PNAS 1983; 80:6298 PNAS 1990; 87:4585 PNAS 1990; 87:4585

MCFIO0 pMR150

modified polytropic murine leukemia v i r a s - l l JS-4 JH JS-4 Mpmv-24 modified polytropic murine leukemia virus-24 JS-4 pMo~MCFI-16 ~Ms I-2-14-P2" minisatellite I~ (=Drcsophila Per) pSP.2.5.EI ~r 1-3-8-P2" minisatellite 1-3-8-P2(=Drosophila Per) pSP.2.5.EI

+ +

+ + + + + + +

Rapp Eicher Frankel Voliva co:VM Chapman co:ND Hastie Frankel co:W Frankel Frankel Frankel co:M Vogt Julier Julier

Continued on next pa~

J.T. Eppig: Clones and Probes Table 3.

Continued.

Chr Symbda

12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12 12

379

Locus Name

~Ms2-2-12-P2" minisatellite2-2-12-P2 (human DIS57) 'WIs2-1-6-Pl" minisate]lite2-1-6-P1 (human DIS57) '~Ms2-1-7-P2" minisatellite2-1-7-P2 (human D1S57) '~VIs2-2-13-PI" minisatellite2-2-13-Pl (human D1S57) "Ms2-3-11-PI" minisatellite2-3-11-P1 (human DIS57) 'WIs2-3-24-P2" minisatellite2-3-24-P2 (human DIS57) 'TIs2-3-7-P2" minisatellite2-3-7-P2 (human D1S57) 'WIs4-3-15-P2" minisatellite4-3-15-P2 (human D2S44) "Ms5-2-13-P2" minisatellite 5-2-13-P2 '2VIs7-1-1-P2" minisatellite7-1-1-P2 (human RBI) 'WIs7-2-11-P2" minisatellite7-2-11-P2 (human RB1) '~Ms7-3-10-P2" minisatellite7-3-10-P2 (human RB1) 'WIs7-2-2-PI" minisatellite 7-2-2-P1 (human RB1) '~VIs7-3-5-Pl" minisatellite 7-3-5-P1 (human RB1) '2Vls7-2-7-Pl" minisatellite 7-2-7-P1 (human RB1) 'WIs7-3-1-PI" minisatellite 7-3-1-P1 (human RB1) '2VIs8-2-3-P2" minisatellite 8-2-3-P2 (human INS) '2VIs8-3-5-P2" minisatellite 8-3-5-P2 (human INS) Mtv-9 m a m m a r y tumor virus locus-9

12 Mtv-30 12 Mylf-ps

m a m m a r y tumor virus locus-30 myosin light chain, alkali, fast skeletal muscle, pseudogene

12

"Nkx-2.1" homolog of Drosophila NK-2

12

Nmyc-1

neuroblastoma myc-related oncogene-1

Probeb

RFLVc Conta~

pYNZ2 + pYNZ2 + pYNZ2 + pYNZ2 + pYNZ2 + pYNZ2 + pYNZ2 + pYNH24 + pEWRB2.3 + p68RS2.0 + p68RS2.0 + p68RS2.0 + p68RS2.0 + p88RS2.0 + p68tKS2.0 + p68RS2.0 + pINS310 + pINS310 + clones A1, A2, A3, A4 clones A8, A13, 3U, E2, E4 pSC34 (MMTV env) Mtv9-3'C + + Mtv9-5'C + + Mtv9-5', Mtv9-3' Mtv-9 probe + MMTV eDNA + MTV-LTR + ev-8, pvc-28 + MMTV8-21,MMTV8-29 M M T V 8-21 + M M T V 8-29 + MMTV8-21,MMTVS-29 + M M T V env probe + pTZ18R-ORF + MMTV8-21,MMTV8-29 + pG~AS0 pGLC450, Mylf-ps genomic p161, Type A r Type B r Type C r [R] TTF-I genomie probe Nk-2.1 genomic pLM1 clone91 pN7.7 p277.3

pM.2

12

Ode

ornithine decarboxylase structural gene

Ode flanking 5' 12

Odc~rs8

ornithine decarboxylase related seq-8

12

Pmv-3

polytropic murine leukemia virus-3

12 12 12

Pmv-27 Pmv-37 Pol-7

polytropic murine leukemia virus-27 polytropic murine leukemia virus-37 viral polymerase gene-7

Nmyc-1 eDNA Nmyc- 1 probe + kT28 [H] p0 (exon 2) MMMYCNA (microsat) + pOD100, pOD1, pOD12.7 pOD100 pOD12.7 pCR6 (pDOC934 derived) + mODC-gl pODC100, pODCC~0 + pODC650 + + pmODC-1 Ode e D N A pODC54, pODC16, pODC74 Ode genomic MMODCC (microsat) + pOD48 + pOD48, pOD32 JS-5 + JS-5, MCF100 + JS-5 + JS-5 + B65.5PV2 derivative +

Ref~e~cee

Julier PNAS 1990; 87:4585 PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Julier PNAS 1990; 87:4585 Juliet co:T Dryja rePJulier, PNAS 1990; 87:4585 ref'Julier, PNAS 1990; 87:4585 eo:T Dryja ref'Julier, PNAS 1990; 87:4585 co:T Dryja ref:Julier, PNAS 1990; 87:4585 co:T Dryja co:T Dryja ret~Julier,P N A S 1990; 87:4585 tel:Juliet,P N A S 1990; 87:4585 co:T Dryja co:T Dryja ref:Julier, P N A S 1990; 87:4585 ref:Julier,P N A S 1990; 87:4~585 eo:G Bell ref:Julier,P N A S 1990; 87:4585 co:G Bell King J Immuno11990; 144:3218 J Immunol 1990; 144:3218 King J Immunol 1988; 141:2510 Sharma J Virol 1986; 59:535 Peters ref:Dyson, Nature 1991; 349:531 co:G Peters J Virol 1986; 59:535 Peters tel:Blank, Genetics 1988; 120:1073 co:G Peters J Virol 1986; 59:535 Peters ref:Knight, Mol Cell Probes 1990; 4:497 co:Peters Virology 1985; 142;278 Michalides Virology 1985; 142;278 Michalides ref:Moen, M a m m Genome 1991; 1:217 co:Michalides Nature 1981; 289:253 Majors Genetics 1990; 125:431 Eicher Genetics 1990; 125:431 Eicher refiLee, J Virol 1990; 64:4568 co:EM Eicher Immunogenet 1987; 25:222 Yang ref:Puilen, J Exp Med 1992; 175:41 co:JE Majors ref.'Lee, J Virol 1990; 64:4568 co:EM Eicher J Biol Chem 1985; 260:8578 Barton Cell 1984; 39:129 + Robert Cell 1984; 39:129 Robert Cell 1984; 39:129 Robert EMBO J 1990; 9:3631 Guazzi Neuron 1992; 8:241 Price personal communication co:Y Taya EMBO J 1986; 5:1215 Taya PNAS 1985; 82:5455 Yancopoulos rof:DePinho, PNAS 1986; 83:1827 co:FW Aft PNAS 1986; 83:1827 DePinho Mouse Genome 1991; 89:275 Klett Nature 1986; 31~.780 Zimmerman rof:Campbell, Oncogene 1Res 1989; 4:47 eo:P D'Eustachio ref:Katoh, Nucl Acid Res 1988; 16:3589 co:H Kondoh eo:B Stanton,L Parada ref:Oettinger, Genomics 1991; 11:334 EMBO J 1989;, 8:133 vanLohuizen ref:Ingvarsson, Oncogene 1988; 3:679 co:Kohl ref:Hearne, M a m m Genome 1991; 1:273 co:JA Todd PNAS 1988; 85:2200 Brabant Cytogenet Cell C.enet 1988; 48:92 Cox Nucl Acid Res 1988; 16:2731 Coffino Mol Endocrinol 1989; 3:1243 Rheaume rel2Siraeuaa, Genetics 1991; 127:169 co:FG Berger J Biol Chem 1988; 263:7604 Katz GenomJcs 1989; 5:636 Villani Genomics 1991; 9:778 Davisson ref:Frankel, M a m m Genome 1992; 2:110 co:P D'Eustachio PNAS 1985; 82:1673 Kahana Gene 1991; 109:.303 Widegren Ann NY Acad Sci 1984; 438:72 Janne Nucl Acid Res 1989; 17:2359 Eisenberg ref:Aitman, M a m m Genome 1991; 1:206 co:JA Todd ref:Colombo, Nuel Acid Res 1988; 16:9075 co:P Coffino ref:McConlogue, PNAS 1984; 81:540 co:P Coffino J Virol 1989; 63:3810 Frankel M a m m Genome 1992; 2:110 Frankel J Virol 1989; 63:3810 Frankel J Virol 1989; 63:3610 Frankel Immunogenetics 1986; 23:233 Rossomando C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

380 Table 3. Continued. Chr Symbola

12

Pomc-1

LocusName

pro-opiomelanoeortin-a

12 12 12

Pygl Rnrl2 Rnula-2

liver glycogen phosphorylase ribosomal RNA-12 Ula2 small nuclear RNA

12 12

Rnu3b-ps5 U3B small nuclear RNA-3 pseudogene 5 ribonueleotide reductase M2 Rrm2

12 12

Spi-1 Spi-2

serine protease inhibitor - 1 serine protease inhibiter-2 (eontrapsin)

12

Spnb- 1

~-speetrin-1

12

Synd

syndeean

12

"Tg-GH"

human growth hormone transgene

12

Tgfb-3

transforming growth factor, [3-3

Probeb

RFLVc Ccrtiactd

ks9, pMKSU16 [R] pSP-I13 [H] pACYC621 [R] L-GPI B28 U1 RNA specific probe

+ + + +

pmbe P, probe V Rrm2 eDNA, clone 10 pLv1796 + pLv54 + mCPI,mCP2,mCP3,mCP4 kMC-2 + PM-4 p419b-EH + ~.HUGI-I/4-1, pHUGH/4-1 pHUGH/4-1[d] [H] H4 Tgib-3 cDNA pTGF[~3-7, pTGF[33-11 TGF[~3 eDNA +

12 Tpo 12 T s h r 12 Xmmv-21 12 Xmmv-25 12 Xmmv-50 13 add 13 Amh-rs2 13 Ctla-2a

13 13

Ctla-2b Ctla-3

Tgib-3 eDNA-1 [R] prTPO-P [R] T8AFB pMo-MCFI-16 pMo-MCFI-16 pXenv 358-3 genomic pMIS330.5-2 41G 12,43B4,43H5,43D4 Ctla-2a genomic M41G12 cytotoxic T lymphocyte associated prot~2~ ~ , 53F5 cytotoxie T lymphocyte associated protein-3 MllE6 (granzyme A, Hanukah factor) MllE6 pgAl0 Ctla-3 eDNA thyroid peroxidase thyroid stimulating hormone receptor xenotropic-MCF leukemia virus-21 xenotropic-MCF leukemia virus-25 xenotropic-MCF leukemia virus-50 anterior digit pattern deformity anti-Mullerian hormone related seq-2 cytotoxic T lymphocyte associated prot-2a

+ + + + +

+ + +

13 13 13

D13Crcl DNA segment, Chr 13, Clinical Res Ctr-1 "D13Haml" DNA segment, Chr 13, Hamburg-1 "D13McCI" DNA segment, Chr 13, McClelland-1

13 13

D13N1 D13Pasl

DNA segment, Chr 13, NIH-1 DNA segment, Chr 13, Pasteur Iust-1

13 13

D13Pas2 D13Was70

(withdrawn, = Hbvi) DNA segement, Chr 13, Univ of Wash-70

probe 70-38

13

Dhfr

dihydrofolate reduetase

pdhfr 3.2

P198 eDNA p15-4 AP-PCR oligo KA+KB AP-PCR oligo KB clone S112 PLS, PL7 PL5

+ + + +

+ + + pSVMdhfr pDHFRI1 + + 13

Fim-1

Friend MuLV integration site-1

167-PP15, clone 167 51-EH09, cone 51 167-PP15

51-EH09

+ + + + +

Refemncee

M Uhler Chen eo:JL Roberts eo:ACY Chang Glaser Arnheim Schenborn Lund Mazan Thelander Yang-Feng co:Hill co:Hill Suzuki co:Y Ikehara co:PJ Curtis co:PJ Curtis co:PJ Curtis Saunders Oettinger co:B Mintz co:B Mintz Barton Derynck eo:R Derynek Miller Miller co:Miller Pelton Denhez co:S Kimura Akamizu co:M Vogt co:M Vogt co:MA Martin Pohl King Denizot Denizot Brunet Denizot Brunet co:S Gisselbrecht co:Goldstein Gershenfeld co:IL Weissman co:E DePlaen Harbers ce:M McClelland ce:M McClelland co:Feisee & Huppi Leroy co:S Gisselbrecht

J Biol Chem 1983; 258:9444 PNAS 1983; 80:2211 ref: Glaser, Genomics 1989; 5:510 ref:Siracusa, Genetics 1991; 127:169 Genomics 1989; 5:510 PNAS 1982; 79:4677 Nucl Acid Res 1985; 13:6223 Somatic Cell Mol Genet 1988; 14:143 Cytogenet Cell Genet 1991; 56:18 Mol Cell Biol 1986; 6:3433 Genomics 1987; 1:77 Mol Cell Biol 1985; 5:2114 Mol Cell Biol 1985; 5:2114 J Bicchem 1990; 108:344 ref:Ohkubo, Biochem J 1991; 276:337 ref:Laurila, Somatic Cell Mol Genet 1987;13:93 ref:Ciee, Blood 1987; 70:915 ref:Birkenmeier, PNAS 1988; 85:8121 J Cell Biol 1989; 108:1547 Genomics 1991; 11:334 ref:Covarrabias, Mol Cell Biol 1987; 7:2243 ref:Covarrabias, Mol Cell Biol 1987; 7:2243 Onccgene Res 1988; 3:323 EMBO J 1988; 7:3737 ref:Mfllan, Development 1991; 111:131 Mol Endocrinol 1989; 3:1926 Mol Endocrinol 1989; 3:1926 ref:Dickinson, Genomics 1990; 6:505 Development 1990; 110:609 Growth Factors 1990; 3:139 ref:Isozaki, Mol Endocrinol 1989; 3:1681 PNAS 1990; 87:5677 ref:Blatt, PNAS 1983; 80:6298 ref:Blatt, PNAS 1983; 80:6298 ref:Wejman, J Virol 1984; 50:237 Development 1991; 110:1153 Genomics 1991; 11:273 E u r J Immunol 1989; 19:631 E u r J Immunol 1989; 19:631 Nature 1986; 322:268 Eur J Immunol 1989; 19:631 Nature 1986; 322:268 refiSola, J Virol 1968; 62:3973 ref:Justice, Genomics 1990; 6:341 Science 1986; 232:854 ref:Holcombe, Genet Re~ 1991; 58:41 ref:Knight, Mol Cell Probes 1990; 4:497 Cytogenet Cell Genet 1990; 53:129 ref:Welsh, Nucl Acid Res 1991; 19:5275 ref:Welsh, Nucl Acid Res 1991; 19:5275 Nucl Acid Res 1989; 17:10517 Development 1987; 101 (supp): 177 ref:Sola, J Virol 1988; 62:3973

Disteche Disteche Eicher Killary co:GF Crouse co:D Wilson Lee co:S Warren Chang co:Schimke Mock Sola Sola co:Tambourin co:Tambourin co:Sola Holcombe co:S Gisselbrecht co:S Gisselbreeht

Cytogenet Cell Genet 1985; 39:262 Cytometry 1990; 11:119 Genetics 1990; 125:431 Somatic Cell Mol Genet 1986;12:641 ref:Colombo, Mamm Genome 1992; 2:130 ref:Holcombe, Genet Res 1991; 58:41 Nature 1981; 294:228 ref:Fukumoto, Sore Cell Mol Gen 1986; 12:611 Nature 1978; 275:617 ref:Justice, Genomics 1990; 6:341 Immunogenetics 1990; 31:265 J Virol 1986; 60:718 J Virol 1986; 60:718 Justice, Genomics 1990; 6:341 ref:Dickinson, Genomics 1990; 6:505 ref:Meen, Mamm Genome 1991; 1:217 Genet Res 1991; 58:41 ref:Sola, J Virol 1988; 62:3973 ref:Knight, Mol Cell Probes 1990; 4:497 Continued on next p a g e

J.T. Eppig: Clones and Probes

381

Table 3. Continued. Chr S y m ~ a

13

13

13

13 13

13 13 13 13

13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13 13

13 13 13 13

Gas-1

Locus Name

growth arrest specific-1

Pm~

Gas-1 eDNA- 1 Gas-1 eDNA- 1 Gas-1 eDNA-2

RFLVc Contactd

Schneider Colombo + Colombo + co:P D'Eustachio Hbvi hepatitis B virus transgenie insertion site Hbvi genomie Hadehouel pBCu4-12 Hadchouel (= 4/12) + co:Pourcel + co:B Sold + co:S Gisselbrecht pBCu4-12 + co:Pourcel Hexb hexosaminidase mhex54 co:RA Gravel [H] p~HEX43 eo:RA Gravel p~I-IEX54 O'Dowd + co:Triggs-Raine Hilda h u m a n interleukin in DA cells [H] pXM6R Moreau + ca:Wong Histl histone gene complex 1 (H2b, H2a, H3) MM291 Graves (H3.2, H2b, H3.1, H2a) MM221 Graves (H3.1) MM291, pH3.291 Taylor MM221, pMH3-2, pMH2b, Sittman pMH3-1, pMH2a, pMH2b-H3 Sittman Sittman MM221 MM221, MM291 Graves MMHISHSA (mierosat) + eo:JA Todd MM291, MM221 Liu (H2b 3' flank) MH143 co:WF Marzluff (H2A, H3.1) unnamed Koseieesa (H3.2) [Ha] pAAD3.7 Artishevsky (H2b) [C] pH2B ce:P Challoner Hmger 3 -hydroxy-3-methylglutaryl-coenzyme A [CH] Hmgcr eDNA eo:K Luskey, ATCC reductase (HGM-CoA reductase) Htrla 5-hydroxytryptamine (serotonin) la receptor [H]G21 co:U Franeke I1-9 interleukin-9 (P40) P40.2B4 vanSniek + Mock Renauld k,S40.1a Inhba inhibin [~A [H] XhinJ3A2-1 Mason [TI] ~.hin~A14~1 Mason Mason [H] ~.hinJ3A5s Mason [H] ~.hin~A8s [H] Inhba eDNA (derived) co:AJ Mason [I-I] Hu-Inhib-[3A + co:Seeburg,Kaumeyer Lambl-2 laminin-~l subunit 2 pPE386 Barlow + co:Seldin Ltrm-4 LTR mink cell focus-forming murine CI-3-Ltr Rapp + leukemia viral locus-4 Eicher "Mns-13" minor satellite Chr 13 (centromeric) pMmS0 Voliva co:VM C h a p m a n co:ND Hastie Mpmv-33 modified polytropic murine leukemia virus-33 JS-4 + Frankel "Msl-I-6-PI" minisatellite 1-1-6-PI (Drosophila Per) pSP.2.5.EI + Julier "Ms3-1-1-P2" minisatellite 3-1-1-P2 (human D3S45) pEFD134.7 + Julier '2Vls3-1-2-Pl" minisatellite 3-1-2-P1 (human D3S45) pEFD134.7 + Julier "Ms3-2-23-P2" minisatellite 3-2-23-P2 (human D3S45) pEFD134.7 + Julier '2Vls3-2-24-P2" minisatellite 3-2-24-P2 (human D3S45) pEFD134.7 + Julier 'WIs3-3-17-P2" minisatellite 3-3-17-P2 (human D3S45) pEFD134.7 + Julier "Ms4-3-8-P2" minisatellite 4-3-8-P2 (human D2S44) pYNH24 + Julier '~Ms4-3-9-Pl" minisatellite 4-3-9-P1 (human D2S44) pYNH24 + Julier '2Vls5-2-3-P2" minisatellite 5-2-3-P2 pEWRB2.3 + Julier "Ms5-2-4-Pl" minisatellite 5-2-4-P1 pEWRB2.3 + Julier "Ms7-1-5-P2" minisatellite 7-1-5-P2 (human RB1) p68RS2.0 + co:T Dryja "Ms7-3-12-P2" minisatellite 7-3-12-P2 (human RB1) p68RS2.0 + co:T Dryja "Msl0-1-11-Pr miaisatellite 10-1-11-P1 (human D17S5) pYNZ22 + Julier Ncf-2rs neutrophil cytosolic factor-2 related seq [H] NCF2-10 Franeke Nid nidogen clones 6c, 21b, 37a, 40a Mann clones N-2, N-3, N-5 Mann clone 6c + Jenkins pcdJWg Purkinge cell degeneration transgene pFR400 Krulewski pcdJWg genomic + Krulewski Phpp-1 prehormone processing proteinase (Kex2 homology) mPC1 Seidah clones 12A21, 19A1, 6B, 8B Seidah PI-1 placental lactogen-1 clone 1.5 Jackson-Grusby clones 1.5, 1.6, 1.16 co:DIH Linzer Pl-2 placental lactogen-2 PI-2 eDNA Jackson-Grusby Jackson

Cell 1988; 54:787 Nuel Acid Res 1989; 17:5415 Nuel Acid Res 1989; 17:5415 ref:Colombo, M a m m Genome 1992; 2:130 Nature 1987; 329:454 Nature 1987; 329:.454 ref'dtmtiee, Genomies 1990; 6:341 ref:Colombo, M a m m Genome 1992; 2:130 refiSola, J Viroi 1988; 62:3973 ref:Diekinson, Genomies 1990; 6:505 ref:Bapat, FEBS Lett 1988; 237:191 ref:Killary, Somat Cell MoI Genet 1986; 12:641 PNAS 1985; 82:1184 ref~ustice, Genomies 1990; 6:341 Nature 1988; 336:690 ref~tmtice, Genomies 1990; 6:341 J Mol Biol 1985; 183:179 J Mol Biol 1985; 183:179 J Mol Evol 1986; 23:242 Nucl Acid Res 1983; 11:6579 Nuel Acid Res 1983; 11:6679 PNAS 1981; 78:4078 J Mol Biol 1985; 183:179 ref:Aitman, M a m m Genome 1991; 1:206 Nucl Acid Res 1987; 15:3023 tel:Knight, Mol Cell Probes 1990; 4:497 Nucl Acid Res 1989; 17:8861 DNA 1989; 8:301 ref:Rienhoff, Mol Cell Bio 1988; 8:3710 ref:Sundaresan, Sore Cell Mol Gen 1989;15:465 ref:Sundaresan, Sore Cell Mol Gen 1989;15:465 J Exp Med 1989;, 16ff.363 Immunogeneties 1990 ; 31:265 J Immtmol 1990; 144:4235 BBRC 1986; 135:957 BBRC 1986; 135:957 BBRC 1986; 135:957 BBRC 1986; 135:967 ref:Barton, (]enemies 1989; 5:91 ref:Jtmtice, Genomies 1990; 6:341 EMBO J 1984; 3"2355 refdustice, Genomies 1990; 6:341 J Virol 1983; 45:740 Genetics 1990; 125:431 Nuel Acid Res 1983; 11:8847 reEBroccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nuel Acid Red 1983; 11:6965 M a m m Genome 1992; 2:110 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 ref'2ulier, PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4585 PNAS 1990; 87:4585 Am J Hum Genet 1990; 47:483 EMBO J 1989; 8:65 EMBO J 1989; 8:65 Genemies 1991; 9:401 PNAS 1989; 86:3709 PNAS 1989; 86:3709 DNA Cell Biol 1990; 9:415 Mol Endesrinel 1991; 5:111 Endocrinology 1988; 122:2462 ref:Coloai, Mel Endocrinol 1987; 1:767 Endocrinology 1988; 122:2462 PNAS 1986; 83:8496 Continued on next page

J.T. Eppig: Clones and Probes

382 Table 3. Continued. Cbr S y r r ~ a

Locus Name

13

Plf

proliferin

13

Plfr

preliferin-related protein

13 13

Pmv-9 Pmv-41

polytropic murine leukemia virus-9 polytropic murine leukemia virus-41

13

Prl

prolactin

13

Rasa

ras p21 GTPase activating protein

13

Rasll

Ras like family 1

13

Rep-3

repair of chromatin damage-3

13

Rrm2-ps3

(class A) (class B) ribonucleotide reductase M2, pseudo-3

13 13

SrdSa-1 Tcrg

steroid 5a reductase T cell receptor T chain

13

Tcrg-C

T cell receptor T chain (constant)

(constant) CT1, Cy2, C~3

13

Tcrg-J

(constant) CT1 (constant) CT4 T cell receptor T chain (J region)

13 T c r g - V

T cell receptor T chain (variable)

13

Tcrg-Vl

Tcrg-V (T1 family)

13 Tcrg-V2

Tcrg-V(~2 family)

Probeb

PLF-1, PLF-2 PLF-1 PLF42, PLF 149 MRP eDNA PRP-1, PRP-2 PRP-1 JS-5 JS-5 JS-5, MCF100 piT200

RFLVc Cantactd

Linzer co:DIH Linzer Linzer Nilsen-Hamilton Linzer co:DIH Linzer + Frankel + Frankel + Frankel Linzer co:DIH Linzer + co:DIH Linzer [B] Rasa eDNA + co:R Dixon(Merck) [H] Rasa eDNA + eo:R Dixon(Merck) []3] pGAP3 + Hsieh Rasa genomic, 185-7 Hsieh [Sim] pGra/AP Chardin + Justice pgDBG4, pDHH8 Linton pBST402 Linton {29,C13, C48, C72, C91 Linton C130, C107 Linton Rrm2 eDNA Thelander " Yang-Feng + co:Thelander [R] Srd5a-1 probe + Jenkins Tcrg eDNA + Owen + Holcombe pGEMIC Heilig " + co:Barth A14V1V2CT co:A Hayday pTZC~4 Woolf Tcrg-C probe + co:I Rimm TC-11, TC-13, TC-17 Garman 42203, prVJC, pcJC, pc3'uT co:Tonegawa J-C13.4, C7.5, J-C10.5 co:Tonegawa wobeb + Iwamoto 8/10-2Tl.l,5/10-13y1.2 , probe a Iwamote 8/10-2T1.1 + co:Iwamoto T~5 eDNA eo:M Steinmetz pCTT5 Huppi + Mock pHDS4/203, pHDS4, pHDS203 Saito pHDS4 + Kranz Cy2 co:Iwamoto + eo:A Traunecker pBSC 7 co:S Hedrick + Klotz clone 77.1 + Rathbun pTZCT4 + Klotz J$2 + co:JL Hurwitz pAA53, pAA26 co:H Yamagishi T75 eDNA co:M Steinmetz clone T7.1 Rathbun probe a, probe b Iwamoto 8]10-271.1,5/10-13T1.2 Iwamoto pH])$4/203, pHDS4, pHDS203 Saito pHDS4/203 co:H Saito pHDS34, DFL12 co:H Saito 4/203, pcVJC, pcJC, pcV co:Tonegawa J-C13.4, J-C10.5 co:Tonegawa TC-11, TC-13, TC-17 Garman VTT5 + co:S Gisselbrecht T75 eDNA co:M Steinmetz pUCVT1.1 W ool f + Klotz Vy2 + co:A Traunecker V10.8 co:Tonegawa 8/lO-2Tl.l,5/10-13T1.2 , probe a Iwamoto Vy2 + co:A Traunecker pUCVTI.1 Wool f + Klotz 8/10-271.1,5/10-13T1.2 , probe a Iwamoto pHDS4]203, pHDS4, pHDS203 Saito pHDS34, DFL12 co:H Saito 4/203, pcVJC, pcV, pcL, V10.8 co:Tonegawa

Refe~r~ee

PNAS 1985; 82:4356 ref'~lackson-Grusby, Endocrin 1988; 122:2462 EMBO J 1987; 6:2281 Mol Cell Endocrinol 1991; 77:115 EMBO J 1985; 4:1419 ref:Jackson-Grusby, Endocrin 1988; 122:2462 J Viro11989; 63:3810 J Virol 1989; 63:3810 M a m m Genome 1992; 2:110 J Biol Chem 1985; 260:9574 ref:Jackson-Grusby, Endocrin 1988; 122:2462 ref:Holcombe, Genet Res 1991; 58:41 Cytogenet Cell Genet 1989;, 51:1016 Cytogenet Cell Genet 1989; 51:1016 Sore Cell Mol Gen 1989; 15:579 Sore Cell Mol Gen 1989; 15:579 EMBO J 1986; 5:2203 Genomica 1990; 6:341 Mol Cell Biol 1989; 9:3058 Mol Cell Biol 1989; 9:3058 Mol Cell Biol 1989; 9:3058

Mol Cell Biol 1989; 9:3058 Mol Cell Biol 1986; 6:3433 Genomics 1987; 1:77 tel:Justice, Genomics 1990; 6:341 Genomica 1991; 11:1102 J Immunol 1986; 137:1044 Genomics 1987; 1:287 Nature 1985; 317:168 rel~lustice, Genomics 1990; 6:341 tel:Boyle, Genomics 1992; 12:106 Nucl Acid Res 1988; 16:3863 ref:Holcombe, Genet Res 1991; 58:41 Cell 1986; 4.5:733 ref:Hayday, Cell 1985; 40:259 ref:Hayday, Cell 1985; 40:259 J Exp Meal 1986; 163:1203 J Exp Meal 1986; 163:1203 ref:Nobahara, Immunogenetics 1989; 30:405 ref:Snodgraas, Nature 1985; 315:232 Immunogenetics 1986; 24:304 Immunogenetics 1990; 31:265 Nature 1984; 309:757 Science 1985; 227:941 ref:Schuler, EMBO J 1988; 5:2139 ref:Vidard, Immunogenetics 1990; 32:27 ref:Woolf, Nucl Acid Res 1988; 16:3863 Immunogenetics 1989; 29:191 Immunogenetics 1988; 27:121 Immunogenetica 1989; 29:191 ref:Larche, Eur J Immunol 1991; 21:2943 ref:Iwasato, Eur J Immtmol 1992; 22:101 ref:Snodgraaa, Nature 1985; 315:232 Immunogenetica 1988; 27:121 J Exp Med 1986; 163:1203 J Exp Mad 1986; 163:1203 Nature 1984; 309:757 ref:Kranz, Nature 1985; 313:752 ref:Kranz, Nature 1985; 313:752 ref:Hayday, Cell 1985; 40:259 ref:Hayday, Cell 1985; 40:259 Cell 1986; 45:733 reliSola, J Virol 1988; 62:3973 ref:Snodgrass, Nature 1985; 315:232 Nucl Acid Res 1988; 16:3863 Immunogenetica 1989; 29:191 ref:Vidard, Immunogenetica 1990; 32:27 ref:Hayday, Cell 1985; 40:259 J Exp Med 1986; 163:1203 ref:Vidard, Immunogenetica 1990; 32:27 Nucl Acid Res 1988; 16:3863 Immunogenetic~ 1989; 29:191 J Exp Mad 1986; 163:1203 Nature 1984; 309:757 ref:Kranz, Nature 1985; 313:752 ref:Hayday, Cell 1985; 40:259 Continued on next p a g e

J.T. Eppig: Clones and Probes

383

Table 3. Continued. Chr b--'ym~a

13

Tcrg-V3

~

Name

Tcrg-V(73 family)

p~b

RFLVc Ccnt~d

V~2

+

pAA10 pUCV71.1 + V5.7 8/10-2T1.1 , 5/10-13T1.2

probe a 13

Tcrg-V4

Tcrg-V(74 family)

pAA2, pAA21 TC-17 pSP17TV

13

Tcrg-V5

Tcrg-V(75 family)

13

Tcrg-V6

Terg-V(76 family)

pAA35 TC-13 pAA42 TC-II, TC-13 pSPIITV

13 13 13 13

Tcrg-V7 Tcrg-V(77 family) "Tg174" transgene ( h u m a n insulin) " T g T t r - l " flank of h u m a n TTR transgene insert-1 Tkrb tyrosine ldnase receptor B protooncogene

13

Tpi-8

triosephosphate isomerase related seq-8

13

Vgr- 1

Vg-1 related protein

13 13 13 14 14

Xmv-13 Xmv-27 Xmv-55 Acra-2 Ang

xenotropic routine leukemia virus-13 xenotropic murine leukemia virus-27 xenotropic routine leukemia virus-55 acetylcholine receptor a2, neural angiogenin

14

Blk

B lymphoid kinase

14

Bmpl

bone morphogenetic protein-1

+

+

§ pAA12, pAA22 [HI pSV2gpt.hlns

+

pFRK43 pFRK16, Tkrb cDNA ~.18mtkr, pDM-92, pDM-89, pDM-81 [H] pHTPI-5A +

Vgrl +

JS-6flS-10 + JS-6~IS-10 + JS-6+JS-10 + FR] ~ 1 6 ( 9 ) + Ang PCR + Ang genomic clones 102,103,201,205,215 lblk25, lblk28, lblk29, lblk3, lblkS, clone 205 Blk probe + Bmpl-215 + +

14

Bmp2b-1

bone morphogenetic protein 2b-1

14 14 14

Bmp4

bone morphogenetic protein 4 (=2b-1 or 2b-2) 1.6kb BMP4 cDNA calcium channel, L type, l a 2 subunit [R] DHPR-B cytotoxic T lymphocyte associated prot-1 M41D12 7.1.2, A.I.1, C.I.1 CI.1, C1SC4 C.I.1

mBMP2b.7.456 +

Cchlla2 Ctla-1

+ + + +

Cll +

14

Ctla-5

cytotexJe T lymphocyte associated prot-5

14 14

Ctla-6 Ctla-7

cytotexJc T lymphocyte associated prot-6 cytotoxJe T lymphocyte associated prot-7

14 14 14 14 14 14

B10

D12 C134 gGRAF-1 D14Ehll DNA segment, Chr 14, Elizabeth H Lacy-I D14Ehll cDNA "D14H41" DNA segment, Chr 14, H41 cosmid H41 "D14McCI" DNA segment, Chr 14, McClelland-1 AP-PCR oligo KA Es-10 esterase-10 [HI pESD14.1.1 Gjb-2 gap junction membrane channel protein ~2 [R] J32 cDNA (connexin 26) Glud glutamate dehydrogenase [H] Gdh-X

+ + + + + +

Hanauer co:A H a n a u e r [H] pGB2862 Banner + co:C Banner MBG-1 co:NK Moschonas Gnhr+ PCR-3' Lang MUSGNRHGA(microsat) + eo:JA Todd (microsat) + co'JA Todd hpg PCR-3', hpg PCR-5' + L a n g +

14

Gnrh

14

hpg

gonadotrophin-releasing hormone hpg allele (outside hpg deletion) hypogonadal (deletion mutation, see Gnhr)

co:A Traunecker co:H Yamagishi Woolf Klotz co:Tonegawa I wamoto Iwamoto co:H Yamagishi Garman co:D Raulet co:D Raulet (MIT) co:H Yamagishi Garman co:H Yamagishi Garman co:D Raulet co:D Raulet (MIT) co:H Yamaglshi Michalova co:K Y a m a m u r a Klein Klein Martin-Zanca Martin-Zanca Maquat co:LE Maquat Lyons co:Lyons Frankel Frankel Frankel co:J Boulter (Salk) Steinhelper co:BL Valle Dymecki Dymecki Dymecki Kozak Wozney co:JM Wozney co:JM Wozney Wozney co:Woz ney Jones Chin Brunet Brunet co:JF Brunet co:Golstein co:P Golstein Lobe Lobe Crceby Lobe co:CG Lobe co:CG Lobe co:CG Lobe Jenne Jackson Boyle co:M McClelland co:J Squire Hsieh

p~e~

ref:Vidard, Immunogenetics 1990; 32:27 ref:lwasato, Eur J Immunol 1992; 22:101 Nucl Acid Ree 1988; 16:3863 Immtmogeneties 1989; 29:1.91 ref:Hayday, Cell 198,5; 40:259 J Exp Med 1986; 163:1203 J Exp Med 1986; 163:1203 reliIwaaato, Eur J Immunol 1992; 22:101 Cell 1986; 45:733 ref:Woolf, Nucl Acid Res 1988; 16:3863 ref:Klotz, Immunogenetics 1989; 29:191 ref:Iwasato, Eur J Immune] 1992; 22:101 Cell 1986; 45:733 ref.'Iwasato, Eur J Immunol 1992; 22:101 Cell 1986; 45:733 refiWoolf, Nucl Acid Res 1988; 16:3863 refiKlotz, Irnmunogenetics 1989; 29:191 refilwasato, Eur J Immunol 1992; 22:101 H u m Genet 1988; 8~.247 ref:Wakasugi, Devel Genet 1988; 9:203 EMBO J 1989; 8:3701 EMBOJ 1989; 8:3701 Genes & Devei 1990; 4:663 Genes & Devel 1990; 4:683 J Biol Chem 1985; 26~.3745 refiSiracusa, Genetics 1991; 127:169 PNAS 1989; 86:4554 ref:Diekinson, Oenomics 1990; 6:505 J Virol 1989; 63:1763 J Virol 1989; 63:1763 M a m m Genome 1992; 2:110 ref:Be~s, FEBS Lett 1990; 264:48 Genomics 1992; 12:177 ref:Bond, BBRC 1990; 171:988 Science 1990; 247:332 J Biol Chem 1992; 267:4815 J Biol t h e m 1992; 267:4815 Genomies 1991; 9:762 Science 1988; 242:1528 ref:Ceci, Genomics 1990; 6:673 ref:Gleditsch, Immunogenetics 1992; 35:153 Science 1988; 242:1528 ref:Dickinson, Genomics 1990; 6:505 Development 1991; 111:531 Genomics 1991; 1:914 Nature 1986; 322:268 Nature 1986; 322:268 refiHarper, Immunogenetics 1988; 28:439 ref:Ceci, Genomice 1990; 6:673 ref:Gleditsch, Immunogeneth:s 1992; 35:153 PNAS 1986; 83:1448 Science1986; 232:858 Genomics 1990; 6:252 PNAS 1986; 83:1448 refiCrceby, Genomics 1990; 6:252 ref:Crosby, Genomics 1990; 6.252 ref:Crosby, Genomics 1990; 6:252 J Immuno11991; 147:1045 EMBOJ 1992; 11:527 Genomics 1992; 12:106 res Nucl Acid Res 1991; 19:5275 ref.'Stone, Genomics 1989; 5:70 Sore Cell Mol Genet 1991; 17:191 Nucl Acid Res 1987; 15:6038 refiHarper, Immunogenetics 1.988; 28:439 J Neurechem 1986; 49"246 ref:Shaughncesy, Nucl Acid l~as 1989; 17:2881 refiTzimagiorgis, BBA 1991; 1089:250 Mouse Genome 1991; 89:857 ref:Hearne, M a m m Genome 1,991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 Mouse Genome 1991; 89:857 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

384 Table 3. Continued. Clar Symbda

Locus Name

hr

hairless

14

14 14

14 14 14 14 14 14 14 14 14 14 14 14

14

14

14 14 14 14 14 14

14 14

Probeb

MX40B/BgX MX40A, MX4OB, BgE BgX

RFLVc Ccnlac~1

+

co:J Stoye cod Stoye + cod Stoye + co.d Stoye + cod Stoye co:J Stoye + co:J Stoye h r microsat + cod Stoye Htr2 5-hydroxytryptamine (serotonin) receptor 2 [R] 5HT-2 eDNA Sparkes + Liu "Mns-14" minor satellite Chr 14 (eentromeric) pMR150 Voliva co:VM C h a p m a n co:ND Hastie Ms6-5 minisatellite 6-5 [H] probes 33.6 Jeffreys Ms15-7 minisa tellite 15-7 [H] prob~ 33.15 Jeffreys "Ms4-2-3-P2" minisatellite 4-2-3-P2 (human D2S44) pYNH24 + Julier "Ms4-2-16-Pl" minisatellite 4-2-16-P1 (human D2S44) pYNH24 + Julier "Ms4-3-7-Pl" minisatellite 4-3-7-P1 (human D2S44) pYNH24 + Julier "Ms4-2-7-Pl" minisatellite 4-2-7-P1 (human D2S44) pYNH24 + Julier "Ms7-2-9-Pl" minisatellite 7-2-9-P1 (human RB1) p68RS2.0 + co:T Dryja "Ms7-2-13-P2" minisatellite 7-2-13-P2 (human RB1) p68RS2.0 + co:T Dryja "Ms10-2-5-P2" minisatellite 10-2-5-P2 (human D17S5) pYNZ22 + Julier "Msll-2-5-PI" minisatellite 11-2-5-P1 (human D17S24) pRMU3 + Julier "Msll-3-6-PI" minisatenite 11-3-6-P1 (human D17S24) pRMU3 + Julier Mtv-ll m a m m a r y tumor virus locus-ll MuMTV frag (C3H/He) Prakash MTV env probe + Koizumi MMTV eDNA or DNA + cod Ball, J Majors MMTVS~21,MMTV8-29 + Lee MMTV 3' + co:G Peters pTZ18R-ORF + c o d e Majors Myhc-a myosin heavy chain, cardiac muscle, adult pMHC101, pMHC141 + Weydert (a protein) pMHC101 + co:Weydert Myhc-a (EB cells) Robbins CosMHC-1, CosMHC-2 cod Robbins ~-37, ).-19 cod Robhins Myhc-a eDNA co:J Robbins Myhc-b myosin heavy chain, cardiac muscle, Myhc-b (EB cells) Robbins fetal (~ protein) CosMHC-1, CosMHC-2 co:J Robhins k-37, 7-19, ~-2A, X[~-IA cod Robbins Myhc-b eDNA co:J Robbins Nfl neurofilament, light polypeptide (68 kDa) Nfl eDNA co:F Grosveld co:JP Julien cosIC3, Nfl cDNAI co:F Grosveld NF68 Lewis co:Lewis kL2, kL10, kL26 co:WW Schlaepfer MMNFIL (microsat) + codA Todd (microsat) + co:JA Todd Nfm neurofilament, medium polypeptides cesIC3 co:F Grosveld Nfm eDNA, kNF-M co:F Grosveld ~/i13 co:WW Sehlaepfer Np-1 nucleoside phosphorylase- 1 NI>I eDNA, Np-I-PCR co:FF Snyder Nras-ps neureblastoma ras oncogene pseudogene probes: N8.5, N2.7 Ryan Odc-rs9 ornithine decarboxylase related seq-9 pMK217,pMK934 or pMK3048 + 1-EUiott,Berger Otf3-rs6 Otf-3 related sequence-6 3' Otf-3 eDNA + Siracusa Plau plasminogen activator, urokinase pDB15, pDB18, pDB29 Belin pDBg, pDB16 Belin pDB15 Collart co:RJ Riekles pDB1519 co:D Belin + co:D Belin + co:D Belin Plau eDNA, cos MuPA-1 Degen pB3.5,pE2.0,pE1.6,pE4.0,pB5.0 Degen MMUPAA (microsat) + c o d a Todd (micresat) + c o d a Todd MMURKR (microsat) + codA Todd Psp-2 parotid secretory protein-2 HhaI-Psp probe Shaw + co:Shaw + co:Shaw Rarb retinoic acid receptor mRAR[$-cDNA co:P Chambon + co:P Chambon Mattei [H] pCOD20 deThe + co: DeJean

Refe~r~acee

Cell 1988; 54:383 Cell 1988; 54~83 Cell 1988; 54:383 refiDickinson, Genomies 1990; 6:505 ref:Ceei, Genomics 1990; 6:673 tel:Knight, Mol Cell Probes 1990; 4:497 ref:Gleditsch, Immunogenetics 1992; 35:153 ref:Hearne, M a m m Genome 1991; 1:273 Genomics 1991; 9:461 Genomics 1991; 11:231 Nucl Acid Res 1983; 11:8847 tel:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1983; 11:6965 Nucl Acid Res 1987; 15:2823 Nucl Acid Res 1987; 15:2823 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 refdulier, PNAS 1990; 87:4585 tel:Juliet, PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 J Virol 1985; 54:285 BBRC 19~, 166:336 ref:Maclnnes, Virology 1984; 132:12 J Virol 1990; 64:4568 ref:Dyson, Nature 1991; 349:531 ref:Pullen, J Exp Med 1992; 175:41 PNAS 1985; 82:7183 ref:Beisel, Nucl Acid Res 1989; 17:10519 J Biol Chem 1990; 265:11905 refd Biol Chem 1991; 266:9180 refd Biol Chem 1991; 266:9180 ref:Sanchez, J Biol Chem 1991; 266:22419 J Biol Chem 1990; 265:11905 ref:J Biol Chem 1991; 266:9180 ref:J Biol Chem 1991; 266:9180 ref:Sanchez, J Biol Chem 1991; 266:22419 ref:Julien, Mol Brain Res 1986; 1:243 ref:Mattei, Biol Cell 1989; 67:235 refdulien, Mol Brain Res 1986; 1:243 J Cell Biol 1985; 100:843 ref:Somerville, Genome 1988; 30:499 ref:Shneidman, Mol Brain Res 1992; 13:127 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 refdulien, Mol Brain Res 1986; 1:243 ref:Julien, Mol Brain Res 1986; 1:243 ref:Shneidman, Mol Brain Res 1992; 13:127 ref:Jenuth, Nucl Acid Res 1991; 19:1708 Nucl Acid Res 1984; 12:6063 ref: Richards-Smith, MNL 1984; 71:46 Genomics 1991; 10:313 Eur J Biochem 1985; 148:225 E u r J Biochem 1985; 148:225 J Immunol 1987; 139:949 refiRajput, Soraat Cell Mol Genet 1987; 13:581 ref:Ceci, Genomics 1990; 6:673 ref:Moen, Marnm Genome 1991; 1:217 ref:Gleditsch, Immunogenetics 1992; 35:153 Biochemistry 1987; 26:8270 Biochemistry 1987; 26:8270 ref:Hearne, Marnm Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 tel:Airman, Manun Genome 1991; 1:206 J Mol Biol 1986; 192:587 ref:Siracusa, Genetics 1989; 122:669 ref:Ceci, Genomics 1990; 6:673 refiZelent, Nature 1989; 339:714 ref:Siracusa, Genemics 1991; 10:313 Genoraic~ 1991; 10:1061 Nature 1987; 330:587 ref:Ceci, Genomics 1990; 6:673 Continued on next page

J.T. Eppig: Clones and Probes

385

Table 3. Continued. Cl'w Symbola

Locus Name

Probeb

14

Rb-1

retinoblastoma- 1

pMRB102 [H]RB1 cDNA pmrb115

14

Rbp-3

retinal binding protein-3, interstitial

14

Rib-1

ribonuclease- 1, pancreatic

IRBP cDNA [B] IRBP10-1800 [B] IRBP-900 pMRP-1 " "

14 14 14 14 14

Sftp-1 Sftp-2 slt sys Tcra

pulmonary surfactant apoprotein-1 pulmonary surfactant apoprotein-2 slaty (see Tyrp-2) symplastic spermatids T cell receptor a chain

14 Tcra-C

T cell receptor a constant region

14

T cell a chain (J region)

Tcra-J

RFLVc C ~ t ~ I

+

+ + + + +

+ M7 clones 5(15, 7G8, 15C10, clones 17D3, 12A10, l l H 2 [R] pCXP6-105 pmSPA1.2H + [H] p2.1 + Zap 1 probe + T1.2 + BDFL2.5, BDFLg.1 BDFL Kpn7.5 HYal D6a + MMTCA4 (microsat) + A10,TA4.1,TA30.1,TA50.1 A10 + TAB4, TA46, TA31, TA39 TA26, TA28, TA65, TA72 TA1, TA27, TA61, TA37 TA38, TA45, TA19, TA80 TA57, TA20, TA91 TA26, TA28 + Tcra-B10, Tcra-4.C3 Tcra-C.F6, Tcra-5C.C7 TT11

Stone co:W-H Lee Bernard co:R Bernard Liou co:DB Farber co:DB Farber co:MH Meisler co:Samuelson,Meisler co:MH Meisler co:MH Meisler co:MH Meisler Samuelson Schuller Schuller Schuller cn:NG Copeland co:NG Copeland

MacGregor co:Dembic co:Dembic co:Z Dembic co:Y U e m a t s u co:J Danska Montagutelli Winoto co:Winoto Arden Arden Arden Arden Arden Klotz Fink Fink Chien C5a, Ela,MDAa,FNI-18a Becker MD13a,P71a,LB2a,2B4a Becker Ja34, Ja42, JaDO, co:E Palmer Ja3DT,Ja45,Ja20,Ja49 co:E Palmer pUCCal + Klotz + co:A Arden,LE Hood + co:R Snodgrass T1.2 Snodgrass pHDS58 Saito Kranz probe Aa (from HYal) + co:Y U e m a t s u probe Ba (from BDFL Kpn7.5) + co:Z Dembic Cal.2 co:E Palmer 5/10-20 Da Iwamoto + co:Iwamoto plca Iwamoto + co:T Mak + co:T Mak Tcra-C3' + Weiss cosmid BDFLg.1 Dembic Ca2 Dembic Thompson Ca3 + co:S Tonegawa ppaDO Epstein Yague clones ;~3.9, )~6.2, ~.'1.2 Hayday clone ),'5.1, cosmid l lE Hayday pHDS58, clone k2.2 Hayday Ja34, Ja42, JaDO, co:E Palmer Ja3DT,Ja45,Ja20,Ja49 co:E Palmer A10,TA4.1,TA30.1,TA50.1 Winoto TA25.1,TA28.1,TA52.1 Winoto TA5.1,TA8.1,TAS0.1 Winoto TA84, TA46, TA31, TA39 A r d e n TA26, TA28, TA65, TA72 Arden TA 1,TA2 7,TA61,TA37,TA20 Arden TA45, TA19, TA80, TA57 A r d e n Tcra-B10, Tcra-AN6.2 Winoto Tcra-V11.5, Tcra-C.F6 Winoto

Referencee

Genomics 1989; 5:70 ref.'Hsieh, Sore Cell Mol Gen 1989; 15:461 PNAS 1989; 88:6474 ref:Ruggerl, Canc Res 1991; 51:6615 J Biol Chem 1990; 265:8373 ref:Danciger, Genomies 1990; 8:727 ref:Danciger, Genomics 1990; 8:727 refiRW Elliott, Cytogen Cell Genet 1986; 42:110 ref:Crosby, Genomics 1990~; 6:252 ref:Ceci, Genomics 1990; 6:873 ref:Nakajima, Immunogenetics 1992; 35:190 ref:Gledit~ch, Immunogenetics 1992; 35:153 Nucl Acid Res 1991; 19:6935 Mol Biol Evol 1990; 7:29 Mol Biol Evol 1990; 7:29 Mol Biol Evol 1990; 7:29 ref:Moore, Genomies 1992; 12:388 ref:Moore, Genomics 1992; 12:388 PNAS 1990; 87:5016 Nature 1985; 314:271 Nature 1985; 314.'271 ref:Thompson, J Immunol 1990; 145:2347 ref:Thoml~on, J Immtmol 1990; 145:2347 ref:Knight, Mol Cell Probes 1990; 4:497 M a m m Genome 1991; 1:255 Nature 1985; 316:832 ref:Harper, Immtmogenetics 1988; 28:439 Nature 1985; 316:783 Nature 1985; 316:783 Nature 1985; 316:783 Nature 1985; 316:783 Nature 1985; 316:783 Immunogenetics 1989; 29:191 Nature 1986; 321:219 Nature 1986; 321:219 Nature 1984; 312:31 Nature 1985; 317:430 Nature 1985; 317:430 ref:Yague, Nucl Acid Res 1988; 16:11355 ref:Yague, Nucl Acid Res 1988; 16:11355 Immunogenetics 1989; 29:191 ref:Gleditsch, Immtmogenetics 1990; 32:297 ref:Glcditsch, Immunogenetics 1992; 35:153 Nature 1985; 315:232 Nature 1984; 312:36 Science 1985; 227:941 ref:Larche, Eur J Immunol 1991; 21:2943 ref:Larche, Eur J Immunol 1991; 21:2943 ref:Larche, Eur J Immunol 1991; 21:2943 J Exp Meal 1987; 165:592 ref:Nobuhara, Immtmogenetics 1989; 30:405 J Exp Med 1987; 165:592 ref:Dickinson, Genomics 1990,; 6:505 ref:Ceci, Genomics 1990; 6:673 J Immunogenet 1989; 16:283 Nature 1985; 314.'271 Nature 1985; 314.'271 J Immuaoi 1990; 145:2347 ref:Jouvin-Marche, Immunogenet 1989; 30:99 J Exp Meal 1986; 163:759 Cell 1985; 42:81 Nature 1985; 316:828 Nature 1985; 316:828 Nature 1985; 316:828 ref:Yague, Nucl Acid Res 1988; 16:11355 ref:Yague, Nucl Acid Rea 1988; 16:11355 Nature 1985; 316:832 Nature 1985; 316:832 Nature 1985; 316:832 Nature 1985; 316:783 Nature 1985; 316:783 Nature 1985; 316:783 Nature 1985; 316:783 Nature 1986; 324:679 Nature 1986; 324:679 Continued on next page

J.T. Eppig: Clones and Probes

386 Table 3. Continued, Cbr Symbola

14 Tcra-J

Le~usName

Probeb

T cell a chain (J region)

RFLVc C ~ t ~

Tcra-BC15.1, Tcra-4.C3 Tcra-AN14.4, Tcra-5C.C7 Tcra-BC37.5, Tcra-V1.9.2 2B4a, Tcra-AP11.2 Tcra-B10, Tcra-4.C3 Tcra-C.F6, Tcra-5C.C7 TT 11 ppaDO C5a, E1a,MDAa,FNl-18a

MD13a,P71a,LB2a,2B4a 14 14 14 14

Tcra-V Tcra-V Tcra-V Tcra-V

T T T T

cell cell cell cell

receptor receptor receptor receptor

a a a a

chain-variable chain (VBMA) chain (VBMB) chain (VBWB)

14

Tcra-V1

T cell receptor a chain(Val)

TCR-F5 -ALPHA 32.1W7 VaBM-A VaBM-B VaBW-B

A10, Va5H TTll, TAB4, TA46, TA31 TAB4, TA46, TA31 + C5a, E l a Val "

pUCVal " TTll 14 Tcra-V2

T cell receptor a chain (Va2)

+ + + +

+

+ + + + + + +

Va2 + + + +

TA39, TA19 TA19 TA39 + pUCVa2(T39 subclone) , * 14

Tcra-V3

T cell receptor a chain (Va3)

pHDS58 , +

TA26

14 Tcra-V4

T cell receptor a chain (Va4)

" VaF3.5 VaF3 Va3 pHDS58, clone ).2.2 TA28, TA65 TA28, MD13, BDFL2 TA28 TA65 Tcra-APll.2 TNP MD 13a TCR-F5 -ALPHA Va4.4

+ +

+ + + +

+

+ + + + 14

Tcra-V5

T cell receptor a chain (Va5)

MDA, TA80 TA80 TA72

+ +

MDAa pUCVaS(TA72 subclone) + + VaS. 1 +

Winoto Winoto Winoto Winoto Fink Fink Chien Epstein Yague Becker Becker Palmer co:Malissen Jouvin-Marche Jouvin-Marche Jouvin-Marche co:M Malissen Winoto Wilson Arden Becker Malissen co:M Malissen co:J Kobori (CIT) co:A Arden,LE Hood co:A Arden,LE Hood co:L Hood Chien co:M Davis co:E Lai Malissen co:M Malissen co:M Malissen co:S Hedrick Arden Wilson co:E Lai co:J Kobori (CIT) co:A Arden,LE Hood co:A Arden,LE Hood Saito co:Saito Crosby Kranz Eicher Arden Wilson co:A Arden,LE Hood co:A Arden,LE Hood Chou Behlke co:S Tonegawa Hayday Arden Wilson Klotz co:E Lai Winoto Hochgeschwender Becker Palmer co:E Palmer co:E Palmer co:A Arden,LE Hood co:A Arden,LE Hood co:M Kronenberg Wilson Arden Arden co:E Lai Becket co:J Kobori (CIT) co:A Arden,LE Hood co:A Arden,LE Hood Bill eo:E Palmer

Referencee

Nature 1986; 324:679 Nature 1986; 324:679 Nature 1986; 324:679 Nature 1986; 324:679 Nature 1986; 321:219 Nature 1986; 321:219 Nature 1984; 3 1 2 : 3 1 J ExpMed 1986; 163:759 Cell 1985; 42:81 Nature 1985; 317:430 Nature 1985; 317:430 Nuci Acid Res 1989; 17:2353 ref:Jenne, J Immunol 1991; 147:1045 Immtmogenetics 1989; 30:99 lmmunogenetics 1989; 30:99 Immunogenetics 1989; 30:99 ref:Gleditsch, Immunogenetics 1992; 35:153 Nature 1985; 316:832 Immunol Rev 1988; 101:150 Nature 1985; 316:763 Nature 1985; 317:430 Cell 1988; 55:49 ref:Rubin, Immunogenet 1990; 31:207 ref:Klotz, Immunogenetics 1989; 29:191 ref:Gleditsch, Immunogenetics 1990; 32:297 refiGleditsch, Immunogenetics 1992; 35:153 ref:Nakajima, Immtmogenetics 1992; 35:190 Nature 1984; 312:31 ref:Jouvin-Marche, Immunogenet 1989; 30:99 ref:Singer, PNAS 1988; 85:7729 Cell 1988; 55:49 ref:Rubin, Immtmogenet 1990; 31:207 ref:Jouvin-Marche, Immunogenet 1989; 30:99 tel:Bailey, Eur J Immunol 1991; 21:959 Nature 1985; 316:783 Immunol Rev 1988; 101:150 ref:Singer, PNAS 1988; 85:7729 ref:Klotz, Immunogenetics 1989; 29:191 ref:Gleditsch, Immunogenetics 1990; 32:297 ref:Gleditseh, Immunogenetics 1992; 35:153 Nature 1984; 312:36 ref:Berman, Immtmogenetics 1986; 24:328 Genomics 1990; 6:252 Science 1985; 227:941 Genetics 1990; 125:431 Nature 1985; 316:783 Immunol Rev 1988; 101:150 refiGleditsch, Immunogenetics 1990; 32:297 ref:Gleditach, Immunogenetics 1992; 35:153 EMBO J 1986; 9:2149 PNAS 1986; 83:767 ref:Jouvin-Marche, Immunogenet 1989; 30:99 Nature 1985; 316:828 Nature 1985; 316:783 Immunol Rev 1988; 101:150 Immunogenetics 1989; 29:191 ref:Singer, PNAS 1988; 85:7729 Nature 1986; 324.'679 Nature 1987; 326:307 Nature 1985; 317:430 Nucl Acid Res 1989; 17:2353 ref:Yague, Nucl Acid Res 1988; 16:11355 ref:Jouvin-Marche, Immunogenet 1989; 30:99 ref:Gleditsch, Immunogenetics 1990; 32:297 ref:Gleditsch, Immunogenetics 1992; 35:153 ref:Rubin, Immunogenet 1990; 31:207 Immunol Rev 1988; 101:150 Nature 1985; 316:783 Nature 1985; 316:783 ref:Singer, PNAS 1988; 85:7729 Nature 1985; 317:430 ref:Klotz, Immunogenetics 1989; 29:191 ref:Gleditsch, Immunogenetics 1990; 32:297 ref:Gleditsch, Immunogenetics 1992; 35:153 PNAS 1988; 85:9184 ref:Jouvin-Marche, Immunogenet 1989; 30:99 Continued on next p a g e

J.T. Eppig: Clones and Probes

387

Table 3. Continued. Ctw Symbola

Locus Name

14

Tcra-V6

T cell receptor a chain (Va6)

14

Tera-V7

T cell receptor a chain (Va7)

14

Tcra-V8

T cell receptor a chain (Va8)

p/x~b

RFLVc Contactd

TA1

+ + pUCVa6(TA1 subclone) + + + Va6 probe + Va6.1 + + TA27 + + pUCVa7(TA27 subclone) + + + EXP2B4 Va7.2 + TA61

Arden eo:E Lai eo:J Kobori (CIT) co:A Arden,LE Hood eo:A Arden,LE Hood Malissen eo:M Kronenburg Bill co:E Palmer co:E Palmer Arden co:E Lai co:J Kobori (CIT) co:A Arden,LE Hood co:A Arden,LE Hood Chien Kotzin co:E Palmer + co:E Palmer Arden + co:E Lai +

~o~

+ +

co:A Arden,LE Hood co:A Arden,LE Hood Chou Chou Chou Becker co:E Palmer Bill eo:E Palmer Arden co:E Lai co:J Kobori (CIT) co:A Arden,LE Hood co:A Arden,LE Hood Bill co:E Palmer Arden Wilson Becker Malissen co:M Malissen co:M Malissen co:M Malissen Wilson co:E Lai Winoto Fink Winoto Fink Winoto Winoto Winoto Winoto Becker Klotz

MVAF32, MVAF33, MVAF34, MVAF35, MVAF 36, MVAF31 P71a, LB2a VaS.4 Va8.3 + 14

Tcra-V9

T cell receptor a chain (Va9)

TA37 + pUCVa9(TA37 subclone)+ + Va9.1 +

14 Tcra-V10

T cell receptor a chain (Val0)

TA57 TA57, FNll8, VA2B4 FNI-18a Val0 + + "

H

Tcra-Vll

T cell receptor a chain (VRll)

VACF6 Vall.l-Ja84 Tcra-B 10, Tcra-4.C3

+

+

Tcra-5C.C7, Tcra-C.F6 Tera-BC15.1, Tera-AN6.2 Tcra-AN14.4, Tcra-Vll.5 Tcra-BC37.5, Tcra-V1.9.2 2B4a pUC2B4 Vall

14 14

Tcra-V12 Tcra-V13

T cell receptor tt chain (Val2) T cell receptor tx chain (Val3)

pGEM-Vall Vall.3 BDFLI Val2

+

Malissen

+ + + + + + +

VA13 Va13.1,Va13.2

ppaDO

14 Tcra-V15 14 Tcrd-C

T cell receptor a chain (Val5) T cell receptor 5 chain-constant

+ + +

co:E Palmer co:E Palmer co:E Palmer Epstein

+ + +

Yague co:AJ Caton Klotz Jouvin-Marche co:M Malissen co:T Mak

SJL-HE-L1 Va probe pC8 ptube 15 Tcrd-C probe

co:M Malissen co:E Palmer co:E Palmer co:L Hood eo:A Korman Dembic co:Z Dembic co:Z Dembic co:Costlow (unpubl)

Nature 1985; 316:783 ref:Singer, PNAS 1988; 85:7'729 refiK]otz, Immunogenetics 1989; 29:191 ref:Gleditseh, Immunogenetics 1990; 32:297 ref:Gleditsch, Immunogenetics 1992; 35:153 Cell 1988; 55:49 ref: Rubin, Immunogenet 1990; 31:207 PNAS 1988; 85.9184 ref:Jouvin-Marche, Immunogenet 1989; 30:99 ref:Larche, Eur J Immtmol 1991; 21:2943 Nature 1985; 316:783 tel:Singer, PNAS 1988; 85:7729 ref:Klotz, Immunogenetics 1989; 29:191 ref:Gleditseh, Immunogenet~cs 1990; 32:297 ref:Gieditsch, Immunogenetiics 1992; 35:153 Nature 1987; 327:677 J Exp Med 1987; 165:1237 ref:Yague, Nucl Acid IRes 1988; 16:11355 refiJouvin-Marche, Immunogenet 1989; 30:99 Nature 1985; 316:783 ref:Singer, PNAS 1988; 85:7729 Immunogenetica 1989; 2 9 : 1 9 1 ref:Gleditsch, Immunogenetics 1990; 32:297 ref:Gleditsch, Immunogenetics 1992; 35:153 EMBO J 1986; 5"2149 EMBO J 1986; 5".2149 EMBO J 1986; 5:2149 Nature 1985; 317:430 refiYague, Nucl Acid Res 1988; 16:11355 PNAS 1988; 65:9184 ref:Jouvin-Marche, Immtmogenet 1989; 30:99 Nature 1985; 316:783 ref:Singer, PNAS 1988; 85:7729 ref:Klotz, Immunogenetics 1989; 29:191 ref:Gleditsch, Immunogenetics 1990; 32:297 ref:Gleditsch, Immunogenetics 1992; 35:153 PNAS 1988; 85:9184 ref.'Jouvin-Marche, Immuno~enet 1989; 30:99 Nature 1985; 316:783 Immunol Rev 1988; 101:150 Nature 1985; 317:430 Cell 1988; 55:49 refiRubin, Immunogenet 1990; 31:207 ref:Jouvin-Marche, Immunogenet 1989; [email protected] ref:Gleditseh, Immunogenetica 1992; 35:153 Immunol Rev 1988; 101:150 ref:Singer, PNAS 1988; 85:7729 Nature 1986; 324:679 Nature 1986; 321:219 Nature 1986; 324:679 Nature 1986; 321:219 Nature 1986; 324:679 Nature 1986; 324:679 Nature 1986; 324:679 Nature 1986; 324:679 Nature 1985; 317:430 Immunogenetics 1989; 29:191 Cell 1988; 55:49 ref:Rubin, Immunogenet 1990; 31:207 ref.'Gleditsch, Immunogenetics 1990; 32:297 ref:Gleditech, Immunogenetics 1992; 35:153 ref:Nakajima, Immunogenetics 1992; 35:190 refiJouvin-Marche, Immunogenet 1989; 30:99 Nature 1986; [email protected] ref:Gleditseh, Immunogenetic~ 1990; 32:297 res Immunogenetic~ 1992; 35:153 ref.'Wilson, Immunol Rev 1988; 101:150 ref:Yague, Nuel Acid Res 1988; 16:11355 ref:Gleditsch, Immunogenetics 1990; 32:297 ref:Gleditseh, Immunogenetics 1992; 35:153 J Exp Med 1986; 163:759 Cell 1985; 4 2 : 8 1 ref:Sutherland, Immunogenet 1991; 34:372 Immunogenetics 1989; 2 9 : 1 9 1 Immunogenetics 1989; 3 0 : 9 9 ref:Larche, Eur J Immunol 1991; 21:2943 ref:Gleditseh, Immunogenetics 1992; 35:153 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

388 Table 3. Continued. Chr Symbda

Locx~Name

14 Tcrd-D 14 Tcrd-J 14 Tcrd-V1 14 Tcrd-V2

T T T T

14 14 14 14 14 14

Tcrd-V3 Tcrd-V4 Tcrd-V5 Tcrd-V6 Tcrd-V7 Tpi-9

T cell receptor 5 chain (V53) T cell receptor 5 chain (V54) T cell receptor 5 chain (V55) T cell receptor 8 chain (V56) T cell receptor 5 chain (V57) triosephosphate isomerase related seq-9

14

Trp53-ps

transformation related p53, pseudogene

14 14 14 15

Tyrp-2 Wnt-SA Xmv-19 Acr

15 15

Amh-rs7 Col2a-1

15

Cyp2d

15

Cyp2d9?? CypHb-1

cytochrome P450, testis steroid- 1 l~-hydroxylase

15

Cypllb-2

steroid- ll~-hydrexylase (aldosterone synthase)

15

D15Kzl

DNA segment, Chr 15, Kozak-1

15 15

Ela-1 F3cam

elastase- 1 F3 neuronal cell adhesion molecule

15

Gdc-1

glycerelphosphate dehydrogenase-1

15

Ghr

growth hormone receptor

15

Hba-ps3

hemogloblin a , pseudogene-3

15 15

Hbr- 1 Hox-3

cell cell cell cell

receptor receptor receptor receptor

Probeb

5 chain-J region 5 chain-J region 5 chain (VS1) 8 chain (V52)

RFLVc Coatsctd

~i M9 V52.3 Mll Z68 dn4 Z44

V57.1 [H] pHTPI-5A

+ + + + + + + +

+ pCH53-11 pp53-176 Ch53-11, pCh53-11 + MMP53P (microsat) + clone 5A tyrosinase related protein-2 wingless-related MMTV integration site-5A Wnt-5A cDNA xenotrepic murine leukemia virus-19 JS-6flS-10 + preproacrosin pma3, pma7, pmal0 MA7, MAll, MA12, MA13 XNIac28 Acr cosmid [R] pRMIS1 + anti-Mullerian hormone related seq-7 procollagen type II, a-1 pMCol2al-1 Col2a-1 cosmid cytochrome P450 IID unnamed (C-P45016a male-specific) [R] dbl, [R] db2 pl6a-1

hormone binding receptor- 1 homeo box-3 cluster

pl6-c~,pl6c~16 Cyp2d9 eDNA Oh- 11~ eDNA Cypll cosnfid ll~-OHase probe + Cypll cosmid genomic Oh-ll~ AS probe EC-8 + clone 2, clone 6, 4.8/6 [R] pXP13 DI.1 clones 25.1,25.2,71.1,19.1 pea + + + + + gd c- 1 + + + + + + ixxi~ B clone F12, exon2-probe + Gdc-1 genomic clone 2, clone 6, 4.8/5 + MMGPD (microsat) (microsat) + [RAB] GHR eDNA [RAB] pBR-HGHR + [H] pBR-HGHR phage clone 2 (= a-~3) + u N10 eDNA, ;LF2 XlVlo-EA, pMoEA pMo-EA pm31. lc Hox-3.1 probe + MMHOX31R (microsat) + (micros,at) +

co: Sakano (UCB) co: Sakano (UCB) co:Y Chien Jouvin-Marche co:Y Chien co:Y Chien co:Y Chien co:Y Chien co:Y Chien Jouvin-Marche Maquat co:LE Maquat Zabu~Houri Czosnek Oren co:JA Todd Jackson Gavin Frankel Klemm Kashiwabara co:T Baba Kremling co:RL Cate, Biogen co:E Vuorio co:E Vuorio Kimura Gonzalez Harada Wong Wong Virbasius Rice co:KL Parker co:KL Parker co:KL Parker Mouw co:KL Parker co:LP Kozak co:LP Kozak Honey Gennarini Gennarini co:Kozak Eicher co:E Birkenmeier co:E Birkenmeier Eicher co:LP Kozak Kozak co:LP Kozak co:LP Kozak co:LP Kozak Prochazka Gwynn co:LP Kozak co:LP Kozak co:LP Kozak co'AA Todd co:JA Todd Smith Leung co:WI Wood Barton Loder co:P Leder Eicher Vanin Ryseck Awgulewitsch co:Awgulewitsch Breier co:B Mock co:JA Todd eo:JA Todd

ref: Klotz, Immunogenetics 1989; 29:191 ref: Klotz, Immunogenetics 1989; 29:191 ref:Gleditach, Immunogenetics 1992; 35:153 Immunogenetics 1989; 30:99 ref:Gleditsch, Immunogenetics 1992; 35:153 ref:Gleditsch, Immunogenetics 1992; 35:153 ref:Gleditach, Immunogenetics 1992; 35:153 ref:Gleditach, Immunogenetics 1992; 35:153 ref:Gleditach, Immunogenetics 1992; 35:153 Immunogenetics 1989; 30:99 J Biol Chem 1985; 260:3748 ref:Siracusa, Genetics 1991; 127:169 Nature 1983; 306:594 Mol Cell Biol 1984; 4:1638 EMBOJ 1983;2:1633 tel:Airman, Mamm Genome 1991; 1:206 EMBOJ 1992; 11:527 Genes & Development 1990; 4:2319 J Virol 1989; 63:1763 Differentiation 1990; 42:160 J Biochem 1990; 108:785 ref:Watanabe, J Biochem 1991; 109:828 Genomics 1991; 11:828 ref:King, Genomics 1991; 11:273 refiMet~aranta, BBA 1991; 1089:241 ref:Metsaranta, J Biol Chem 1991; 266:16862 Nucl Acid Res 1986; 14:6765 DNA 1987; 6:149 PNAS 1985; 82:2024 Biochemistry 1987; 26:8683 Biochemistry 1987; 26:8683 J Biol Chem 1988; 263:6791 J Biol Chem 1989; 264:14011 ref:Domalik, Mol Endocrinol 1991; 5:1853 ref:Domalik, Mol Endocrinol 1991; 5:1853 ref:Domalik, Mol Endocrinol 1991; 5:1853 J Biol Chem 1989; 264:1305 ref:Domalik, Mol Endocrinol 1991; 5:1853 ref:Johnston, Mol Cell Biol 1989; 9:935 ref:Johnston, Mol Cell Biol 1989; 9:935 Somatic Cell Mol Genet 1984; 10:377 J Cell Biol 1989; 109:775 J Cell Biol 1989; 109:775 PNAS 1983; 80:3020 Genetics 1990; 125:431 ref:Meruelo, Immunogenetics 1987; 25:361 ref:Hogarth, Immunogenetics 1987; 25:21 Mamm Genome 1991; 1:57 Genetics 1985; 110:123 PNAS 1983; 80:3020 ref:Duncan, Mol Cell Biol 1988; 8:2705 ref:Huppi, Immunogenetics 1988; 27:215 ref:Blankenhorn, Genetics 1988; 119:687 J Biol Chem 1989; 264:4679 Mol Cell Biol 1990; 10:5244 ref:Moen, Mamm Genome 1991; 1:217 refiAdolph, Cytogenet Cell Genet 1989; 52:177 ref:Johnston, Mol Cell Biol 1989; 9:935 ref:Hearne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 PNAS 1988; 85:9576 Nature 1987; 330:537 ref:Eicher, Mamm Genome 1991; 1:57 Cytogenet Cell Genet 1989; 50:137 Nature 1981; 293:198 refiAdolph, Cytogenet Cell Genet 1988; 47:189 Mamm Genome 1991; 1:57 Nature 1980; 286:222 EMBO J 1989; 8:3327 Nature 1986; 320:328 ref:Rabin, PNAS 1986; 83:9104 EMBO J 1986; 5:2209 ref:Singh, PNAS 1991; 88:10706 ref:Hearne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

389

Table 3. Continued. Chr Symbola

Locus Name

15

Hox-3.1

homeobox-3, gene 1

15

Hox-3.2

homeo box-3, gene 2

15

Hox-3.3

homeobox-3, gene 3

15

Hox-3.4

homeo box-3, gene 4

15 15 15

Hox-3.7 Hox-3.8 Il2rb

homeobox-3, gene 7 homeobox-3, gene 8 interleukin-2 receptor, ~ chain [p70 subunitl

15

Ius-3

insulin I or insulin pseudogene (either Ins-1 or Ins-3)

15

]5 15 15 15

Krt-2

Krt-2,6 Krt-2,8 Krt-2ps Ly-6

keratin gene complex-2 [Endo-A]

keratin gene complex-2, gene 6 keratin gene complex-2, gene 8 cytokeratin Endo A, pseudogene lymphocyte antigen-6.1 allele

~

RFLVC C c n ~ t

~m31,~.m32 pro31.1, pm31.1e Hox-3.1 eDNA + m32-9 Hox-3.2 eDNA clone c16 Hox-6 genomic Hox-3.3/3.4 genomic Hox-6.1 eDNA Hox-6 genomic clone 55t + clone 13h * I12rb probe kMIL2R~-26, klVIIL2R~-21 ~MIL21~-12, pMIL2R~-22 pMIL2R~-36 [R] pI19 + [HI phins214 + pK4.2(bl) +

Breier Breier Watanabe Breier

pK435(al)

Meruelo

p6-94 pE8 M22832 (microsat) (microsat) pKA56 RecXVI clone a l pmal-2, genomie A21p Ck8 genomie clone a2 pKLy6.1-2R

+

+ §

+ + + + + +

pKLy6.1-2D pKLy6.1-2 E +

Cluster Cluster Cluster Cluster

A cosmids (includes Ly-6A.2) B cosmids (includes Ly-6C.2) C cosmids C cosmids

15

Ly-6.2

lymphocyte antigen-6.2 allele

15

Ly-6C

lymphocyte antigen-6C

15 Mlvi-2

Moloney-MuLV integration site-2

15 15

Mlvi-4 "Mns-15"

Moloney-MuLV integration site-4 minor satellite Chr 15 (centromeric)

15

Mpmv-30

pKLy6.1-5W NOD r NOD r 5' probe c47, c66, c~4, c5, c72, c74, c77, c62, c50, c~8 c83, c71, c20, c58, c54 c8, c68, c29, c27, c69 c63 B18,B28 kcRH-11 ~RH-12 B17,B34 clone 24 pTS10, pTS6, kC1228 pTS10

+

+

pLE18, [R] pM3F_JB pMR150

modified polytmpic murine leukemia virus-30 JS-4 JH 15 "Ms7-1-2-PI" minisatellite 7-1-2-P1 (human RB1) p68RS2.0 15 '2YIs7-1-3-P2" minisatellite 7-1-3-P2 (human RB1) p68RS2.0 15 "Ms7-2-4-P1" minisatellite 7-2-4-P1 (human RB1) p68RS2.0 15 ~Ms7-2-6-P2" minisatellite 7-2-6-P2 (human RB1) p68RS2.0 15 ~Ms7-3-4-Pl" minisatellite 7-3-4-P1 (human RB1) p68RS2.0 15 "Ms7-3-6-P2" minisatellite 7-3-6-P2 (human RB1) p68RS2.0 15 '2Vls7-3-9-P2" minisatellite 7-3-9-P2 (human RB1) p68RS2.0 15 Mtv-36 m a m m a r y tumor virus locus-36 MMTV8-21 15 Myc myelocytomatosis oncogene ~.E1, kST4-2, XST4-1, :kST4-3

+ + + + + + + + +

pMI04BH +

Erselius

Schughart Sharpe Gaunt Sharpe

Sharpe Singh Singh Campbell Kono Kono Kono Lomedieo co:P Lomedico Bell Saunders Meruelo 5-Compton Morita co:JA Todd co:JA Todd Ouellet Vasseur Vasseur Finch co:M Nozaki Vasseur LeClair LeClair co:LeClair co:LeClair co: Bothwell Eicher LeClair LeCI air Eieher LeC] air Philbrick Philbrick eo:D Meruelo co:D Merue]o co:D Meruelo eo:D Meruelo co:D Meruelo Pal free Reiser Reiser Pal free Bothwell Tsiehlis Mueenski co:H Hameister Tsichlis Voliva co:VM C h a p m a n eo:ND Hastie Frankel co:W Frankel co:T Dryja eo:T Dryja co:T Dryja eo:T Dryja co:T Dryja co:T Dryja co:T Dryja eo:JE Majors Cory Cory Shen-Ong Eicher

Ref~mcee

EMBO J 1986; 5:2209 EMBO J 1986; 5:2209 Biochem Genet 1990; 28:257 EMBO J 1988; 7:1329 Development 1990; 110:629 Genomies 1989; 5:76 Development 1988; 102:397 Development 1990; 109:329 Development 1988; 102:397 Development 1988; 102:397 PNAS 1991; 88:10706 PNAS 1991; 88:10706 Genomics 1992; 12:179 PNAS 1990; 87:1806 PNAS 1990; 87:1806 PNAS 1990; 87:1806 Cell 1979; 18:545 ref.'Meruelo, Immunogeneti~z 1987; 25:361 Diabetes 1984; 33:176 Genomics 1990; 8:525 Immunogenetics 1987; 25:361 Immunogenetics 1987; 25:361 unpublished, Jackson Lab Gene 1988; 68:109 ref:Hearne, M a m m Genome 1991; 1:273 Montagutelli, M a m m Genome 1991; 1:255 Gene 1988; [email protected] PNAS 1985; 82:1155 PNAS 1985; 82:1155 Carcinogenesis 1991; 12:1519 ref:Tamai, Gene 1991; 104:169 PNAS 1985; 82:1155 EMBO J 1986; 5:3227 PNAS 1987; 84:1638 tel:Duncan, Mol Cell Biol 1988; 8:2705 ref:Huppi, Immunogenetics 1988; 27:215 ref:Meruelo, Immunogenctics 1987; 25:361 M a m m Genome 1991; 1:57 EMBO J 1986; 5:3227 EMBO J 1986; 5:3227 Genetics 1990; 125:431 EMBO J 1986; 5:3227 EMBO J 1990; 9:2485 EMBO J 1990; 9:2485 ref:Kamiura, Genomies 19921; 12:89 ref:Kamiura, Genomics 1992; 12:89 ref:Kamiura, Genomics 1992; 12:89 ref:Kamiura, Genomics 1992; 12:89 ref:Kamiura, Genomics 1992~ 12:89 Immunogenetics 1987; 26:389 PNAS 1988; 85:2255 FNAS 1988; 85:2255 J Immunol 1988; 140:305 J Immtmol 1988; 140:2815 Mol Cell Biol 1984; 4:997 J Virol 1988; 62:839 refiAdolph, Cytogenet Cell Genet 1988; 47:189 J Virol 1990; 64:2236 Nucl Acid Rcs 1983; 11:8847 ref:Broceoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1983; 11:6965 Genetics 1990; 124:221 ref:Gecstein, Cell 1990; 63:537 refiJulier, PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4586 ref:Julier, PNAS 1990; 87:4585 refiJulier, PNAS 1990; 87:4585 ref.'Julier, PNAS 1990; 87:4585 ref-Julier, PNAS 1990; 87:458~; ref'~ulier, PNAS 1990; 87:4585; ref:Siraetma, Genetics 1991; 127:169 EMBOJ 1985; 4:675 EMBO J 1985; 4.'675 Cell 1982; 31:443 M a m m Genome 1991; 1:57 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

390 Table 3.

Continued.

Symhda

15

Myc

~

Name

Probe b

myelocytomatosis oncogene

RFLVc Contactd

pI04E~ pmyc pMcmyc54 (e~con 1)

exon2-Myc pSVc-mycq

+

IV] v-myc pUCc-myc Ryc7.4 [H] Myc 3' exon

15

Niard

15

Pdgfb

nomimmunoglobulin r e a r r a n g i n g D N A sequence (near Myc) platelet-derivedgrowth factor

clone V59 pSP65-C-myc, V-LMC-41 cmyc plasmid MMMYCE12 (microsat) + (microsat) + pa25BH3.4 pSSVll (Oncor) p3040 (Oncor)

+ + +

pc-sis pSP65-v-sis [H] Sis c D N A 15 15 15

Pfk-4 ple Pmv-17

phosphofructekinase- 4 perinatal lethality transgene polytropic murine leukemia virus-17

PFK cDNA c-myc genomic probe JS-5 JS-5, MCF100 pXenv EcoB/S B65.5PV2

+ + + + + + +

15 Pmv-36 15 Pmv-42 15 Pmv-48 15 Pmv-50 15 Pmv-54 15 Prph

15

15

Pva

Pvt-I

polytropic murine polytropic murine polytropic murine polytropic murine polytropic murine peripherin parvalbumin

leukemia leukemia leukemia leukemia leukemia

virus-36 virus-42 virus-48 virus-50 virus-54

plasmacytoma variant translocation-i

JS-5 JS-5 JS-5 JS-5, MCFIOO

JS-5 [R] Prph cDNA [R] clone 9f

+ + + + +

[R] PV9f mpv + cW28, cW22, cW18.1 cW24.1, cW18.2, cW17 %W, kA4-1, kA4-2 cA4-5, cA4-3, cA4-12 M1, cW.28, cA4.5, cA4.3 Probe B PmbeE pTS25E/P

15

Rarg

retinoic acid receptor T

pTS26P/P, kCIC31A pTS26 pBSS.1, pE/B7 pBSS.5, pBS27A clone Pvt-l-1 pvt-lb, pvt-le [R] pMo-lC, [R]fragment 4 mRART-cDNA

15

Rpl30

ribosomal protein L30

rpL30-1

15 15

Sis Spl-1

(withdrawn, = Pdgtb) Spl trans-acting transcription factor-1

I.~)-I3

[HI pSpl-1 pMusSp1-11

+ +

Refea~ncee

co:M Cole rof:Mucenski, J Virol 1988; 62:839 Siracusa Genetics 1991; 127:169 co:LW Staton,G Childs reflRajan, J Immunol 1990; 145:1598 co:KB Marcu refiStanton, Nature 1983; 303:401 Nature 1986; 319.780 Zimmerman co:K Marcu refiHuppi, Immunogenetics 1988; 27:215 co:KB Marcu ref:Duncan, Mol Cell Biol 1988; 8:2705 co:KB Marcu ref:Blankenhorn, Genetics 1988; 119:687 Meruelo Immunogenetics 1987; 25:361 H Axelson Oncogene 1991; 6:2263 Watanabe Biochem Genet 1990; 28:257 Nature 1983; 304:596 Land Johnson Exp Cell Res 1990; 187:69 Schoenenberger EMBO J 1988; 7:169 co:M Shibuya, T Yamaoto ref:Todokoro, BBRC 1986; 135:1112 co:R Jaggi ref:Schoenenberger, EMBO J 1988; 7:169 Marcu PNAS 1983; 80:519 Rappold EMBO J 1984; 3:2951 Adolph Cytogenet Cell Genet 1987; 44:65 Almendral Mol Cell Bioi 1988; 8:2140 Collart J Immunol 1987; 139.949 co:J Sedivy ref:Boyle, Genomics 1992; 12:106 co:JA Todd ref:Hearne, M a m m Genome 1991; 1:273 Montagutelli M a m m Genome 1991; 1:255 PNAS 1983; 80:519 Marcu co:KB Marcu ref:Knight, Mol Cell Probes 1990; 4:497 Meruelo Immunogenetics 1987; 25:361 Duncan Mol Cell Biol 1988; 8:2705 Huppi Immunogenetics 1988; 27:215 Kozak Science 1983; 221:867 Collart J Immunol 1987; 139.949 Groffen J Exp Med 1983; 158:9 Adolph Cytogenet Cell C-enet 1987; 44:65 Ashley Cytogenet Cell Genet 1987; 46:573 Beier Genomics 1989; 4:498 Frankel J Virol 1989; 63:3810 Frankel M a m m Genome 1992; 2:110 co:MA Martin ref:Wejman, J Virol 1984; 50:237 Hogarth Immunogenetics 1987; 25:21 Meruelo Immunogenetics 1987; 25:361 Meruelo Immunogenetics 1987; 25:361 Rossomando Immunogenetics 1986; 23:233 Frankel J Virol 1989; 63:3810 Frankel J Virol 1989; 63:3810 Frankel M a m m Genome 1992; 2:110 Frankel M a m m Genome 1992; 2:110 Frankel M a m m Genome 1992; 2:110 co:LA Greene ref:Pendelton, Genomics 1991; 9:369 Berchtold PNAS 1985; 82:1414 Kluxen E u r J Biochem 1988; 176:153 co:Hameister re,Adolph, Cytogenet Cell Genet 1989; 52:177 Zuhlke Genet Res 1989, 54.'37 Cory EMBO J 1985; 4:675 Cory EMBO J 1985; 4:675 Cory EMBO J 1985; 4:675 Cory EMBO J 1985; 4:675 Villeneuve Mol Cel Biol 1986; 6:1834 co:S Cory refiAdolph, Cytogenet Cell Genet 1988; 47:189 Graham Nature 1985; 314.'740 Tsichlis J Virol 1985; 56:258 Mucenski J Virol 1988; 62:839 Kozak Mol Cell Bid 1985; 5:894 co:H Hameister refiAdolph, Cytogenet Cell Genet 1988; 47:189 Tsichlis PNAS 1989; 86:5487 Tsichlis PNAS 1989; 86:5487 Huppi PNAS 1990; 87:6964 H Axelson Oncogene 1991; 6:2263 Jolicoeur J Virology 1985; 56:1045 co:P Chambon refiZelent, Nature 1989; 339:714 Mattei Genomies 1991; 10:1061 Wiedemann Mnl Cell Biol 1984; 4:2518 Wiedemann Somatic Cell Mol Genet 1987;13:77 co:J Kadonaga Softer

ref:Saffer, Genomics 1990; 8:571 Genomies 1990; 8:571 C o n t i n u e d on next p a g e

J.T. Eppig: Clones a n d Probes

391

Table 3. Continued. (Ynr Sym/~a

15

15 15

15

15 15 16 16 16

16 16 16 16 16 16 16 16

16 16 16 16 16

Spt

sw Tgn

~

Name

p~e b

RFLVc Centa~d

salivary protein cluster (Spt-1)

pBR MSM AKR A3.1

+

(Spt-1) (Spt-2)

pSMG751 pSM 443 pBR MSM DBA 2B10.1

+

swaying (allele of Wnt-1) thyroglobulin

[R]pRT27.15,[R]pRT36.1 [R] pRT57 " + " + +

Dickinson Dickinson Windass Dickinson Dickinson

co:R DiLauro Musti co:R DiLauro Either Eicher co:R DiLauro " + co:R DiLauro Writ-1 wingless-related MMTV integration site-1 pMT2.5 Nusse (ex Int-1) 1-Nusse + co:Susse Fung + Thomas $6~1 + co:H Varmus probe C & D Nusse co:Nusse clones: 2, 26, 17A, 104A Fung clone 26 Jakobovits pint2.5 co:H Varmus probe c co:H Varmus pint-lE, pint-lE5 Wilkinson junct frag tumor 102,604, Nusse junct frag tumor 35, 17 Nusse Wnt-1 eDNA Gavin MMINT1 (microsat) + co:JA Todd Wnt-7B wingless-related MMTV integration site-7B Wnt-7B eDNA Gavin Wnt-7b genomic Gavin Xmv-37 xenotropic murine leukemia virus-37 JS-6~/S-1O + Frankel Akv-2 (withdrawn, = Emv-12) Apod apolipoprotein D [H] apoD eDNA + co:R Lawn App amyloid 13 (A4) percursor protein unnamed Philip [H] clone B2.3 Robakis + Reeves pDS10.1 + Reeves + Reeves pMAZ11,pMAZ61 Yamada [H] FB68L, [H] HL124 + Cheng [H] FB68L + co:SDM Brown App probe co:N Irving CD-1 cDNA Fukuchi BPP770,BPP751,BPP695 Yamada APP695,APP751,APP770 Fisher APP695, APP cDNA/ICR, co:F vanLeuven APP cDNA/B6CBAF1 co:F vanLeuven Ck-4 creatine kinase-4 [H] pCPK-B Mariman + co:ECM M a r i m a n "D16?" DI6 segment, nonstringent hybridization pYMT2/B Bishop "D16H22" DNA segment, Chr 16, H22 cosmid H22 Boyle "D16McCI" DNA segment, Chr 16, McClelland-1 AP-PCR oligo KB + co:M McClelland D16Smh6 DNA segment, Chr 16, St. Mary's Hosp-6 D16Smh6 + co:SDM Brown (AC)n PCR probe + co:SDM Brown D16Smh250 DNA segment, Chr 16, St. Mary's Hosp-250 PCR250 + co:SDM Brown + co:SDM Brown D16Smh580 DNA segment, Chr 16, St. Mary's Ho6p-580 PCR560 + co:SDM Brown IY21S16h DNA segment, Chr 16, human D21S16 [H] pGSE9 + Cheng + Reeves + co:GD Stewart [H] D21S16 + co:SDM Brown D21S52h DNA segment, Chr 16, human D21S52 [H] 511-1H/511-2P + Cheng D21S58h DNA segment, Chr 16, human D21S58 [H] 524-5P § Cheng dw dwarf (see Pit-l) Emv- 12 endogenous ecotropic MuLV-12 AKR 1D242 5-Epstein Ets-2 E26 avian leukemia oncogene-2, 3' domain pl.27 2-Sherman o Reeves co:N Irving PH1.03 + Reeves + Reeves + eo:JD Gearhart + co:RH Reeves + Reeves § co:DK Watson

t~enmcee

Biochem Genet 1989; 27:613 Mol Bioi Evol 1989; 6:80 Nucl Acid Res 1984; 12:1361 Biochem Genet 1989; 27:613 Mol Bioi Evol 1989; 6:80

refiTaylor, PNAS 1987; 84:1986 PNAS 1986; 83:323 reflTaylor, PNAS 1987; 84:1986 Genetics 1990; 125:431 M a m m Genome 1991; 1:57 refiAdolph, Cytogenet Cell Genet 1989; 52:177 ref.'Siracusa, Genetics 1991; 127:169 Nature 1964; 307:131 refiOoyen, Cell 1984; 39:233 ref:Bruisten, Genetics 1989; 121:795 Mol Cell Biol 1985; 5:3337 Cell 1991; 67.@69 ref:Saffer, Genomics 1990; 8:571 Nature 1984; 307:131 ref:Adolph, Cytogen Cell Gene 1987; 44:65 Mol Cell Biol 1985; 5:3337 PNAS 1986; 83:7806 ref:Meruelo, Immunogenetics 1987; 25:361 refiPathak, JNCI 1987; 78:327 Cell 1987; 50:79 Mol Cell Biol 1990; 10:4170 Mol Cell Biol 1990; 10:4170 Genes & Development 1990; 4:2319 ref:Aitman, M a m m Genome 1991; 1:206 Genes & Development 1990; 4:2319 Genes & Development 1990; 4:2319 J Virol 1989; 63:1763 ref:Warden, Genomics 1992; 12:851 Am J H u m Genet 1987; 41:A233 PNAS 1987; 84:4190 Mol Brain Res 1987; 2:215 Genomics 1989; 5:522 Genomics 1990; 8:141 BBRC 1987; 14~.665 PNAS 1988; 85:6032 tel:Irving, Genomics 1991; 9:386 ref:Knight, Mol Cell Probes 1990; 4:497 Nucl Acid Res 1989; 17:5396 BBRC 1989;, 156:906 PNAS 1991; 88:1779 raf:deStrooper, BBA 1991; 1129:141 ref:deStrooper, BBA 1991; 1129:141 Genomics 1987; 1:126 ref:Cho, M a m m Genome 1991; 1:30 Nucl Acid Res 1987; 15:2959 Genomics 1992; 12:106 tel:Welsh, Nucl Acid Res 1991; 19:5275 tel:Irving, Genomics 1991; 9:386 tel:Irving, Genomies 1991; 11:'.679 refiIrving, Genomics 1991; 11:679 ref.'Irving, Mouse Genome 1991; 89:854 raf:Irving, Genomics 1991; 11:679 PNAS 1988; 85.~032 Genomics 1990; 8:141 ref:Colombo, M a m m Genome 1992; 2:130 ref:Irving, Genomics 1991; 9:386 PNAS 1988; 85.~032 PNAS 1988; 85:6032 Immunogenetics 1984; 19:527 FNAS 1983; 5465 Cytogenet Cell Genet 1987; 44:76 tel:Knight, Mol Cell Probes 1990; 4:497 Cytogenet Cell Genet 1987; 44:76 Genomics 1990; 8:141 ref:O'Hara, Mol Brain Res 1988; 4:283 ref:Siracusa, Genetics 1991; 127:169 Genomics 1989; 5:522 tel:Colombo, M a m m Genome 1992; 2:130 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

392 Table 3. Continued. Chr Syrnlmla

16

Ets-2

LocusName

Probeb

E26 avian leukemia oncogene-2, 3' domain Ets-2 genomic [H] H33 pA3

co:SJ O'Brien co:SJ O'Brien Watson co:D Watson unnamed (H33 homol) + W a t s o n [H] H33 Watson + Cheng ETS2 + co:SDM Brown [H] Gap43 cDNA Kosik GAllb + Reeves + co:RH Reeves [R] Gap43 cDNA + co:R Reeves Gas-4 cDNA-1 Schneider Gas-4 cDNA-2 + co:P D'Eustachio [H] HMG14 cDNA Pash Hmg14 cDNA-1, Landsman H m g l 4 cDNA-2 Landsman Htf9 genomic + co:P Lavia pL9.3, pLg.2, clones 16, 19 co:P Lavia pL9.5, pL9.2 co:P Lavia pABk -1 Bothwell Miller pABMI-1 Francke pCM-4E + co:Epstein + co:R Epstein MOPC104E + Scol~ + Reeves + co:R Reeves CM probe (MOPC104E) + eo:JD Gearhart p~ii-i Bothwell pki-13 Bothwell Igl-1 probe + co:R Reeves Igl-5-5'genomic, Kudo Igi-5-3' genomic, Igl-5 cDNA Kudo pABI-1 Kindt KA9,KA11,KH5 Miller pEJ3-C k M il I er Bothwell pAB-kll Alt clone 9A8 Hilbert unnamed co:Bothwell Mami Igi-cl probe + co:B Blomberg Igl-M cDNA D'Eustachio + co:K Huppi pC1 H Axelson unnamed co:Hozumi Mami V~2 Dildrop Igl-MI cDNA D'Et~stachio H Axelson pX-II-1 + Hilbert clone 8 Mami clone 71-2 + Mami pCLSs + Mami clone 9A8 Hilbert unnamed (J2, J4) Blomberg Mami V%l (J1), Vk2 (J2) Dildrop Igl-CP4 12-18 cDNA co:J-C Jaton IgI-CP5 B5-3 cDNA co'J-C Jaton Igl-CP5 A23-3 cDNA co:J-C Jaton Igl-CP5 A21-1 cDNA co:J-C Jaton Igl-CP4 9-9 cDNA co'~l-C Jaton Igi-CP3 23-24 cDNA co~-C Jaton clone 9A8 Hilbert pAB-MI Alt Igl-CP4 12-18 cDNA co:J-C Jaton Igl-CP5 B5-3 cDNA co:J-C Jaton Igl-CP5 A23-3 cDNA co:J-C Jaton Igl-CP5 A21-1 cDNA co:J-C Jaton Igl-CP4 9-9 cDNA co:J-C Jaton Igl-CP3 23-24 cDNA co:J-C Jaton Ig3,03~., Ig99k, Ig13~. co:S Tonegawa clone 9A8 Hilbert Ig99X co:T Honjo "

16 Gap43

growth accentuating protein 43

16

Gas-4

growth arrest specific-4

16

Hmg14

high mobifity group protein 14

16 16 16 16

Htf9 Ht~D HttD Igl-1

HpalI tiny fragment locus 9 HpaII tiny fragment locus-9a HpalI tiny fragment locus-9c immunoglobulin ~. chain, cluster 1

16

Igl-5

immunoglobulin ). chain-5

16

Igl-C

immunoglobulin ~. chain, constant

16

Igl-C 1

immunoglobulin ~. chain, constant-1

16

Igl-C2

immunoglobulin k chain, constant-2

16 16 16

Igl-C2-3 Igl-C4 Igl-C5

immunoglobulin k chain, constant-2,3 immunoglobulin k chain, constant-4 immunoglobulin k chain, constant-5

16 16

Igl-D Igl-J

immunoglobulin k chain, diversity immunoglobulin k chain, J region

Igl-V

i m m u n o g l o b u l i n k chain, variable

RFLVc C o n t ~
+

Refeg~,c~e

ref:Wataon, PNAS 1986; 83:1792 ref:Wat~on, PNAS 1986; 83:1792 PNAS 1988; 85:7862 ref:Reeves, Genomics 1989; 5:522 PNAS 1986; 83:1792 Anticancer Res 1986; 6:631 PNAS 1988; 85:6032 ref:Irving, Genomics 1991; 9:388 Neuron 1988; 1:127 Genomics 1990; 8:141 ref:Irving, Genomies 1991; 9:386 ref:Bressan, Gene 1991; 103:201 Cell 1988; 54:787 ref:Colomb% M a m m Genome 1992; 2:130 PNAS 1990; 87:3836 Nucl Acid Res 1990; 18:5311 Nucl Acid Res 1990; 18:5311 ref:Bressan, Gene 1991; 103:201 ref:Bressan, Gene 1991; 103:201 ref:Bressan, Gene 1991; 103:201 Nature 1981; 290:65 PNAS 1981; 78:3829 Cytogenet Cell Genet 1982; 33:267 Immvnogenetics 1986; 23:78 ref:Bosma, Immunogenet 1989; 29:54 Nature 1982; 300:757 Cytogenet Cell Genet 1987; 44:76 ref:Irving, Genomies 1991; 9:386 ref:O'Hara, Mol Brain Res 1988; 4:283 Nature 1981; 290:65 Nature 1981; 290:65 ref:Bressan, Gene 1991; 103:201 Genomies 1987; 1:277 Genomics 1987; 1:277 E u r J Immunol 1986; 15:535 PNAS 1981; 78:3829 PNAS 1981; 78:3829 Nature 1981; 290:65 Cell 1981; 27:381 J Immunol 1988; 140:4364 Nature 1981; 290:65 J Immunol 1987; 138:3980 tel:Epstein, Immunogenetics 1984; 19:527 J Exp Med 1981; 153:793 ref:Warden, Genomies 1992; 12:851 Oncogene 1991; 6:2263 ref:Alonso, J Immunol 1985; 135:614 J Immunol 1987; 138:3980 E u r J Immunol 1987; 17:731 J Exp Med 1981; 153:793 Oncogene 1991; 6:2263 J Immunol 1988; 140:4364 J Immunol 1987; 138:3980 EMBO J 1988; 7:117 EMBO J 1988; 7:117 J Immunal 1988; 140:4364 PNAS 1982; 79:530 J Immunol 1987; 138:3980 E u r J Immunol 1987; 17:731 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Iromunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Rcininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 J Immunol 1988; 140:4364 Cell 1981; 27:381 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:318 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Reininger, J Immunol 1987; 138:316 ref:Honjo, Cell 1979; 18:559 J Immunol 1988; 140:4364 ref:Kataoka, J Biol Chem 1982; 257:277 C o n t i n u e d on next p a g e

393

J.T. Eppig: Clones and Probes Table 3. Continued, Chr SymhJa

16

Igl-V1

LocusName

immunoglobulin % chain, variable-1

Probeb

RFLVc Contactd

Vkl Igl-M eDNA MOPC 104E eDNA

16

Igl-V2

immunoglobulin ~. chain, variable-2

V)~2 pV2

pEZl-V~ done 9A8 MOPC 104E cDNA

Igl-MI e D N A pZl21

16

Igl-VpreB 1

16

Igl-Vx

immunoglobulin ~.x variable chain

16

Igll

immunoglobulin ~. chain like

16 16

Int-53 Ltrm-2

16

"Mns- 16"

mammary tumor integration site-53 LTR mink cell focus-forming murJne leukemia viral locus-2 minor satellite Chr 16 (centromeric)

16

Mpmv-17

16

Mtv-6

16 16

Mtv-37 Mx-1

Y31 30X2, Y31 7pBS, 7pB12, 7pB18, 7pB28, pZ183-1a pZ183 X~IT53/1, p53/I CI-3-LTR

pMRiS0

modified polytropic murine leukemia virus-17 JS-4 JS-4 mammary tumor virus locus-6 unnamed MMTV-LTR MMTV eDNA E-P MTV-GR40 ev-8, pvc-28 MMTV e D N A or D N A MMTV8-21,MMTV8-29 M M T V 8-21 MMTV 8-29 MMTV8-21,MMTV8-29 pTZ18R-ORF MMTV5', MMTV3' mammary tumor virus locus-37 MMTV8-21 myxovirus (influenza virus) resistance-1 pMx34, pMx41 pMx34 pMx34 frag

16 16

Mx-2 Pgk-lpsl

pMx41 pCBA Mxl Mx-1 eDNA Mx2.3 myxovirus (influenza virus) resistance-2 Mx-2 eDNA phosphoglycerate kinase-1 pseudogene 1 B24

16 16

Pim-lrs2 Pit-1

P~m-1 oneogene related sequence-2 pituitary specific transcription factor-1

Pmv-14 Pmv-16 Pmv-35 Prm- 1

polytropic murine leukemia virus-14 polytropic murine leukemia virus-16 polytropic murine leukemia virus-35 protamine- 1

genomic clone VI

44-

+ + + + +

+ + + + + + + + + +

Hug + + +

+

~beS Pit-1 eDNA (PCR) [R] Pit-1 probe JS-5 JS-5 JS-5 pmPl-1, raP1 pmPl-1

+ + + + +

+ 44+

mP1 + 4-

pmP1-P3.2

co:Simon Dildrop D'Eustachio Hilbert Scott co:Scott co:Simon Dildrop H Axelson Miller Bothwell Soott co:Scott Scott co:Scott D'Eustachio Kudo co:A Kudo Sanchez Sanchez Kudo Kudo Sakaguchi Schuermann Rapp Eicher Veliva eo:VM Chapman co:ND Hastie Frankel Frankel Callahan co:Reeves Michalides Michalides co:Michalides co:J Ball, J Majors Majors Eicher Eicher Lee co:JE Majors co:G Peters co:JE Majors co:Hailer Staeheli Reeves co:SDM Brown Staeheli Reeves Reeves Staeheli Adra co: N Ellis Potten Hilkens Camper co:M Rosenfeld Frankel Frankel Frankel Kleene Hecht Reeves Reeves co:JD Gearhart co:R Reeves Kleene Johnson co:SDM Brown co:NB Hecht co:R Palmiter

Refe~mcee

ref:Picard, PNAS 1983; 80:417 Ettr J Immtmol1987; 17:731 J ExpMed 1981;153:793 J Immunol1988; 140:4364 Nature 1982; 300:.757 ref:Hilbert, J Immunol 1988; 140:4364 ref:Bothwell, Nature 1981; 290:65 Eur J Immtmol 1987; 17:731 Oncogene 1991; 6:2263 PNAS 1981; 78:3829 Nature 1981; 290:65 Nature 1982; 300.757 ref:Hilbert, J Immunol 1988; 140:4364 Nature 1982; 300:.757 ref:Hilbert, J Immunol 1988; 140:4364 J Exp Meal 1981; 153:793 EMBO J 1987; 6:2287 ref:Okabe, E u r J Immunol 1992; 22:31 PNAS 1987; 64.<9185 J Immunol 1990; 144:2816 E M B O J 1987;6:103 E M B O J 1987;6:103 E M B O J 1986;5:2139 Virology 1987; 156:229 J Virol 1983;45:740 Genetics 1990; 125:431 N u d Acid Res 1983; 11:8847 rof:Broccoli,Cytogenet Cell Genet 1990; 54:182 ref:Pietras,N u d Acid Res 1983; 11:6965 Genetics 1990; 124:221 M a m m Genome 1992; 2:110 J Virol 1984; 49:1005 Cytogenet Cell Genet 1987; 44:76 Virology 1985; 142;278 Virology 1985; 142;278 ref:Meen, M a m m Genome 1991; 1:217 ref:Maclnnes, Virology 1984; 132:12 Nature 1981; 28~.253 Genetics 1990; 125:431 Genetics 1990; 125:431 J Virol 1990; 64:4568 ref:Pullen, J Exp Med 1992; 175:41 ref:Fairchild, Immtmogeneties 1991; 34:227 ref:Siractma, Genetics 1991; 127:169 refi Staeheli, Cell 1986; 44:147 Mol Cell Biol 1988; 8:4518 J Virol 1988; 62:4372 rof:Irving, Genomics 1991; 9:386 J Virol 1986; 56:967 Mol Cell Biol 1988; 8:3065 Genomics 1989; 5:522 Genomics 1990; 8:141 Mol Cell Biol 1988; 8:4524 Somatic Cell Mol Genet 1988; 14:69 ref:Irving, GenomJcs 1991; 9:386 Gene 1988; 71:461 Somatic Cell Mol Genet 1986; 12:81 Genomics 1990; 8:536 ref:Warden, Genomics 1992; 12:851 J Virol 1989; 63:3810 J Virol 1989; 63:3810 J Virol 1989; 63:3810 Devel Biol 1983; 98:455 Somatic Cell Mol Genet 1986; 12:203 Cytogenet Cell Genet 1987; 44:76 J Heredity 1989; 80:442 refiO'Hara, Mol Brain Res 1988; 4:283 rofiBressan, Gene 1991; 103:201 Biochemistry 1985; 24:719 Biochem Biophys Acts 1988; 950:45 tel:Irving, Genomics 1991; 9:386 ref:Gora-Maslak, Mouse Genome 1991; 89:852 ref:Willison, Genet Rcs 1990; 56:193 C o n t i n u e d on n e x t p a g e

394

J.T. Eppig: Clones and Probes

Table 3. Continued. Symbola

16

16

Prm-2

Smst

~

Name

Probeb

protamine-2

mP2-1,mP2-2

(5'flank of mP2 genomic)

mP2-FCD, mP2-EB H S A R 900

somatestatin

p1-16-13

RFLVc C~ntac~

~MST-17, pMST-15, pMST-1.4

16

Sod-1

superoxide dismutase-1, soluble

Smst genomic [H] pHSI-1-2.7 (called pghS7-2.7) SOD4.1 [H] pSGI-10 [H] pS61-10, [HI pS58-13 [H] pS61-10

16 Topl-ps2 16 Vpreb-1

[H] SOD1 clone Sod-1 cDNA topoisomerase 1, pseudogene-2 (may be on Chr 19) Top genomic pZl21 pre-B lymphocyte gene-1

16 16

Vpreb-2 Xmv-35

pre-B lymphocyte gene-2 xenotropic murine leukemia virus-35

16 17

Xmv-50 Bat-1

xenotropic murine leukemia virus-50 HLA-B associated transcript-1

7pB60, 7pBT0 JS-6+JS-10 JS-6+JS-10, XENO112 JS-6+JS-10, XENOII2 [HI BATI-I1

17

Bat~2

HLA-B associated transcript-2

[H] BAT2-5

17

Bat-4

HLA-B associated transcript-4

[H] BAT4-3

17

Bat-5

HLA-B associated transcript-5

[H] BAT5-1

17

Bf

complement component factor B

pBrnB2

+ + + +

+

+

+

+

17

Bkm-4

banded krait minor satellite DNA-4

17

C2

complement component-2

pmBfS/70, pmBf24 cesmids: D-7, D-12, cesmids: D-9, D-16, cesmids: D-24, D-6, cosmids: D-14 T459/A,W459/A, ccsmid 81 [D] pCS316 [H]pC2a-2a

+

~.M1 pC2-2,pC2-10 17

123

complement component-3

C4

complement component-4

(from AKR) (from FM strain)

(from DBA/I strain)

pMLC3-7, pMLC3-4 pMLC3-1 pMLC3-4 + pC412I, pC427A pFC4/10 k17A, ~.1 pDS 119,pG2.6,pDC 109,BH clone 9.2, clone 10.8 pFC4/5.4 kC4-2.2,kC4-3.13,kC4-2.14, kC4-2.3,kC4-3.25,kC4-2.4, kC4-3.21,%C4-3.15,%C4-2.6 pDC4r pBmS2, pBmS10 + +

(from B10.W7R)

pMC4/21 pMC4/7

+ + + + +

cesmid 16.2

Yelick Johnson Reeves Johnson Kleene Hocht co:Goodman Reeves co:SDM Brown co:JD Gearhart eo:JD Gearhart co:RH Reeves co:R Reeves co:A Ebel Shen, Rutter Lalley coiReeves co:JD Gearhart Cheng Lieman-Hurwitz Reeves Reeves co:Y Groner co:SDM Brown co:Y Groner Bewley Rettenberg Kudo Bauer Kudo Frankel Frankel Frankel Spies Snoek Spies Shock Spies Shock Spies Shock Sackstein Sackstcin Ishikawa Chaplin Chaplin Chaplin Chaplin Durbin Durbin co:KW Jones co:Woods Falus Ishikawa co:Fey co:Fey Lyon co:G Fey Sepich Nonaka Ogata Stavenhagen Levi-Strauss Nonaka Nonaka Nonaka Nonaka Nonaka Sackstein Gillet co:Tosi co:Tosi Levi-Strauss Golubric co:Levi-Strauss Stavenhagen

Refea~macee

Moi Cell Biol 1987; 7:2173 Biochem Biophys Acta 1988; 950:45 J Heredity 1989; 80:442 Biol Reprod 1991; 44:127 Devel Biol 1983; 98:455 Somatic Cell Mol Genet 1986; 12:203 J Biol Chem 1982; 257:1156 Cytogenet Cell Genet 1987; 44:76 refiIrving, Genomics 1991; 9:386 ref:O'Hara, Mol Brain Res 1988; 4:283 ref:O'Hara, Mol Brain Res 1988; 4:283 ref:Siracusa, Genetics 1991; 1271169 ref:Br~san, Gene 1991; 103:201 ref:Fuhrmann, Nucl Acid Res 1990; 18:1287 Science 1984; 2241168 Cytogenet Cell Genet 1987; 44:92 Cytogenet Cell Genet 1987; 44:76 ref:O'Hara, Mol Brain Res 1988; 4:283 PNAS 1988; 85:6032 PNAS 1982; 7912808 Genomics 1989; 5:522 Genomics 1990; 8:141 ref:El-Hage, Devel Genet 1990; 111149 refiIrving, Genomics 1991; 91386 ref:Wataon, PNAS 1986; 83:1792 Nucl Acid Res 1988; 16:2728 HGM1981; 111 191, abstr 2723 EMBO J 1987; 612267 EMBOJ 1988; 7:111 EMBO J 1987; 6:2267 J Virol 1989; 63:1763 Mamm Genome 1992; 2:110 Mamm Genome 1992; 2:110 PNAS 1989; 86:8955 Imrnunogenetics 1991; 341409 PNAS 1989; 86:8955 Immunogenetics 1991; 34:409 PNAS 1989; 86:8955 Immunogenetics 1991; 34:409 PNAS 1989; 86:8955 Immunogenetics 1991; 34:409 J Biol Chem 1985; 256:14693 Immtmogenetics 1984; 20:321 J Biol Chem 1990; 265:19046 PNAS 1983; 80:6947 PNAS 1983; 80:6947 PNAS 1983; 80:6947 PNAS 1983; 80:6947 Chromceoma 1989; 97:301 Chromcsoma 1989; 971301 refIKiel-Metzger, Nature 1984; 310:579 ref:Sackstein, Immunogenetics 1984; 20:321 J Immunol 1987; 138:856 J Biol Chem 1990; 265:19040 PNAS 1982 79:7619 PNAS 1982; 79:7619 Immunogenetice 1988; 27:375 ref:Nadeau, Genomics 1991; 9:78 PNAS 1985; 82:5695 PNAS 1984; 81:6822 J Biol Chem 1989; 264:16565 Cell 1988; 55:247 PNAS 1985; 82:1746 Immunol Rev 1985; 87:81 Immunol Rev 1985; 87:81 Immunol Rev 1985; 87:81 Immunol Rev 1985; 87:81 Immunol Rev 1985; 87:81 Immunogenetics 1984; 20:321 Immunogenetics 1988; 27:133 Phi Trans R Soc L 1984; 306:389 Phi Trans R Soc L 1984; 306:389 PNAS 1985; 82:1746 Immunogenetics 1984; 21:247 Vincek, Genomics 1989; 5:773 Mol Cell Biol 1987; 7:1716 Continued on next p a g e

395

J.T. Eppig: Clones and Probes Table 3. Continued. Cbr ~ a

17

C4

17

Cbs

17

Cdc2b

17

Ck-2

17

Crya- 1

17

Cyp21

17

D6S81Eh

17 "D 17?" 17 "D177" 17 D17Au3I 17 DI7Au3II 17 D 17Au9 17 "D 17H40" 17 D17Her139 17 D17Herlg0 17 D17Kenl 17 D17Leh9 17 D17Leh12 17 D17Leh23 17 D17Leh26 17 D17Leh27 17 D17Leh48

17

D17Leh54

17

D17Leh54M

17

D17Leh55

~

Name

complement component-4

Probeb

RFLV~ Omt~td

ccsmids: E-7, E-64, cosrnids: E-58, E-69 cesmids: F-4, F-13 ccernids: F-5, F-7 cesmids: E-42, E-15, cosmids: E-26 cesmids: ci-41, ci-21, cosmids: ci-40, el-4, cosmids: d-20, d-32 cosmids: ci-33, ci-38, cesmids: d-39, d-15 k18B, ~.17B [RIPS10

Chaplin Chaplin Chaplin Chaplin Chaplin Chaplin (w7 allele) Nakayama Nakayama Nakayama Nakayarna Nakayama Ogata cystathionine ~-synthase Kraus Stubbs Munke cell division cycle 2, homolog Chr 17 C1-BS Cisek + co:JL Corden CDCMm Spurt Th'ng creatine kinase-2 [H] pCPK-B Mariman + co:ECM Mariman a crystallin-1 pMctACr2 King + Skew Bucan + co:Skow (may=pMaA) + co:Skow " (calledpMaACrl) Stubbs " (called pMaACrl) Quinlan + Pilder pM aA + co:L Skow paACr2 + co:L Skow + co:L Skow + co:A Berns pMaACrl800, paA1501aCAT JaworskJ cytochrome P450, 21 steroid 21 hydroxylase pM21OH + co:Meo + co:Meo [HI pC2 I/3c + Gillet White + co:ATCC clone 3.3, clone 9.2 + Amor E-7, E-26 + Chaplin [B] pcBP-456c21-9 Yoshioka Gotoh DNA segment, Chr 17, human D6S81E cosmids 28.3, 19.1, 37.1 Wroblewski cesmid 35.1 Wroblewski Chr 17 specific cosl-2-4,cosl-2-4 derivative Kasahara Chr 17 specific MDMDB(B1) PCR Cox DNA segment, Chr I7, Austin-3I Au3 + Howard DNA segment, Chr 17, Austin-3II Au3 + Howard DNA segment, Chr 17, Austin-9 Au9 + Howard DNA segment, Chr 17, H40 cosmid H40 Boyle DNA segment, Chr 17, Hermann-139 Tu139 Hermann DNA segment, Chr 17, Hermann-190 Tulg0 Hermann DNA segment, Chr 17, Kensington-1 clone 46 + Mazarakis (t-type) pBsl3 + Mazarakis DNA segment, Chr 17, Lehrach-9 Tu9 + co:H Lehrach DNA segment, Chr 17, Lehraeh-12 Tul2 + co:H Lehrach D N A segment, Chr 17, Lehrach-23 Tu23 + co:H Lehrach DNA segment, Chr 17, Lehrach-26 2ba26 + co:H Lehrach DNA segment, Chr 17, Lehrach-27 Tu27 + co:H Lehrach DNA segment, Chr 17, Lehrach-48 (t) Tu48 + co:H Lehrach + Pilder Rohme + co:H Lehrach " (=T48) + co:H Lehrach Tu48(I0) + co:H Lehrach DNA segment, Chr 17, Lehraeh-54 Tu54 + co:H Lehrach " (=T54) + co:H Lehrach + Pilder DNA segment, Chr 17, Lehrach-54M p5411-R2 + co:Bucan p54q.5 + King + King DNA segment, Chr 17, Lehrach-55 Tu55 + co:H Lehraeh

Refetmcee

P N A S 1983; 80:6947 P N A S 1983; 80.~947 P N A S 1983; 80.~947 P N A S 1983; 80.~947 P N A S 1983; 80.~947 P N A S 1983; 80:6947 J Immunol 1987; 138:620 J Irnmunol 1987; 138:620 J Irnmunol 1987; 138:620 J Immunol 1987; 138:620 J Immunol 1987; 138:620 J Immuno11991; 147:2756 P N A S 1986; 83.'2047 Genomics 1990; 7:284 A m J H u m Genet 1988; 42:550 Nature 1989;, 33~679 rel%Jtmtiee, Genetics 1990; 125:855 Sequence 1990 (in press) Cell 1990; 63:313 Genomics 1987; 1:126 refiCho, Mamm Genome 1991; 1:30 Science 1982; 215:985 Genetics 1987; 116:107 Genes & Devel 1987; 1:376 Genetics 1985; 110:723 rel?Erhart, Genetics 1989; 123:405 Genomics 1990; 7:284 Genes & Devel 1987; 1:637 Genetics 1991; 129:237 ref:Henson, PNAS 1991; 88:6486 Vincek, Genomics 1989; 5:773 refiNadeau, Genomics 1991; 9:78 ref:Neufeld, Mamm Genome 1991; 1:242 J Mol Evol 1991; 33:495

ref:Amor, PNAS 1985; 82:4453 Vincek, Genomics 1989; 5:773 Immunogenetics 1988; 27:133 PNAS 1986; 83:5111 ref:Walsh, Immunogenetics 1991; 33:290 PNAS 1985; 82:44.53 PNAS 1986; 63.":3601 J Biol Chem 1986; 258:4106 Endocrinology 1988; 123:1923 Immunogenetics 1990; 32:200 Immunogenetics 1990; 32:200 PNAS 1987; 84:3325 Nucl Acid Res 1991; 19:2563 Genetics 1990; 126:1103 Genetics 1990; 126:1103 Genetics 1990; 126:1103 Genomics 1992; 12":106 Nature 1990, 343:617 Nature 1990, 343:617 Development 1991; 111:561 Development 1991; 111:561 ref:Nadeau, Genomics 1991; 9:78 ref:Nadeau, Genomics 1991; 9:78 ref:Nadeau, Oenornics 1991; 9:78 ref:Nadeau, Genomics 1991; 9:78 ref:Nadeau, Genornics 1991; 9:78 ref:Fox, Cell 1985; 40:63 Genetics 1991; 129:237 Cell 1984; 36:783 Vincek, Genomics 1989; 5:773 ref.'Nadeau, Genetics 1989; 122:895 ref:Nadeau, Genomics 1991; 9:78 ref:Nadeau, Genomics 1991; 9:78 ref:Nadeau, Genetics 1989; 122:895 Genetics 1991; 129:237 Genes & Devel 1987; 1:376 P N A S 1989; 86~22 M a m m Genome 1991; 1:37 ref:Nadeau, Genomics 1991; 9:78 C o n t i n u e d on next p a g e

J.T. E p p i g : C l o n e s a n d P r o b e s

396 Table 3. Continued. Oar Symbola

17

D17Leh66

Lor

Name

DNA segment, Chr 17, Lehrach-66 (t)

Probeb

RFLVc Ccniaetd

+

Tu66

+ + + 17

D17Leh66D DNA segment, Chr 17, Lehrach-66D

" (=T66) p66M-RT

17

D17Leh66E

DNA segment, Chr 17, Lehrach-66E

p66M-RT

17 17

D17Leh80 D17Leh89

DNA segment, Chr 17, Lehrach-80 (t) DNA segment, Chr 17, Lehrach-89 (t)

Tu80 Tu89

17

D17Leh94

DNA segment, Chr 17, Lehrach-94

Tu94

17

D17Leh96

DNA segment, Chr 17, Lehrach-96

Tu98

17

D 17Lehl08

DNA segment, Chr 17, Lehrach-108 (t)

Tul08

+ + + + + + + + + + + + + + + + + +

17 17 17

D17Lehlll D17Leh116 D17Lehll9

DNAsegment, C h r l 7 , L e h r a c h - l l l DNAsegment, C h r l 7 , L e h r a c h - l l 6 DNA segment, Chr 17, L e h r a c h - l l 9 (t)

Tulll Tull6 Tull9

"

17

D 1 7 L e h l l 9 I DNA segment, Chr 17, Lehrach-119I

(=Tl19)

D 1 7 L e h l l 9 I I DNA segment, Chr 17, L e h r a c h - l l 9 I

D17Leh122

DNA segment, Chr 17, Lehrach 122(t)

+ + + +

C4.74, C4.38, CA.47, C4.1, C4.37, C2.119, C4.41, C4.43 pll9AR

17

+ + + + + + + + + + +

probelll C6.90,C6.95 C4.74, C4.38, C4.47, C4.1, C4.37, C2.119, C4.41, C4.43 pll9AR

17

+ +

Tu122

+ + + + + + + +

17 17 17

D17Leh145 DNA segment, Chr 17, Lehrach 145 D17Leh154 DNA segment, Chr 17, Lehracho154 D17Lehl71 DNA segment, Chr 17, Lehrach 171

Tu145 Tu154 Tul71

17 17

D17Leh173 Dl7LehlS0

D N A segment, Chr 17, Lehrach 173 D N A segment, Chr 17, Lehrach 180

Tu173 TulS0

17 17

D17Leh236 D17Leh443

DNA segment, Chr 17, Lehrach 236 DNA segment, Chr 17, Lehrach 443

Tu236 Tu443

17

D17Leh467

DNA segment, Chr 17, Lehrach 467

Tu467

+ + + + + + + + + + + +

co:Fox Rohme 5-Schimenti co:H Lehrach co:L S i l v e r co:H Lehrach co:Hermann Schimenti King co:B H e r m a n n co:Hermann Eicher co:Hermann King co:B H e r m a n n co:J Lehrach co:J Lehrach Bucan co:Sucan Pilder co:H Lehrach co:M Bucan co:H Lehrach Bucan Degen Weis co:H Lehrach co:Fox Rohme Gasser co:H Lehrach co:H Lehrach co:H Lehrach co:H Lehrach co:H Lehrach Lehrach Pilder MacMurray co:H Lehrach co:H Lehrach Herrmann Herrmann Herrmann Herrmann Herrmann co:H Lehrach co:B H e r r m a n n co:B H e r r m a n n co:B H e r r m a n n Herrmann Herrmann Herrmann co:H Lehrach co:B H e r m a n n Eicher co:B H e r r m a n n co:Fox Pilder Rohme co:H Lehrach co:H Lehrach Rohme co:H Lehrach co:H Lehrach co:H Lehrach co:H Lehrach Rohme Bucan co:M Bucan Rohme co:H L e h r a c h Bucan co:M Buean Rohme co:M Bucan co:M Bucan

Referencee

Cell 1985; 40.~3 Cell 1984; 36:783 J Mol Biol 1987; 194:583 refiFigueroa, Genetics 1988; 119:157 ref:Gallahan, J Virol 1987; 61:218 ref:Nadeau, Genetics 1989; 122:895 Cell 1986; 44:469 J Mol Biol 1987; 194:583 M a m m Genome 1991; 1:37 ref:Nadeau, Genetics 1989; 122:895 Cell 1986; 44:469 Genetics 1990; 125:431 Vincek, Genomics 1989; 5:773 M a m m Genome 1991; 1:37 ref:Nadesu, Genetics 1989; 122:895 unpublished Cell 1984; 35:783 Genes & Devel 1987; 1:376 Vincek, Genornics 1989; 5:773 Genetics 1991; 129:237 ref:Nadeau, Genomics 1991; 9:78 ref:Neufeld, M a m m Genome 1991; 1:242 ref:Rohme, Cell 1984; 36:783 Genes & Devel 1987; 1:376 Genomics 1990; 8:49 Mol Cell Biol 1986; 6:441 Vincek, Genomics 1989; 5:773 Cell 1985; 40:63 Cell 1984; 36:783 Biochem Genet 1988; 26:475 ref:Vincek, Genomics 1989; 5:773 ref:Figueroa, Geneitcs 1988; 119:157 ref:Neufeld, M a m m Genome 1991; 1:242 ref:Nadeau, Genomics 1991; 9:78 ref:Nadeau, Genomics 1991; 9:78 ref:Hermann, Cell 1986; 44:489 Genetics 1991; 129:237 Genetics 1988; 120:545 ref:Nadeau, Genetics 1989; 122:895 Vincek, Genomics 1989; 5:773 Cell 1986; 44:469 Cell 1987; 46:813 Cell 1987; 48:813 Cell 1987; 48:813 Cell 1987; 46:813 ref:Figueroa, Geneitcs 1988; 119:157 Cell 1986; 44:469 ref:Eicher, Genetics 1990; 125:431 ref:Washburn, Genet Res 1990; 56:185 Cell 1987; 46:813 Cell 1987; 48:813 Cell 1987; 48:813 ref:Figamroa, Geneites 1988; 119:157 Cell 1986; 44:469 Genetics 1990; 125:431 refiWashburn, Genet Res 1990; 56:185 Cell 1985; 40:63 Genetics 1991; 129:237 Cell 1984; 36:783 ref:Figueroa, Genetics 1988; 119:157 ref:Nadeau, Genomics 1991; 9:78 Cell 1984; 36:783 ref:Nadeau, Genomics 1991; 9:78 Vincek, Genornics 1989; 5:773 ref:Neufeld, M a m m Genome 1991; h242 ref:Nadeau, Genomics 1991; 9:78 Cell 1984; 36:783 Genes & Devel 1987; 1:376 Vincek, Genomics 1989; 5:773 Cell 1984; 36:783 ref:Rohme, Cell 1984; 36:783 Genes & Devel 1987; 1:376 Vineek, Genomics 1989; 5:773 Cell 1984; 36:783 Vincek, Genomics 1989; 5:773 ref:Neufeld, M a m m Genome 1991; 1:242 C o n t i n u e d on next p a g e

397

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Syrnt~a

Locus Name

probeb

17 17

D17LehS08 D17Leh525

17 17 17

D17Leh550 DNA segment, Chr 17, Lehraeh 550 D17Rpll DNA segment, Chr 17, Rcswell P a r k - l l D17Rp17 DNA segment, Chr 17, Roswell Park-17

17

D17Slkl

DNA segment, Chr 17, Lehrach 508 DbIA segment, Chr 17, Lehrach 525

DNA segment, Chr 17, Sloan Kettering-1 (also referred to as B144)

RFLVc C,ontac~t

TuS08 Tu525

Tu550 pMKll09 pMK174

17

DI7Tul

DNA segment, Chr 17, Tubingen-1

B144 clone cosmid 3.1 cos 3.4.1, 3-4-1E1-3

17

D17Tu2

DNA segment, Chr 17, Tubingen-2

clone 9.4.3 derivative

17 17 17

D17Tu3 D17Tu4 D17Tu5

DNA segment, Chr 17, Tubingen-3 DNA segment, Chr 17, Tubingen-4 DNA segment, Chr 17, Tubingen-5

cos5-50 tosS-l-1 ecsS-50A, probe Marc

17 17 17 17 17 17 17 17 17 17 17 17 17 17

D17Tu6 D17Tu7 D17Tu8 D17Tu9 DI7Tu10 D17Tull D17Tul2 D17Tul3 D17Tul4 D17Tul5 D17TuI6 D17Tul7 D17Tul8 D17Tu19

(withdrawn, see D(Yru6) (withdrawn, see DOTu7) (withdrawn, see DOTuS) DNA segment, Chr 17, Tubingen-9 DNA segment, Chr 17, Tubingen-10 (withdrawn, see DOTul 1) (withdrawn, see DOTul2) (withdrawn, see DOTul3) DNA segment, Chr 17, Tubingen-14 (withdrawn, see DOTul5) DNA segment, Chr 17, Tubingen-16 (withdrawn, see DOTu17) DNA segment, Chr 17, Tubingen-18 DNA segment, Chr 17, Tubingen-19

17 17 17 17

D17Tu20 D17Tu21 D17Tu22 DI7Tu23

DNA DNA DNA DNA

17

D17Tu24

DNA segment, Chr 17, Tubingen-24

17

D17qka25

DNA segment, Chr 17, Tubingen-25

17

D17Tu26

DNA segment, Chr 17, Tubingen-26

17

D17Tu27

DNA segment, Chr 17, Tubingen-27

17 17 17 17 17

D17Tu28 D17Tu29 D17Tu30 D17Tu31 D17Tu32

DNA segment, Chr 17, Tubingen-28 DNA segment, Chr 17, Tuhingen-29 DNA segment, Chr 17, Tubingen-30 (withdrawn, see DOTu31) DNA segment, Chr 17, Tubingen-32

17 17

D17Tu33 D17Tu34

DNA segment, Chr 17, Tubingen-33 DNA segment, Chr 17, Tubingen-34

17 17

D17Tu35 D17Tu36

DNA segment, Chr 17, Tubingen-35 DNA segment, Chr 17, Tubingen-36

17

D17Tu37

DNA segment, Chr 17, Tubingen-37

17 17 17 17 17

D17qka38 DI7Tu39 D17Tu40 Dt7Tu41 D17Tu42

DNA DNA DNA DNA DNA

17

D 17Tu43

DNA segment, Chr 17, Tubingen-43

17 17

D17Tu44 D 17Tu45

(withdrawn, see DOTu44) DNA segment, Chr 17, Tubingen-45

segment, segment, segment, segment,

segment, segment, segment, segment, segment,

Chr Chr Chr Chr

Chr Chr Chr Chr Chr

17, 17, 17, 17,

Tubingen-20 Tubingen-21 Tubingen-22 Tubingen-23

17, Tubingen-38 17, Tubingen-39 17, Tubingen-40 17, Tubingen-41 17, Tubingen-42

co:H Lehrach co:M Bucan co:M Bucan co:M Bucan co:H Lehrach co:Elliott,Mann c o: Ma nn co:RW Elliott co:RW Elliott Sarventnick King

Refemlesa

unpublished Genes & Devel 1987; 1:376 Vincek, Genomics 1989; 5:773 ref:Neufeld, Mamm Genome 1991; 1:242 ref:Nadeau, Genomics 1991; 9:78 Mouse News Letter 1985; 71:48 Genetics 1986; 114:993 Eicher, Genetics 1990; 125:431 ref:Washburn, Genet Res 1990; 56:185 Genetics 1986; 113:723 PNAS 1989; 86.'222

King

Mamm Genome 1991; 1:37

co:WD Roeder

ref:Wroblewski, Immunogenetics 1990; 32:200

Tsuge

Immunogenetics 1987; 26:378 Immunogenetics 1990; 32:200 PNAS 1987; 84:3325 Genetics 1987; 117:101 Genomics 1989; 5:773 Genetics 1987; 117:101 Genomics 1989; 5:773 Genomics 1989; 5:773 Genomics 1989; 5:773

Wroblewski 4- K a s a h a r a + Figueroa + Vincek + Figueroa + Vincek + Vincek + Vincek + Mizuno + Vincek

Immunogenetics 1989; 30:105 Genomics 1989; 5:773

cos6-3-2 cosl-6-2

+

Vincek Vincek

Genomics 1989; 5:773

cos4-1

+

Vincek

Genomics 1989; 5:773

cosl-l-1

+

Vincek

Genomics 1989; 5:773

L62 ~.73

+ + + +

Vincek Vincek co:J Klein Vincek Vincek + Vincek Vincek + co:J Klein + Vincek + eo:J Klein Vincek + coal Klein + Vincek + co:J Klein Vincek + co:J Klein Vincek Vincek + Vineek

Genomics 1989; 5:773 Genomics 1989; 5:773 reflNeufeld, Mamm Genome 1991; 1:242 Genomics 1989; 5:773 Genomics 1989; 5:773 Genomics 1989; 5:773 Genomics 1989; 5:773 ref:Sertic, Mamm Genome 1992; 2:138 Gonomics 1989; 5:773 ref:Neufeld, Mamm Genome 1991; 1:242 Genomics 1989; 5:773 refiSertic, Mamm Genome 1992; 2:138 Genomics 1989; 5:773 ref:Neufeld, Mamm Genome 1991; 1:242 Genomics 1989; 5:773 ref:Sertic, Mamm Genome 1992; 2:138 Genomics 1989; 5:773 Genomics 1989; 5:773 Genomics 1989; 5:773

+ + + + +

Genomics 1989; 5:773 ref:Neufeld, Mamm Genome 1991; 1:242 Genomics 1989; 5:773 Genomics 1989; 5:773 ref:Moen, Mamm Genome 1991; 1:217 Genomics 1989; 5:773 Genomics 1989; 5:773 ref:Sertic, Mamm Genome 1992; 2:138 Genornics 1989; 5:773 ref:Sertic, Mamm Genome 1992; 2:138 Genomics 1989; 5:773 Genomics 1989; 5:773 Genomics 1989; 5:773 Genomics 1989; 5:773 Genomics 1989; 5:773 ref:Neufeld, Mamm Genome 1991; 1:242 Genomics 1989; 5:773 ref:Sertic, Mamm Genome 1992; 2:138

L56 :k~47 ~.182 ~.134 D17Tu23 probe k113 L94 D17Tu25 probe ~.160 L171 DITI'u27 probe L130 ~.13 ~150 k108 k154 :k355 Tu34 ~.139 Z253 D17Tu36 probe cos2-8 D17qk~7 probe Z307 ~ ~99 ces4-66 ~.137 k335 D17Tu43 probe k280

Vincek co:J Klein Vineek Vincek co:J Klein Vincek Vincek + co:J Klein Vincek + co:J Klein Vincek + Vincek + Vincek Vincek + Vincek + co:J Klein Vincek + co:J Klein Vincek

Genomics 1989; 5:773

Genomics 1989; 5:773 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

398 Table 3. Continued. Chr Syrakl a

LocusName

17 17 17 17

D17Tu46 D17Tu47 D17Tu48 D17Tu49

(withdrawn, see DOTu46) DNA segment, Chr 17, Tubingen-47 DNA segment, Chr 17, Tubingen-48 DNA segment, Chr 17, Tubingen-49

17

D17TuS0

DNA segment, Chr 17, Tubingen-50

17 17 17 17 17

D17TuS1 D17Tu52 D1TWas70 D21S56h Gnat-2

(withdrawn, see DOTu51) DNA segment, Chr 17, Tubingen-52 DNA segement, Chr 17, Univ of Wash-70 DNA segment, Chr 17, human D21S56 guanine nucleotide binding protein, a transducing-2

17 17 17

17 17

17 17 17 17

17

Probeb

RFLVc O m l ~ l

k98 ~273 X200 Tu49

+ +

"

+

k370 Tu50

+ +

~214 probe 70038 [H] 520-10R [H] GNAT2 cDNA [13] Gnat-2 cDNA

+

Vincek Vincek Vincek co'~l Klein co:J Klein Vincek co:J Klein

Vincek Disteche + Cheng Sparkes Lochrie co:M Lochrie + co:M Lochrie Grr probe + co:J Klein growth and reproductive region grr JR] grc probe + co:J Klein clone 27.1 + Steinmetz major histocompatibility, pseudo class I H-2ps pH-2IIa, pH-2II + Steinmetz major histocompatibility, class I H-2 pH-2IIa + co:L Hood pH-2III co:L Hood pH2d37C + co:Lalanne C1432 + Flaherty pmbeb7 Schulze + Eicher 407Barn Weiss major histocompatibility, class I (5') pH-21 + Steinmetz major histocompatibility-2, D region H-2D pH-2d-3 Bregegere 07.1 + Shin AWl.2X-B, AW1.2.3B + co:L Flaherty AWl.2.7B + co:L Flaherty H-2D b pH203 Reyes major histocompatibility-2, Db unnamed Watts Lda3A, LdM, II2.20, Rubocki probe 7 (from II2.20) + co:Steinmetz D2M, D3M, D4M, a3, Rubocki 33.3A, Ld3'Flc, 50.2A Rubocki cesmid 35.1, cesmid 37.1 Wroblewski H-2D d c49.2 Taylor major histocompatibility-2, Dd Livant pH-2 d- 1 Bregegere Kvist 16.1, probe 10 + co:Steinmetz H-2D f clone B2 Horton major histocompatibility-2, Df pH-2III + Steinmetz H.2D k major histocompatibility-2, Dk unnamed Watts kl.3, probe 9 + co:Steinmetz unknown Schepart major histocompatibility-2, DP H-2DP unknown Linsk major histocompatibility-2, Dq H-2Dq co6mids 5.1, 3.1, 34.2, 95 Rubocki Rubocki D2, D3 genes cosmid 6 Rubocki D4 genes cesmids 17, 33.3 co:LR Pease H-2D/LVl major histocompatibility-2, D/LVl (H-2D v) 13.1, 15.1, 9.1, 44.1 co:LR Pease H-2D/LV2 major histocompatibility-2, D/LV2 (H-2D v) 19.1, 4.1, 9.1, 45.1, 46.1 H-2D/LV3 major histocompatibility-2, D/LV3 (H-2D v) 16.1, 18.1, 24.1, 25.1, 15.1 co:LR Pease Muller immune response region of H-2 cosmid II3.31 H-2I Steinmetz (includes H-2Aa, H-2Ab, H-2Ea, H-2E,b cesmids: IIl.1, II2.1 Steinmetz H-2Eb2, H-2Ob, H-2Pb) cesmids: II2.19, II6.19 Steinmetz cosmid II9.19 Steinmetz probel4(or 1) H-2Aa,Ab Ia region of H-2 Steinmetz cesmids: II10.6, II5.9 + co:McConnell I-Agen + co:D Singer I-Aspoc + Seidman pla~-I + Steinmetz probes 6, 7, 12.2 + Uematsu 8,10,13 Steinmetz Uematsu probe A, probe C + Uematsu + Uematsu Shiroishi (from B10.MOL-SGR) cosmid SGR.31 Shiroishi (from C57BI.J10J) cesmid B10.30 Shiroishi (from B10.A) cosmid B10A.1

Referencee

Genomics 1989; 5:773 Genomics 1989; 5:773 Genomics 1989; 5:773 ref:Henson, PNAS 1991; 88:6486 ref:Neufeld, Mamm Genome 1991; 1:242 Genomics 1989; 5:773 ref:Henson, PNAS 1991; 88:6486 Genomics 1989; 5:773 Cytometry 1990; 11:119 PNAS 1988; 85:6032 Cytogenet Cell Genet 1985; 48:696 Science 1985; 228:96 ref:Blatt, PNAS 1988; 85:7642 ref:Vincek, Genomics 1989; 5:773 ref:Neufeld, Mamm Genome 1991; 1:242 ref:Vincek, Immunogenetics 1990; 32:293 Cell 1981; 25.'683 Cell 1981; 24:125 ref:Kotzin, J Exp Med 1987; 165:1237 ref:Lader, Immunogenetics 1985; 22:49 Cell 1985; 41:489 PNAS 1985; 82:1503 Mol Cell Biol 1983; 3:750 Genetics 1990; 125:431 Nature 1984; [email protected] Cell 1981; 24:125 Nature 1981; 2 9 2 : 7 8 Nature 1983; 306:380 ref:Walsh, Immunogenetics 1991; 33:290 ref:Walsh, Immunogenetics 1991; 33:290 Immunogenetics 1982; 16:1 J Immtmol 1987; 139:3878 J Exp Med 1990; 171:2043 ref:Fujishima, Diabetologia1989; 32:118 J Exp Med 1990; 171:2043 J Exp Med 1990; 171:2043 Immunogenetics 1990; 32:200 PNAS 1985; 82:1175 Cell 1986; 47:481 Nature 1981; 292:78 PNAS 1981; 78:2772 ref:Fujishima, Diabetologia1989; 32:118 J Immunol 1990; 145:1782 Cell 1981; 24:125 J Immunol 1987; 139:3878 ref:Fujishima, Diabetologia1969; 32:118 J Immunol 1986; 136:3489 J Exp Med 1986; 164:794 J Exp Med 1990; 171:2043 J Exp Med 1990; 171:2043 J Exp Med 1990; 171:2043 ref:Cai, J Exp Med 1992; 175:583 ref:Cai, J Exp Med 1992; 175:583 ref:Cai, J Exp Med 1992; 175:583 EMBO J 1987; 6:369 EMBO J 1984; 3:2995 EMBO J 1984; 3:2995 EMBO J 1984; 3:2995 Cell 1986; 44:895 Cell 1986; 44:895 J Immtmol 1986; 136:3076 ref:Gallahan, J Virol 1987; 61:218 refiEpstein, J Exp Med 1985; 161:1219 Cell 1986; 44:895 Immunogenetics 1988; 27:96 Cell 1986; 44:895 Immunogenetics 1988; 27:96 EMBO J 1986; 5:2123 Immunogenetics 1988; 27:96 Immunogenetics 1990; 31:79 Immunogenetics 1990; 31:79 Immunogeneties 1990; 31:79 C o n t i n u e d on n e x t p a g e

399

J.T. Eppig: Clones and Probes Table 3.

Continued.

Cbr Symh:~a

17

17

17 17 17 17

17

17

H-2Aa

~

Name

histocompatibility-2, class II antigen Act

Probeb

pAAC6 eosmid 24.2 " , probe 2 ActD# 105

RFLVc C~lta~ l

Benoist co:Steinmetz + eo:Steinmetz Rogers + co:DS Singer I-Actprobe + co:L Glimeher (k allele) cos H-2 k 8.1 frag co:L Glimcher pCAA6 co:D Mathis (p allele) A7.1A, A8.1A eo:GA Bishop (from NZW) Aa z genomic (PCR) Ogawa (from NON) NON H-2Aa eDNA Acha-Orbea H-2Ab histocompatibility-2, class II antigen A~ t~894 + eo:Wu + Nadeau unnamed (B6.C-H-2 bml2) MeIntyre cos 34.2 Malissen pIA~-i Robinson cosmid 41.1 eo:Steinmetz " , probe 1 + co:Steinmetz (b allele) cos I]3101 Larhammar flag eosI[3101-exon III, IV + L u n d (k allele) pCAA8 co:H McDevitt (p allele) A7.1A, A8.1A co:GA Bishop pABP.10, pABP.16 co:GA Bishop pABP.10.2, pABP.34 co:GA Bishop (z allele from NZW) WABG-5 Ogawa (w30-1 allele, Tuw7) I-A~w30-1 genomic Golubic (w 31-2 allele, Tuwl0) LA]3w31-2 genomic Golubic (w36-1 allele, Tuw8) I-A]]w36-1 genomic Golubic (from ILI strain) PCR-H-2Ab exon2-1Ll Koide (from CTS strain) PCR-H-2Ab exon2-CTS Koide (from NOD strain) PCR-H-2Ab exon2-NOD Koide (from NON strain) PCR-H-2Ab exon2-NON Koide H-2Ab-3 histocompatibility-2, class II antigen A~-3 cosLS11 Widera H-2Ab2-b3 recombination hotspot, IA~2 -IA~3 cosrrdds SGR.31, B10.30, Shiroishi cosmid B 10A. 1 Shiroishi AHTll, HT22 P C R primer Shiroishi H-2Ea/H-2Eb H-2, class II antigen Ea, E~ probe16(or10) Steinmetz probelS(or10) Steinmetz cosmids: II4.14, II12.6 Steinmetz H-2Ea histocompatibility-2, class II antigen Ect clone 32.1 co:Hood Art~t co:Steinmetz , probe 4, 5, 6 + co:Steinmetz probe 7 eo:L Hood + co:L Hood + co:L Hood kA, JP34 Mathis (from NZW) A~ z genomic (PCR) Ogawa Ead cos Id-ct-1 Hyldig-Nielsen frag cosId-ct-l-exon III, IV+ Lund H-2Eb histocompatibility-2, class II antigen E~ B1,Ba Steinmetz + Lafuse I-E~ probe + co:L Glimcher probe 4 eo:L Hood Lafuse cosmid 24.2 co:Steinmetz " , probe 3 + co:Steinmetz pE~ + co:Steinmetz pEB10 Mengle-Gaw pEBbl, pEB10, pEBu25 Mengle- Gaw pE~24-1 Saito pEBB24 Denaro cEBs2.g, EBsl Mengle-Gaw PCR-397bp ~31-~2intron + co:B Saha (AGGC) repeat plus flank PCR-3' BamHI + co:B Saha (from NOD) NOD H-2Eb eDNA Acha-Orbea (from NON) N O N H-2Eb e D N A Aeha-Orbea El3d (from NZB) BEB-45, BEB-43 Ogawa E~ z (from NZW) WEBD-3 Ogawa E~ w31"l allele (Tuw8) I-E]3w31"l genomic Golubic E~W31 allele (Tuwl0) I-E~ w31 genomic Golubic H-2Eb-2 histocompatibility-2, class II antigen E~-2 probe 1, 2, 3, 4, 5 + Braunstein

P,efe~mcee

PNAS 1983; 80:534 rcfiFujishima, Diabetelogia 1989; 32:118 refiFujishima, Diabetologia1989; 32:118 J Immunol 1985; 134:630 ref:Siracusa, Genetics 1991; 127:169 ref:Bailey, Eur J Immunol 1991; 21:959 ref:Martin, J Immunogenetics 1989; 17:151 ref:Benoist, PNAS 1983; 80:534 ref:Harton, Immunogenetics 1991; 34:358 Immunogenetics 1980; 32:63 Immunogenetics 1991; 34:57 refiRobinson, J Immunol 1983; 131:2025 Genomics 1991; 9:78 Nature 1984; 308:551 Science 1983; 221:263 J Immtmol 1983; 131:2025 ref:Fujishima, Diabetelogia 1989; 32:118 ref:Fujishima, Diabetologia1989; 32:118 Cell 1983; 34:179 J Autoimmunity 1990; 3:289 refiEstess, PNAS 1986; 83:3594 ref:Harton, Immunogenetics 1991; 34:358 refiHarton, Immunogenetics 1991; 34:358 ref:Harton, Immunogenetics 1991; 34:358 Immunogenetics 1990; 32:63 Genet Res 1987; 5(k.137 Genet IRes 1987; 5~.137 Genet Res 1987; 5(k.137 International Immunol 1989; 2:189 International Immunol 1989; 2:189 International Immunol 1989; 2:189 International Immunol 1989; 2:189 PNAS 1985; 82"~500 Immunogenetics 1990; 31:79 Immunogenetics 1990; 31:79 EMBOJ 1991; 10:681 Cell 1986; 44:895 Cell 1986; 44:895 Cell 1986; 44:895 ref:Steinmetz, Nature 1982; 300:35 Devel Genet 1987; 8:1 ref:Fujishima, Diabetologia 1989; 32:118 ref:Fujishima, Diabetologia1989; 32:118 ref:McNicholas, Science 1982; 218:1229 ref:Lafuse, Immunogenetics 1986; 24:352 ref:Lafuse, J Immunogenetics 1990; 17:169 Cell 1983; 32:745 Immunogenetics 1990; 32:63 Nucl Acid Res 1983; 11:5055 J Autoimmunity 1990; 3:289 Nature 1982; 30~.35 Immunogenetics 1986; 24:352 ref:Bailey, Eur J Immunol 1991; 21:959 ref:Steinmetz, Nature 1982; 300:35 Immunogenetics 1986; 24:352 ref:Fujishima, Diabetologia 1989; 32:118 ref:Fujishima, Diabetologia1989; 32:118 ref:Romano, Immunogenetics 1989; 29:142 PNAS 1983; 80:7621 PNAS 1983; 80:7621 PNAS 1983; 80:5520 EMBO J 1984; 3:2029 PNAS 1985; 82:2910 refiPadgett, J Immunol 1991; 147:2764 refiPadgett, J Immunol 1991; 147:2764 Immunogenetics 1991; 34:57 Immunogenetics 1991; 34:57 Immunogenetics 1990; 32:63 Immunogenetics 1990; 32:63 Genet Res 1987; 5(k.137 Genet Res 1987; 5(k.137 EMBO J 1986; 5:2469 C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

400 Table 3. Continued. Chr Symbda

17

17

17 17 17

17 17

17

17

17 17 17

17 17 17 17 17

~Name

Pt~ b

Winoto Mains probe 2(or D) Steinmetz Steinmetz probe 4(or C) Steinmetz probe 5(or B) cosmids: I16.13,I16.3 Steinmetz 13/1, 20/2, 14/2, probe A, B Abe probes 1 through 16 Abe cosmids: 9-2-3, 7-1-1 Uehara major histocompatibility K (t 12) Uehara 9-2~ 1-3-1, 2-7-3, 9-3-10, 3-2-1, 4-3-1 Uehara cosmids: 10-6-5, 3-6-3, 12, Uehara major histocompatibility K (t w5) 8-5-3, 10-1-2, 9-2-5, 3-1-2 Uehara co:H-S Shin cosmid 16, cosmid 24 Schulze H-2K b pH2KO1 major histccompatibility-2, Kb pH202 Reyes Schulze C1.4.1 co: SG Nathenson Weiss HSPST8 BmlR3/1 + Uehara ~ b e 81) Kress (unique sequence) + Uehara L,S1/1, Bin1-18 + Weiss flank, H-2Kb LS1/1,Bml-18,Bml-R3/1 + Uehara H-2Kb flank probe 1,2,3 + co:Weiss 5'KI + co:A Mellor Schulze H-2K bml major histocompatibility-2,K bml El07.1.1 co: SG Nathenson H-2Kbin29 cDNA H-2K bin29 major histocompatibility-2,K bm29 co:LR Pease p1954 + Forejt H-2K d major histocompatibility-2,K d Kvist 2.14 Lalanne pH-2d-24 Lalanne pH-2d-33 Horton clone A2 H-2K f major histocompatibility-2,K f Arnold 6D,7A H-2K k major histocompatibility-2,K k Arnold c27.2 (from AKR) Sim Watts cos64, cosl02, cos6, (from C3H) Watts cos55, cos61 (from C3H) Minamide H2Kf8 or C3Hf-8 (from C3H/HeN) Sim Kress H-2Kq major histocompatibility-2, Kq pH8, pill3 Kress unnamed Morita P5 Watts H-2K1 k major histocompatibility-2, K1 k (pseudogene) unnamed Sim (from C3H/HeN) C3Hf-19 Sim (from K36.16, AKR thymoma) 407-7 Abe H-2K2 major histocompatibility-2, K2 (pseudogene) probe A Abe "H-2Kel" H-2K region expressed gene E1 13/1, probes 3, 4, 6 Abe "H-2Ke2" H-2K region expressed gene E2 20/2, probe 6 KE2 cDNA, KE2 genomic co:K Artzt co:H-S Shin cosmid 24, cosmid 19 probes Abe "H-2Ke3" H-2K region expressed gene E3 co:H-S Shin cosmid 19, probe 8 14/2, pmbos 11, 12 Abe "H-2Ke4" H-2K region expressed gene E4 co:H-S Shin cosmid 32, clone 10.2 Abe probe 14 "H-2Ke5" H-2K region expressed gene E5 Rubocki major histocomatibility-2, L region II.2.20-cross H-2L co:Seidman pMHC-1 H-2L d major histocomatibility-2, L d Margulies pLd-4, probe L co:T Shiroishi co:Margulies pL Rubecki probes: 1, 2, 3, 3A, Sun probos: 4, 5, 6, 7 Moore 27.5 Linsk unknown Linsk unknown major histocompatibility-2, Lq H-2Lq Rubocki cosmida 33.3, 36,53,38 co:M Steinmetz cos 4.24 "H-2M?" histocompatibility-2, M region locus ? Cho 4.24A (from cos 4.24) H-2K

major histocompatibility-2, K region

rapS.17.1

RFLVc Omtac~

Refewmcee

PNAS 1983; 80:3425 Immunogenetics 1986; 23:357 Cell 1986; 44:895 Cell 1986; 44:895 Cell 1986; 44:895 Cell 1986; 44:895 EMBO J 1988; 7:3441 EMBO J 1988; 7:3441 EMBO J 1987; 6:83 EMBO J 1987; 6:83 EMBOJ 1987; 6:83 EMBO J 1987; 6:83 EMBO J 1987; 6:83 ref:St-Jacques, Mol Cell Biol 1990; 10:138 Immunogenetics 1981; 14:383 PNAS 1982; 79:3270 Mol Cell Biol 1983; 3:756 ref:Ozawa, Nucl Acid IRes 1990; 18:4185 EMBOJ 1983; 2:453 EMBO J 1987; 6:83 J Biol Chem 1983; 258:13929 EMBO J 1987; 6:83 Nature 1984; 310:650 EMBO J 1987; 6:83 ref:Mellor, PNAS 1985; 82:5920 ref:Lund, J Autoimmunity 1990; 3:289 PNAS 1983; 80:2007 ref:Ozawa, Nucl Acid IRes 1990; 18:4185 ref:Horton, J Immunol 1991; 147:3180 Genet Ros 1988; 51:111 EMBO J 1983; 2:245 PNAS 1983; 80:7561 Nucl Acid Res 1983; 11:1567 J Immunol 1990; 145:1782 Nucl Acid Ros 1984; 12:9473 Nucl Acid Res 1984; 12:9473 J Immunogenetics 1990; 17:133 Immunogenetics 1989; 29:355 Immunogenetics 1989; 29:355 Immunogenetics 1988; 27:148 J Immunogenetics 1990; 17:133 Nature 1983; 306:602 J Biol Chem 1983; 258:13929 Immunogenetics 1985; 21:367 Irnmunogenetics 1989; 29:355 J Immunogenetics 1990; 17:133 J Immunogenetios 1990; 17:133 EMBO J 1988; 7:3441 EMBO J 1988; 7:3441 EMBO J 1988; 7:3441 ref:Ha, Gene 1991; 107:345 ref:St-Jacquos, Mol Cell Biol 1990; 10:138 EMBO J 1988; 7:3441 ref:MacMurray, Mamm Genome 1992; 2:87 EMBO J 1988; 7:3441 ref:St-Jacquea, Mol Cell Biol 1990; 10:138 EMBO J 1988; 7:3441 J Exp Med 1990; 171:2043 ref:Evans, PNAS 1982; 79:1994 Nature 1982; 295:168 ref:Fujishima, Diabetologia1989; 32:118 ref:Rornano, Immunogenetics 1989; 29:142 PNAS 1986; 83:9606 J Exp Med 1985; 162:1588 Science 1981; 215:679 J Exp Med 1986; 164.'794 J Exp Meal 1986; 164:794 J Exp Med 1990; 171:2043 ref:Cho, PNAS 1991; 98:5197 PNAS 1991; 88:5197

Continued on next page

J.T. Eppig: Clones and Probes

401

Table 3. Continued. Chr ~ a

17

H-2M1

Locus Name

Probeb

histoeompatibility-2, M region locus 1

17

H-2M2

histoeompatibility-2, M region locus 2

17

H-2M3

histocompatibility-2, M region locus 3

17

H-2Q2, H-2Q3

17

H-2Q1, H-2Q2, H-2Q3

H-2, Q regionlocus 2,-3 H-2, Q regionlocus 1,-2,-3

RFLVc CcnU~ta

Mbl cos 5.22 5.22D (from cos 5.22) cos 5.22 5.22C (from cos 5.22) cos 14RB-A, pCD22, clone H6R1, probe P7, probe pH2d4, pCD12, probe A2-7 p46.11

+ +

+

B1.24, H26 c50.2.1

17 17 17 17 17 17 17 17 17

H-2Q1 k histoeompatibility-2, Q region locus 1k H-2Q2 k histocompatibility-2, Q region locus 2 k H-2Q4 histocompatihility-2, Q region locus 4 H-2Q4b histocompatibility-2, Q region locus 4b H-2Q4 d histocompatibility-2, Q region locus 4 d H-2Q4 k histocompatibility-2, Q region locus 4 k H-2Q4P histocompatibility-2, Q region locus 4P H-2Q4k, H-2Q5 k H-2, Q regionlocus 4, -5 H-2Q4, H-2Q6, H-2Q8 H-2, Q region locus 4, -6, -8

+ Q1 k clone Q2 k clone MMMHCQ4A (microsat)+ Q4b clone cosmid 65.1 Q4k clone pMJP-2 cosmid 9.3 c1432 +

17 17 17 17

H-2Q5 b histocompatibility-2, Q region locus 5 b H-2Q5 d histoeompatibility-2, Q region locus 5 d H-2Q5 k histocompatihility-2, Q region locus 5 k H-2Q4, H-2Q5 H-2, Q regionlocus 4, -5

cosmid B2.5 cosmid 65.1 Q5 k clone Bml-2, B2.5

17

H-2Q6b

+

17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17 17

histocompatibility-2, Q region locus 6b

cosmid 2.17 H-2Kb flank probe 1,2,3 H-2Q6 d histocompatibility-2, Q region locus 6 d eosmid 46.2 H-2Q6, H-2Q8 H-2, Q regionlocus -6,-8 c1462, c1465, c1466 H-2Q7b histocompatibility-2, Q region locus 7b Q7b clone H-2Q7 d histocompatibility-2, Q region locus 7d Q7 d clone H-2Kb flank probe 1,2,3 H-2Q8 histocompatibility-2, Q region locus 8 27.1 H-2Q8 b histoeompatibility-2, Q region locus 8b Q8 b clone H-2Kb flank probe 1,2,3 H-2Q7, H-2Q9 H-2, Q region locus 7,-9 (intron) c5.23 H-2Q8 d, H-2Q9 d H-2, Q region locus 8d,-9 d cosmid 46.1 H-2Q9 b histocompatibility-2, Q region locus 9b cosmid B4.8 H-2Kb flank probe 1,2,3 H-2Q10 histoeompatibility-2, Q region locus 10 10Q10 p r ~ e H-2Q10b histoeompatibility-2, Q region locus l0 b Q10b clone H-2Q10 k histocompatibility-2, Q region locus 10k cosmid 9.2 H-2Q10 k histocompatibility-2, Q region lc~us 10k Qlo k clone H-2T1 d histocompatibility-2, T region, locus 1 (pseudo) pTLA.8 k24.8 H-2T3 d histocompatibility-2, T region, locus 3 pTLA.8, pTLA.4 H-2T9 b histocompatihility-2, T region, locus 9 c15 H-2T10 b histocompatibility-2, T region, locus 10 c15 H-2Tll b histocompatibility-2, T region, locus 11 c15, c3 H-2T12 b histocompatibility-2, T region, locus 12 c15, e3 H-2T13 b histocompatibility-2, T region, locus 13 c3, c116, c153 H-2T14 b histocompatibility-2, T region, locus 14 c116, c153 H-2T15 b histocompatibility-2, T region, locus 15 c116, c153 H-2T16 d histocompatibility-2, T region, locus 16 pTLA.8 H-2T18 d histocompatibility-2, T region, locus 18 pTLA.8, pTLA.4 (formerly BALB/c T13 gene) pTLA.5, pTLA. 1 H-2TI9 d histocompatibility-2, T region, locus 19 c37-16 H-2T20 d

histoeompatibility-2, T region, locus 20

c37-16

+ +

+

+ +

+

Singer co:DS Singer co:M Steinmetz Cho eo:M Steinmetz Cho Wang Wang Wang Wang Winoto Lyon Weiss Robinson Winoto O'Neill Watts Watts Montagutelli Robinson Steinmetz Watts Palmer Weiss Flaherty O'Neill Weiss Steinmetz Watts Weiss Robinson Weiss co:Weiss Steinmetz co:Flaherty Devlin Watts co: Weiss Steinmetz Devlin co: Weiss O'Neill Steinmet~ Weiss co: Weiss Cosman Mellor Weiss Watts Fisher Fisher Fisher Brown Brown Brown Brown Brown Brown Brown Fisher Fisher co:DA Fisher Transy Sun Transy Sun

l~fe~moee

Immunogenetics 1988; 28:13 Vincek, Genomios 1989; 5:773 ref:Cho, PNAS 1991; 88:5197 PNAS 1991; 88:5197 ref:Cho, PNAS 1991; 88:5197 PNAS 1991; 88"~197 Cell 1991; 66:335 Cell 1991; 66:335 Cell 1991; 66:335 Cell 1991; 66:335 PNAS 1983; 80:3425 Immtmogenetios 1988; 27:375 Nature 1985; [email protected] Immunogenetios 1988; 27:79 PNAS 1983; 80:3425 Immunogenefios 1986; 24:368 EMBO J 1989; 8:1749 EMBO J 1989; 8:1749 M a m m Genome 1991; 1:255 Immtmogenetics 1988; 27:79 Cell 1982; 28:489 EMBO J 1989; 8:1749 J Exp Med 1987; 198:95 J Immtmogenet 1989; 18:283 PNAS 1985; 82:1503 Immunogenetios 1986; 24:368 Nature 1985; [email protected] Cell 1982; 28:489 EMBO J 1989; 8:1749 Nature 1985; [email protected] Immunogenetics 1988; 27:79 Nature 1985; 310:650 refiMellor, PNAS 1985; 82:5920 Ceil 1982; 28:489 refiElliott, Immunogenetic8 1989; 29:371 EMBO J 1985; 4:3203 EMBO J 1989; 8:1749 refiMellor, PNAS 1985; 82:5920 Cell 1981; 25:683 EMBO J 1985; 4:3203 ref:Mellor, PNAS 1985; 82:5920 Immunogenetics 1986; 24:368 Cell 1982; 28:489 Nature 1985; 310:650 ref:Mellor, PNAS 1985; 82:5920 PNAS 1982; 79:4947 Cell 1984; 36:139 J Immunogenet 1989; 16:283 EMBO J 1989; 8:1749 J Exp Med 1985:162:528 J Mol Evol 1989, 28:306 J Exp Med 1985:162:528 Immunogenetios 1988; 27:239 Immunogenetics 1988; 27:239 Immunogenetics 1988; 27:239 Immunogenetics 1988; 27:239 Immtmogenetics 1988; 27:239 Immunogenetics 1988; 27:239 Immunogenetics 1988; 27:239 J Exp Med 1985:162:528 J Exp Med 1985:162:528 ref:Dolby, Immunogenetics 1990; 32:380 J Exp Med 1987; 166:341 J Exp Med 1985; 162:1588 J Exp Med 1987; 166:341 J Exp Med 1985; 162:1588 Continued on next p a g e

J.T. Eppig: Clones and Probes

402 Table 3. Continued. Symbola

~

Name

Probeb

RFLVc C~tactd

17

H-2T21 d

bistocompatibility-2,T region, locus 21

c37-16

17

H-2T22 d

histecompatibility-2,T region, locus 22

c37-16, ~..16

17

H-2T23

histecompatibility-2,T region,locus 23

~.16, p37EE89 pH-2d-37

17

H-2T23 d

histocompatibility-2,T region, locus 23

c37-16

17 17

H-2Tlev Haml

H-2T region endogenous virus (in T14) histecompatihi]ity antigen modifier-1

Ham2

histecompatibility antigen modifier-2

Hba-ps4

hemoglobulin a-4, pseudogene

5'TL.1, pTLevl + 5.9B, B1, B3, B5 cos 5.9 5.9B (from cos 5.9) Ham2 eDNA cos 5.9 5.9E(from cos 5.9) Ham2 eDNA full-length phage clone l(apsi4 = a-r + + + +

17

+

Y44 17

Hkr-1

GLI-Kruppel family member HKR1

[H] pHKR1 RS-RsaI-680

17

Hmgi

high mobility group protein I

HGMI eDNA

17

Hprt-psl

Hprt, pseudogene- 1

~.HPT30

17

Hsp70

heat shock protein 70kDa

+ + + + + +

17

Hsp84-1

heat shock protein 84kDa-1

17

Igf2r

insulin-like growth factor II receptor

17

lnt-3

mammary tumor integration site-3

17

"Mns-17"

minor satellite Chr 17 (centremeric)

17 17 17 17 17 17

Ms15-3 minisatenite 15-3 ~Ms2-2-5-P2" minisatellite 2-2-5-P2 (human D1S57) ~Ms6-3-8-Pl" minisatellite 6-3-8-P1 (human D14SI) "Ms8-2-9-P2" minisatenite 8-2-9-P2 (human INS) "MsS-3-6-P2" minisatellite 8-3-6-P2 (human INS) Mut methy|malonyl coenzyme A mntase

pHPGK-7e pM 1.8 pMg.5 unnamed [H] pH2.3 Hsp70 probe pXS3.0 pmHS214 Hsp70 PCR (TA)n rpt MMHSP68C (microsat) 1~4 clone A, clone B

+ + + +

+ +

+ + + + +

eDNA-3.7, eDNA3.13, [R] prI2R-20 [H] Igf2r PCR-Igf2r pal, pCz-4, pCz-5 pAl, clone241 pal probe A pMR150

[H] probes 33.15 pYNZ2 pAW101 pINS310 pINS31O [H] MCM26

+ +

+ + + + +

moMCM2O9 17

Odc-rsl5

ornithine decarboxylase related seq-15

I~R6 (pDOC934 derived) +

Transy Sun Transy Sun Transy Lalanne Transy Transy Sun Pampeno Monaco eo:M Steinmetz Cho Monaco co:M Steinmetz Cho ce:JJ Monaco co:P Leder co:P Leder D'Etmtachio co:R Popp co:R Popp Mann co:LM Silver co:LM Silver Nadeau co:P Leder Pilder Ruppert co:B Vogelstein Johnson Johnson Isamat co:Melton 1-Elliott,Mann co:Morimoto Hunt Giebel Hunt Gaskins co:L Flaherty Aujame Auj a me Freund Montagutelli Romano Moore co:S Moore Hoffmann MacDonald co:U Francke Morgan Telford Gallahan co:R Callahan co:R Callahan Gallahan Voliva co:VM Chapman co:ND Hastie Jeffreys Julier Julier co:G Bell co:G Bell Ledley Sertic Wilkemeyer Threadgill Rheaume co:FG Berger

Referencee

J FA-pMed 1987; 166:341 J Exp Med 1985; 162:1588 J Exp Med 1987; 166:341 J Exp Med 1985; 162:1588 J Exp Meal 1987; 166:341 Ceil 1985; 41:469 J Exp Med 1987; 166:341 J Exp Med 1987; 166:341 J Exp Med 1985; 162:1588 Immunogenetics 1988; 28:247 Science 1990; 250:1723 ref:Cbo, PNAS 1991; 88:5197 PNAS 1991; 88:5197 Science 1990; 250:1723 ref:Cho, PNAS 1991; 88:5197 PNAS 1991; 88:5197 ref.'Attaya, Nature 1992; 355:647 Nature 1981; 293:196 tel:Fox, Immunogenetics 1984; 19:125 J Exp Med 1984;159:958 Eicher, Genetics 1990; 125:431 ref:Washburn, Genet Res 1990; 56:185 Genetics 1986; 114:993 Vincek, Genomics 1989; 5:773 ref:Neufeld, Mamm Genome 1991; 1:242 Genomics 1991; 9:78 re~Henson, PNAS 1991; 88:6486 Genetics 1991; 129:237 Mol Cell Biol 1988; 8:3104 ref:Saunder, Genomics 1990; 8:525 J Biol Chem 1988; 263:18338 Genomics 1992; 12:503 Somatic Cell Mol Genet 1988; 14:359 Vincek, Genomics 1989; 5:773 Mouse News Letter 1985; 71:48 ref:Krawczyk, Mol Bio Rpt 1987; 12:27 ref:Zakeri, Mol Cell Biol 1988; 8:2925 Devel Biol 1988; 125:200 PNAS 1985; 82:6455 Immunogenetics 1990; 32:286 ref:Walsh, Immunogenetics 1991; 33:290 Can J Genet Cytol 1986;28:1064 Mol Cell Bio 1985; 5:1780 J Exp Med 1992; 175:683 Mamm Genome 1991; 1:255 Immunogenetics 1989; 29:142 Gene 1987; 56:29 Vincek, Genomics 1989; 5:773 Gene 1988; 74.'491 Science 1988; 239:1134 ref:Laureys, Genomics 1988; 3:224 Nature 1987; 32~.301 Mol Repred Devel 1990:27:81 J Viral 1987; 61:66 ref:Robbins, J Virel 1992; 66:2594 ref:Siractma, Genomics 1991; 10:313 J Virol 1987; 61:218 Nucl Acid Res 1983; 11:8847 ref:Breccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1983; 11:6965 Nucl Acid Res 1987; 15:2823 PNAS 1990; 87:4585 PNAS 1990; 87:4585 tel:Juliet, PNAS 1990; 87:4585 ref:Julier, PNAS 1990; 87:4585 PNAS 1988; 85:3518 Genomics 1990; 6:560 Biochem J 1990; 271:449 Cytogenet Cell Genet 1990, 53:112 Mol Endocrinol 1989; 3:1243 ref:Siractma, Genetics 1991; 127:169 C o n t i n u e d on next p a g e

403

J.T. Eppig: Clones and Probes Table 3.

Continued.

Chr Symbola

17

Locus Name

lh~eb

RFLVc C o a t ~d

Otfi3

octamer-binding transcription factor-3

17 17 17

Pcna-ps2 Pgk-lps2 Pgk-2

Oct-3 eDNA 3' Otf-3 eDNA 5' Otf-3 cDNA 2G22, 2G3, 2G19 proliferating cell nuclear antigen, pseudo-2 Pcna-pa2 genomic phcsphoglycerate kinase-1 pseudogene 2 ? pheaphoglycerate kinase-2 Probe G (=pMPGK-2)

17

Pim-1

proviral integration, MCF, site-1

17 17 17 17 17

17 17

17

fragment B

+

B12 unnamed plasmid A C5C clone (probe A) " (probe A) " (probe A) PIM- 1A

PrA (C5C subclone) pMB20, pMB69, pMB102 MP17,MP6,MC9,MC 16, MPLS, MP13, MPL2 MP33B Pmv-57 polytropic murine leukemia virus-57 JS-5 "RD(H-2)" unknown gene located between C4 & Bf WL623, WL10S rds retinal degeneration-slow B7, R24, IG3, IG3.B9A B:I, R:I BgA-II B9A Rnul4 U14 small nuclear RNA (encoded in hsc70) JLM2772 Slp sex-limited protein pSlp/1 pG2.9, pDSll9, SX~ XB BX (from FM strain) pFSlp/5.2 probe 8 (from pFSlp/5.2) kSlp-3.22,kSlp-3.5, kSlp-3.14,kSlp-2.1, kSlp-2.8,MSlp- 1.14, kSl~2.5,MSlp-3.20 (from DBA/1 strain) pDC4/3 pSlp12J ccemids: 15.3, 38.3 ccsmids: 11.1, 13.4 (w7d gene) cosmids: el-16, cl-25, cosmids: cl-35, cl-42 cosmids: c1-18, cl-27 cosmids: el-17, cl-34 M8A (w7c gene) cosmids: el-l, cl-36 (wTo gene) cosmids: cl-29, el-18 M1A, M8B (w7a gene) cosmids: ci-30, ci-15 cosmids: ci-22, cl-6, cesmid: d-23 ~.17B Sod-2 superoxide dismutase-2, mitochondrial pHMnSODI Pim-2 Plg

+ +

+ + + + + + + + +

proviral integration, MCF, site-2 plasminogen

+ +

+

+ +

+ +

pHMnSod4 +

17

T

17 Tcp-1

brachyury

pine75

(promoter region) (T and flank) t-complex protein-1

p190R10RS p66MRT p30, kB1.25.1, kB1.16.1

(a allele)

pT1b11, pT1623, ~.TIB3 ).TIB4, %TIB6, ~.TIB7

+ +

Scholer co:K Artzt Rosner Siracusa Siracusa Okazawa co:A Matsukage Adra Boer Goto Adra Adra Nagarajan co:HT Cuypers Cuypers co:A Berns Hilkens co:A Berns co:A Berns co:A Berns co:A Berns co:A Berns eo:Hendriks Pilder Vijaya Breuer Degen Degen Degen Frankel Levi-Strauss Travis Travis Travis Travis Liu Nonaka Stavenhagen Stavenhagen Nonaka co:M Takahashi Nonaka Nonaka Nonaka Nonaka Nonaka Sepich Stavenhagen Stavenhagen Nakayama Nakayama Nakayama Nakayama Ogata Nakayama Nakayama Ogata Nakayama Nakayama Nakayama Ogata Hallewell Figueroa co:G Bell Figueroa Pilder Herrmann Wilkinson co:BG H e r r m a n n co:BG H e r r m a n n co:Willison co:K Willison co:A Matsushiro co:A Matsushiro

Refe~mcee

F.MBO J 1990; 9:2185 ref:Yeom, Mech Devel 1991; 35:171 Nature 1990;, 345.'686 Genomics 1991; 10:313 Genomics 1991; 10:313 EMBO J 1991; 10:.2997 ref:Yamaguchi, Nucl Acid Res 1991; 9:2403 Somatic Cell Mol Genet 1988; 14:69 Mol Cell Biol 1987; 7:3107 Exp Cell Res 1990; 186:273 Somatic Cell Mol Genet 1988; 14:69 Somatic Cell Mol Genet 1988; 14:69 PNAS 1986; 83:2556 ref:Warren, Nucl Acid Rcs 1987; 15:3195 Cell 1984; 37:141 ref:Ark, Genomics 1991; 10:385 Somatic Cell Mol Genet 1986; 12:81 ref:Nadeau, Genetics 1987; 117:533 ref.'Siracusa, Genetics 1991; 127:169 ref:Nadeau, Genomics 1991; 9:78 ref:Neufeld, M a m m Genome 1991; 1:242 ref:Henson, PNAS 1991; 88:6486 Vincek, Genomics 1989; 5:773 Genetics 1991; 129:237 J Viroi 1987; 61:1164 EMBO J 1989; 8:743 Genomics 1990; 8:49 Genomics 1990; 8:49 Genomics 1990; 8:49 M a m m Genome 1992; 2:110 Science 1988; 240:201 Nature 1989; 338:70 Nature 1989; 338:70 Nature 1989; 338:70 Neuron 1991; 6:61 Nucl Acid R ~ 1990; 18:6565 PNAS 1984; 81:6822 Cell 1988; 55:247 Cell 1988; 55".247 Immunol Rev 1985; 87:81 ref:Fujishima, Diabetologia1989; 32:118 Immunol Rev 1985; 87:81 Immunol Rev 1985; 87:81 Immunol Rev 1985; 87:81 Immunoi Rev 1985; 87:81 Immunol Rev 1985; 87:81 PNAS 1985; 82:5895 Mol Cell Biol 1987; 7:1716 Mol Cell Biol 1987; 7:1716 J Immunoi 1987; 138:620 J Immunol 1987; 138:620 J Immunol 1987; 138:620 J Immunol 1987; 138:620 J Immunol 1991; 147:2756 J Immunol 1987; 138:620 J Immunol 1987; 138:620 J Immunol 1991; 147:2756 J Immuaol 1987; 138:620 J Immunol 1987; 138:620 J Immunol 1987; 138:620

J Immunol 1991; 147:2756 Nucl Acid Rcs 1986; 14:9539 Immunogenetics 1988; 28:260 Howard, Genetics 1990; 126:1103 Immunogenetics 1988; 28:260 Genetics 1991; 129:237 Nature 1990;, 343:617 Natuer 1990;, 343:657 ref:Rashbass, Nature 1991; 353:348 ref:Rashbass, Nature 1991; 353:348 Cell 1986; 44:727 Vincek, Genomics 1989; 5:773 ref:Kubota, Gene 1991; 195:269 ref:Kubeta, Gene 1991; 105:269 C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

404 Table 3. Continued. Chr S ~

17

a

Tcp-1

L(~us Name

t-complex protein-l(b allele)

Probeb

RFLVc C(mlactd

pB1.4

+ + + + + +

17 17

Tcpl-rsl Tcp-10

t-complex protein-1 related sequence-1 t-complex protein 10

(from t6/twl mice) (from tlubl/tw5 mice)

Tcp-10a

17

Tcp-10b

t-complex protein 1Oa

(from 129) (from 129-t wS) t-complex protein 10b

(from 129) t allele

17

Tcp-1Oc

t-complex protein 10c

~.B1.3.2, ~.B1.4.2 29x pTla3, pTlaS, pTla9, pTla11, pTlbm, ~.TIA2, ~.T1A4, ~.TIA8 Tcp-lx cDNA Bb-53, Cg3-38,Bb-40 Bb-40, Ca-45 Ca-52,Ca-45 66.5.1 eosmid CW1, CW2, CW3, CW6, CW7, CW9, CWl0, CWll, CW12 cosmid 181, cosmid 195 pTcrl2 Tcrl6R]H.2, Cg3-79 Cb2-8, Tcrl6R]H.2 2-31BG cosmids CD-1O, CD-20 cesmid 2-31 Tcp-1Oa cDNA Tcp-1Oa t eDNA (PCR) cesmid 193 pTcrl2 Tcr16R/H.2, Cg3-79 Cg3-79 Cg3-79, B1>59 2-31BG, Cb2-8 C-aB/CLo, W-BG co6rnids 2-31, i, 2, 2-7 comids CWX7, W, u coemids CW6 Tcp-10b eDNA pTcr16, pTcrl0

cesmid 196 Tcr16R/H.2, Cg3-79 C-aB/CLo, Cb2-8 pTcr7, pTcr9, pTcr12 pTcr12 Cg3-100

+

+ + +

+ + + +

+ +

+

+ + +

+ +

17

Tcte-1

(from 129) (129-t w5) t-complex associated testis expressed-1

Cg3-79, Cg3-100 Tcp-10c cDNA Tcp-10c t cDNA pNS2 Sill-3' flank

17

Tcte-3

17

Tctex-1

t-complex associated testis expressed-3 (=D17Lehll7c) t-complex testis expressed-1

17

Tctex-2

t-complex testis expressed-2

17 17 17 17 17 17

Tctex-3 Tctex-4 Tctex-5 Tctex-6 Tctex-7 Thbs-2

t-complex testis expressed-3 t-complex testis expressed-4 t-complex testis expressed-5 t~complex testis expressed-6 t-complex t ~ t i s expressed-7 thrembospondin-2

+ + +

pmtcte-1 Tcte-3 cDNA c5-1 + clone 16, Tctex-1 cosmid plasmid 3-1 + Tctex-1 cDNA clone 33 Tetex-2 cDNA + Tctex-3 genomic Tctex-4 cDNA Tctex-5 eDNA Tctex-6 cDNA Tctex-7 cDNA pMTSP2-A, pMTSP2-B Thbs-2 genomic mTSP2 cDNA +

Willison co:K Willison co:K Willison co:K Willison Lyon Nadeau Dudley co:K Willison Willison co:Willison co:A Matsushiro co:A Matsushiro co:A Matsushiro Dudley ce:J Sehimenti co:L Silver co:J Schimenti Willison Bunard Bullard Bullard Davies co:LM Silver Bullard Rosen Rosen Rosen Rosen Pilder Pilder Davies co:LM Silver Bullard Schimenti Rosen Rosen Rosen Rosen Rosen Rosen Pilder Schimenti co:Schimenti Pilder Davies Bullard Rosen Schimenti co:LM Silver Schimenti Bibbins Pilder Sehimenti Pilder Pilder Sarvetnick Bibbins ATTC co:Silver co:J-Y Tsai Rappold co:H Lehrach Lader Lader Howard co:K Artzt Lader co:K Artzt co:K Artzt co:K Artzt co:K Artzt co:K Artzt co:K Artzt Bornstein Bornstein co:VM Dixit

Ref~

JEEM 1986; 97:151 Eicher, Genetics 1990; 125:431 tel:Washburn, Genet Res 1990; 56:185 ref:Henson, PNAS 1991; 88:6486 Immunogenetics 1988; 27:375 Genomics 1991; 9:78 Genet Res 1991; 57:147 ref:Moen, Mamm Genome 1991; 1:217 Cell 1986; 44:727 ref:Pilder, Genetics 1991; 129:237 ref:Kubota, Gene 1991; 105:269 ref:Kubota, Gene 1991; 105:269 ref:Knbota, Gene 1991; 105:269 Genet Res 1991; 57:147 J Mol Biol 1987; 194:583 ref:Nadeau, Genetics 1989; 122:895 J Mol Biol 1987; 194:583 Genet Res 1990; 56:193 Genetics 1990; 124:957 Genetics 1990; 124:957 Genetics 1990; 124:957 Mamm Genome 1991; 1:235 ref:Mancoll, Mamm Genome 1992; 2:201 Genetics 1990; 124:957 Genornics 1990; 8:134 Genomics 1990; 8:134 Genomies 1990; 8:134 Genomies 1990; 8:134 Genomies 1991; 12:35 Genomics 1991; 12:35 Mamm Genome 1991; 1:235 ref:Mancoll, Mamm Genome 1992; 2:201 Genetics 1990; 124:957 J Mol Biol 1987; 194:583 Genomics 1990; 8:134 Genomics 1990; 8:134 Genomics 1990; 8:134 Genomics 1990; 8:134 Genomics 1990; 8:134 Genomics 1990; 8:134 Genomics 1991; 12:35 Cell 1988; 55:71 ref:Bullard, Mamm Genome 1991; 1:228 Genomics 1991; 12:35 Mamm Genome 1991; 1:235 Genetics 1990; 124:957 Genomics 1990; 8:134 Cell 1988; 55:71 ref:Mancoll, Mamm Genome 1992; 2:201 J Mol Biol 1987; 194:583 Genomies 1989; 5:139 Genetics 1991; 129:237 J Mol Biol 1987; 194:583 Genomics 1991; 12:35 Genomies 1991; 12:35 PhD thesis 1985, SUNY, Stony Brook Genomics 1989; 5:139 ref:Sarvetnick, Immunogenetics 1989; 30:34 Vincek, Genomics 1989; 5:773 ref:Mancoll, Mamm Genome 1992; 2:201 EMBO J 1987; 6:1975 ref:WiUison, Genet Res 1990; 56:193 Cell 1989; 58:969 Cell 1989; 58:969 Genetics 1990; 126:1103 ref:Ha, Devel Genet 1991; 12:318 Cell 1989; 58.069 ref:Ha, Devel Genet 1991; 12:318 ref:Ha, Devel Genet 1991; 12:318 ref:Ha, Devel Genet 1991; 12:318 rel2Ha, Devel Genet 1991; 12:318 tel:Ha, Devel Genet 1991; 12:318 tel:Ha, Devel Genet 1991; 12:318 J Biol Chem 1991; 266:12821 PNAS 1991; 98:8636 ref:Laherty, J Biol Chem 1992; 267:3274 C o n t i n u e d on n e x t p a g e

405

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Symbola

LocusName

17

Thse-

t-haplotype specific elements

17

Thy-2

thymus cell antigen-2

17 17 17 17 17

Tla Tla b Tla c Tla-rs Tnfa

thymus leukemia antigen thymus leukemia antigen, b allele thymus leukemia antigen, c allele Tla related sequence tumor necrosis factor, a

Probeb

RFLVc C o a t ~ l

TSE8, TSE26, TSE9, TSE23, TSE18, cos6-1-1, cos6-3-4, cosl0-5-3, cos6-9-1, cos9-3-4, cos6-3-2 %Thy19.4, Thy 19.4-5' Thy19.4-3' p37E3 c25.1 17.3A pK36-HindIII p-mTNF

+ + + + + +

+ MuTNF-a + pAT153-trp-MRNF85 p-mTNF pSVd2-3mTNF

[H] TNF probe

17

Tnfa}Tnfb

tumor necrosis factor a,

17

Tnfb

tumor necrosis factor,

17

Tpx- 1

testis specific gene-1

17

Tpx-2

testis specific gene-2

17 17 18

Xmv-36 Xmv-57 Adrb-2

xenotrepic murine leukemia virus-36 xenotropic murine leukemia virus-57 adrenergic receptor, 9-2

]8

Camk4

calmodulin kinase IV

Tnfa exon 4 flag Tnfa PCR (AC)n rpt Tnfa CA repeat PCR MMTNFAB (microsat) (microsat) done603-38 done603-1 clone603-18 cosmid 3.1, cosmid 4.1, cos mid JW.1 pmTa2 Tnf genomic unnamed pMuLT p701 [H] TNF probe MMTNFAB (microsat) 1-1-1H4, B2-1 1-1-1H4, cosl-l-1, B4(1)4, C5-2 cosl-l-1, 1-1-1H4 1-1-1H4 [H] 49HT8 JS-6flS-10 JS~N~S- 10 [Ha] Adrb-2 cDNA Adrb-2 genomic CaM kinase IV cDNA

+ + + + + + + + +

+ + +

+ + + + + +

18

Cdl4

CD14 antigen

18 18

Cdx-1 Csfmr

caudal type homeo box-1 colony stimulating factor 1 receptor (includes Fim-2)

k8 Yll MS7-4 MS7-4, MSTX, MS7-6 BH8 clone 341, 341-PB04 clone 17(1), 341-HS18 17(1)-SP04 341-ppl [V] pSM7C IV] pSM7C, [H] CSF1R pSP65-v-fms 7.755 341-PB04

]8 18

D18Lehl D18Leh2

18

Egr-1

DNA segment, Chr 18, Lehrach-1 DNA segment, Chr 18, Lehrach-2 early growth response-1 (=Zfp-6)

+

+ +

+ + +

pGR105-LT, p755 B2 SINE (PCR spretus) + B1 SINE (GATA)3 + DF2, DF6 OC3.1 rngEgr-l.1, p2.4, p6.6 Kr24codl, Kr24cod2, Kr24cod3, Kr24cod4, Kr24cod5

Uehara Uehara Uehara Uehara Uehara Broreon Brorson Kourilsky Obata Fisher Sire Fransen co:Tavernier, Fiers Pennica co:HM Shepard co:B Allet, Biogen co:B Allet, Biogen co:Biogen co:ATCC Freund Freund Jongeneel co:JA Todd co:JA Todd Gardner Gardner Gardner Wroblewski Wroblewski co:Jongeneel Shirai Gray Li Firestein co:WD Roeder co:ATCC

Montagutelli Kasahara Kasahara Kasahara Kasahara Kasahara Seboun Kasahara Frankel Frankel co:RJ Lefkowitz co:JM Allen Sikela Sikela Sikela co:J Sikela Matsuura Setoguchi Duprey Sola Sola Sola co:B Sola co:JN Ihle co:C Sherr Wang Collart Rothwell co:S Gisselbrecht co:S Gisselbrecht co:S Gisselbrecht Eccles Cox Cox Lemaire Sukhatme Tsai-Morris Lemaire Lemaire Lemaire

Genetics 1990; 126:1093 GenetiQs 1990; 126:1093 Genetics 1990; 126:1093 Genetics 1990; 126:1093 G e n e t ~ 1990; 126:1093 Immtmogenetics 1989; 30:273 Immtmogenetics 1989; 30:273 Cell 1985; 41:469 PNAS 1985; 82:5475 J Exp Meal 1965; 162:528 J Immtmogeneties 1989; 16:335 Nucl Acid Res 1985; 13:4417 ref:Ltmd, J Autoimmunity 1990; 3:289 PNAS 1985; 82.~60 ref:Siracusa, Genomics 1991; 10:313 ref:Collart, J Immunol 1987; 139:949 ref:Collart, J Immunol 1987; 139:949 ref:Qin, Mol Irnmunol 1989; 16:1021 ref:Walsh, Immunogenetics 1991; 33:290 J Exp Med 1992; 175:683 J Exp Med 1992; 175:683 J Exp Med 1990; 171:2141 ref:Hearne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 J Immunol 1987; 139:476 J Immtmol 1987; 139:476 J Immtmol 1987; 139:476 Immunogenetics 1990; 32:200 Immtmogenetics 1990; 32:200 ref:Nedospasov, Nucl Acid Res 1986;14:7713 DNA 1988; 7:193 Nucl Acid Res 1987; 15:3937 J Irnmunol 1987; 138:4496 Anal Biochem 1987; 167:381 ref:Wroblewski, Immunogenetics 1990; 32:200 ref:Walsh, Immunogenetics 1991; 33:290 Marnm Genome 1991; 1:255 Immunogenetics 1989; 29:61 Genomi~ 1989; 5:527 Genonfics 1989; 5:527 PNAS 1987; 84:3325 Transpl Prec 1987; 19:815 Cold Spr Hbr Syrnposium 1986; 51:237 Irnmtmogenetics 1991; 34:132 J Virol 1989; 63:1763 Mamm Genome 1992; 2:110 ref:Sundaresan, Sore Cell Mol Gen 1989;15:367 tel:Byrd, Genomics 1991; 11:794 PNAS 1987; 54:3038 Genomics 1990; 8:579 Genomies 1990; 8:579 ref:Jones, FEBS Lett 1991; 289:205 Nucl Acid Res 1989; 17:2132 BBA 1989; 1008:213 Genes & Devel 1988; 2:1647 J Virol 1986; 60:718 J Virol 1986; 60:718 J Virol 1986; 60:718 ref.'Buchberg, Genetics 1989; 122:153 ref:Siraetma, Genetics 1991; 127:169 ref:Hoggan, J Virol 1988; 62:1055 Genomies 1988; 3:172 J Immunol 1987; 139:949 Oncogene R ~ 1987; 1:311 re~ Sola, J Virel 1988; 62:3973 tel:Knight, Mol Cell Probes 1990; 4:497 ref:Sakai, Biochem Genet 1901; 29:103 Gene 1991; 108:285 Genomics 1991; 10:375 Genomics 1991; 10:375 PNAS 1988; 85:4691 Cell 1988; 53:37 Nuel Acid Res 1988; 16:8835 Mol Cell Biol 1990; 10:3456 Mol Cell Biol 1990; 10:3456 Mol Cell Bioi 1990; 10:3456 C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

406 Table 3. Continued. Chr Symbola

~

Name

18

Emv-21

endogenous ecotropic MuLV-21

18

Fech

ferrochelatase

18

Fgfa

fibroblast growth factor, acidic

18

Grl-1

glucocorticoid receptor-1

18

Ii

Ia associated invariant chain

18

Mbp

myelin basic protein

Mbp proximal promoter

18 18

Mbp Mbp

myelin basic protein (deleted) myelin basic protein (shiverer mutant)

18

Mbp

myelin basic protein (mld mutant)

18

"Mns-18"

minor satellite Chr 18 (centromeric)

18

Mtv-2

mammary tumor virus locus-2

18 18

Mtv-38 Pdea

mammary tumor virus locus-38 cGMP-phosphodiesterase a

Probeb

RFLVc (h~ta~d

pEco Chattopadhyay pEc-B4 Chan pEco, pEt-B4 + Taylor plasmids 6A, 19, 16D Brenner kMF10, ;LMF5, XaMF12 Taketani [B] aFGF cDNA, Jacquemin [B] aFGF(BamHI/SphI) cDNA Jacquemin [H] pJC3-5 Abraham + co'J Abraham pW28, clone21, pSV2Wrec co:G Ringold pSV2Wrec + co:M Davidson pN10 Northrop SC 115 cDNA Nohno pSV2 Wrec co:GM Ringold + co:GM Ringold + co:GM Ringold pIi5, pIi-1 Singer pIi5 + co:Richards Koch + co:HC Morse + co:K Huppi pIi-1 + Yamamoto ccsl0.7 Yamamoto Koch MMIIGC (microsat) + co'~IATodd PP535 Roth clones: M44, M72, M78 Newman k471, B7, Molineaux pdF191,~L2 Molineaux pNZ111, pdF191 deFerra pHF43 + co:RA Lazzarini [R] pMBP-1 Roach + co:M Krall MPB + co:S Gisselbrecht pMBP-2 Kimura Ccs138 Readhead co:C Readhead 4.5BamHI probe (Cos138)+ Ainger pSP-GM1 Takahashi + Eicher pexl Takahashi + co:HC Morse III Mbp probe + Sikela cosBJABS, ccsHJAB12 co:K Mikoshiba coaBJAB15, cosHJAB31 co:K Mikoshiba BP53/62, BP36/12 Tamura MMBPS2 (microsat) + co'JA Todd (micmsat) + co:JA Todd k25 + Molineaux Ccsm 352, Cosm 214, Popke C ~ m 211, Cosm 191, Popko Ccsm 231, Cosm 201, Popke Costa 31, Ccsm 41c, Popko Cosm 14, Cosm 91, Popko Ccsm 101, Costa 111, Popko C~m 132, Ccsm 302, Popko Ccsm 12c Popko kHOB1011,~.HOB1021,~.HOB2031 Okano " co:K Mikoshiba cosHOm21, cosHOm8-2, co:K Mikoshiba co6HOml2, co~HOmlS-2 co:K Mikeshiba Co~ml2, Ccsm291, Popko Co6m352, km332 Popko pMRIS0 Voliva co:VM Chapman co:ND Hastie MMTV (GR-40) Michalides Hynes MTV- LTR Michalides MTV env probe + Koizumi MMTV cDNA or DNA + co:J Ball, J Majors MMTVS-21 + co:JE Majors []3]p13-E + Danciger Pdea probe + Sikela MPA- 15, MPA-11, Baehr MPA-4, MPA-8 Baehr

Ref~

PNAS 1980; 77"~774 PNAS 1980; 77:5579 Genomics 1989; 5:221 P N A S 1991; 88:849 J Biol Chem 1990; 265:19377 Neurcsci Left 1990; 116:23 Neur~ci Lett 1990; 116:23 EMBO J 1986; 5:2523 ref:Cox, Genomics 1991; 10:375 Danielson, EMBO J 1986; 5:2513 ref:Cox, Genomics 1991; 10:375 J Biol Chem 1986; 251:11064 Nucl Acid Res 1989; 17:445 ref:Shyamala, Endocrinology 1990; 126:2882 ref:Byrd, Genomics 1991; 11:794 ref:Sakai, Biochem Genet 1991; 29:103 EMBO J 1984; 3:873 Immunogenetics 1985; 22:193 EMBO J 1987; 6:1677 ref:Cox, Genomics 1991; 10:375 ref:Byrd, Genomics 1991; 11:794 Immunogenetics 1985; 21:83 J Immunol 1985; 134:3461 EMBO J 1987; 6:1677 ref:Hearne, Mamm Genome 1991; 1:273 J Neumsci Res 1986; 16:227 PNAS 1987; 84:886 PNAS 1986; 83:7542 PNAS 1986; 83:7542 Cell 1985; 43:721 ref:Sakai, Biochem Genet 1991; 29:103 Cell 1983; 34:799 ref:Byrd, Genomics 1991; 11:794 ref:Sola, J Viral 1988; 62:3973 J Neurochem 1985; 44:692 Cell 1987; 48:703 refiBoyle, Genomics 1992; 12:106 Genetics 1992; 130:367 Cell 1985; 42:139 Genetics 1990; 125:431 Cell 1985; 42:139 ref:Siracusa, Genetics 1991; 127:169 Genomics 1990; 8:579 ref:Okano, J Neurochem 1991; 56:560 ref:Okano, J Neurochem 1991; 56:560 EMBO J 1990; 9:3101 ref:Hearne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 PNAS 1986; 83:7542 Cell 1987; 48:713 Cell 1937; 48:713 Cell 1987; 48:713 Cell 1987; 48:713 Cell 1987; 48:713 Cell 1987; 48:713 Cell 1987; 48:713 Cell 1987; 48:713 EMBOJ 1988; 7:77 co:Okano, J Neurochem 1991; 56:560 ref:Okano, J Neurochem 1991; 56:560 ref:Okano, J Neurochem 1991; 56:560 Neuron 1988; 1:221 Neuron 1988; 1:221 Nucl Acid Res 1983; 11:8847 ref:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid IRes 1983; 11:6965 Virology 1985; 142:278 PNAS 1982; 78:2038 Virology 1985; 142:278 BBRC 1990;, 166:336 ref:MacInnea, Virology 1984; 132:12 refiSiracusa, Genetics 1991; 127:169 Exp Eye Res 1990, 51:185 Genomics 1990; 8:579 FEBS Lett 1991; 278:107 FEBS Left 1991; 278:107 Continued on next p a g e

407

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Symt~a

18

Pdgfrb

LocusName

platolet-derived growth factor receptor ~

Probeb

RFLVc C o n t ~ 1

pGR102

Yarden co:Yarden co:LT Williams 5'Pdgfr, 3'Pdgfr Eccles Pmv-20 polytropic murine leukemia virus-20 JS-5 Frankel JS-5, MCF100 + Frankel Ptpt protein tyrosine phosphatase, T-cell [H] PTPT cDNA co:D Cool MPRP cDNA Mosinger, J r "Tgl71" transgene (human insulin) [H] pSV2gpt.hlns + Michalova Xmv-22 xenotrepic murine leukemia virus-22 JS-6flS-10 Frankel + Frankel Zfp-35 zinc finger protein-35 Zfp35-0.6,Zfp35-2.0,Zfp35-PCR Cunliffe 7Xp35-5, Zfp35-2, Cunliffe Zfp35-1, Zfp35-6 Cunliffe Adra-2 adrenergSc receptor, a-2 [H] pHBHR3 Kobilka Yang-Feng Adrb- 1 adrenergic receptor, I~-1 [H] 131-AR genomic Frielle Yang-Feng Ahd-2 aldehyde dehydrogenase-2, cytoplasmic pG121 Rongnoparut + co:S Weaver Cntf ciliary neuretrophic factor pCMV6 + co:P Masiakowski Cyp2c cytechrome P450, 2c, phenobarbitol inducible [R] pTF-1 + Meehan Friedberg + co:T Friedberg pM8-1 + Meehan pPBS-21, pPB3-15 Meehan Cyp17 cytochrome P450, 17 [R] P455-17a cDNA Fevold 17a-hydroxylase/C17-20 lyase P450 17a cDNA + Youngblood Dl9Cosl DNA segment, Chr 19, Costantini-1 p2351 + co:F Costantini "D 19H42" DNA segment, Chr 19, H42 cosmid H42 Boyle "D19M cC 1" DNA segment, Chr 19, McClelland-1 AP-PCR oligo KB + co:M McClelland Dl9Ndsl DNA segment, Chr 19, Nuffield Dept Surg-1 MUSSDS6 (microsat) + co:JA Todd D19Rp19 DNA segment, Chr 19, Roswell Park-19 pMK1711 + 1-Elliott Emv-22 endogenous ecotropic MuLV-22 pEco Chattopadhyay pEc-B4 Chan pEco, pEc-B4 + Taylor Fth ferritin, heavy chain unnamed cDNAs Torti Yoshitaka BALB-cDNA Yachou [R] Fth DNA Krawetz + co:SA Krawetz pMHFA1 Beaumont Yachou Gin-1 Gross passage A viral integration region-1 GI9-C4, GI9-C3, SS8 Villemur GI9-C 10,GI9-C8,GI9-C 12 Villemur kL985C, kLH81C,kL982C Villemur Gnb-psl guanine nucleotide binding protein, [H] Gnb cDNA Sparkes I~1 pseudogene [H] Gnb cDNA~ Amatruda Blatt His-2 hematopoetic insertion site-2 ~.1.1 + co:JN Ihle Ide insulin-degrading enzyme [H] IDE cDNA Affholter Lpc- 1 lipocortin-1 Lpc-1 cDNA Sakata 3.BWB3 + Horlick J]ipolg, 5qipol4, 3'lipol7 Horlick Ly-1 lymphocyte antigen-1 [=human CD5] GL1-4.2.1, CS-6.1,MD-10 co:Herzenberg pMD10 + co:LA Herzenberg + co:LA Herzenberg Ly-44 lymphocyte antigen-44 [=human CD20] pmBl-1, pmB1-3 Tedder pmBl-1 + co:TF Tedder "Mns-19" minor satellite Chr 19 (centromeric) pMR150 Voliva co:VM Chapman co:ND Hastie Osbp oxysterol binding protein [H] pB+2.5 + Levanon Pax-2 paired box homeotic gene-2 Pax-2 cDNA + Dressler c31A, cPX Dressler Pdhal pyruvate dehydrogenase E l a like [H] E l a subunit cDNA Brown Brown mPDHA2:4 co:W Hutchison Pomc-2 pro- opiomelanocortin -]3 L137,pMKSU16 Uhler, Herbert ME- 150 + co:ATCC [R] pSP-I13 Chen + co:JL Roberts Pygm muscle glycogen phosphorylase [R] M-GPI Hwang + Glaser [R] B-GPI + Glaser Rbp-4 retinol binding protein-4, plasma [R] pPJap-2 + co: BC Laurent +

18 18 18 18 18 19 19 19 19 19

19 19 19 19 19 19 19 19

19

19

19 19 19

19

19 19 19 19 19 19

19

19

Refexe~xme

Nature 1986; 323;226 refiBuehberg, Genetics 1989; 122:153 ref:Sundare~n, Sore Cell Mol Gen 1989;15:367 Gene 1991; 108:285 J Virol 1989; 63:3810 Mamm Genome 1992; 2:110 ref:Sakaguchi, Genomics 1992; 12:151 PNAS 1992; 89:499 Hum Genet 1988; 8~.247 J Virol 1989; 63:1763 Genetics 1990; 124:221 EMBOJ 199~, ~.197 Genomics 1990; 8:331 Genomies 1990; 8:331 Science 1987; 238:650 PNAS 1990; 87:1516 PNAS 1987; 84:7920 PNAS 1990; 87:1516 Genome 1988; Supp 1:107 tel:Bond, Alcohol & Alcoholism 1990; 25:385 ref:Kaupmann, Eur J Neuroeci 1991; 3:1182 PNAS 1988; 85:2662 Biochemistry 1986; 25:7975 ref:Knight, Mol Cell Probes 1990; 4:497 PNAS 1988; 65:2662 PNAS 1988; 85:2662 Mol Endocrinol 1989; 3:968 Genomics 1991; 10:270 re,Justice, Genetics 1990; 125:855 Genornics 1992; 12:106 ref:Welsh, Nucl Acid Res 1991; 19:5275 ref:Hearne, Mamm Genome 1991; 1:273 Mouse News Letter 1988; 80:180 PNAS 1980; 77:5774 PNAS 1980; 77:5579 Genomics 1989; 5:221 J Biol Chem 1988; 263:12638 Nucl Acid Res 1988; 1@10373 Nucl Acid Res 1989; 17:8005 DNA 1986; 5:427 ref: Glaser, Genomics 1989; 5:510 J Biol Chem 1989; 264:7498 Genomics 1991; 9:204 Mol Cell Biol 1987; 7:512 Mol Cell BioI 1987; 7:512 Mol Cell Biol 1987; 7:512 Cytogenet Cell Genet 1985; 46:696 ref:Fong, PNAS 1987; 84:3792 PNAS 1988; 85:7642 ref:Aakew, Oncogene 1991; 6:2041 Mol Endocrinol 1990; 4:1125 Nucl Acid Res 1988; 16:11818 Genomics 1991; 10:365 Genomics 1991; 10:365 ref:Huang, PNAS 1987; 84:204 ref: Glaser, Genomics 1989; 5:510 ref:Kaupmann, Eur J Neurosci 1991; 3:1182 J Immunol 1988; 141:4388 ref:Watanabe, Biochem Genet 1991; 29:325 Nucl Acid Res 1983; 11:8847 ref:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1963; 11:6965 Genomics 1990; 7:65 Development 1988; 104 (supp):181 Development 1990; 109:787 Cytogenet Cell Genet 1989;, 51:970 Somatic Cell Mol Genet 1990; 16:487 ref:Takekubo, Exp Cell IRes 1992; 199:39 J Biol Chem 1983; 258:9444 ref:Kaupmann, Eur J Neurosci 1991; 3:1182 PNAS 1983; 80.'2211 ref: Glaser, Genomics 1989; 5:510 E u r J Biochem 1965; 152:267 Genomics 1989; 5:510 Genomios 1989; 5:510 ref: Chainani, Genomics 1991; 9:376 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

408 Table 3. Continued. On~ Symbola

19 ]9 ]9

~

Name

Rln relaxin Rnu3b-ps6 U3B small nuclear RNA-3 pseudogene 6 Tdt terminal deoxynucleotidyl transferase

Pmbob

Rln A chain probe P, probe U pTdT2O

R F L V c Contac~

+

+

Fowler Mazan Landau Yang-Feng co:NR Landeau Watanabe Watanabe

+ +

Rettenborg Frankel co:MA Martin

+ Tdt genomic Tdt probe

19 Top-1 19 Xmv-18 19 Xmmv-42 X "Als0" X Ags

Alas-2

Amel

X

Ar

Ara f

Bkm-2 Bkm-3 Bmp2b-2 Cbx-rs i Ccg-1

X

Cdr

X

Cf-8

X

Cf-9

topoisomerase 1 (may be on Chr 16) Top genomic xenotropic murine leukemia virus-18 JS-6flS-10 xenotropic-MCF leukemia virus-42 pXenv ts A1S9 defective DNA replication gene (see Ube-1) a-galactosidase [H] ).AG18

+ + + + +

ce:DF Bishop co:DF Bishop co:DF Bishop [H] R989 co:R Fenwick Herman Schoehaut aminolevulinate acid synthase-2, erythroid pMLS-1, pMS20 Schoehaut pMS6, pMS12 Schoenaut MO, ).12, ~.1, k5 Snead amelogenin pMaS-5 co:ML Snead + Chapman + co:SDM Brown pGEM17-2 + co:ML Snead [I-I]87-4a Nakahori [H] pMCVAR Lubahn androgen receptor (Tfm) + co:Lubahn + co:E Wilson + co:E Wilson + co:E Wilson + co:E Wilson mAR1, mARg, He He mARpa(PCR),mARpb(PCR) He He mARpc(PCR) He He mAR2, mAR56 Gaspar Ar-PCR Charest clones 5'mAR, 15A, 19A Faber clones 18A, 15B, 6B, 3A, 1A Faber mA- ra f Huebner raf-related oncogene p19-1 Huleihel, Rapp + Avner + co:UR Rapp + co:UR Rapp Araf probe co:Oncor [D] pCS316 co:KW Jones banded krait minor satellite DNA-2 [D] pCS316 co:KW Jones banded krait minor satellite DNA-3 mMBP2b.7.456 Wozney bone morphogenetic protein 2b-2 + co:Wozney M31 cDNA + ho SDM Brown chromobox related sequence 1 p3962 + co:A Ashworth [Ha] CCG1 + co:T Nishimoto cell cycle, G1 phase defect + co:T Nishimoto [H] pUC462 co:T Nishimoto + co:T Nishimoto [H]kCDR34,[H]pCDR13 Chen cerebellar degeneration-related antigen mCDR19,mCDR20,mCDR35, Chen mCDR65, mCDR68 Chen [H] I:~DR-9 + co:G Sutherland [H] p61-51 + co:Knopf coagulation factor VIII + co:Knopf [H] p114.12 + 5-Lawns [H] pKpn-sac (=pKPN) + co:Genetics Inst + co:Genetics Inst co:Genetics Inst Toole [H] FSA + co:Lawns + Ryder-Cook [H] hs7 + co:Nathans [H] FIX + co:P Avner coagulation factor IX Mandel + co:JL Mandel [H] pKT218 + co:McGraw + co:McGraw

Referencee

FEBS Lett 1991; 292:183 Cytogenet Cell Genet 1991; 56:18 PNAS 1984; 81:5836 Cytogenet Ceil Genet 1986; 43:121 refi Glaser, Genomics 1989; 5:510 Biochem Genet 1991; 29:325 Biochem Genet 1991; 29:325 HGM1991; 11: 191, abstr 2723 J Virol 1989; 63:1763 refiWejman, J Virol 1984; 50:237 ref:MuUins, Genomics 1988; 3:187 ref:Disteche, Genomics 1989; 5:177 ref:Chapman, Genomics 1991; 10:23 ref:Herman, Genomics 1990; 7:307 Genomics 1991; 9:670 Gene 1986; 48:55 Gene 1986; 48:55 Nucl Acid Res 1989; 17:7013 BBRC 1985; 129:812 ref:Lau, Genomics 1989; 4:162 Genomics 1991; 10:23 ref:Hamvas, Mamm Genome 1991; 2:72 ref:Kay, Genomics 1991; 11:651 Genomice 1991; 9:264 Science 1988; 240:327 ref:Mitchell, Genetics 1989; 121:803 ref:Keer, Genomics 1990; 7:566 ref:Brockdorff, Genomics 1991; 10:17 ref:Brockdorff, Mamm Genome 1991; 1:152 ref:Cattanach, Cytogenet Cell Gen 1991; 56:137 BBRC 1990;, 171:697 Nucl Acid Res 1991; 19:2373 BBRC 1990; 171:697 Nucl Acid Res 1991; 19:2373 BBRC 1990; 171:697 Nucl Acid Res 1991; 19:2373 Mol Endocrinol 1990; 4:1600 Mol Endocrin 1991; 5:573 Biochem J 1991; 278:269 Biochem J 1991; 278:269 PNAS 1986; 83:3934 Mol Cell Biol 1986; 6:2655 Somatic Cell Mol Genet 1987; 13:267 ref:Amar, Genomies 1988; 2:220 ref:Grant, Oncogene 1991; 6:397 ref:Storm, Oncogene 1990; 5:345 ref:Kiel-Metzger, NEJM 1985; 313:242 ref:Kiel-Metzger, NF_2M 1985; 313:242 Science 1988; 242:1528 ref:Dickinson, Genomics 1990; 6:505 ref:Hamvas, Mamm Genome 1991; 2:72 ref:Kay, Genomics 1991; 11:651 ref:Keer, Genomics 1990; 7:566 ref:Brockdorff, Genomics 1991; 10:17 ref:Sekiguchi, EMBO J 1988; 7:1683 ref:Cattanach, Cytogenet CellGen 1991; 56:137 PNAS 1990; 87:3077 PNAS 1990; 87:3077 PNAS 1990; 87:3077 ref:Laval, Genornics 1992; 12:818 ref:Mullins, Genomics 1988; 3:187 ref:Disteche, Genomics 1989; 5:177 ref:Avner, Trends in Genetics 1988; 4:18 ref:Herman, Genomics 1990; 7:307 ref:Herman, Genomics 1991; 9:670 tel:Faust, Genomics 1991; 11:154 Nature 1984; 312:342 ref:Amar, Genomics 1988; 2:220 EMBO J 1988; 7:3017 ref:Amar, Genomics 1988; 2:220 PNAS 1987; 84:1629 ref:Cameurio, Nature 1983; 306:701 ref:Amar, Genomics 1988; 2:220 ref:Mullins, Genomics 1988; 3:187 ref:Disteche, Genomics 1989; 5:177 Continued on next p a g e

J.T. Eppig: Clones and Probes

409

Table 3. Continued. Chr Symbola

X

X

Cf-9

Cybb

Locus Name

coagulation factor IX

cytochrome b-245, ~ polypeptide

Probeb

RFLW Centactd

[H] F9

Camerino

BcfiX cDNA MMFIX (microsat) MMFIX (microsat) [H] hs7

+ + +

4CA X

Dmd

Duchenne muscular dystrophy locus seq

MC2-6 MC356-4 [H] Dmd cDNA [H] FSM-5 [H] pCA1

Takahashi Takahashi Takahashi Takahashi

Nature 1983; 306:701 refiHerman, Genomics 1990; 7:307 Genomics 1991; 9:670 Genomics 1992; 12:814 Gene 1990; 86:275 ref:Hearne, M a m m Genome 1991; 1:273 ref:Montagutelli, M a m m Genome 1991; 1:255 Trends in Genetics 1988; 4:18 Science 1986; 232:193 Nature 1986; 322:32 ref:Mullius, Genomics 1990; 7:19 Ryder-Cook, EMBO J 1988; 7:3017 Science 1987; 238:347 Somatic Cell Mol Genet 1987; 13:671 ref:Disteche, Genomics 1989; 5:177 ref:Evans, Mouse Genome 1990; 86:259 Trends in Genetics 1987; 3:33 Nature 1987; 328:166 ref:Kay, Genomics 1991; 11:651 EMBO J 1987; 6:3277 Genomics 1988; 3:337 EMBO J 1988; 7:3017 Genomics 1988; 3:337 EMBO J 1968; 7:3017 EMBO J 1988; 7:3017 EMBO J 1988; 7:3017 EMBO J 1988; 7:3017 Science 1988; 239:1416 ref:Herman, Genomice 1990; 7:307 Genomics 1991; 9:670 Science 1989; 244:1578 Science 1989; 244:1578 Science 1989; 244:1578 Science 1989; 244:1578 Science 1989; 244:1578 Science 1969; 244:1578 Science 1989; 244:1578 ref:Laval, Genomics 1992, 12:818 Devel 1987; 101 (supp ~. 177 Nucl Acid Res 1987; 15:2959 Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321

Takahashi

Devel Growth & Differ 1990; 32:321

Takahashi Takahashi Takahashi Takahashi Herman Herman Herman Herman Herman Herman Herman Herman Herman Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Broekdorff

Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321 Devel Growth & Differ 1990; 32:321 Genomics 1991; 10:961 Genomics 1991; 10:961 Genomics 1991; 10:961 Genornics 1991; 10:961 Genomics 1991; 10:981 Genornics 1991; 10:961 Genomics 1991; 10:961 Genomics 1991; 10:961 Genomics 1991; 10:961 Genomics 1990; 7:573 ref:Keer, Genomice 1990; 7:566 Genomics 1991; 10:17 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 ref:Keer, Genomics 1990; 7:566 Genemics 1991; 10:17

co.'JL Mandel Herman Herman Wu co:JA Todd co:JA Todd co:P Avner Nathans Royer-Pokora co:S Orkin co: S Orkin Hoffman Chamberlain

co:LM Kunkel co:LM Kunkel Monaco Brockdorff co:K Davies

[H] pCalb

[HI pD38 [H] prOaes 67, 60, 71, 73, + [I-I] probes 75, 77-2, + [H] probes 77-3, 77-1 + pXD4, pXD1 +

Cress Cavanna Ryder-Cook Cavanna Ryder-Cook Ryder-Cook Ryder-Cook Ryder-Cook Chamberlain co:J Chamberlain Herman

pxI)4 + MAD22,MAD 18,MAD19-2, S i e i n s k i MAD23,MAD 4-1,MAD 10, S i c i n s k i MAD4-2,MAD1,MAD21, Sicinski M A D 2 7 ,MAD29 ,MAD26,

X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X X

MAD25,MAD28,MAD36-1, MAD36-2,MAD50,MAD47, MAD51,MAD48,MAD34-4 [H]Cf23a + "DX?" DNA segment, testis specific probe PL10 "DX?" DNA segment, nonstringent hybridization pYMT2/B "DXIJpn?" DNA segment, Chr X, NIH, Japan-1 clone 7-1 "DX2Jpn?" DNA segment, Chr X, NIH, Japan-2 clone 7-2 "DX3Jpn?" DNA segment, Chr X, NIH, Japan-3 clone 13 "DX4Jpn?" DNA segment, Chr X, NIH, Japan-4 clone 74-1 "DX5Jpn?" DNA segment, Chr X, NIH, Japan-5 clone 123-1 "DX6Jpn?" DNA segment, Chr X, NIH, Japan-6 clone 144-1 "DX7Jpn?" DNA segment, Chr X, NIH, Japan-7 clone 144-2 "DX8Jpn?" DNA segment, Chr X, NIH, Japan-8 done 201 "DX9Jpn?" DNA segment, Chr X, NIH, Japan-9 clone 208 "DX10Jpn?" DNA segment, Chr X, NIH, Japan-10 clone 221 "DXllJpn?" DNA segment, Chr X, NIH, J a p a n - l l clone 226-1 "DXl2Jpn?" DNA segment, Chr X, NIH, Japan-12 clone 226-2 "DX13Jpn?" DNA segment, Chr X, NIH, Japan-13 clone 261 DXBayl DNA segment, Chr X, Baylor-1 8.1F2 DXBay2 DNA segment, Chr X, Baylor-2 8.1F3 DXBay3 DNA segment, Chr X, Baylor-3 8.1F4 DXBay4 DNA segment, Chr X, Baylor-4 8.1F5 DXBay5 DNA segment, Chr X, Baylor-5 8.1F6 DXBay6 DNA segment,Chr X, Baylor-6 8.1F6 DXBay7 DNA segment,Chr X, Baylor-7 8.1F7 DXBay8 DNA segrnent,Chr X, Baylor-8 8.1F8 DXBay9 DNA segment,Chr X, Baylor-9 8.1F9 DXCrcl3 DNA segment,Chr X, Clinical Res Ctr-13 EM13 + pEM13C + DXCrcl4 DNA segment,Chr X, Clinical Res Ctr-14 EM14 DXCrc15 DNA segment,Chr X, Clinical Res Ctr-15 EM15 DXCrcl6 DNA segment,Chr X, Clinical Res Ctr-16 EM16 DXCrc21 DNA segment,Chr X, Clinical IRes Ctr-21 EM21 DXCre22 DNA segment,Chr X, Clinical Res Ctr-22 EM22 DXCrc23 DNA segment,Chr X, Clinical Res Ctr-23 EM23 DXCrc24 DNA segment,Chr X, Clinical Res Ctr-24 EM24 DXCrc25 DNA segment,Chr X, Clinical Res Ctr-25 EM25 DXCrc28 DNA segment,Chr X, Clinical Res Ctr-28 EM28 +

~.EM28A

+

Sicinski

Sicinski Sicinski Sieinski

co:D Love Leroy Bishop Takahashi Takahashi Takahashi Takahashi

Continued on next page

410

J.T. Eppig: Clones and Probes

Table 3. Continued. C~r

Syrdda

~u~

X X X X X

DXCrc32 DXC~40 DXC~ DXCrc~ DXC~47

DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical

Res Res Res Res Res

Ctr-32 Ctr-40 Ctr-42 Ctr-43 Ctr-47

X X X X X X

DXC~48 DXC~49 DXC~50 DXCm51 DXCrc53 DXC~57

DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical

Res Pes Pes Res Res Res

Ctr-48 Ctr-49 Ctr-50 Ctr-51 Ctr-53 Ctr-57

X X X

DXCrc~ DXC~73 DXCrc94

DNA segmenLChr X, Clinical Res Ctr-63 DNA segment,Chr X, Clinical Res Ctr-73 DNA segment,Chr X, Clinical Res Ctr-94

X X

DXCm95 DXCrc98

D N A segment,Chr X, Clinical Res Ctr-95 D N A segment,Chr X, Clinical Res Ctr-98

X X X X X

DXCrc99 DXCrcl01 DXCrcl03 DXCrcl04 DXCrcll2

DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical

Res Pea Res Res Res

Ctr-99 Ctr-101 Ctr-103 Ctr-104 Ctr-112

EM99 EM101

X X X X

DXCrc117 DXCrcl20 DXCrr DXCYcl31

DNA aegmant,Chr X, DNA segment,Chr X, DNA segment,Chr X, DNA segment,Chr X,

Res Pes Pea ires

Ctr-117 Ctr-120 Ctr-128 Ctr-131

EMll7

X X X X

DXCrc134 DXCrc138 DXCrc139 DXCrcl40

DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical

X X X X X X X X

DXCrc142 DXCrc146 DXCrc149 DXCrc153 DXCrc157 DXCrc159 DXCrc162 DXCrc169

DNA DNA DNA DNA DNA DNA DNA DNA

Name

Probeb

Clinical Clinical Clinical Clinical

Res Ctr-134 Res Ctr-138 ires Ctr-139 Res Ctr-140

EM32 EM40 EM42 EM43 EM47 pEM47A EM48 EM49 EMS0 EM51 EM53 EM57 pEM57A EM63 EM73 EM94 pEM94A EM95 EM98 pF,M98B

F..M103

EM104 EMll2 pEM 112A EM120 EM128 EMI31 pEM131A EM134 EM138 EM139 EM140 pEM140A

pEIVII40 segment,Chr X, segment,Chr X, segment,Chr X, segment,Chr X, segment,Chr X, segment,Chr X, segment,Chr X, segment,Chr X,

ClinicaliresCtr-142 ClinicalRes Ctr-146 ClinicalIResCtr-149 ClinicalPea Ctr-153 ClinicalPea Ctr-157 ClinicalPea Ctr-159 ClinicalRes Ctr-162 ClinicalPes Ctr-169

EM142 EM146 EM149 ~153 EMI57

EMI59 EM162 F.M169 pEM169A

X X

DXCrcl70 DXCrcl71

D N A segmentoChr X, ClinicalRes Ctr-170 EMI70 D N A segment,Chr X, ClinicalRes Ctr-171 EM171 pEM171A

X X X X

DXCrc172 DXCrc173 DXCrc174 DXCrcI77

DNA segment,Chr X, Clinical DNA segment,Chv X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical

Res Res Res Res

Ctr-172 Ctr-173 Ctr-174 Ctr-177

X X X

DXCrcl80 DXCrcl81 DXCrc187

D N A segment,Chr X, ClinicalRes Ctr-180 D N A segment,Chr X, ClinicalRes Ctr-181 D N A segment,Chr X, ClinicalRes Ctr-187

X

DXCrclg0

DNA segment,Chr X, Clinical Res Ctr-190

X X X X

DXCrc192 DXCrc194 DXCr~01 DXCrc202

DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical

Res Res Res Res

X X X X X X

DXCrc204 DXCrc301 DXCrc306 DXCrc309 DX~r310 DXCrc311

DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segrnent,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical DNA segment,Chr X, Clinical

Res Ctr-204 Res Ctr-301 Res Ctr-306 Res Ctr-309 Res Ctr-310 Res Ctr-311

Ctr-192 Ctr-194 Ctr-201 Ctr-202

EM172 EM173 F.,M174 EM177 pEM177B EM180 EM181 EM187 pEM187A EM190 XEM190E EM192 EM194 EM201 F_,M202 pEM202B EM204 NM10 NM6 NM9 NM10 NMll

P~LVc C~t

d

Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff

P~f~

Genomics 1990; 7:573 Genomica 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1991; 10:17 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1991; 10:17 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1991; 10:17 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomica 1991; 10:17 Genomics 1990; 7:573 Genomics 1990; 7:573 Genornics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1991; 10:17 Genolnics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1991; 10:17 Mamm Genome 1991; 1:152 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1991; 10:17 Mamm Genome 1991; 1:152 Genomics 1990; 7:573 Genomica 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 ref:Keer, Genomics 1990; 7:566 Genomics 1991; 10:17 Mamm Genome 1991; 1:152 Genomics 1990; 7:573 Genomics 1990; 7:573 ref:Keer, Genomics 1990; 7:566 Genomics 1991; 10:17 M a m m Genome 1991; 1:152 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1991; 10:17 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1991; 10:17 Genomics 1990; 7:573 Genomics 1991; 10:17 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomica 1991; 10:17 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomica 1990; 7:573 C o n t i n u e d on n e x t p a g e

411

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Syml~a

X X X X

DXCrc314 DXC~v.315 DXCYc316 DXCrc318

LocusName

X

X

DXPas2

DNA segment, Chr X, Pasteur Institute-2

probe 52 (or MDSX2)

X

DXPas3

DNA segment, Chr X, Pasteur Institute-3

probe 66 (orM S D X 3 )

X

X

DXPas4 DXPas5

DNA segment, Chr X, Pasteur Institute-4 DNA segment, Chr X, Pasteur Institute-5

probe 87 (orMSDX4) probe 100 (orM S D X 5 )

X X X

DXPas6 DXPas7 DXPas8

(withdrawn, = DXS144Eh) (withdrawn, = DXS32h) DNA segment, Chr X, Pasteur Institute-8

[H] probe St14-1

X X X X X

Clinical Clinical Clinical Clinical

RFLVc C~nI~"d

NM14 NM15 + NM16 NM18 pNM18A + DXCrc323 DNA segment,Chr X, Clinical ires Ctr-323 NM23 pNM23A + DXCrc323A DNA segment,Chr X, Clinical IRes Ctr-323A DXCrc323 linking clone DXCrc323B DNA segment,Chr X ,Clinical Res Ctr-323B DXCrc323 linking clone DXC~66 DNA segment,Chr X, Clinical Res Ctr-366 NM66 DXNds3 DNA segment, Chr X, Nuffield Dept ofSurg-3 MMCCE (microsat) + (microsa0 DXOfll DNA segment, Chr X, Orleans-1 B17, B6, B52, B25 (long mosaic repetitive sequence) DXPasl DNA segment, Chr X, Pasteur Institute-1 probe 45 (or MSDX1)

X

DNA segment,Chr X, DNA segment,Chr X, DNA segment,Chr X, DNA segment,Chr X,

Probeb

Res Ctr-314 Res Ctr-315 IRes Ctr-316 ires Ctr-318

PCR probe 21.10 PCR probe 21.11 PCR probe 21.11

Simmler Simmler Simmler

Genomics 1991; 10:770 Genomics 1991; 10:770 Genomics 1991; 10:770

PCR probe 21.12 PCR probe 21.21 PCR probe 68.14 PCR probe 68.14

Simmler $immler Simmler Simmler

Genomics 1991; Genomics 1991; Genomics 1991; Genomics 1991;

PCR probe 68.23

Simmler

Genomics 1991; 10:770

XDXPas8A pDXP8B.1, ~.DXPas8B probe 80 (or MDFXY)

X X X

DXPas9 DXPasl0 DXPas 11

DNA segment, Chr X, Pasteur Institute-9 DNA segment, Chr X, Pasteur Institute-10 DNA segment, Chr X, Pasteur Institute-ll

X X

DXPasl2 DXPas 13

DNA segment, ChrX, Pasteur Institute-12 DNA segment, Chr X, Pasteur Institute-13 [H] CCR1

+ + +

+

+ +

X

DXPasl4

DNA segment, Chr X, Pasteur Institute-14 [HI E87-25

X

DXPasl5

DNA segment, Chr X, Pasteur Institute-15 [HI p212

X X X

DXPasl7 DXPas 18 DXPasl9

X

DXPas20

DNA segment, Chr X, Pasteur Institute-17 CP8.6 DNA segment, Chr X, Pasteur Institute-18 L9 DNA segment, Chr X, Pasteur Institute-19 Lll Lll-6 DNA segment, Chr X, Pasteur Institute-20 [H] CX52.5

X X

DXPas21 DXPas22

see Cf-8 DNA segment, Chr X, Pasteur Institute-22 [H] OR5

+ + + +

+ + + + + +

+ +

X

refiAmar, EMBO J 1985; 4:3695 ref.'Amar, Genomics 1988; 2:220 reflDickinson, Genondcs 1990; 6:505 refiDerry, Genomics 1991; 10:593 refiHerman, Genomics 1991; 10:961 refiMaconochie, Mamm Genome 1991; 2:64 ref:Hamvas, Mamm Genome 1991; 2:72 refiAnmr, EMBO J 1985; 4:3695 ref:Amar, Genomics 1988; 2:220 ref:Ryder-Cook, EMBO J 1988; 7:3017 ref:Herman, Genomics 1991; 10:961 ref.'Amar, EMBO J 1985; 4:3695 ref:Siracusa, Genetics 1991; 127:169 ref:Herman, Genomics 1991; 10:961 ref.'Amar, EMBO J 1985; 4:3695 ref:Amar, EMBO J 1985; 4:3695 ref:Amar, Genomics 1988; 2:220

Avner Avner Avner Avner Avner Avner Avner Avner Avner Avner Avner Avner Avner Avner Avner Avner Avner

ref:Avner, Trends in Genetics 1988; 4:18 ref:Amar, Genomics 1988; 2:220 Cytogenet Cell Genet 1991; 56:137 Mamm C-enome 2 1991; 2:21 Genomics 1991; 10:770 Genomics 1991; 10:770 Genomics 1991; 10:770

+

X X X X

co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR co:PR

co:PR Avner co:Bishop Cattanach Sefton Simmler Simmler Simmler

+

X X X

Genomics 1990; 7:573 Genomica 1990; 7:573 Genomics 1990; 7:573 Genomics 1990; 7:573 Genomics 1991; 10:17 Genomics 1990; 7:573 Genomics 1991; 10:17 Mammal Genome 1991; 1:78 Mammal Genome 1991; 1:78 Genomics 1990; 7:573 ref:Hearne, Mamm Genome 1991; 1:273 ref:Montagutelli, Mamm Genome 1991; 1:255 ref:Decoville, Mamm Genome 1992; 2:172

PNAS 1985; 82:2824 PNAS 1987; 84:1629 ref:Anmr, Genomics 1988; 2:220 ref:Herman, Genomics 1990; 7:307 Genomics 1991; 9:670 ref:Faust, Genomics 1991; 11:154 ref:Faust, Genomics 1991; 11:154 ref:Avner, Trends in Genetics 1988; 4:18 ref:Avner, Trends in Genetics 1988; 4:18 ref:Avner, Trends in Genetics 1988; 4:18 Genet Res 1990; 56:163 ref:Avner, Trends in Genetics 1988; 4:18 Heilig: Nature 1987; 328:168 ref:Amar, Genomics 1988; 2:220 Science 1986; 226:1447 ref:Heilig, Nature 1987; 328:168 ref:Anmr, Genomics 1988; 2:220 ref:Avner, Trends in Genetics 1988; 4:18 ref:Amar, Genomics 1988; 2:220 Trends in Genetics 1988; 4:18 Trends in Genetics 1988; 4:18 Trends in Genetics 1988; 4:18 Cytogenet Cell Genet 1991; 56:137 ref:Avner, Trends in Genetics 1988; 4:18 ref:Amar, Genomics 1988; 2:220

+

DXPas23 DNA segment, Chr X, Pasteur Institute-23 DXPas25 DNA segment, Chr X, Pasteur Institute-25 "DXPas?-I" DNA segment, Chr X, Pasteur Institute-? "DXPas?-2" DNA segment, Chr X, Pasteur Institute-? "DXPas?-3" DNA segment, Chr X, Pasteur Institute-? (probe 10.15 recognizes 2 loci) "DXPas?-4" DNA segment, Chr X, Pasteur Institute-? "DXPas?-5" DNA segment, Chr X, Pasteur Institute-? "DXPas?-6" DNA segment, Chr X, Pasteur Institute-? (probe 21.11 recognizes 2 loci) "DXPas?-7" DNA segment, Chr X, Pasteur Institute-? "DXPas?-8" DNA segment, Chr X, Pasteur Institute-? "DXPas?-9" DNA segment, Chr X, Pasteur Institute-? "DXPas?-10" DNA segment, Chr X, Pasteur Institute-? (probe 68.14 recognizes 2 loci) "DXPas?-I r DNA segment, Chr X, Pasteur Institute-?

Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Brockdorff Norris Norris Brockdorff co~A Todd co:JA Todd co:D Locker

co:JL Mandel,Oberle Avner co:JL Mandel co:ATTC Herman co:GE Herman co:GE Herman co:Bishop co:Bishop co:Bishop Guenet co:Bishop co:PR Avner co:Mandel Worton co:Mandel co:Mandel co:Pearson co:Bhattacharya co:PR Avner co:PR Avner co:PR Avner Cattanach co:Pearson co:Pearson

+

X X X X X

Refe~mncee

6/1 probe I 0 ~ PCR probe 10.3 P C R probe 10.15 PCR probe 10.15

+

10:770 10:770 10:770 10:770

C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

412 Table 3. Continued. Ch~ Syrabda

X X X

LocusName

Probeb

X X X X X X

"DXPaa?-12" DNA segment, Chr X, Pasteur Institute-? "DXPas?-13" DNA segment, Chr X, Pasteur Institute-? "DXPas?-14" DNA segment, Chr X, Pasteur Institute-? (probe 125.20 recognizes 2 loci) "DXPas?-15" DNA segment, Chr X, Pasteur Institute-? "DXPasT-16" DNA segment, Chr X, Pasteur Institute-? "DXPas?-17" DNA segment, Chr X, Pasteur Institute-? (probe 125.4 recognizes 3 loci) "DXPas?-IS" DNA segment, Chr X, Pasteur Institute-? "DXPas?-19" DNA segment, Chr X, Pasteur Institute-? "DXPas?-20" DNA segment, Chr X, Pasteur Institute-? "DXPas?-21" DNA segment, Chr X, Pasteur Institute-? "DXPas?-22" DNA segment, Chr X, Pasteur Institute-? DXS144Eh DNA segment, Chr X, human DXS144E

X

DXS253Eh

X

DXS254Eh DNA segment, Chr X, human DXS254E

X X

DXS296h DXS32h

DNA segment, Chr X, human DXS296 DNA segment, Chr X, human DXS32

X X X

DXSmh7 DXSmh9 DXSmhl0

DNA segment, St. Mary's Hospital-7 DNA segment, St. Mary's Hespital-9 DNA segment, St. Mary's Hospital-10

X X

DXSmh14 DXSmhl5

DNA segment, St. Mary's Hospital-14 DNA segment, St. Mary's Hospital-15

X X

DXSmh23 DXSmh36

DNA segment, St. Mary's Hospital-23 DNA segment, St. Mary's Hespital-36

X

DXSmh43

DNA segment, St. Mary's Hospital-43

X

DXSmh44

DNA segment, St. Mary's Hespital-44

X X X X X X X X

DXSmh59 DXSmh64 DXSmh66 DXSmh67 DXSmh91 DXSmh93 DXSmhll7 DXSmhl20

DNA segment, DNA segment, DNA segment, DNA segment, DNA segment, DNA segment, DNA segment, DNA segment,

X X

DXSmh129 DNA segment, St. Mary's Hospital-129 DXSmhl41 DNA segment, St. Mary's Hospital-141

X

DXSmh172 DNA segment, St. Mary's Hospital-172

X

DXSmhl91 DNA segment, St. Mary's Hospital-191

X X X

DNA segment, Chr X, human DXS253E

St. Mary's Hospital-59 St. Mary's Hospital-64 St. Mary's Hospital-66 St. Mary's Hospital-67 St. Mary's Hespital-91 St. Mary's Hospital-93 St. Mary's Hospital-ll7 St. Mary's Hespital-120

RFLVc C ~ t ~

Refimmcee

PCR probe 68.24 PCR probe 125.20 PCR probe 125.20

Simmler Simmler Simmler

Genomics 1991; 10:770 Genomics 1991; 10:770 Genomics 1991; 10:770

PCR probe 125.4 PCR probe 125.4 PCR probe 125.4

Simmler Simmler Simmler

Genornics 1991; 10:770 Genomics 1991; 10:770 Genomics 1991; 10:770

Simmler Simmler Simmler Simmler Simmler Oberle + co:JL Mandel [H] probe cll + co:PR Avner + co: JL Mandel + co: JL Mandel Mandel + co:JL Mandel In] probe c69 § co: JL Mandel Alcalay XP11,~.PgA- 1, XP4A- 1,XP19,kT27-1,kT 17 Alcalay G28A + co:PR Avner,Amar + co:PR Avner co:L Amar G28B + co:PR Avner,Amar + Cavenna + co:PR Avner + co:PR Avner co:PR Avner + co:PR Avner + co:PR Avner co:L Amar + Herman [H] VK21C + co:G Sutherland [H] probe M2C + co'JL Mandel + co:JL Mandel DXSmh7, pAGDY1 + co:Brown DXSmh9, pMKM92 + co:Brown co:SDM Brown DXSmhl0 (MDSX10) + Brockdorff DXSmh14 + co:SDM Brown Nasir DXSmhl5 kbanl 1,kban 14,kban 16,kban 19 Nasir DXSmh23 + co:SDM Brown DXSmh36 (MDRX36) eo:SDM Brown + Brockdorff DXSmh43 (MDSX43) eo:SDM Brown + Brockdorff + co:SDM Brown DXSmh44 (MDSX44) + co:SDM Brown Brockdorff + co:SDM Brown + Brockdorff DXSmh59 + co:SDM Brown DXSmh64 + co:SDM Brown DXSmh66 + co:SDM Brown DXSmh67 + co:SDM Brown DXSmhgl + co:SDM Brown DXSmh93 + co:SDM Brown DXSmhll7 + co:SDM Brown DXSmhl20(MDSX120) + co:SDM Brown Brockdorff + co:SDM Brown + co:SDM Brown DXsmh129 Brockdorff DXSmhl41 (MDRX141) + co:SDM Brown Brockdorff + co:Brown ;q~an11, iLbanl3, khan14 Nasir khan16, 7.ban19 Nasir DXSmh172 (MDSX172) co:SDM Brown + Brockdorff + co:Brown DXSmh191 + co:SDM Brown

PCR PCR PCR PCR PCR Cll

probe 125.5 probe 125.6 probe 125.8 probe 125.18 probe 125.19

Genomics 1991; 10:770 Genomies 1991; 10:770 Genomies 1991; 10:770 Genomics 1991; 10:770 Genomics 1991; 10:770 Hum Gene 1987; 77:60 ref:Herman, Genomics 1990; 7:307 PNAS 1987; 84:5330 ref:Avner, PNAS 1987; 84:1629 ref:Ryder-Ccok, EMBO J 1988; 7:3017 Cold Spr Hbr Symposium 1986; 51:195 ref:Amar, Genomies 1988; 2:220 ref:Avner, PNAS 1987; 84:1629 Nucl Acid Res 1988; 16:9527 Nucl Acid Res 1988; 16:9527 PNAS 1987; 84:1629 ref:Herman, Genomics 1990; 7:307 ref:Filippi, Genomics 1990; 7:453 PNAS 1987; 84:1629 Genomics 1988; 3:337 tel:Herman, Genomics 1990; 7:307 tel:Herman, Genomics 1991; 10:961 ref:Fanst, Genomics 1991; 11:154 ref:Amar, Genomics 1988; 2:220 ref:Ryder-Ccok, EMBO J 1988; 7:3017 ref:Filippi, Genomics 1990; 7:453 Genomics 1991; 9:670 ref:Laval, Genomics 1992; 12:818 Cold Spr Hbr Symposium 1986; 51:195 ref:Amar, Genomics 1988; 2:220 ref:Maconochie, Mamm Genome 1991; 2:64 ref:Maconochie, Mamm Genome 1991; 2:64 ref:Fisher, PNAS 1985; 82:5846 EMBO J 1987; 6:3291 refiBrockdorff, EMBO J 1987; 6:3291 PNAS 1990; 87:399 PNAS 1990; 87:399 refiBrockdorff, EMBO J 1987; 6:3291 refiFisher, PNAS 1985; 82:5846 EMBO J 1987; 6:3291 refiFisher, PNAS 1985; 82:5846 EMBO J 1987; 6:3291 ref:Kay, Genomics 1991; 11:651 ref:Fisher, PNAS 1985; 82:5846 EMBO J 1987; 6:3291 ref:Keer, Genomics 1990; 7:566 Genomica 1991; 10:17 ref:Brockdorff, EMBO J 1987; 6:3291 ref:Brockdorff, EMBO J 1987; 6:3291 ref:Brockdorff, EMBO J 1987; 6:3291 ref:Brockdorff, EMBO J 1987; 6:3291 ref:Brockdorff, EMBO J 1987; 6:3291 ref:Brockdorff, EMBO J 1987; 6:3291 ref:Brockdorff, EMBO J 1987; 6:3291 ref:Fisher, PNAS 1985; 82:5846 EMBO J 1987; 6:3291 ref:Keer, Genomics 1990; 7:566 ref:Hamvas, Mamm Genome 1991; 2:72 EMBO J 1987; 6:3291 ref:Fisher, PNAS 1985; 82:5846 EMBO J 1987; 6:3291 ref:Mullins, Genomics 1990; 7:19 PNAS 1990; 87"~99 PNAS 1990; 87:399 tel:Fisher, PNAS 1985; 82:5846 EMBO J 1987; 6:3291 ref:Mullins, Genomics 1990; 7:19 ref:Brockdorff, EMBO J 1987; 6:3291 Continued on next p a g e

413

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Symbola

LocusName

X

DXSmh219 DNA segment, St. Mary's Hospital-219

X

DXSmh222

X

DXSmh225

X X X

DXSmh255 DXUcsfl DXWasl7

X

DXWas31

X

DXWas68

X

DXWas70

X X

DXWasl07 Fmr-1

X

G6pd

X

Gabra-3

X

Gf-1

X

Gjb-1

X X

Glra2 Hprt

X X X

Htrle Ids Lleam

X

Maoa

X

X

Maob Mef-2

X X

mdx "Mns-X"

X

"Ms6-X"

Probeb

RFLVc C~at~ d

DXSmh219 (MDSX219)

+ co:SDM Brown Brockdorff DNA segment, St. Mary's Hospital-222 DXSmh222 (MDRX222) eo:SDM Brown + Brockdorff DNA segment, St. Mary's Hospital-225 DXSmh225 (MDRX225) eo:SDM Brown + Broekdorff DNA segment, St. Mary's Hospital-255 DXSmh255 + co:SDM Brown DNA segment, U Cal San Francisco- 1 [H] probe A (cos p542) Levinson DNA segment, Univ of Washington-17 probe 17A + co:C Disteche + Disteche + co:C Disteche DNA segment, Univ of Washington-31 probe 31A + 2-Disteche + Disteche + co:C Disteche DNA segment, Univ of Washington-68 probe 68-36 co:C Disteche + Disteche co:C Disteche kbanl3, ~banl4, kbanl6 Nasir DNA segment, Univ of Washington-70 probe 70-38 + co:C Disteche + Disteche Disteche Disteche DNA segment, Univ of Washington-107 [x~be107 eo:C Disteche fragile X mental retardation syn. 1 homolog [H] FMR1 PCR + co:G Sutherland [H] BC22 + eo:Nelson,Pieretti glucose-6-phosphate dehydrogenase-1 [H] pGDP3 Avner + co:Lu~zatto [H] GPD25A Persico + eo:M Persico GABA-A receptor, subunit a3 [H] Gabra-3 + Buckle [13]pbGRa3 + Herman + Herman co:E Barnard + Laval [H] GABA0.7Xba + co:A Hicks globin factor- 1 Gf-1 eDNA co: SH Orkin + co:SH Orkin gap junction membrane channel protein ~1 [H] [31 eDNA Hsieh (conne~dn 32) [R] CX32 Paul Sefton glycine receptor, a2 subunit Glya2.1, Glya2.3 + Derry hypoxanthine-guanine phoshoribosyl pHPT5 eo:Caskey transferase Melton + Ryder-Cook pMEV + co:Johnson Hprt-RT-PCR- 1 + Zinn Hprt-RT/PCR + co:C Disteche pSB1 + Kay MMREPGT4 (microsat) + co:JA Todd (microsat) + Montagutelli (3' region) pHPT2 Brennard (intronl) pHPR~.13-in 1 Lock Jones + co: Lock + Siraeusa 5-hydrexytryptamine (serotonin) lc receptor M1C2.3 Yu iduronate 2 sulfatase [H] pc2S15 + Herman L1 neural cell adhesion molecule pK13 Moos Djabali + Chapman + Herman co:M Schachner clone K21, clone K21-1 Taeke monoamine oxidase A [H] Maoa eDNA + co:JC Shih p2-2-~ + co:Z Chen monoamine oxidase B [HI Maob eDNA + eeOC Shih mcf.2 transforming sequence pMT1 co:D Birnbaum + eo:D Birnbaum + Herman X-linked muscular dystrophy, see Dmd minor satellite Chr X (centromeric) pMR150 Voliva co:VM Chapman co:ND Hastie minisatellite 6-X [HI probe 33.6 Jeffreys

Ref~eace e

ref:Fisher, PNAS 1985; 82:5846 EMBO J 1987; 6:3291 ref:Fisher, PNAS 1985; 82:5846 EMBO J 1987; 6"~291 ref:Fisher, PNAS 1985; 82:5846 EMBO J 1987; 6:3291 ref:Brockdorff, EMBO J 1987; 6:3291 Genomics 1990; 7:1 Cytometry 1982; 2:282 Genomics 1989; 5:177 ref:Gora-Maslak, Mouse Genome 1991; 89:852 Cytometry 1982; 2:282 Genomics 1989; 5:177 ref:Chapman, Genomics 1991; 10:23 Cytogenet Cell Genet 1985; 39:262 Genomics 1989; 5:177 ref:Boyle, Genomics 1992; 12:106 PNAS 1990; 87.'399 Cytogenet Cell Genet 1985; 39:262 Genomics 1989; 5:177 N u d Acid Res 1987; 15:4393 Cytometry 1990; 11:119 Genomics 1989; 5:177 ref:Laval, Genomics 1992; 12:818 ref:Herman, Genomics 1992; 12:814 PNAS 1987; 84:1629 ref:Mullins, Genomics 1988; 3:187 Nuel Acid Res 1986; 14:2511 ref:Herman, Genomics 1990; 7:307 Neuron 1989; 3:647 Genomics 1991; 9:670 Genomics 1992; 12:814 ref:Faust, Genomics 1991; 11:154 Genomics 1992; 12:818 ref:Derry, Genomics 1991; 10:593 ref:Tsai, Nature 1989; 339:446 ref:Chapman, Genomics 1991; 9:309 Sore Cell Mol Genet 1991; 17:191 J Cell Biol 1986; 103:123 Mamm Genome 1992; 2:21 Genomics 1991; 10:593 ref:Konecki, Nucl Acid Res 1982; 10:6763 PNAS 1984; 81:2147 EMBOJ 1988; 7:3017 ref:Mullius, Genomics 1988; 3:187 Genomics 1991; 11:1097 ref:Adler, PNAS 1991; 88:4592 Genomics 1991; 11:651 ref:Hearne, Manana Genome 1991; 1:273 Mamm Genome 1991; 1:255 PNAS 1982; 79:1950 Mol Cell Biol 1986; 6:914 Somatic Cell Mol Genet 1987;13:325 ref: Dickinson, Genomics 1990; 6:505 Genetics 1991; 127:169 Mol Brain Res 1991; 11:143 Genomics 1992; 12:814 Nature 1988; 334:701 Genomics 1990; 7:587 Genomics 1990; 8:113 Genomics 1991; 9:670 ref:Faust, Genomics 1991; 11:154 Neurosci Lett 1987; 82:89 ref: Derry, Nucl Acid Res 1989; 17:8403 refiHerman, Genomics 1991; 10:961 ref: Derry, Nucl Acid Res 1989; 17:8403 ref:Mattei, Cytogenet Cell Genet 1989; 51:1041 tel:Grant, Cytogenet Cell Genet 1990; 54:175 Genomics 1992; 12:814 Nud Acid Res 1983; 11:8847 ref:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Piei~as, N u d Acid Re8 1983; 11:6965 Nucl Acid Res 1987; 15:2823 C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

414 Table 3. Continued. Chr Symhia

X

Mtv-28

X

Odc-rsl3

X

Otc

LocusName

X

MMTV8-21,MMTV8-29 MMTV 8-21 + MMTV 8-290 + ornithine decarboxylase related seq-13 pMK934 + + pODC934 pCR6 (pDOC934 derived) + ornithine transcarbamylase (spf, wildtype) pOTC

Otf3-rs8 Pdha- 1

Otf-3 related sequence-8 pyruvate dehydrogenase Ela subunit

Pfe

properdin factor, complement

Pgk-1

RFLVc Contac~

mammary tumor virus locus-28

ornithine transcarbamylase (spf mutant)

X

Probeb

phosphoglycerate kinase-I

pMOTC [R]pMN152 unnamed [R] pO2~- 1 spMO-3 5' Otf-3 cDNA [H] E l a subunit cDNA mP mP1 P1, P2 kPGKM63, pGKM65b kPGKM63 Pgk pGKM55b [H] probe A (pHPGK7-e)

[HI PGK-7E [HI pMPGK probe E (pMPGKS-b) B12.5, B17, pMPGKS-b pCAB17BH2.5-BF0.5;65 pCA(B17)BH2.SBE0.5 pCAB17

X

Phka

(Pgk-la) (Pgk-lb) phosphorylase kinase, a subunit

[H]BEO5:65 Pgk- la genomic pCAI Phka c D N A [Rab] aPP2

+ + + + + +

+

+

+ + +

+ + +

+ + + +

+ +

[Rab] p~Phk-D1 +

X

Plp

myelin proteolipid protein

~.PLP 1, ~.PLP 2 X23,k28

p-BS-DM-20 [R] p27

X

Pmv- 1

myelin proteolipid protein (wildtype) polytropic murine leukemia virus-1

MMPSP7A (microsat) (microsat) p-23 pJ-31, pJ-81 pC-4 JS-5

X

Pmv-6

polytropie murine leukemia virus-6

JS-5

X X

Pola Rps4x

DNA polymerase, a ribosomal protein $4, X-linked

pMpola pDP1340 Rps4x RT-PCR XFBV41, pDP1340 368bp intmn probe [H] hs7

myelin proteolipid protein (jp mutant)

X

Rsvp

red sensitive visual pigment

+ + + + +

+ + + +

+ + + + + +

+ ~gMM25

Majors Eicher Eicher 1-Elliott Stephenson co:Berger Rheaume eo:FG Berger Veres Veres co:CT Caskey co:CT Caskey co:CT Caskey eo:CT Caskey co:CT Caskey co:CT Caskey co:Caskey Veres Takiguchi Ohtake Hodges Siracusa Brown Brown Evans Evans Goundis Mori Cavanna co:SDM Brown Goto co:Michelson co:Michelson co:AM Michelson co: SH Orkin co:SH Orkin co:Miehelson Adra co:Adra co:M McBurney co:M McBurney Herman co:M McBurney Boer Adra Bender Barnard c o : M W Kilimann c o : M W Kilimann c o : M W Kilimann Hudson Moriguchi Ikenaka Timsit Milner co:RJ Milner co:RJ Milner co'JA Todd co:JA Todd co:A Dautigny Nave Nave Frankel Frankel Frankel Frankel Adler Zinn Zinn co:SDM Brown co:SDM Brown Nathans co:J Nathans co:J Nathans co: J Nathans Herman co:J Nathans

Refe~mcee

Nature 1981; 28~.253 Genetics 1990; 125:431 Genetics 1990; 125:431 Mouse News Lett 1984; 71:46 Nucl Acid Res 1988; 16:1642 J Biol Chem 1984; 259:.7941 Mol Endocrinol 1989; 3:1243 ref:Siracusa, Genetics 1991; 127:169 Science 1987; 237:415 J Biol Chem 1986; 261:7588 ref:Mullins, Mol Cell Biol 1987; 7:3916 ref:Mullins, Genomics 1988; 3:187 ref:Herman, Genornics 1990; 7:307 ref:Herman, Genomics 1991; 9:670 ref:Herman, Genomics 1991; 10:961 ref:Kay, Genomics 1991; 11:651 ref:Amar, Genomics 1988; 2:220 Science 1987; 237:415 PNAS 1984; 81:7412 BBRC 1987; 146:1064 PNAS 1989; 86:4142 Genomics 1991; 10:313 Cytogenet Cell C,enet 1989, 51.<370 Somatic Cell Mol Genet 1990; 16:487 Genet Res Camb 1990; 56:153 Genet Rcs Camb 1990; 56:153 Nature 1988; 335:82 Gene 1986; 45:275 Genomics 1988; 3:337 ref:Hamvas, Mamm Genome 1991; 2:72 Exp Cell Res 1990; 186:273 PNAS 1983; 80:472 refi SOm Cell Mel Genet 1988; 14:69 refiBrockderff, Genomics 1991; 10:17 refiRyder-Cook, EMBO J 1988; 7:3017 refiKay, Genomics 1991; 11:651 refiAdra, SOm Cell Mol Genet 1988; 14:69 Somatic Cell Mol Genet 1988; 14:69 refiDisteche, Genomics 1989; 5:177 ref:Cattanach, Cytogenet Cell Gen 1991; 56:137 refiHerman, Genomics 1990; 7:307 Genomics 1991; 9:670 refiAmar, Genomics 1988; 2:220 Biochem Genet 1990; 28:299 Somatic Cell Mol Genet 1988; 14:69 PNAS 1989; 86:9996 Cytogenet Cell Genet 1990;, 53:91 refiBrockdorff, Genomics 1991; 10:17 ref:Zander, PNAS 1988; 85:2929 refiCattanach, Cytogenet Cell Gen 1991; 56:137 PNAS 1987; 84:1454 Gene 1987; 55:333 J Mol Biol 1988; 199:587 J Neut~hem 1992; 58:1172 Cell 1985; 42:931 ref.'Chapman, Genomics 1991; 10:23 refiDerry, Genomics 1991; 10:593 refiHearne, Mamin Genome 1991; 1:273 refiMontagutelli, Mamm Genome 1991; 1:255 Nature 1986; 321:867 PNAS 1986; 83:9264. PNAS 1986; 83:9264 J Virol 1989; 63:3810 Mamm Genome 1992; 2:110 J Virol 1989; 53:3810 Mamm Genome 1992; 2:110 Genomics 1991; 9:642 Genomics 1991; 11:1097 Genomics 1991; 11:1097 ref:Hamvas, Genomics 1992; 12:363 ref:Hamvas, Genomics 1992; 12:363 Science 1986; 232:193 ref:Mu]lins, Genomics 1988; 3:187 ref:Herman, Genomics 1990; 7:307 ref:Ryder-Cook, EMBO J 1988; 7:3017 Genomics 1991; 9:670 tel:Faust, Genomics 1991; 11:154 Continued on next p a g e

415

J.T. Eppig: Clones and Probes Table 3. Continued. Chr S y n ~ a

X X X

Sbx spf Syn-1

~

Name

Sxr b X-homolog, (see Ube-1) sparse fur, (see Otc) synapsin I

Pr~e b

RFLVc Contactd

[R] pSE2

+ +

5E2 + x

Syp

X X X

"Tfe3" Tfm Timp

synaptophysin transcription factor E3 testicular feminization, (see Ar) tissue inhibitor of metalloproteinase

[HI GH183-1 mTFE3, probe 1, probe 2 unnamed + pMIF3/10 XG3/10C-21b, pG3/10-H4.3 1)3/10 (=pG3/10-H4.3) + pTIMP-8 pCR5 + pE2.2, AISgE2.2

co:deGennaro co:deGennaro Yang-Feng Kilimann co: deGennaro Ozcelik co:K Calame

Jackson Skup Gewert co:Williams Coulombe X Ube-1 ubiquitin-1 Mitchell Zacksenhaus Zacksenhaus Als9X eDNA + co:S Rastan X )fist inactive X specific transcript )fist eDNA + Brockdorff [H] 14A + co:A Ballabio MR20 + co:A Ballabio X Xlr X-linked family of B cell surface antigens pX310, pM1 + co:Cohen X X]r-1 X-linked B cell surface antigen-1 pMl + co:M Davis + Garchon X X]r-2 X-linked B cell surface antigen-2 pMl + co:M Davis + Garchon X "Xlr-rs" Xlr related sequences clones 9.10,17.4,9.7,3.14,1.37 Garchon X Zfx X-linked zinc finger protein mYfin Nagamine pDP1068 Page + co:Page [H] pCMPXY1 + Mitchell + Cattanach pDPII93 Mardon pDP1007 + co:D Page BSXB2 + co:R Levell-Badge [H] pMF-1 + co:P Goodfellow Zfx-RT/PCR + co:C Disteche X&Y "7" unnamed pYS0/B, p Y 3 7 1 / B , Avner,Bishop + Avner pY302/B Avner, Bishop + Avner X&Y Mov-15 pMov-15/1 + Harbers HpX co:R Jaenisch p15-4 Harbers X&Y Sxr sex reversal pYCRS/B + Nagamine pY291/B + Roberts pSxl Roberts Y "B3 locus" B3 locus: contig in Sxr region ~Zf.B.3, cT5.2.11 Mitchell Y Bkm-1 banded krait minor satellite DNA-1 pCS316 Nagamine 2[8] + Singh Y "D Y?" Y chr repeat (adjacent to Bkm sequence) ACll + Nishioka + Nishioka + Biddle Y "D Y ?" Y sequences ACC1,ACClfl + Nishioka Y "DY?" male sequence ACC2, ACC3 Nishioka Y "DY?" Y sequences 145SC5 + Nishioka Y "DY?" Y c h r sequence pY1, pY2, pY3 + co:Lamar pY2 + co:P Soriane Y "DY?" Y chr sequence ~.Y6flY45 Eicher Y "DY?" Y chr sequence pY353/B + Bishop + Boursot co:C Bishop co:C Bishop pYREP19(pY353/B subclone) Bradbury Y "DY?" Y chr sequence pYMT2/B Bishop Y "DY?" Y chr sequence [H] 12f, [H) 12f3 Leroy Y "DY?" Y repetitivesequence M34 + Singh Y Hya histocompatibility-Y pYS/B + Roberts Y Mtv-31 m a m m a r y tumor virus locus-31 MMTV8-21,MMTV8-29 + co:JE Majors Y Mtv-42 m a m m a r y tumor virus locus-42 MMTV LTR Nishikawa Y Murvy murine repeated virus, Y-linked pMuRVY-LTR + Eicher Hutchison Y Pmv-34 polytropic murine leukemia virus-34 JS-5 + Frankel Y Sby Sxrb Y-homolog (see Ube-2)

p~fez~e

ref:Avner, Trends in Genetics 1988; 4:18 ref:Amar, Genomies 1988; 2:220 PNAS 1986; 63:5679 EMBO J 1985; 4:1997 Mullins, Genomics 1990; 7:19 Am J Hum Genet 1990; 47:561 ref:Roman, MolCell Biol 1992; 12:817 Nucl Acid Res 1987; 15:4357 Nucl Acid Res 1982; 10:3069 EMBOJ 1987; 6:651 ref:Mullins, Genomics 1988; 3:187 J Biol Chern 1988; 263:1439 Nature 1991; 354:483 Somatic Cell MoI Genet 1989; 15:545 Cytogenet Cell C,enet 1990;, 53:20 refiKay, Nature 1991; 354:486 Nature 1991; 351:6322 ref:Borsani, Nature 1991; 351:325 ref:Borsani, Nature 1991~ 351:325 Nature 1985; 314:369 ref:Mullins, Genomics 1990; 7:19 Nucl Acid Res 1989; 17:9871 ref:Mullins, Genemics 1990; 7:19 Nucl Acid ires 1989; 17:9871 Nucl Acid Res 1989; 17:9871 Science 1989; 243:80 Genomics 1990; 7:37 ref:Keer, Genomics 1990; 7:566 Genetics 1989; 121:803 Cytogenet Cell Genet 1991; 56:137 Mol Cell Biol 1990; 10:681 ref:Barnard, Cytogenet Cell Genet 1990; 53:91 ref:Brockdorff, Genomics 1991; 10:17 ref:Herman, Genomics 1991; 10:96t ref:Adler, PNAS 1991; 88:4592 Mouse News Letter 1986; 74:98 Development 1987; 101 Supphl07-116 Mouse News Letter 1986; 74.@8 Development 1987; 101 Supphl07-116 Nature 1966; 324:682 ref'Jahner, Molec Cell Biel 1985; 5:2212 Cytogenet Cell Genet 1990;, 53:129 Nucl Acid Res 1987; 15:9227 PNAS 1988; 85.-6446 PNAS 1988; 85:6646 Genomics 1992; 12:28 Nucl Acid Res 1987; 15:9227 Mol C-en Genet 1988; 212:440 Genetics 1986; 113:417 Cytogenet Cell Genet 1989;, 50:195 Genome 1991; 34.@6 Genet Res, Camb 1988; 52:145 Genome 1987; 29:380 Teratology 1988; 38:181 Cell 1984; 37:171 ref:Herman, Genomics 1990; 7:307 Genetics 1989; 122:181 Nature 1985; 315:70 Heredity 1989; 63:289 refiBradbury, PNAS 1990; 87:4053 ref:Boyle, Genemics 1992; 12:108 PNAS 1990; 87:4053 Nucl Acid Res 1987; 15:2959 Development 1987; 101 (Supp):177 Mol Gen Genet 1988; 212:440 PNAS 1988; 85:6446 ref:Prochazlm, Mouse Genome 1990; 87:111 Lab Animal 1991; 25:4 Genetics 1989; 122:181 J Virel 1989; 63:4043 J Virol 1989; 63:3810

Continued on next page

J.T. Eppig: Clones and Probes

416 Table 3. Continued. Chr Syn-t~a

Y Y Y Y Y

Lcx~ Name

Probeb

RFLVc Contactd

Sby-1 Sby-2 Sry

ts A1S9 defective DNA replication gene (see Ube-2) ts A1S9 defective DNA replication gone (see Ube-3) sex-determining region of Chr Y L7.4.1, p422.04, p4.2.2 p.4.2.2 if41, p422.04 "Sxl locus" Sxl locus: contig in Sxr region cSx.2.6, cSx.l.1, cSx.l.10, cSx.l.3, cSx.2.7, cSx.D.1 "T5 locus" T5 locus: contig in Sxr region ~.T5.G.9, ~.T5.G.7, cT5.2.13 cT5.2.16, cT5.2.12

Y Y Y

Tdy "Tg2736" Ube-2

testis-determining-Y transgene of Y B R strain Amy-l.1 ubiquitin-2

Y Y Y

Ube-3 "Xlrl" Xmv-7

ubiquitin-3 X]r-likesequences xenotropicmurine leukemia virus-7

Y

Xmv-11

xenotropicmurine leukemia virus-ll

Y

Xmv-40

xenotropic murine leukemia virus-40

Y

YB10

Y-specific B10 derived sequences

Y

"Zf2 locus" Zf2 locus: contig in Sxr region

Y

Zfy-1

Y-linked zinc finger protein-1

Y

Zfy-2

(from SJL/J mice) (from 129 mice) Y-linked zinc finger protein-2

?

Ace

angiotensin-eonverting enzyme

? ?

Ache Acre

(testis form) (testis form) (testis form) acetylcholinesterase acetylcholine receptor s

? ?

"Acs" Actg-psl

acyl-CoA synthetase T-actin pseudogene-1

? ?

Actg-ps2 Actvs

T-actin pseudogene-2 actin, vascular smooth muscle a

? ? ? ? ?

Acvr" Acvr2b Acvba Acvbb Adss

activin receptor aetivin receptor IIB aetivin ~A activin ]3B adenylesuccinate synthetase

pYS/B + probeS poMJ3 + Als9X c D N A + Als9X c D N A + Xlr genomic subclones + JS-6+JS-10 + + JS-6+JS-10 + +

JS-6+JS-10

+ +

Gubbay Koopman co:R Lovell-Badge Mitchell Mitchell Mitchell Mitchell Roberts Jones Mitchell co:S Rastan co:S Rastan Garchon Frankel Frankel Frankel Frankel

Frankel Frankel pYB10 co:EM Eicher + Tucker + Eicher ~.Zf.F.8, kZfiF.2, Mitchell cZf.l.8, cZf.2.1 Mitchell mYfin + Nagamine pDP1068 Page [HI pCMPXY1 + Mitchell pDP1171 Page + Mardon pDP1055 + Mardon Zfy-1 cDNA Ashworth Probes 1,2,3 (fr Zfy-1 eDNA) co:A Ashworth cesmids cEMS132, cEMS189 Simpson cesmids cEMS143, cEMS128 Simpson pGZfylD + Kalikin c21 Gubbay mYfin + Nagamine pDP1068 Page [H] pCMPXY1 + Mitchell pDPll71 Page Mardon pDP1055, pDPl122 Mardon pEMS283, probe A Simpson pEMS612, probe B Simpson pEMS616 Simpson probe C (pEMS616) + Simpson pEMS602.2, probe D Simpson pDP1350, probe E Simpson cosmids eEMS212, eEMS206 Simpson cosmids cEMS142, cEMS129 Simpson cosmids cEMS134, cEMS131 Simpson ccsmids cEMS136, eEMS137 Simpson cesmids cEMS138, cEMS127 Simpson ccsmids cEMS139 Simpson ACE.31, ACE.11 Bernstein G21-5.2 Shai rACE.l, rACE.7, rACE.13 Howard rACE.14, rACE.21, rACE.22 Howard tACE.31, rACE.33 Howard probes Ela, E1]3, E2, E3A Shelley kgs kge61, ~.gr Buonanno Acre eDNA Gardner clone 272 Weiner XmA81,~.mA36, Man %reAl 18,~.mA119 M an ~.mA14 Begg pMaVSM- 2 Mi n clones R1, $22 Min pSB 119-7,pSB 18a,pSB 12b Min clones pS0, p44, p7 Rhyner pmActR1, pmActR2 Mathews S1,N1,D1,M1,L1,Aetr2b PCR Attiaano [R] Acvba eDNA co:K Mayo [R] Acvbb eDNA co:K Mayo Adss eDNA co:BF Cooper

Refemlcee

Nature 1990, 346:245 Nature 1990;, 345:450 reflKoopman, Nature 1991; 351:117 Genomics 1992; 12:26 Genomics 1992; 12:26 Genomics 1992; 12:26 Genomics 1992; 12:26 PNAS 1988; 85.~446 Nucl Acid Res 1989; 17:6613 Nature 1991; 354:483 refiKay, Nature 1991; 354:486 refiKay, Nature 1991; 354:486 Nucl Acid Res 1989; 17:9871 J Virol 1989; 63:1763 M a m m Genome 1992; 2:110 J Virel 1989; 63:1763 M a m m Genome 1992; 2:110 J Virel 1989; 63:1763 M a m m Genome 1992; 2:110 ref:Prepst, Oncogene Rcs 1988; 2:227 Genetics 1989; 122:169 Genetics 1989; 122:181 Genomics 1992; 12:26 Genomics 1992; 12:26 Science 1989; 243:80 Genomics 1990; 7:37 Genetics 1989; 121:803 Cell 1987; 51:1091 Science 1989; 243:78 Science 1989; 243:78 Nucl Acid Res 1989; 17:2864 ref:Gubbay, Development 1990; 109:647 Genomics 1991; 11:601 Genomics 1991; 11:601 BBRC 1989;, 165:1286 Development 1990; 109:647 Science 1989; 243:80 Genomics 1990; 7:37 Genetics 1989; 121:803 Cell 1987; 51:1091 Science 1989; 243:78 Science 1989; 243:78 Genomics 1991; 11:601 Genomics 1991; 11:601 Genomics 1991; 11:601 personal communication, 1992 Genomics 1991; 11:601 Genomics 1991; 11:601 Genomics 1991; 11:601 Gonomics 1991; 11:601 Genomics 1991; 11:601 Genomics 1991; 11:601 Gonomics 1991; 11:601 Gonomics 1991; 11:601 J Biol Chem 1989; 264:11945 BBRC 1990; 167:1128 Mol Cell Biol 1990; 10:4294 Mol Cell Biol 1990; 10:4294 Mol Cell Biol 1990; 10:4294 J Biol Chem 1991; 266:23083 J Biol Chem 1989; 264:7611 Nuci Acid Res 1990; 18:6714 J Biol Chem 1991; 266:23525 Nucl Acid Res 1987; 15:3291 Nucl Acid Res 1987; 15:3291 J Mol Biol 1988; 203:677 N u d Acid Res 1988; 16:10374 J Biol Chem 1990; 265:16667 J Biol Chem 1990; 265:16667 J Neuresci Res 1990; 27:144 Cell 1991; 65:973 Cell 1992; 68.@7 ref: Manors, Mech Devel 1992; 36:141 ref: Manova, Mech Devel 1992; 36:141 refiGuicherit, J Biol Chem 1991; 266:22582 Continued on next p a g e

417

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Symbda

? ? ? ?

LocusName

P~2 b

Akp-psl Alkaline phosphatase pseudogene AKR-MuLV+ flank AKR-MuLV+flank AKV env probe

RFLVc C c n l ~

APW genomic done 623, done 614 done 621 pAKV-4

Manes

pAKV-3, -5 pEco

?

Aldo-1

aldolase-1, skeletal muscle, brain (alpha) u n n a m e d pAM, pAB, pAN2

?

Aldo-2

aldolase-2 (beta)

? ? ? ? ?

Amh-rs3 Amh-rs5 Amh-rs6 Amh-rs8 "Apex"

p ~ , pAB

Arbp Arep

JR] A4C9

plO, pll anti-Mullerian hormone related seq-3 [R] pRMIS1 anti-Mullerian hormone related seq-5 [R] pRMIS1 anti-Mullerian hormone related seq-6 [R] pRMIS1 anti-Mullerian hormone related seq-8 [R] pRMIS1 apurinic/apyrimidinic endonuclease, pExEl, pExE2 DNA3'-phosphatase, 3'-5'-exonuclease, DNA3' repair diesterase acidic ribosomal phosphoprotein PO Arbp cDNA androgen-regulated epididymal protein XM53, pM53

pMS~ Arg- 1 "Ast-l" "Ast-2" "Ast-3"

arginase-1 (liver) astroglial cell transcript-1 astreglial cell transcript-2 astroglial cell transcript-3

"Atf-4"

RctJv$~tln~ trAnR.~r~n~hn f ~ r t a r

M53 [R]pARGr-2

p4 p14 p57 A

n r l ~ m A rP!7.A

+ + + +

Lowy Lowy Bautch Herr Herr Mucenski Chattopadhyay Mestek Stauffer Colbert Simon Sala-Trepat Maine co:RL Care, Biogen co:RL Care, Biogen co:RL Cate, Biogen co:RL Cate, Biogen Seki Krowczynska Ghyselinck Ghyselinck Ghyselinck Ohtake Rhyner Rhyner Rhyner

l~'e~ncee

Genomics 1990; 8:541 PNAS 1960; 77:614 PNAS 1960; 77:614 J Virol 1986 60;,693 J Virol 1983 46:70 J Viral 1983 46:70 J Virol 1987; 61:2929 PNAS 1980; 77:5774 Nud Acid Res 1987; 15:10595 J Biol Chem 1990; 265:11773 Devel Biol 1992; 149:66 J Biol Chem 1983; 258:14576 PNAS 1985; 82:2442 BBA 1992; 1129:243 ref:King, Genomies 1991; 11:273 ref:King, Genomics 1991; 11:273 re~King, Genomics 1991; 11:273 ref:King, Genomics 1991; 11:273 J Biol Chem 1991; 266:20797 Nucl Acid Re~ 1989; 17:6408 J Mol Endocrinol 1990; 4:5

Nuc Acid Re~ 1990; 18:7144 J Reprod Felt 1991; 93:461 BBRC 1987; 146:1064 J N e u r e ~ Res 1990; 27:144 J Ne~ Res 1990; 27:144 J Neuresei Res 1990; 27:144

J.T. Eppig: Clones and Probes

418 Table 3. Continued. Chr Symhta

?

"Ck-psl"

?

"Ck-ps2"

?

"Ck-ps3"

?

Clqa

?

Clqb

?

Clgi

?

t'~l~

LocusName

l~obeb

RFLVc C~ntactd

creatine kinase-pseudogene 1 ).-P1 + (may=Ck-1 or Ck-5) creatine kinase-pseudogene 2 k-P2 + (may=Ck-1 or Ck-5) creatine kinase-pseudogene 3 k-P3 + (may=Ck-1 or Ck-5) complement component 1, q subcomponent, A3, A10, A l l a polypeptide complement component 1, q subcomponent, pCl-q-B-C65, polypeptide pClq-B-C61, pClq-B-C301, pClq-B-C56, pC11-B-C78 XB15, 7~B18 collagenase inhibitor 16C8 o.mnlom~n+ lvo~a ~nh{h{~v rR1 ~PRPM.~

l~f~~mcee

co:B Wieringa

refivanDeursen, Genomics 1992; 12:340

co:B Wieringa

refivanDeursen, Genomics 1992; 12:340

co:B Wieringa

refivanDeursen, Genomics 1992; 12:340

co:M Loos

ref.'Petry, J Immunol 1991; 147:3988

Wood Wood Wood Perry Edwards en:MP Tennlswond

Immunol Lett 1988; 17:59 Immunol Lett 1988; 17:59 Immuno] Lett 1988; 17:59 FEBS Lett 1989;, 258:89 Nucl Acid Res 1986; 14:8863 ref.'l~er. BBRC 1987:147:196

419

J.T. Eppig: Clones and Probes Table 3. Continued. Chr S y m ~ a

? ? ?

DONds35 DONds36 DONds37 DOTu6

Iz~us Name

Probeb

RFLVe C~at~td

DNA segment, Nuffield Dept of Surgery-35 MUSTYR (micresat) + co2A Todd DNA segment, Nuffield Dept of Surgery-36 MUSEIF4AL (microsat) + co:JA Todd + co'~IA Todd DNA segment, Nuffield Dept of Surgery-37 MUSTYR (microsat) ? DNA segment, Tubingen-6 cos5-41 Vincek Sertic DOTu7 DNA segment, Tubingen-7 cos4-3-3 + Vincek Sertic DOTu8 DNA segment, Tubingen-8 cos6-2-4 + Vincek Settle DOTull DNA segment, Tubingen-ll cos3-6-1 Vincek Sertic DOTu12 DNA segment, Tubingen-12 cos9-118 Vincek Sertic DOTu13 DNA segment, Tubingen-13 cos1-115 Vineek Sertie DOTul5 DNA segment, Tubingen-15 coal-5 Vincek " Sertic DOTu17 DNA segment, Tubingen-17 k41 Vincek Sertic DOTu31 DNA segment, Tubingen-31 ).107 Vincek Sertic DOTu44 DNA segment, Tubingen-44 E21 Vineek Sertic DOTu46 DNA segment, Tubingen-46 X310 Vincek Sertic DOTu51 DNA segment, Tubingen-51 k297 + Vincek + co:J Klein Sertic Dbi diazepam binding inhibitor ODN-1, DBI-7 Owen Dlx-2 distal-less homolog Dlx-2 cDNA co:KA Mahon Drd-2 dompamine D2A receptor Drd-2 genomic co:KL O'Malley "Ec 1" EC repeat pMR161, pMR272 Bennett "Ect" E. coli transaminase homology ECA39 Niwa "Edn 1" endothelin-1 Ednl eDNA Inoune Eef-2 eukaryotic translation elongation factor 2 cosmid cMEF2-10 Ishiura Eef2-psl eukaryotyic translation elongation cosmid eMER2-10 Koide factor-2 pseudogene 1 cosmids cMER1, eMER2, Koide Eel21 repetitive EeP2 like sequences cosmids cMER7, cMER9, Koide cosmids cMER52, cMER8 Koide probes BIM200,SS530,L2,R2 Koide Yamamoto ? "Eef2-rsl" gene expressed preferentially in MEL cells pMERx, pMERS, ~.ER5 "Eel2 related" ~.mTu- I, p W R l Roth ? Eifla eukaryotic translation initiation Ella-eDNA Lu factor l a (Tu) pMPe7, kME4, k M E I Stevenson ? Ela-2 elastase, typeII [R] R E L R A D + co:C Boyd ? Eln elastin clones p70ZN8, p7ZON6.1, Alpert ? "Embp3-rl"erythrecyte membrane protein band 3 p7OZN19.2, pMK2CX, Alpert related-1 pMKN, pMKA, pMTAL Alpert MM37 flank Haupt Emi-1 proviral insertion Emi-1 pBEgl, pBEg2, pBEg3 Lazar Eno-2 enolase-2 (7, neuron) Eno-2 eDNA Kaghad pBI~l Lamande Eno-3 enolase-3 ([3, muscle) 283bp Eno-3 eDNA Barbieri ~cDME vanDuin Ercc- 1 excisionrepair-1 clones 1B, 5A, 4A, 3.1 vanDuin [H] pE12-12 co:M vanDuin pM3L- 1,pM3L-2,p3L-3,pM3-1 Weeda ? Ercc-3 excision repair-3 Evx-2 genomic, Baatian ? Evx-2 even-skipped homeotic gene-2 homolog Evx-2 eDNA Bastian 10 or 15 Fabph-3 fatty acid binding protein, heart-3 [R] H-FABP eDNA Heuckeroth pFAS-1 Paulauskis ? Fas fatty acid synthase Fischman ? Fert fer (fms/fps related) protein kinase, testis spec [H] TES-53 Fischman Fert-cDNA co:Y Yarden fibroblast growth factor receptor-1 mflg-10 ? Fgfr- 1 co:LT Williams Fgfr- 1 eDNA co:B Sato Fgfr- 1 genomic co:LT Williams Fgfr-2 eDNA ? Fgfr-2 fibroblast growth factor receptor-2 Kornbluth bek eDNA co:AP M c M a h o n ~.PTL61, PTK-61 ? Fgfr-4 fibroblast growth factor receptor-4 Nelson ? "Fkbp" FKS06 binding protein MF6-4-2 Rothnagel pFM3-2, pFM6- IA2 7 Flg filaggrin Rothnagel cosmid cFM6.1A2 Fasel MB-1, MB-2, MB-3 co:R Lemischka fetal liver kinase-2 Flk-2 eDNA ? Flk-2

ref:Hearne, M a m m Genome 1991; 1:273 ref:Hearne, M a m m Genome 1991; 1:273 ref.'Hearne, M a m m Genome 1991; 1:273 Genomics 1989; 5:773 M a m m Genome 1992; 2:138 Genomics 1989; 5:773 M a m m Genome 1992; 2:138 Genomics 1989; 5:773 M a m m Genome 1992; 2:138 Genomics 1989; 5:773 M a m m Genome 1992; 2:138 Genornics 1989; 5:773 M a m m Genome 1992; 2:138 Genomics 1989i 5:773 M a m m Genome 1992; 2:138 Genomics 1989; 5:773 M a m m Genome 1992; 2:138 Genornics 1989; 5:773 M a m m Genome 1992; 2:138 Genomics 1989; 5:773 M a m m Genome 1992; 2:138 Genornics 1989; 5:773 M a m m Genome 1992; 2:138 Genomics 1989; 5:773 M a m m Genome 1992; 2:138 Genomies 1989; 5:773 ref:Moen, M a m m Genome 1991; 1:217 M a m m Genome 1992; 2:138 Mol Brain Res 1989; 6:101 ref:Robinson, New Biol 1991; 3:1183 ref:Mack, J Neurochem 1991; 57:795 Mol Cell Biol 1984; 4:1561 Nucl Acid Res 1990; 18:6709 PNAS 1989; 86"2863 Gene 1989; 85:427 Genomics 1990; 6:80 Genomics 1990; 6:80 Genomics 1990; 6:80 Genomics 1990; 6:80 Genomics 1990; 6:80 Gene 1989; 8~.337 Mol Cell Biol 1987; 7:3929 Nucl Acid Res 1989; 17:442 Nucl Acid Res 1986; 14:8307 ref.'Schurr,Genomics 1990; 8:477 J BiolChem 1988;263:17092 J BiolChem 1988; 263:17092 J BiolChem 1988;263:17092 Cell 1991;65:753 B B R C 1986; 141:271 Nucl Acid Res 1990; 18:3638 P N A S 1989;86:4445 Differentiation1990; 45:179 Nucl Acid Res 1988; 16:5305 Nucl Acid Res 1988; 16:5305 ref:Saunders, Genomics 1990; 8:525 Carcinogenesis 1991; 12:2361 E M B O J 1990;9:1839 E M B O J 1990;9:1839 J BiolChem 1987; 262:9709 J Biol Chem 19~8; 263:7049 Mol Cell Biol 1990; 10:146 Mol Cell Biol 1990; 10:146 ref:Safran, Oncogene 1990; 5:635 ref.'Peters, Development 1992; 114:233 ref:Saito, BBRC 1992; 183:688 res Development 1992; 114:233 Mol Cell Biol 1988; 8:5541 ref:Stark, Development 1991; 113:641 Gene 1991; [email protected] J Biol Chem 1987; 262:15643 J Biol Chem 1990; 265:18~2 BBRC 1991; 178'~ ref:Matthews, Cell 1991; 65:1143 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

420 Table 3. Continued. Chr Symbola

Loc~s Name

? ? ? ? ? ? ? ? ? ?

Fnrb Folbp-1 Folbp-2 Ftll "Gl-genel" "Gl-gene2" "Gl-gene3" Glst Gabrb-2 Gabrd

fibronectin receptor, ~ (integrin) folate binding protein -1 folate binding protein -2 ferritin, light chain-1 unknown gene expressed in G1, #1 unknown gene expressed in G1, #2 unknown gene expressed in G1, #3 Gl-to-S transition GTP-binding protein GABA-A receptor, subunit beta-2 GABA-A receptor, subunit delta

? ?

Galbp Gapd-ps

?

? ? ?

Gas-5 "Gbp-2" Gfrp "Ggtb-i"

?

Ggtp

~ galactoaidase binding protein glyceraldehyde-3-phosphate dehydrogenase pseudogene growth arrest specific gene-5 guanylate nucleotide binding protein-2 growth factor response protein cloned gene, influences Ggtb activity y-glutamyl transpeptidase

? ?

Ghrf "Gir"

growth hormone releasing factor glucocorticoid induced receptor

?

Gja-3

?

Gja-4

?

Glur- 7

?

"Gmem"

?

Gnai

?

Gnai-1

?

Gnai-3

? ? ? ? ? ? ?

Gnaz Gna0 "Gnal0" "Gnall" "Gnal2" "Gna13" "Gna14"

Probeb

RFLVc Contactd

l~fe~mcee

clone 55, clone ST1 pKD18 pKD21 pMLF16, pMLF27 LG-5 eDNA LG-61 eDNA LG-74 eDNA [H] pGH5 LMCIIG2,6-1 mGASI-dash mGASIII-dash mGAS-VI fix 1/21 Gapd 1.9 kb

Tominaga co:ID Goldman co:ID Goldman Beaumont co:AB Pardee co:AB Pardee co:AB Pardee Hoshino co:DR B u t t Sommer Sommer Sommer Poirier Galland

FEBS Lett 1988; 238:315 refiBrigle, J Biol Chem 1991; 266:17243 refiBrigle, J Biol Chem 1991; 266:17243 J Biol Chem 1989; 264:7498 ref:Nikaide, Exp Cell Res 1991; 192:102 ref:Nikaido, Exp Cell Res 1991; 192:102 ref:Nikaido, Exp Cell Res 1991; 192:102 EMBO J 1989; 8:3807 ref:Wang, Brain Res Bull 1991; 27:731 DNA & Cell Biol 1990; 9:561 DNA & Cell Biol 1990; 9:561 DNA & Cell Biol 1990; 9:561 Development 1991; 113:1105 Biochimie 1990; 72:759

Gas-5 eDNA- 1 mag-2 eDNA nut/77 (=done 3CH77) GTcDNA-2 [R] Ggt eDNA

Schneider co:DM Paulnock Hazel Lopez Coloma co:D Beer, H Pitot Suhr Harrigan H arriga n co:DL Paul

Cell 1988; 54:787 ref:Wynn, J Immunol 1991; 147:4384 PNAS 1988; 85:8444 BBRC 1988; 156:1223 Nucl Acid Res 1986; 14:1393 ref:Gattone II, Devel Biol 1990; 138:225 Mol Endoerinol 1989; 3:1693 Mol Endocrinol 1991; 5:1331 Mol Endocrinol 1991; 5:1331 ref:Shiels, Biochem Biophys Acts 1991; 1097:81

Willecke Willecke Sakimura Sakimura Sakimura Weller Weller Weller Sullivan

J Cell Bid 1991; 114:1049 J Cell Biol 1991; 114:1049 Neuron 1992; 8:267 Neuron 1992; 8:267 Neuron 1992; 8:267 J Cell Biol 1991; 112:355 J Cell Biol 1991; 112:355 J Cell Biol 1991; 112:355 PNAS 1986; 83:6687

"Gnal5" "Gnrhp" "Gp42" Gp70 Gpcr Gpx

mGHRH clones 4.2, 7.3, RP39, RP105, RP82 gap junction membrane channel protein a3 MP70 (connexin 46) gap junction membrane channel protein a4 Cx37 eDNA, (connexin 37) Cx37 genomic glutamate receptor 7 (y2) ;g3K16-1, pG16-11 pG16-2, pG16-3, pG16-1 pG16-26, pSPGRy2 glial mesenchymal extracellular matrix M20/1, R14/2, Mog, Mo2/2, glycoprotein S15, r5'-14, r5'-18, 1"5'-19, r5'-6, 03'-23, 03'-22, o3'-26 guanine nudeotide binding protein, Gin eDNA a inhibiting (-1?, -2?, -3?) guanine nucleotide binding protein, [R] Gnai-1 cDNA a inhibiting-1 guanine nudeotide binding protein, [R] Gnai-3 eDNA a inhibiting-3 guanine nucleotide binding protein az Gnaz PCR-cDNA guanine nudeotide binding protein a0 Gna0 PCR-cDNA guanine nudeotide binding protein a l 0 G n a l 0 PeR-eDNA guanine nudeotide binding protein a l 1 G n a l l PCR-cDNA guanine nucleotide binding protein a12 G n a l 2 PeR-eDNA guanine nudeotide binding protein a13 Gnal3 PCR-cDNA guanine nucleotide binding protein a14 G n a l 4 PCR-cDNA Gna14 eDNA guanine nudeotide binding protein a15 G n a l 5 eDNA GnRH associated protein kmGP- 1, ~.mGP-2 glycoprotein 42 (Ig superfamily member) X66, ~23 glycoprotein 70 clone 26 G-protoin coupled receptor clone 4.2 glutathione perexJdase GSH-Px c D N A

Grp78

glucose-regulated protein 78 kDa

"Grp94"

glucose-regulated protein 94 kDa

"Grpr" Gsh-5 Cetb-1

gastrin releasing peptide receptor genornic screened homeobox-5 glutathione S-transferase Ybl subunit

Gs~-2 Ce~-4 "Gstc-2" G~a

glutathione S-transferase Yb2 subunit glutathione S-transferase Yb4 subunit glutathione S-transferase Yc2 subunit glycophorin A, erythroid specific

"Ha-A10"

hemopeietic cell antigen l14/A10

"Hist4?"

H4 histone

"Hist3?"

H3 histone

Jones Blatt Jones Blatt Strathmann Strathmann Strathmann Strathmann Strathmann Strathmann Stratbmann co:MI Simon co:MI Simon Mason Altruda Baughman Baughman Chambers EI-Hage [CI-I]p3C5 Tin g Day [R] pR78(-195,-88) Day clone 42-9 Parfett [CH] p4A3 Lee Kim MBRI, MBR2 Spindel done 60h Singh pmGT10 Townsend pGTS.75 Pearson [R] pGTA/C44 Ding pmGT2 Townsend pGT55 Pearson done 6.1 co:DL Eaton XGP3, pGP315 Matsui pGX7, Gypa-PCR co:DJ Wilson CDM8.A10.1, CDM8.A10.2, Dougherty CDM8.A10.3 Dougherty done 12, done 53 Meier [H] pF0103A, [H] H4F2 Seldin [D]H3 Lifton Johnson

J Biol Chem 1987; 262:14241 PNAS 1988; 85:7642 J Biol Chem 1987; 262:14241 PNAS 1988; 85:7642 PNAS 1989; 86:7407 PNAS 1989; 86:7407 PNAS 1989; 86:7407 PNAS 1989; 86:7407 PNAS 1989; 86:7407 PNAS 1989; 86:7407 PNAS 1989; 86:7407 ref:Wilkie, PNAS 1991; 88:10049 ref:Wilkie, PNAS 1991; 88:10049 Science 1986; 234:1366 Gene 1989; 85:445 Mol Endocrinol 1991; 5:637 Mol Endocrinol 1991; 5:637 EMBO J 1986; 5:1221 Devel Genet 1990; 11:149 Gene 1987; 55:147 DNA 1989; 8:301 DNA 1989; 8:301 Gene 1989; 82:291 J Biol Chem 1983; 258:597 Differentiation 1990; 42:153 Molec Endoerinol 1990; 4:1956 PNAS 1991; 88:10706 J Biol Chem 1989; 264:21582 J Biol Chem 1988; 263:13324 J Biol Chem 1985; 260:13268 J Biol Chem 1989; 264:21582 J Biol Chem 1988; 263:13324 ref:TM Buetler, Canc Res 1992; 52:314 Gene 1989; 77:325 ref:Gu, Bioch Biopbys Res Corn 1991; 177:202 J Biol Chem 1989; 264:6509 J Biol Chem 1989; 264:6509 Nucl Acid Res 1989; 17:795 Nucl Acid Res 1987; 15:5900 CSH Sympos Quant Biol 1977; 42:1047 Exp Cell Res 1990; 187:69 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

421

Table 3. Continued. Chr Symbola

Locus Name

Probeb

RFLW Contactd

[H] H3F2, pF0422 MM531 MH143 kMH2 LMH4 kMH6, kMH8 LMH10 H2A.X cDNA MH611,MH321,MH921 milL8-2 [HI HMG-17 eDNA

?

"Hist?"

H1 histone

? ? ? ? ? ? ? ?

"Hist?" "Hist?" "Hist?" "Hist?" "Hist2A.X" Histl-3.3ps "Hl-l" Hmgl7

H2A, H2B, H3 histone H2A, H2B H2A, H2B, H4 histene H2A histone histone 2A.X H3.3-1ike pseudogene hepatic triacylglycerol lipase high mobility group protein-17

?

"Hmgi-c"

? ? ? 9 or

Hox-8.1 Hox-9 "Hcph" 11 Hpl

? ? ? ? ?

"Hsa" "Hsc70t" "Hsfl" "Hsf2" Hsp60 Hsp70-2

?

Hsp70-ps

pM17c HGMI-Cll, HMGI-C7, HMGI-C4 homeo box-8 cluster, msh like rash2 PCR clones homeo box-9 cluster, rash like rrmh3 PCR clones heatopceitic cell phosphatase PTPty42 hepatic lipase Hpl eDNA Hpl eDNA- 1 heat-stable antigen X62 heat shock protein 70 kDa cognate gene, testes HS2, GE6 heat shock factor 1 C12 heat shock factor 2 C9 heat shock protein 60 kDa Hsp6O eDNA heat shock protein 70 kDa-2 Z621, pM3.8 eDNA 6.5, eDNA 5.3 heat shock protein 70 kDa pseudogene L4, pMHS213

? ? ?

Hsp86-ps Hap89 I-Isp90

heat shock protein, 86kDa-pseudogene Hsp86-ps genomic heat shock protein 89 kDa pC6-23 heat shock protein 90 kDa (glucose-regulated) GRP94

? ? ?

"Ido" Ifil0 I12r

indoleamine 2,3-dioxygenase interferon activated gene-10 (IP-10) interleukin-2 receptor

?

I13rb

interleukin-3 receptor, 13 chain

?

high mobility group protein I-C

pBS25, p13S27 C7 eDNA pmIL-2R-1, pmIL2R-2, prnIL-2R-3 pmIL2Rprl AIC2-2, AICR-26 AIC2A eDNA AIC2B eDNA

?

I15ra

? ?

"I15rb" I16r

?

I17r

? ? ?

I1-10 "Impd" "Ina"

? ? ?

"Inreabp" "Intg" Ip3r

?

Ipp

? ? ? ?

Irebp Irf- 1 "Itgb4" Kcal-1

? ? ?

Kcal-2 Kcal-3 Kca2-1

Seldin Seiler-Tuyns Graves Rasheed Rasheed Rasheed Rasheed co:T Morita Wellman Oka Landsman Johnson Landsman Manfioletti Manfioletti Holland Holland co:JN Ihle Kirchgeasner Chang co:PJ Nielsen Matsumoto co:I Morimoto co:I Merimoto Venner Zakeri Rosario Lowe Zakeri Moore Levine Mazzarella co:Green Habara-Ohkubo Ohmori Shimuzu Shimuzu co: R Germain Miyajima co:A Miyajima co:A Miyajima co:A Miyajima co:A Miyajima co:A Miyajima Devea Takaki Takaki Devea

I15rb eDNA pIL-SR.13, pIL-5R.2, pIL-SR.39, plL-5R.8 cl-24, cl-26, I15ra eDNA interleuldn-5 receptor, 13 chain (withdrawn, see Il3rb intorleukin-6 receptor 7~mIL6R/1, 7~mIL6R/2, co:G Ciliberto pCDmIL6R co:G Ciliberte interleukin-7 receptor clone M1, cloneM 2 Goodwin clones 1-1,22-1,7-3,7-2 co:SF Ziegler interleukin-10 cloneFl15 Moore inosinic acid dehycrogenase Impd e D N A co:J Smith a-internexin neruonal intermediate kaG-l, kaG-2 co:RKH Liem filament protein insulin response element A binding protien a4 Nasrin integrase I]-34 Kedar inositol triphosphate binding protein, P400 P-400 eDNA Furuichi clones 23-15, 23-5, 23-12S, Furuichi clones 5T1, 3T5, 6T4, 10TS, Furuichi clones 7T15,2C2,1C5,23-9,23-2 Fumichi mouse IAP promoted placental gene MIPPd4 co:RCC H u a n g co:RCC Huang iron-reaponsive element binding protein IRE-BP e D N A co:RD Klausner interferon regulatory factor-1 pMIRS co:T Taniguchi integrin ~4 16Ab34 Kennel K+ channel, A current, subtype 1, gene 1 MBK1.6, MBKI.18, Tempel (brain; homolog Dros. S h a k ) MBK1.9, MBK1.14 Tempel mShak Wei KC250 genomic Chandy Kvl.1 co:B Tempel K+ channel, A current, subtype 1, gene 2 KC238/255 genomic Chandy K+ channel, A current, subtype 1, gene 3 KC237 genornic Chandy K+ channel, A current, subtype 2, gene 1 mShal Wei interleukin-5 receptor alpha

Ref~e e

Nucl Acid Res 1987; 15:5900 J Mol Biol 1981; 151:607 J Mol Biol 1985; 183:179 Biochem Biophys Acta 1990; 1048:110 Biochem Biophys Acta 1990; 1048:110 Biochem Biophys Acta 1990; 1048:110 Biochem Biophys Acta 1990; 1048:110 ref:Nagata, Nucl Acid Res 1991; 19:2441 Gene 1987; 5~.29 Biochem Biophys Acta 1991; 1089:13 J Biol Chem 1986; 261:7479 Exp Cell Res 1990; 187:69 N u d Acid Res 1988; 16:10386 Nucl Acid Rea 1991; 19:6793 Nncl Acid Res 1991; 19:6793 Gene 1991; 98:253 Gene 1991; 98:253 ref:Yi, Mol Cell Biol 1992; 12:836 J Biol Chem 1989; 264:1473 ref.-FEBS Lett 1991; 289:69 ref:Wenger, Eur J Immunol 1991; 21:1039 BBRC 1990; lf~:43 ref:Sarge, Genes & Dev 1991; 5:1902 ref:Sarge, Genes & Dev 1991; 5:1902 Biochim Biophys Acta 1990; 1087:336 Mol Cell Biol 1988; 8:2925 Devel Biol 1992; 150:1 PNAS 1984; 81:2317 Mol Cell Biol 1988; 8:2925 J Biol Chem 1989; 254:5343 Mol Cell Biol 1984; 4:2142 J Biol Chem 1987; 262:8875 ref:Shyamala, Mol Cell Biol 1989; 9:3567 Gene 1991; 105:221 BBRC 1990;, 168:1261 Nucl Acid Res 1985; 13:1505 Nucl Acid Rce 1985; 13:1505 ref:Meruelo, Immunogenetics 1987; 25:361 In:Mol Cell Biol of Cytokinea, 1990; pp149-154 ref:Kitamura, PNAS 1991; 88:5082 ref:Wang, J Biol Chem 1992; 267:979 ref:Kitamura,PNAS 1991;98:5082 ref:Gorman, P N A S 1990; 87:5459 ref:Wang, J BiolChem 1992; 267:979 E M B O J 1991;[email protected] E M B O J 1990;9:4367 E M B O J 1990;9:4367 E M B O J 1991;[email protected] ref:Fiorillo, Eur J Immunol 1992; 22:799 ref:Fiorillo, Eur J Immunol 1992; 22:799 Cell 1990; 60.@41 ref:Pleiman, Mol Cell Biol 1991; 11:3052 Science 1990; 248:1230 ref:Tiedeman, Gene 1991; 97:289 refiChing, J Biol Chem 1991; 266:19459 Nature 1991; 354:317 Nucl Acid Rce 1990; 18:4022 Nucl Acid Res 1989; 17:5385 Nature 1989; 342:32 Nature 1989; 342:32 Nattme 1989; 342:32 ref:Mold, BBRC 1991; 177:1062 ref:Chang-Yeh, Nucl Acid IRes 1991; 19:3667 refiPhilpott, Nucl Acid Rce 1991; 19:6333 refiBabu, J Immunol 1992; 148:1934 J Cell Science 1992; 101:145 Nature 1968; 332:837 Nature 1988; 332:837 Science 1990; 248:599 Science 1990; 247:973 ref:Ghanshani, Genomics 1992; 12:190 Science 1990; 247:973 Science 1990; 247:973 Science 1990; 248:599 Continued on next page

J.T. Eppig: Clones and Probes

422 Table 3. Continued. Cl~ Symbola

Ldh-lps

lactate dehydrogenase-l, chain A, pseudo

kM10, kM16

Ldh-lps2 Ldh-lps3 "Lga" Lhr "Lig-l" "Lig-2" Lmyc-2

lactate dehydrogenase-l, chain A, pseudo-2 lactate dehydregenase-l, chain A, pseudo-3 Lupus-Graves antigen lutenizing hormone receptor lipogenic induced gene-1 lipogenic induced gene-2 lung carcinoma myc-related oncogene-2 (might be on Chr 12) liver protein 56kDa (selinium binding) lymphocyte-specific pretein- 1 leukotriene A4 hydrolase lymphocyte antigen-40 lymphoctye antigen-51 (BP-1/6C3 glycopretein ) lymphocyte antigen-54 (CD3 complex)

kMll, kM12 k~I14 clone 44 mLhr eDNA p7.2 pS.1 pL-myc.2nd.exon + pML2.1 + SLP-56 eDNA pJJ32, Lap1 cI)NA ksp3L, pZBL2 MMAC1A (mieresat) + clones II1-6, 1-1, 1-31, 1-14

?

Kcr2-1

?

Kcr2 -3

?

Kcr2-1

? ? ? ?

"Kcr3" Krev-1 Lag Lamp-1 Lamp-2

"Lp56" Lsp-1 Lta4h Ly-40 Ly-51 Ly-54

? ? ? ? ?

? ? ? ? ?

? ? ? ? ? ? ? 7

RFLVc Contactd

Lamr

Kcrl-I

?

Probeb

(homolog Dres. Shal) K+ channel, delayed rectifier, subtype 1, gene 1 mShab (homolog Dros. Shab) mShabl K+ channel, delayed rectifier, subtype 2, gene 1 mShaw (homolog Dro. S h a w ) Kvl.1 K+ channel, delayed rectifier, subtype 3, gene 1 Kv3.3 (homolog Dro. S h a w ) K+ channel, delayed rectifier, subtype 2, gene 1 Kv3.4 (homolog Dro. Shaw) K+ channel, delayed rectifier-3 (epithelial) Kcr3 eDNA Kirsten sarcoma revertant-1 [H] pKrev-1 leukemia associated gene [H] plS-1, [H] p18-2 lysosomal membrane glycopretein-1 lpgl20 eDNA Lamp-1 eDNA lysosomal membrane glycoprotein-2 lpgll0 eDNA RI_~, RL7 laminin receptor Lamr eDNA

?

?

Locus Name

Ref~ce e

Tempel Tempel

ref:Pak, PNAS 1991; 88:4386 Science 1990; 248:599 refiPak, J Neuresci 1991; 11:869 Science 1990; 248:599 ref:Ghanshani, Genomics 1992; 12:190 ref:Ghanshani, Genomics 1992; 12:190

co:B Tempel

ref:Ghanshani, Genomics 1992; 12:190

Honore Kitayama Zhu Granger Chen Granger Cha Makrides Hunt Li Fukasawa Fukasawa Fukasawa Baughman Gudermann Paulauskis Paulauskis Campbell Campbell Bansal Jongutra Medina eo:JA Todd Wu

EMBO J 1991; 10:2805 Cell 1989; 56:77 J Biol Chem 1989; 264:14556 J Biol Chem 1990; 265:12036 J Biol Chem 1988; 263:8754 J Biol Chem 1990; 265:12636 J Biol Chem 1990; 265:5008 Nucl Acid Res 1988; 16:2349 Nucl Acid Res 1988; 16:5195 ref:Fukasawa, Mol Biol Evol 1986; 3:330 Genetics 1987; 115:177 Genetics 1987; 115:177 Genetics 1987; 115:177 Mol Endocrinol 1991; 5:637 J Biol Chem 1992; 267:4479 J Biol Chem 1988; 263:7049 J Biol Chem 1988; 263:7049 Oncogene Res 1989; 4:47 Oncogene Res 1989; 4:47 Carcinogenesis 1990; 11:2071 J Immunol 1988; 141:3999 BBRC 1991; 176:1516 ref:Hearne, M a m m Genome 1991; 1:273 PNAS 1990; 87:993

co:L Wei co:L Wei co:B co:B

Salkoff Salkoff

pZ176, m-mb-l-W-8 Sakaguchi cosmids: C2, C4, C5, C8 Kashiwamura " L y a m - l " lymphocyte adhesion molcule-1 pZS, pZ6, pZ2-5, pK64 Neuhaus Lzm-s M lysozyme, structural Lzm eDNA Cross coslgl, coslgll, coslgl4, ccelgl5 Cross Lzp-s P lysozyme, structural ccslgl, ceslgll, coslgl5 Cross Lzp-a e D N A (PCR) Cortopassi M6pr mannose 6-phosphate receptor clone 1, clone 2 co:WS Sly M6pr e D N A Koster " M a e - l a " macrophage antigen a chain (integrin) ~MM-I Sastre clones: 106, I18, 217 Pytela clones:202, 204, 308 Pytela Macs myristeylated alanine-rich C kinase substrate MM1, MM2, MM3 Seykora F52 co:K Kato "Mak" male germ cell-associated kinase clones T32, T15, T22 Matsushime Mana-2 alpha mannosidase-2 MII-8, MII-48 Moremen "Mashl" m a m m a l i a n achaete-scute homolog-1 MASH1 eDNA eo:DJ Anderson "Mash2" m a m m a l i a n achaete-scute homolog-2 MASH2 eDNA co:DJ Anderson "Mcp-l" mast cell protease-1 Mcp-1 genomic co:L Hellman mast cell protease-2 "Mcp-2" cDNA-2,cDNA-4,cDNA14 Serafin "Mcp-4" mast cell protease-4 pMMCP4.1, pMMCP4.2, Serafin pMMCP4.3, pMMCP4.4, Serafin pMMCP4.5, pMMCP4.6 Serafin kgDNA- 1, kgDNA-2 Serafin Mcp-4 eDNA co:L Hellman "Mcp-5" mast cell protease-1 Mcp-5 eDNA co:L Hellman "Mcp-6" mast cell protease-6 T2, T1, Mcp-6 genomic Reynolds "Mcpl" m a s t cell protease like kgDNA-2 Serafin "Mcs" mitochondrial capsule seleno-protein MCS-cDNA Kleene Mdk midkidney gene MK cDNA Kadomatsu Kadomatsu ExMK1, ExMK2, ExMK3 Matsubara HB-GAM/PTN Naito "Mel-18" melanoma nuclear protein Mel-18, pD2-7 co:M Taniguchi "Mes-l" mouse exprcesion sequence-1 pB1 Williams Met-1 methyltransferase-1, [DNA cytosine-5] R6,RS,R4,R5,Rg,R11,R12 Bestor MTase eDNA co:W Schaffner Mfg-1 multifinger (zinc) gene-1 mfgl Passananti Mfg-2 multifinger (zinc) gene-2 mfg2 Passananti Mfg-3 multifinger (zinc) geae-3 mfg3 Passananti "Mfgp-E8" milk fat globule protein-EGF factor 8 2.1kb eDNA Stubbs "Mga-ps" MgA-Yll~eudo kmA19 Leader

EMBO J 1988; 7:3457 J Immunol 1990; 145:337 J Cell Biol 1991; 115:1149 PNAS 1988; 65:6232 EMBO J 1990; 9:1283 EMBO J 1990; 9:1283 Nucl Acid Res 1990; 18:1911 ref:Ma, J Biol Chem 1991; 266:10589 Biol Chem Hoppe-Seyler 1991; 372:297 PNAS 1986; 83:5644 EMBO J 1988; 7:1371 EMBO J 1938; 7:1371 PNAS 1991; 88:2505 ref:Umekage, FEBS Lett 1991; 286:147 Mol Cell Biol 1990; 10:2261 J Cell Biol 1991; 115:1521 ref:Johnson, Development 1992; 114:75 ref:Johnaon, Development 1992; 114:75 ref:Huang, Eur J Immunol 1991; 21:1611 J Biol Chem 1990; 265:423 J Biol Chem 1991; 266:1934 J Biol Chem 1991; 266:1934 J Biol Chem 1991; 266:1934 J Biol Chem 1991; 256:1934 ref:Huang, E u r J Immunol 1991; 21:1611 ref:Huang, E u r J Immunol 1991; 21:1611 J Biol Chem 1991; 256:3847 J Bioi Chem 1991; 266:1934 Devel Biol 1990; 137:395 BBRC 1990, 151:1312 J Cell Biol 1990; 110:607 J Biol Chem 1990; 265:9441 BBRC 1992; 183:701 refiTagawa, J Biol Chem 1990; 265:20021 Mol Cell Biol 1986; 6:4558 J Mol Biol 1988; 203:971 ref:Czank, Gene 1991; 109:259 PNAS 1989; 86:9417 PNAS 1989; 86:9417 PNAS 1989; 86:9417 PNAS 1990; 87'~417 Gene 1985; 36:369 Continued on next page

J.T. Eppig: Clones and Probes

423

Table 3. Continued. Chr Symbia

? ? .7

? .7 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? .7 ?

? ? ?

? ? ? ? ? ? ? ? ? ? ? ? ?

Locus Name

Probeb

RFLVc C c n t ~

Mgmt O-6-methylguanine-DNA methyltransferase pSS601, pSS500 co:S Mitra "Mgp-2hc" membrane glyeoprotein-2, heavy chain M4F2HC-1A,M4F2HC-50 P a r m a c e k M4F2HC-27, M4F2HC-59 Parmacek "Mhfd" NAD-dependent methylenetetrahydrofolate M-I~MB1 through MB40 Belanger dehydrogenase-methenyltetrahydrofolate MGB-2, MGB-8, MGB-12, Belanger cyelohydrolase MGB-13, MGB-14, MGB-15 Belanger Mip2 macrophage inflammatory protein-2 MIP-2-20a Tekamp-Olson Mmv-21 MCF endogenous virus-21 MCF100 + Frankel Mok-2 Kruppel zinc finger protein-2 MOK-2 eDNA, Ernoult-Lange GllMOK-2, G12MOK-2 Ernoult-Lange Mor-2 malate dehydrogenase, cytosolic LmmcMDH-1 Setoyama LmmcMDH-2 Seteyama Mov-2 Moloney leukemia virus-2 pMov-2 Harbers Mov-3 Moloney leukemia virus-3 probe BB eo:K Harbers Mov-12 Moloney leukemia virus-12 pl2a, pl2b, Mov-12 genomic co:Harbers Mov-21 Moloney leukemia virus-21 p21a, p21b, Mov-21 genomic co:Harbers "Mp2" myelin protein P2 L25-1 co:G Tennekoon "Mpcp" mitochondrial PO 4 carrier protein clone 9 Baughman Mpmv-26 modified polytrepic murine leukemia virus-26 JS-4 Frankel Mpmv-31 modified polytrepic murine leukemia virus-31 JS-4 + Frankel "Mrs" middle repetitive sequence 1.73kb genomic clone Decoville "Ms-" Per-related (Drosophilia) minisatellites pSP64.2.5EI Georgea (see Ms loci under various chromosomes clone 115 Ishida and Ms-Vntr-1 under multiple chr) Sp34, Sp~, Sp6, Sp5 Nishimatsu Ms6-1 minisatellite 6-1 [H] probe 33.6 Jeffreys Ms6-3 minisatellite 6-3 [Hi probe 33.6 Jeffreys Ms15-2 minisatellite 15-2 [H] probes 33.15 Jeffreys Ms15-4 minisatellite 15-4 [H] probes 33.15 Jeffreys Ms15-8 minisatellite 15-8 [H] probes 33.15 Jeffreys "Ms a2" monocyte surface antigen-2 MS2-5, MS2-468, MS2-4 Yoshida MS2-54, MS2-12, MS2-8-1 Yoshida "Msbp-l" minisatellite specific DNA binding protien clone 1 Collick Mtap-2 microtubtfle-associated protein-2 Mtap-2 eDNA Wang "Mtap-2k" microtubule-associated pretein-2 kinase mMNK1 DeMiguel "Mthfd" NADP+ dependent methylenetetrahydrofolate [H] Mthfd eDNA Peri dehydregenase- cyclohydrol ase synthetase Mtv-4 m a m m a r y tumor virus locus-4 MTV env probe + Koizumi Mtv-46 m a m m a r y tumor virus locus-46 MMTV-env, MMTV-LTR + co:M Matsuyama MMTV-gag-pol + co:M M a t s u y a m a Mtv-47 m a m m a r y tumor virus locus-47 MMTV-env, MMTV-LTR +co:M M a t s u y a m a MMTV-gag-pol + co:M M a t s u y a m a m a m m a r y tumor virus locus-48 Mtv-48 MMTV-env, MMTV-LTR +co:M M a t s u y a m a MMTV-gag-pol +co:M M a t s u y a m a m a m m a r y tumor virus locus-49 Mtv-49 MMTV-env, MMTV-LTR +co:M M a t s u y a m a MMTV-gag-pol + co:M M a t s u y a m a Muc-I tumor-associated mucin 1 Muc-1 genomic Vos "Mvdp" major vas deferens protein ~ 4 , pUC-C61 Martinez clone 61 Pailhoux Myf5 myogenic factor 5 Myf5 genomie co:M Buckingham Myf5 genomic-1 eo:M Buckingham "Myf6" myogenic factor 6 Myf6 genomie Miner Nf-1 neurofibromateais type- 1 pmDV1 Viskochil pmDV1, 1.66kb PCR NF-1 co:NG Copeland "Nflbl" nuclear factor I, brain type 1 kNFI-B1, kNFI-B6, I noue kNFI-B7, kNFI-B8 Inoue "Nflb2" nuclear factor I, brain type 2 kNFI-B2, kNFI-B 12 Inoue "Nflb3" nuclear factor I, brain type 3 kNFI-B3 Inoue "Nflb4" nuclear factor I, brain type 4 MqFI-B4 Inoue "Nkx-2.3" homoleg of Drosophila NK-2 Nk-2.3 genomie Price "Nkx-2.4" homolog of Drosophila NK-2 Nk-2.4 genomie Price Nos-1 nitric oxide synthase-1 (macrephage) pMac-NOS co:JM C u n n i n g h a m Nos-2 nitric oxide synthase-2 (brain) [R] Brain-NOS eo:JM C u n n i n g h a m "Npc62" nuclear pore complex glycoprotein p62 M34 co:G Krohne Nras-ps2 neureblastoma ras pseudogene-2 Nras-ps2 genomic Chang Ntcp Na+/taurocholate cotransporting polypeptide [R] prLNaBa Hagenbuch Oias-1 2'-5' oligoadenylate synthetase-1 L3, ME-12 Cohen clone 25, clone 16 Yan L2, cII eo:BRG Williams Oias-2 2'-5' oligoadenylate synthetase-2 I~, ME-8, ME-5 Cohen L1, cII, cIIfA co:BRG Williams "Oias-3" 2'-5' oligoadenylate synthetase-3 clone 9-2 co:GC Sen "Oias-4" 2'-5' oligoadenylate synthetase-4 clone 3-9 eo:GC Sen Osf-1 osteoblast specific factor-1 7.mOSF-1 Tezuka "Otf-11" octamer binding protein -11 Oct-ll eDNA Goldsborough Oxt oxytoei n ).3.3.1, k4.1.1 Hara P4ha proline 4-hydroxylase, cL polypeptide [H] PA-49 Helaakoski

Ref~c~e e

refiShiota, Biochemistry 1992; 31:1897 Nucl Acid Re8 1989; 17:1915 Nucl Acid Res 1989; 17:1915 J Biol Chem 1989;, 264:4837 Gene 1991; 97:283 Gene 1991; 97:283 J Exp Med 1990;, 172.@11 M a m m Genome 1992; 2:110 Mol Cell Biol 1990; 10:418

Mol Cell Biol 1990; 10:418 J Mol Biol 1988; 202:355 J Mol Biol 1988; 202:355 Nucl Acid Res 1982; 10:2521 ref:Jalmer, Molec Cell Biol 1985; 5:2212 ref:Moealehner, J Virel 1990; 64:3056 ref:Moealehner, J Virol 1990; 64:3056 ref'~arayanan, J Neurochem 1991; 57:75 Mol Endocrinoi 1991; 5:637 Genetics 1990; 124:221 M a m m Genome 1992; 2:110 Eur J Biochem 1988; 174:679 Nucl Acid Res 1987; 15:7193 Nucl Acid Res 1988; 16:3581 Nucl Acid Res 1988; 16:11831 Nucl Acid Res 1987; 15:2823 Nucl Acid Res 1987; 15:2823 Nucl Acid IRes 1987; 15:2823 Nucl Acid Res 1987; 15:2823 Nucl Acid Res 1987; 15:2823 International Immunol 1990; 2:585 International Immunol 1990; 2:585 Nucl Acid Rss 1991; 19:6399 Nucl Acid Res 1988; 11369 DNA Cell Biol 1991; 10:505 FEBS Lett 1991; 294:113 BBRC 1990;, 166:336 Jpn J Cancer Res 1991; 82:1413 Jpn J Cancer Res 1991; 82:1413 Jpn J Cancer lies 1991; 82:1413 Jpn J Cancer Res 1991; 82:1413 Jpn J Cancer Rea 1991; 82:1413 Jpn J Cancer Ros 1991; 82:1413 Jpn J Cancer Res 1991; 82:1413 Jpn J Cancer Res 1991; 82:1413 BBRC 1991; 181:121 Mol Cell Endoerinol 1990; 72:201 J Biol Chem 1990; 265:19932 refiOtt, Development 1991; 111:1097 ref:Ott, Development 1991; 111:1097 PNAS 1991; 87:1989 Cell 1990; 62:187 refiBuchberg, Nature 1990; 347:291 J Biol Chem 1990; 265:19065 J Biol Chem 1990; 265:19065 J Biol Chem 1990; 265:19065 J Biol Chem 1990; 265:19065 J Biol Chem 1990; 265:19065 Neuron 1992; 8:241 Neuron 1992; 8:241 ref:Lyons, J Biol Chem 1992; 267:6370 refiLyous, J Biol Chem 1992; 267:6370 refiCordes, E u r J Cell Biol 1991; 55:31 Oncogene Res 1987; 1:129 PNAS 1991; 88:10629 EMBO J 1988; 7:1411 PNAS 1991; 88:144 refiRutherford, Nucl Acid Res 1991; 19:1917 EMBOJ 1988; 7:1411 ref.'Rutherford, Nucl Acid IRes 1991; 19:1917 ref:Ghosh, J Biol Chem 1991; 266:15293 ref.'Ghosh, J Biol Chem 1991; 266:15293 BBRC 1990;, 173:246 Nucl Acid Res 1990; 18:1634 Mol Brain Rea 1990; 8:319 PNAS 1989; 86:4392 Continued on next page

J.T. Eppig: Clones and Probes

424 Table 3. Continued. Chr Symbola

? ? ? ? ? ?

LocusName

Probeb

RFLVc C o n t ~

Helaakoski Pihlajaniemi Helaakoski poly A binding protein clone p5 Rhyner "Pabp" co:A Matsukage Pcna proliferating cell nuclear antigen Pcna genomic co:A Matsukage Pcna-ps 1 proliferating cell nuclear antigen, pseudo-1 Pcna-psl genomic Pcp-4 Pm'kinje cell protein-4 pcp4 cDNA co:HT Orr peptidyl arginine deiminase [R]~.PAD3 + Maruyama Pdi ~PAD1 Tsuchida Pea-3 polyomavirus enhancer activator 3 ZPEA3.1, ),PEA3.9 Xin placentae and embryo oncofetal gene clone 20.2 MacLeod Peru plasmacytoma expressed gene-1 "Pex-l" done 251 Timblin "Pex-2" plasmacytoma expressed gene-2 clone 289 Timblin "Pex-3" plasmacytoma expressed gene-3 clone 326 Timblin Pfn profllin (macrophage) Pfn-cDNA Widada "Pgh" prostaglandin endoperoxide synthase ~.-5, ~.-12A, %-2.5, %-6.6 Kraemer Pgk-lps? Pgk-1 related sequences B6, BS, B13 Adra Phkg phosphorylase kinase T subunit v/-Phk3,pT-Phk9,pT-Phk2 Chamberlain "Pif4a" protein synthesis initiation factor 4A FA1, FA2 Reddy Pif4a genomic clones Nielsen "Pif-4aps Pif-4a pseudogenes clones A,B,C,E,F,G,H,I,J Nielsen "Pif-4ar" Pif-4a retroposon clone D Nielsen "Pif-4a-2" protein synthesis initiation factor 4A-II Pif-4a-2 genomic clones Nielsen Pkcb-2 protein kinase C, ~2 subunit clone 51-1, clone 53-1 Tang Pkcd protein kinase C, 8 subunit Pkc5 probe Ono Wada Pkcd cDNA co:JF Mushinski kMPKD2,~.MPDK5,~.MPDK6 co:S Ohno Pkce protein kinase C, s subunit Pkcs probe (203 to 2168) Ohno Wada Pkcz protein kinase C, ~ subunit Pkc~ probe Ono Wada Plaur plasminogen activator receptor, urokinase type mPAR1, mPAR2 Kristensen Pmv-32 polytropic murine leukemia virus-32 JS-5 Frankel Pmv-52 polytropic murine leukemia virus-52 JS-5 + Frankel Pmv-55 polytropic murine leukemia virus-55 JS-5 + Frankel Pmv-64 polytropic murine leukemia virus-64 JS-5 + Frankel Pmv-67 polytropic routine leukemia virus-67 JS-5 Frankel Pndr pronatriodilatin receptor ML-4.1 Pandey Ppar peroxisome proliferator activated receptor clone 3, clone 54 co:S Green Ppllr placental protein 11 related clone 30 Baughman "Pgerep3" prostaglandin E receptor EP3 subtype MP660 Sugimoto Ppgb protective protein for ~-galactosidase ~.T2, kB1 Galjart pancreatic polypeptide rnPP1, m P P 2 co:J Okamote PpY Prf-1 perforin-1 ps2413,ps 1.8c8,ps2.9 Lowrey Prf c D N A co:K Okumura Prg proteoglycan secretory granule cDNA-M5,cDNA-M6,cDNA-M7 Avraham kMG-PG1 co:S Awaham [R] cDNA-R4 Avraham CPGM Angerth Prkar2b protein kinase, cAMP-dependent, RIII3 genomic Singh regulatory, type II, Prps- 1 phesphoribosyl pyrophosphate synthetase-1 [R]pPRSI-15, [R]pPRSI-24 T a i r a Prps-2 phosphoribosyl pyrophesphate synthetase-2 [R]pPRSII-1 Taira "Ptb" polypyrimidine tract binding protein pNF49R1.0,pNF49R2.0,TNF49 Bothwell "Q300" Q300 gene; carries high affinity SV40 binding site ~.-201, pUC4.2 co:R Knippers rac- 1 ras-rolated C3 botulinum substrate 1 racl cDNA co:H VanderPutten rac-2 ms-related C3 botulinum substrate 2 EN-7 co:G Rovera "Rahl" rah class, ras superfamily gene-1 Rahl cDNA co:DE Koshland, Jr "Raps" receptor assocated protein at synapses M27, M19, M5 co:JP Merlie "Rdsp" r D N A spacer Mr974 Grummt Mr974, pBRMrA, pBRMrE co:I Grummt pMrA Kuhn "Rdspl" nontranscribed rDNA spacer-1 tauNTS1 Wegner "Rdsp2" nontranscribed rDNA spacer-2 tauNTS2 Wegner Rex- 1 reduced expression-1 ~2-5 Hosler pRex239-gem3, pRex-gem Rogers pRex656-geml Rogers "RFM-R" solitary MuLV LTR from RFM/Un pRFM2 Kuemmerle pRFM7,pRFM8 Kuemmerle pRFM1, pRFM3, pRFM4, Ch'ang pRFM6,pRFM9, pRFMll, C h ' a n g pRFM12,pRFM16,pRFM 17 C h ' a n g "RFM- Rf' RFM-R flank from pRFM7 probe 7A, 7B + Kuemmerle "RFM-Rf2" RFM-R flank from pRFM8 prube 8A, 8B + Kuemmerle Rn4.Ss 4.5S rRNA variant clones WJ,CS,D6,X4,27,19 co:LA Leinwand Rn5s 5S rRNA variant 5S rRNA Frederiksen P4hb

proline 4-hydroxylase, ]3 polypeptide

[H] S-138

Ref~mcee

J Biol Chem 1990; 265:11413 EMBO J 1987; 6:643 J Bid Chem 1990; 265:11413 J Neurosci Res 1990; 27:144 refiYamaguchi, Nucl Acid Res 1991; 9:2403 refiYamaguchi, Nud Acid Res 1991; 9:2403 refiChen, Nucl Acid Res 1990; 18:1304 Mouse Genome 1991; 89:278 Agric Biol Chem 1991; 55:295 Genes & Dev 1992; 6:481 Develop Biol 1990; 141:451 Nucl Acid Res 1990; 18:1587 Nud Acid Res 1990; 18:1587 Nucl Acid Res 1990; 18:1587 Nud Add Res 1989; 17:2855 Arch Biochem Biophys 1992; 293:391 Somatic Cell Mol Genet 1988; 14:69 PNAS 1987; 84:2886 Gene 1988; 70:231 EMBO J 1988; 7:2097 EMBO J 1988; 7:2097 EMBO J 1988; 7:2097 EMBO J 1988; 7."2O97 Nud Acid Res 1990; 18:5310 J Bid Chem 1988; 263:6927 BBRC 1989;, 165:533 ref.'Mischak, Biochemistry 30:7925 refiMizuno, Eur J Biocbem 1991; 202:931 Cell 1988; 53:731 BBRC 1989;, 165:533 J Biol Chem 1988; 263:6927 BBRC 1989;, 165:533 J Cell Biol 1991; 115:1763 J Virol 1989; 63:3810 Mamm Genome 1992; 2:110 Mamm Genome 1992; 2:110 Mamm Genome 1992; 2:110 Genetics 1990; 124:221 J Biol Chem 1990; 265:12342 Issemann, J Steroid Bioch Mol Biol 1991;40:263 Mol Endocrinol 1991; 5:637 J Biol Chem 1992; 267:6463 J Biol Chem 1990; 265:4878 ref:Yonekura, J Biol Chem 1988; 263:2990 PNAS 1989; 86:247 ref:Shinkai, Nature 1988; 334:525 PNAS 1989; 86:3763 ref:Stevens, Biochem Soc Trans 1990; 18:810 PNAS 1989; 86:3763 Gene 1990; 93:235 BBRC 1991; 178.'221 Biochem Biophys Acta 1989; 1007:203 Biochem Biophys Acta 1989; 1007:203 J Biol Chem 1991; 266:24657 reflWagner, J Virol 1991; 65:3259 refiMoll, Oncogene 1991; 6:863 reflSbirsat, Oncogene 1990; 5:769 refiMorimoto, Genes & Devel 1991; 5:2386 ref:Frail, J Bid Chem 1988; 263:15602 Nucl Acid Res 1979; 6:1351 ref:Thiry, Nucl Acid Res 1991; 19:11 EMBO J 1987; 6:3487 Nucl Acid Res 1989; 17:9909 Nud Acid Res 1989; 17:9909 Mol Cell Biol 1989; 9:5623 Development 1991; 113:815 Development 1991; 113:815 Virology 1987; 160:379 Virolqgy 1987; 160:379 Virology 1989; 168:245 Virology 1989; 168:245 Virology 1989; 168:245 Virology 1987; 160:379 Virology 1987; 160:379 rof:Kraft, Genomics 1992; 12:555 Nuc Acid Res 1990; 18:7441 Continued on next page

425

J.T. Eppig: Clones and Probes Table 3. Continued. Chr Symbola

9 9 ? 9 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?

? ? ? ? ? ? ? ? ? ? ? ? ? ?

"Rn7sk" "Rnl8s" Rnr-? Rnr-7 Rnr-? Rnr-? Rnr-? Rnu? Rnu? Rnul-ps2 Rnula-ps

I.aces Name

7SK RNA and flank 18S rRNA variant ribosomal RNA ribosomal RNA ribosomal RNA (E VrDNA frag, BALB/c) ribosomal RNA (G VrDNA frag, BALB/c) ribosomal RNA (VrDNA, M molossinus) U1 small nuclear RNA, brain specific U1 small nuclear RNA, brain specific U1 small nuclear RNA pseuclogene-2 U1 small nuclear RNA-la psuedo

Probeb

RFLVc Coal~ctd

7SK genomic, 7SK-PCR N29, N14, N1, NN10 SALE, SALB, PP Mr974, pMR974 clone B1 clones B2, B3 clone M1, M 2 XAB3118 ZAB1290 unnamed + pUP325 pUl-pe325 pUlb-136 pUP136 pUP453, pUP550 pUP550 U2.47, p16-41 U 3 A genomic clone clone 52, pmU6-52

Moon Oberbaumer Bourbon Grummt Sasaki Sasaki

Sasaki Kobayashi Anzai B]att Michael Howard Rnulb-2 U1 small nuclear RNA-lb2 Howard Michael Michael Rnulb-6 U l b l small nuclear RNA Blatt Moshier Rnu2 U2 small nuclear RNA Mazan Rnu3a U3A small nuclear RNA Yuan Rnu6 U6 small nuclear RNA Ohshima clone 34, clone 55, clone 22 O h s h i m a kMU7 Phillips "Rnu7" U7 small nuclear R N A MMU7.B21 Gruber MMU7.14, MMU7.15 Gruber "Rnu7-ps 1" U7 small nuclear RNA, psuedogene-1 "Rnu7-ps2" U7 small nuclear RNA, psuedogene-2 MMU7.23 Gruber "Ro-myl-ps" Ro R N A family, my-1 like 1.3kb genomic Crouch Rpa c D M A Nakagawa "Rpa" replication protein A Rpl7-psl ribosomal protein L7 pseudogene-1 L7-18 Meyuhas Rpll8 ribosomal protein L18a A19 co:L Piko RpI19 ribosomal protein L19 eDNA 11-5 Nakamura cCL3 Belhumeur Rpl27 ribosomal protein L27 krp 1,pUCrpBgl,pUCrpE co J a c k s Rpl32-ps ribosomal protein L32 pseudogene (includes up to 15 pseudogenes) RPL32-3A, RPL32-4E, Dudov RPL32-4A, RPL32-SC, Dudov RPL32-5A, PRL32-6B, Dudov p3AR2.8, p3AH3.4, Dudov p3ARB3.7, p4AJ~.5, Dudov p4AB I4.5,p4AJL2.2,PL32/33 Dudov Rpo3-1 RNA polymerase IIl p71 Gallant "Rpr" 45S pre~rRNA promotor pMr6000 Kuhn Rp~6 ribosomal protein $6 unnamed Lalanne Rpsl2 ribosomal protein S12 S12-cDNA Ayane "Rpsl5" ribosomal protein S15 (rig) B16 co:L Piko co:L Piko Rpsl6-ps ribosomal protein S16 pseudogene S16a, S16b, $16p, S16 eDNA W a g n e r Rps24 ribosomal protein $24 pad-5 Ro "R r" R repeat pMR290 Bennett Flores "Rsk-l" ribosomal $6 kinase, form 1 Mu6a Alcorta "Rsk-2" ribosomal $6 kinase, form 2 Mu7a Aleorta Rxra rotinoid X receptor alpha mRXRa co:RM Evans Rxrb retinoid X receptor beta mRXR]3 co:RM Evans Rxrg retinoid X receptor g a m m a mRXRT co:RM Evans Scd-1 stearoyl-CoA desaturase-1 pAL122 Bernlohr kE1, ~.E2, kE3, XSI Ntambi pC3, pC4, ~ Ntambi clone 279 Weiner Sod-2 stearoyl-CoA desaturase-2 ~32, ~53, ~$18 Kaestner kE14 Ntambi "Scp-2" sterol carrier protein-2 (liver) pMS1, pMS10, pMS20, pMS30 Moneecchi "Sepi" secretory protease inhibitor Sepi genomic Needham "Serpi" serine protease inhibitor (retinoie acid inducible) J6, pc4-6, peG14 Wang "Ski-tg" ski oncogene transgene [C] AFB29 eDNA Sutrave "SmN" RNA splicing protein, S t u n S t u n eDNA eo:DS Latchman Smstr-1 sematostatin receptor 1 SSTR1 genornic Yamada Smstr-2 somatostatin receptor 2 SSTR2 genomic Yamada Spi-2rsl serine protease inhibitor-2 related seq-1 (contrapein-like) %MC-2 eo:Y Ikehara "Spi-2.2" serine protease inhibitor (may = h u m a n AACT) EB22/4 Inglis "Spi-2.3" serine protease inhibitor (similar to rat Spi3) EB22/3 Inglis Srev-1 SWR/J-RF/J ecotropic provirus-1 pBWS0 Spense Srev-2 SWPJJ-RF/J ecotropic provirus-2 pBWS0 Spense Srev-3 SWR/J-RF/J ecotropic provirus-3 pBWS0 Spense Srev-4 SWR/J-RF/J ecotropic provirus-4 pBWS0 Spense Srev-5 SWPJJ-RF/J ecotropic provirus-5 pBWS0 Spense Srov-6 SWPJJ-RF/J ecotropic provirus-6 pBW50 Spense Srev-7 SWR/J-RF/J ecotropic provirus-7 pBWS0 Spense

lh~feomcee

DNA Cell Biol 1991; 10:23 Nuc Acid Res 1992; 20:671 DNA 1988; 7:181 N u d Acid Res 1979; 8:1351 Mol Biol Evol 1987; 4:591 Mol Biol Evol 1987; 4:591 Mol Biol Evol 1987; 4:591 Nuel Acid Res 1988; 16:360 J Neurochem 1986; 47:63 Somatic Cell Mol Genet 1988; 14:133 Somatic Cell Mol Genet 1986; 12:215 Nucl Acid Res 1986; 14:9811 Nucl Acid Res 1986; 14:9811 Somatic Cell Mel Genet 1986; 12:215 Somatic Cell Mol Genet 1986; 12:215 Somatic Cell Mol Genet 1988; 14:133 Gene 1987; 58:19 FEBS Le~ 1990;, 267:121 Mol Biol Rpt 1989;, 13:159 N u d Acid Res 1981; 9:5145 Nucl Acid Res 1981; 9:5145 N u d Acid Rea 1991; 19:1344 Biochim Biophys Acta 1991; 1088:151 Biochim Biophys Aeta 1991; 1088:151 Biochim Biophys Acta 1991; 1088:151 N u d Acid IRes 1989; 17:4890 N u d Acid Res 1991; 19:4292 J Biol Chem 1990; 265:11465 tel:Taylor, Mol Reprod Devel 1992; 31:182 DNA Cell Biol 1990; 9:697 Nucl Acid Res 1987; 15:1019 Gene 1988; 74:565 Cell 1984; 37:457 Cell 1984; 37:457 Cell 1984; 37:457 Cell 1984; 37:457 Cell 1984; 37:457 Cell 1984; 37:457 Mol Biol Rpt 1987; 12:49 EMBO J 1987; 6:3487 Nucl Acid Res 1987; 15:4990 N u d Acid Res 1989; 17:6722 ref:Taylor, Mol Reprod Devel 1992; 31:182 ref:Taylor, Mol Reprod Devel 1991; 28:319 Mol Cell Biol 1985; 5:3560 Nucl Acid Res 1991; 19:6647 Mol Cell Biol 1984; 4:1561 Plasmid 1987; 17:257 Mol Cell Biel 1989; 9:3850 Mol Cell Biol 1989; 9:3850 ref:Mangelsdorf, Genes Dev 1992; 6:329 ref:Mangelsdorf, Genes Dev 1992; 6:329 ref:Mangel~lorf, Genes Dev 1992; 6:329 PNAS 1984; 81:5468 J Biol Chem 1988; 263:17291 J Biol Chem 1988; 263:17291 J Biol Chem 1991; 26623525 J Biol Chem 1989; 264:25 J Biol Chem 1988; 263:17291 J Biol Chem 1991; 266:9885 Nucl Acid R ~ 1988; 16:6229 J Biol Chem 1990; 265:15818 Genes & Develop 1990; 4:1452 ref.'Gerrelli, Nucl Acid Res 1991; 19:6642 PNAS 1992; 89251 PNAS 1992; 89:251 refiOhkubo, Biochem J 1991; 276:337 Gene 1991; 106:213 Gene 1991; 106:213 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 0:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

426 Table 3, Continued. Chr Symbola

~

? ? ? ? ? ? ? ? ? ? ? ? ?

SWPJJ-RF/J ecotrepic provirus-8 SWR/J-RF/J ecotropic provirtm-9 SWR/J-RF/J ecotropic provirus-1O SWPJJ-RF/J ecotropic previrus-ll SWR/J-RF/J ecotropic proviros-12 SWPJJ-RF/J ecotrepic previrus-13 SWR/J-RF/J ecotrepic previrus-14 SWR]J-RF/J ecotropic provirus-15 SWPJJ-RF/J ecotrepic provirus-16 SWR/J-RF/J ecotropic provirus-17 SWR/J-RF/J ecotropic provirus-18 seryl-tRNA syntetase tumor transplantation antigen 91A

? ? ? ? ? ? ? ? ?

? ? ? ? ? ? ? ? ? ? ? ? ?

? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 7 ?

Srev-8 Srev-9 Srev-10 Srev- 11 Srev-12 Srev-13 Srev-14 Srev-15 Srev-16 Srev-17 Srev-18 "Strs" ~Ta-P91A"

Name

Probeb

RFLVc Contactd

pBWS0 Spense pBWSO Spense pBWS0 Spense pBWS0 Spense pBWS0 Spense pBWS0 Spense pBWS0 Spense pBWS0 Spense pBW50 Spense pBWS0 Spense pBWS0 Spense Serr e D N A co:LI Slobin P91A-6.8, P91A.5, Lurquin C91.2, C91.7, C91.2.1 Lurquin Taclr taehykinin 1 receptor cesSPR1, cesSPR2, cesSPR5 Sundelin Tac2r tachykinin 2 receptor cesSKR1, cesSKR2, cesSKR3 Sundelin "Tau" Tau protein pTA1, pTA2 Drubin pTA2E, pTA3, Lee pTA3E, pTA2E' Lee "Tb- 1" trophoblast specificgene-1 clone 4311 Lescisin "Tcm-l" T-cell mediator (unknown function) 4-1BB (L3G29#4) Kwon Tcfcp2 transcription factorCP2 CP2 eDNA co:M Sheffery Tcfpul transcription factorPU.1 W25.35.1, k24.1, k25.1 Klemsz m5.1, m5.2, m5.3, m5.4, co:ML Atchison m5.5, m5.6, m5.7, m5.8 co:ML Atchison "Tcf-UBF"transcription factor UBF ~.UBFb-2, kC7, kC9, eo:M M u r a m a t s u G7, G8, G13, G6 co:M M u r a m a t s u "Tcrpf" T-cell replacing factor 8-1R Kwon "Ten" tenascin clones 3, 42, 4, 44, 54, 6, Saga clones 57, 56, 74, 76, 61 Saga "Tg-413.d" transgenic lethal 413.d pSS1/1 co:EJ Robertson "Tg-Mpvl7" Mpvl7 transgene, kidney disease mutant ~M 12.1,kM 10.0,kM421.1,H 1.5 Wether Mpvl7 wild-type insertion site kWlS.2,p041,p052,p142,p211 W e i h e r "Tgl" transglutaminase, tissue TGHZ3 Gentile Thbd thrombomodulin Thbd cDNAs Dittman clone Pl12.1, clone 15Ab.2 co:SJ Kennel Thral thyroid hormone receptor a-1 Thral c D N A Masuda clone A, clone B, cloneC Wood a l eDNA Prest Thra2 thyroid hormone receptor a-2 clone D, clone E Wood a2 eDNA Prest Thrbl thyroid hormone receptor ~-1 clone F, clone G Wood dine 9 co:S Green Thrb2 thyroid hormone receptor ~-2 clone H Wood "Thym" thymesin a pMTHY co:D Werner "Tie-4" TPA-inducible early gene-4 TIE-4 Amagai "Tie-10b" TPA-inducible early gene-10B TIM-10B Arnagai "Tie-44" TPA-inducible early gene-44 TIE-44 Arnagai "Ti f" tissue factor c70 Ranganathan [RAB] pRTF1 Andrews Tis TPA-induced sequences TIS eDNAs Tippetts "Tis-l" TPA-induced sequence- 1 TIS1 cDNA Tippetts "Tis-7" TPA-induced sequence-7 TIS7 eDNA Tippetts "Tis-8" TPA-induced sequence-8 TIS8 eDNA Tippetts "Tis-10" TPA-induced sequence-10 TIS10 eDNA Tippetts "Tis-ll" TPA-induced sequence-11 T I S l l cDNA Tippetts "Tis-21" TPA-induced sequence-21 TIS21 eDNA Tippetts Tk-ps 1 thymidine kinase pseudogene 1 TK cosmid C co:E Wintersberger Tk-ps2 thymidine kinase pseudogene 2 Tk-ps2 genomic co:E Wintersberger Tlm T-lymphoma oncogene Tlm DNA Lane Tncc troponin C cardiac/slow skeletal cTnC cNDA, MGcTnC7 Parmacek cTnc eDNA Parmacek Tncs troponin C, fast skeletal sTne eDNA,sTne genomic Parmacek Tp-2 transition protein-2 pMTP2-1, pMTP2-2 Kleene Tp-2 genomic Kleene Tpm-2 tropomyesin-2 beta [isoform 2] "1"33 Takenaga ~ 7 MaeLeod "Tmp-5" tropomyesin 5 T19 Takenaga "Tps- 1" tumor promoter sensitive gene pHA Lerman pRG-11, P3R, P2R Garrity Trapla turnerrejection antigen PIA CIA.3.1, PIA e D N A co:T Boon "Trfr" transferrinreceptor 2.6kb eDNA, 3.9kb c D N A Stearne Trhr thyrotropinreleasing hormone receptor THR-R eDNA Straub "Try-2" trypsinT b k~IT5 Stevenson "Try-3" trypsinT d ~.MT2 Stevenson

Ref~ce e

Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 Mol Cell Biol 1989; 9:177 ref:Miseta, J Biol Chem 1991; 266:19158 Cell 1989; 58:293 Cell 1989; 58:293 Eur J Biochem 1992; 203:625 Eur J Biochem 1992; 203:625 J Cell Biol 1984; 98:1090 Science 1988; 239:285 Science 1988; 239:285 Genes & Devel 1988; 2:1639 PNAS 1989; 86:1963 ref:Lim, Mol Cell Biol 1992; 12:828 Cell 1990; 61:113 ref:Mel Cell Biol 1992; 12:368 ref:Mol Cell Biol 1992; 12:368 ref:Hisatake, Nucl Acid Res 1991; 19:4631 ref:Hisatake, Nucl Acid Res 1991; 19:4631 PNAS 1989; 86:1963 Gene 1991; 104:177 Gene 1991; 104:177 ref:Conlon, Development 1991; 111:969 Cell 1990; 62:425 Cell 1990; 62:425 J Biol Chem 1991; 266:478 Nucl Acid Res 1989; 17:802 ref:Ford, J Biol Chem 1992; 267:5446 Nucl Acid Res 1990; 18:3055 Molec Endocrinol 1991; 5:1049 N u d Acid Res 1988; 16:6248 Molec Endocrinol 1991; 5:1049 N u d Acid Res 1988; 16:6246 Molec Endocrinol 1991; 5:1049 Issemann, J Steroid Biech Mol Biol 1991;40:263 Molec Endocrinol 1991; 5:1049 ref:Schmidt, Bitch Biophys Acta 1991; 1088:442 Som Cell Mol Genet 1989; 15:153 Som Cell Mol Genet 1989; 15:153 Som Cell Mol Genet 1989; 15:153 J Biol Chem 1991; 266:498 Gene 1991; 98:265 Mol Cell Biol 1988; 8:4570 Mol Cell Biol 1988; 8:4570 Mol Cell Biol 1988; 8:4570 Mol Cell Biol 1988; 8:4570 Mol Cell Biol 1988; 8:4570 Mel Cell Biol 1988; 8:4570 Mol Cell Biol 1988; 8:4570 Seiser, Nucl Acid Res 1989; 17:185 Seiser, N u d Acid Res 1989; 17:185 N u d Acid Res 1990; 18:3410 J Biol Chem 1989; 264:13217 J Biol Chem 1990; 265:15970 J Biol Chem 1990; 265:15970 J Biol Chem 1987; 262:17272 Gene 1990; 95:301 Mol Cell Biol 1988; 8:5561 Mol Cell Biol 1988; 8:433 BBA 1990; 1987:101 Int J Cane Res 1986; 37:293 Gene 1988; 68:63 ref:Van de Eynde, J Exp Med 1991; 173:1373 J Immuaol 1985; 134:3474 PNAS 1990; 87~514 Nucl Acid Res 1986; 14:8307 Nucl Acid Res 1986; 14:8307 Continued on next p a g e

J.T. Eppig: Clones and Probes

427

Table 3. Continued.

Chr Sym~a

L o ~ Name

Prd~

? ? ? ? ?

'Try-3,-4" trypsin Te,T d "Try-5" trypsin T o "Tsga" testis temporal specific cell active gone Tst-1 testes-1 Ttr transthyretin

?

Tuba-1

tubulin a l

?

Tuhb

tubulin ~

?

Tyros

thymidylate synthase

? ?

Tyms-ps "U31tr"

thymidylate synthase pseudogene U3 ecotropic LTR

? ?

"Ubi" Utg

uhiquitin uteroglobin

? ? ? ? ? ?

Vcam-1 Vcl "Vie" Vip Vsp Wap

vascular cell adhesion molecule-1 vinculin vasoactive intestinal contractor vasoactive intestinal polypeptide vasopressin whey acidic protein

Xmmv-43 Xmmv-44 Xmmv-45 Xmmv-46 Xmmv-47 Xmmv-48 Xmmv-49 Xmmv-51 Xmmv-53 Xmmv-54 Xmmv-56 Xmmv-57 Xmmv-58 Xmmv-59 Xmmv-60 Xmmv-63 Xmmv-64 Xmmv-66 Xmmv-68 Xmmv-69 Xmmv-70 Xmmv-78 Xmv-6 Xmv-23 Xmv-29 Xmv-39 Xmv-56 "Yes" "Ypt-l"

xenotropic-MCF leukemia virus-43 xenotropic-MCF leukemia virus-44 xenotropic-MCF leukemia virus-45 xenotropic-MCF leukemia virus-46 xenotropic-MCF leukemia virus-47 xenotropic-MCF leukemia virus-48 xenotropic-MCF leukemia virus-49 xenotropic-MCF leukemia virus-51 xenotropic-MCF leukerma virus-53 xenotropic-MCF leukemia virus-54 xenotropie-MCF leukemia virus-56 xenotropie-MCF leukemia virus-57 xenotropic-MCF leukemia virus-58 xenotropic-MCF leukemia virus-59 xenotropic-MCF leukemia virus-60 xenotropic-MCF leukerma virus-63 xenotropic-MCF leukenua virus-64 xenotropic-MCF leukemia virus-66 xenotropie-MCF leukerma virus-68 xenotropic-MCF leukerma virus-69 xenotropic-MCF leukemia virus-70 xenotropie-MCF leukemia virus-78 xenotropic murine leukemia virus-6 xenotropic murine leukemia virus-23 xenotropic murine leukemia virtm-29 xenotropie murine leukemia virus-39 xenotropie murine leukemia virus-56 Yes oncogene ypt-1 ras-rolatod GTP-binding protein

Zfp-5 Zfp-7 Zfp-8 Zfp-9

zinc zinc zinc zinc zinc zinc zinc zinc zinc zinc zinc

Zfp-lo Zfp-11 Zfp-12 Zfp-13 Zfp-14

Zfp-15 Zfp-16

finger finger finger finger finger finger finger finger finger finger finger

protein-5 protein-7 protein-8 protein-9 protein-10 protein-ll protein-12 protein-13 protein-14 protein-15 protein-16

RELYc C~t~-~

~,MT9 XMT12 TSGA-3', TSGA-5' Tst-1 eDNA (PCR) Ttr eDNA, Ttr genomic

Stevenson Stevenson Hoog Zimmerman Wakasugi Wakasugi " Shimada [R] u n n a m e d Lemisehka " Schnieke LG-69 co:AB Pardee [C] ~ tubuiin eDNA Cleveland " Johnson [C] pT2 co:S Ross pn~5 co:D Cleveland TSB-9, TSB-16, Deng TS-PPH-1, pMTS-3 Deng pMTS-1, pMTS-2, pMTS-4 Geyer pESIBI31 DeWille TX-4 Li U3LTR-MuLV Quint Mucenski U31tr gonomic Khan 3JSF, p-real-3 Finch [RAB] Utg eDNA co:M Beate [R] Utg eDNA co:M Beate VCAM1 eDNA Hession Vcl eDNA Ben-Ze'ev Vie cDNA eo:Y Mitsui Vip genomic co:L Villa-Komaroff X3.3.1, k4.1.1 Hara pWAP1, pWAP2 Hennighausen pXMI-14 Gupta ~.WAP24 Campbell Wap genomic,pUC 18/5'Wap co:Henninghauser + co:MA Martin pXenv pXenv + co:MA Martin pXenv + co:MA Martin pXenv + co:MA Martin + co:MA Martin pXenv pXenv + co:MA Martin + eo:MA Martin pXcnv pXenv + co:MA Martin pXenv + eo:MA Martin pXenv + co:MA Martin pXenv + co:MA Martin pXenv eo:MA Martin pXcnv + co:MA Martin pXenv + co:MA Martin pXenv + co:MA Martin pXenv + eo:MA Martin pXenv + eo:MA Martin pXenv + eo:MA Martin pXenv + eo:MA Martin pXenv + eo:MA Martin pXenv eo:MA Martin pXenv, pMo-MCFenv + Frankel JS-6+JS-IO + Frankel JS-6+JS-IO Frankel JS-6+JS-IO Frankel JS-6+JS-IO Frankel JS-6+JS-10 + Frankel clone100 Dymecki F9-104, F9-12, Haubruck pcD-YPT82, pcD-YPT71 Haubruck pEV-GALmypt- 1 Haubruek yptl-genomic Wichmann LI36, ~2G, kH31, kMSE Kinzler phage 2.1,2.2 Chavmer Chavrier phage 3 phage 4.1,4.2,4.3 Chavmer Chavrier phage 5 Chavrler phage 6.1,6.2,6.3 phage 7.1,7.2 Chavrier Chavrier phage 8 phage 9.1,9.2,9.3 Charmer phage 10 Chavrier Chavrier phage 11

Nuel Acid Res 1986; 14:8307 Nuei Acid Res 1986; 14:8307 Mol Reprod Devel 1991; 30:173 Nucl Acid Res 1991; 19:956 J Biol Chem 1985; 98:1707 J Biochem 1986; 100:49 Mol Biol Med 1989; 6:333 J Mol Biol 1981; 151:101 Nature 1983; 304:315 ref:Nikaido, Exp Cell Res 1991; 192:102 Cell 1980; 20.~5 Exp Cell Res 1990; 187:69 ref:Fukumote, Sore Cell Mol Gen 1986; 12:611 ref:Rienhoff, Mol Cell Biol 1988; 8:3710 J Biol Chem 1986; 261:16000 J Biol Chem 1986; 261:16000 J Biol Chem 1984; 25~.7206 J Biol Chem 1988; 263:84 Gene 1989; 82:363 J Virol 1984; 50:432 J Virol 1987; 61:2929 Nucl Acid Res 1987; 15:7640 Nucl Acid Res 1990; 18:1907 ref:Sandmoller, Mech Devel 1991; 34:57 ref:Sandmoller, Mech Devel 1991; 34:57 BBRC 1992; 183:163 Cell Regulation 1990; 1:621 rel~Saida, BBA 1991; 1989:404 ref:Lamperti, Mol Brain Res 1991; 9:217 Mol Brain Res 1990; 8:319 Nucl Acid Res 1982; 10:2677 J Cell Biol 1982; 93:199 Nucl Acid Res 1984; 12:8685 ref:Schoenenberger, EMBO J 1988; 7:169 ref:Wejman, J Virol 1984; 50:237 rof:Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref.'Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref.'Wejman, d Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref.'Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref.'Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 refiWejman, J Virol 1984; 50:237 ref:Wejman, J Virol 1984; 50:237 M a m m Genome 1992; 2:110 M a m m Genome 1992; 2:110 J Virol 1989; 63:1763 J Virol 1989; 63:1763 J Virol 1989; 63:1763 M a m m Genome 1992; 2:110 Science 1990; 247:332 EMBO J 1987; 6:4049 EMBO J 1987; 6:4049 EMBO J 1989;, 8:1427 Nuci Acid Res 1989; 17:6737 Nature 1988; 332:371 Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Moi Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 C o n t i n u e d on next p a g e

J.T. Eppig: Clones and Probes

428 Table 3.

Continued.

Cbr Syml~la

Locus Name

? ? ? ? ? ? ?

Zfl~17 Zfp-18 Zfp-19 Zfi~20 Zfp-21 Zfl~22 Zfl~23

zinc zinc zinc zinc zinc zinc zinc

? ? ? ? ? ? M

Zfl~24 Zft~26 Zfp-27 Zfp-28 Zfp-29 Zfp-? "BI"

zinc finger zinc finger zinc finger zinc finger zinc finger zinc finger Blrepeat

M

"B2"

B2 repeat

M

"BarnS"

BAM5 repeat

M

"Cen"

centromere repeat seqences

M

"Ecol"

1.3kb EcoRI repeat

M

Emv-?

Emv loci

M

Env-?

env gene (xenotropic)

M M

"Glnf" IAP

GLN retroviral family intracisternal A particles

M

"IAPE"

Intracisternal A particle related retroviral elements

M M M

L1Md L1Md-A2 L1Md-A2

L1 repeat L1 repeat L1 repeat (M. domesticus)

M

L1Md-A13 L1 repeat L1MdF15 L1 repeat

M

finger finger finger finger finger finger finger

Probeb

protein-17 protein-18 protein-19 protein-20 protein-21 protein-22 pretein-23 protein-24 protein-26 protein-27 protein-28 pretein-29 protein-testis expressed

RFLVc C c n t ~

phage 12.1,12.2,12.3 phage 13.1,13.2,13.3 phage 14 phage 15 phage 17 phage 18 phage 20 pEX2.8, AC16 phage 21 mkr3 mkr4 mkr5 pD26, pD28 C2H2 type cDNA pMR225 pMR225, pMR164, pMRll8, pMRS0, pMR131 B1 plasmid p61-41, B1-9, Bl-15 Mm31

Chavrier Chavrier Chavrier Chavrier Chavrier Chavrier Chavrier Chavrier Chavrier Chowdhury Chowdhury Chowdhury co:A Ashworth Nelki Flores Bennett Bennett co:K Bennett Moshier co:Georgiev Jubier-Maurin co:Georgiev pMR142 co:K Lueders Flores co:K Lueders p49C~,p7E4 co:Edwards Gallant pMR142, pMR293 Bennett B2 plasmid co:K Bennett pMBA-14 Keshara Fanning pMR196 Siracusa clone R17 Nishioka pMD006, pMD007 Dubnick pMD335, pMD302, Dubnick pMD350 ,pMD416, Dubnick pMD437, pMD106, Dubnick pMD131, pMD135 Dubnick unnamed Jenkins Chattopadhyay pXenv Bedigian co:Bedigian Buckler MCF247, NZB-IV-6 Hoggan O'Neill B-26 Obata pMIA1 Lueders Kuff MIA14,MIA48 Kuff kMIA2, kNIIA14, kMIA21 Kuff kMIA63, kNIIA48, k-MIA62 Kuff pMIA7, pMIA6, pMIA4 Kuff pMIA1, pMIA2, kMIA2, Lueders kMIA14, kMIA15, kNIIA21, Lueders kMIA58, kMIA63 Lueders IAP plasmid 11 Pike clones 8.3, 9.5, 10.2 Grossman Moore Martens B12,D8,D20, kMIA14, Grossman IAP-genomic Grossman I~l, p3A67 Aota A-81 Cole pl9-B Cole [APE-l, IAPE-0, IAPE-7 Reuss [APE-28, IAPE-4, IAPE-8 Reuss IAPE-10 Reuss 1.35,X Papaconstantinou CE162 Loeb M2-25, M1-27, M2-27, Edgell M2-22, M2-23C, M2-20, M1-25, M2-19 CEl13 Shehee F15 DNA Hutchison IlI

Refem',cee

Mol Cell Biol 1988; 8:1319 Mol Cell Biel 1988; 8:1319 Mol Cell Biel 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Mol Cell Biol 1988; 8:1319 Mol Cell Biel 1988; 8:1319 EMBOJ 1988; 7:29 Mol Cell Biol 1988; 8:1319 Nucl Acid Res 1988; 16:9995 Nucl Acid Res 1988; 16:9995 Nucl Acid Res 1988; 16:9995 refiDenny, Gene 1991; 106:221 Nucl Acid Res 1990; 3655 Plasmid 1987; 17:257 Mol Cell Biol 1984; 4:1561 Mol Cell Biol 1984; 4:1561 ref:Boyle, PNAS 1990; 87:7757 Gene 1987; 56:19 ref:Krayev, Nucl Acid Res 1980; 8:1201 Nucl Acid Res 1967; 15:7395 ref:Nishioka, Cytogen Cell Genet 1989; 50:195 ref:Fukumeto, Sore Cell Mol Gen 1986; 12:611 Plasmid 1987; 17:257 ref:Fukumote, Som Cell Mol Gen 1986; 12:611 Mol Cell Biol 1985; 5:3280 Mol Biol Rpt 1987; 12:49 Mol Cell Biel 1984; 4:1561 tel:Boyle, PNAS 1990; 87:7757 PNAS 1987; 84:3325 N u d Acid Res 1982; 10:5003 J Embryol Exp Morph 1983; 73:163 Cytogenet Cell Genet 1989; 50:195 J Mol Evol 1983; 19:115 J Mol Evol 1983; 19:115 J Mol Evel 1983; 19:115 J Mol Evol 1983; 19:115 J Mol Evol 1983; 19:115 J Viral 1982; 43:26 PNAS 1980; 77:5774 Immunogenetics 1986; 23:156 refiColombo, Oncogene 1988; 2:395 J Viroi 1982; 41:228 J Virel 1986; 60:980 J Virol 1986; 58:359 J Virol 1988; 62:4381 PNAS 1980; 77:3571 Chromesoma 1986; 93:213 PNAS 1986; 83:6583 Mol Cell Biol 1981; 1:216 Mol Cell Biol 1981; 1:216 Mol Cell Biol 1981; 1:216 PNAS 1980; 77:3571 PNAS 1980; 77:3571 PNAS 1980; 77:3571 PNAS 1984; 81:488 Nucl Acid Res 1987; 15:3823 J lmmunol 1986; 136:4283 PNAS 1985; 82:2460 Nucl Acid Res 1987; 15:3823 Nucl Acid Res 1987; 15:3823 Gene 1987; 56:1 J Virel 1981; 38:680 J Virol 1982; 42:123 J Virol 1991; 65:5702 J Virel 1991; 65:5702 J Virol 1991; 65:5702 Nuel Acid Res 1984; 12:6575 Mol Cell Biel 1986; 6:168 Developmental Control of Glebin Gene Expression, Alan R Lies, Inc, p. 107, 1987 J Mol Biol 1987; 196:757

Nucl Acid Res 1991; 19:2497 C o n t i n u e d on n e x t p a g e

J.T. Eppig: Clones and Probes

429

Table 3. Continued. Chr Symbola

M

M M

i

M M M M M M M M M M M M M M M

M M M M M M M

LINE1

Locus Name

L1 repeat

l~beb

pbS18 pMR134 KS13A

RFLVc C~aiac~

Schmeckpeper Voliva Fanning co:T F a n n i n g clones 1G-1 through 1G-!0 Jubier-Maurin 1G-2, pWB55 Wincker clone 1G-6, pWZ63, pWZ31 W i n c k e r clones 4AG-1 through 4.AG-10 Jubier-Maurin pMR290 co:Hastie Jubier-Maurin pBfl~5 co:Fanning Jubier-Maurin L5.8 co:Mottez Jubier-Maurin "LLRep-3" LLRep3 repeat kSB1-2, k8-Bl-1 Heller ~.15c Slynn "Mi fr" MIF repeat pMR134, pMR257 Bennett pMR134 Flores pMR257 Bennett KT4O Nishioka "Mns" minor satellite (eentromeric) pMR150 Voliva co:VM C h a p m a n co:ND Hastie Neuer-Nitsche pEAT 11 pMKB6, pMKC78, Wong pMKC85, pMKCI04 Wong pMKC104 Wong minisatellite pSP64.2.5EI Georges "Ms" too-1 + Kominami "Ms-l" minisatellite 1-Vntr (Drosophila Per) pSP.2.5.EI + Julier detects loci on Chr 2, 4, 5, 8, 9, 12, 13) minisatellite 2-Vntr (human D1S57) "Ms-2" pYNZ2 + Julier detects loci on Chr 1, 2, 3, 4, 7, 8, 9, 12, 17) "Ms-3" minisatellite 3-Vntr (human D3S45) pEFD134.7 + Julier detects loci on Chr 2, 4, 6, 9, 11, 13) "Ms-4" minisatellite 4-Vntr (human D2S44) pYNH24 + Julier detects loci on Chr 1, 4, 5, 7, 9, 12, 13, 14) "Ms-5" minisatellite 5-Vntr pEWRB2.3 + Julier detects loci on Chr 2, 4, 5, 7, 12,13) ~Ms-6" minisatellite 6-Vntr (human D14S1) pAWl01 + Julier detects loci on Chr 2, 3, 4, 5,11,17) "Ms-7" minisatellite 7-Vntr (human RB1) p68RS2.0 + co:T Dryja detects loci on Chr 5, 6, 9, 12, 13, 14, 15) "Ms-8" minisatellite 8-Vntr (human INS) pINS310 + co:G Bell detects loci on Chr 2, 4, 7, 8, 9, 12, 17) "Ms-9" minisatellite 9-Vntr (human D17S28) pYNH37.3 + Julier detects loci on Chr 4) "Ms-10" minisatellite 10-Vntr (human D17S5) pYNZ22 + Julier detects loci on Chr 1, 4, 7, 9, 11, 13,14) "Ms-11" minisatellite ll-Vntr (human D17S24) pRMU3 + Julier detects loci on Chr 2, 3, 9, 14) mouse specific repeat "MSR" pMR35 Levenson MT repeats "Mtr" kM68910-1, kM68910-2 Bastien CebA-847, MT-1, MT-36 Heinlein Mtv-loci m a m m a r y tumor virus locipSC34 (MMTV env) Sharma King 1.5kb Pst LTR frag Huppi Kozak pA7 (MMTV LTR) co:Ostrowski MMTV (GR) kMMTV-GR Buetti MMTV Rep Callahan MMTV (C3H) pMMTV(C3H) Callahan p201 co:Callahan co:Callahan p4.2A co:Majors C 3 H M u M t v 5' L T R co:H Varmus env gene co:H Varmus -?F-MuLV E57BS, clone 57 Sola F-MuLV (env) p0.8 Silver "7" Mo-MuLV p8.2 co:Goff co:Goff -?. MuLV envelope pECen v Chan M u L V specific pC6 Panthier pro-MuLV (RFM) pRFM#6 Nikbakht -?MURRS (murine retrovirus rel seq) MuRRS-1, MuRRs-2 + Schmidt MuRRs-5, MuRRs-6 + Schmidt

R e f ~ e ~e

Nucl Acid Res 1981; 9:1853 Nucl Acid Res 1983; 11:8847 Biochim Biophys Acta 1987; 910:203 refiBoyle, PNAS 1990; 87:7757 Nucl Acid Res 1987; 15:7395 Nucl Acid Res 1987; 15:8593 Nucl Acid Res 1987; 15:8593 Nucl Acid Res 1987; 15:7395 ref:Bennett, EMBO J 1984; 3:467 Nucl Acid R ~ 1987; 15:7395 tel:Fanning, Nucl Acid Res 1983; 11:5073 Nncl Acid Res 1987; 15:7395 refiMottez, Nuel Acid IRes 1986; 14:3119 Nucl Acid Res 1987; 15:7395 Mol Cell Biol 1988; 8:2797 Nucl Acid Rea 1990; 18:681 Mol Cell Biol 1984; 4:1561 Plasmid 1987; 17:257 Mol Cell Biol 1984; 4:1561 Cytogenet Cell Genet 1989; 50:195 Nucl Acid IRes 1983; 11:8847 tel:Broccoli, Cytogenet Cell Genet 1990; 54:182 ref:Pietras, Nucl Acid Res 1983; 11:6965 Nucl Acid IRes 1988; 17:8351 Nucl Acid Res 1988; 16:11645 N u d Acid R ~ 1988; 16:11645 Chromosoma 1990; 99:190 Nucl Acid IRes 1987; 15:7193 Nucl Acid Res 1988; 16:1197 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 rePJulier, PNAS 1990; 87:4585 ref'Julier, PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1990; 87:4585 PNAS 1984; 81:1489 Gene 1987; 57:81 Nucl Acid Res 1986; 14:6403 J Immunol 1988; 141:2510 J Immunol 1990; 144:3218 Curr Top Micro I m m u n 1988;141:652 J Virol 1987; 61:1651 tel:King, J Immunol 1990; 144:3218 Cell 1981; 23.'335 PNAS 1982; 79:4113 PNAS 1982; 79:4113 ref.'Major, Nature 1981, 289:253 refiColombo, Oncogene 1988; 2:395 ref:Traina-Dodge, Genetics 1985; 111:597 refiPathak, JNCI 1987; 78:327 refiPathak, JNCI 1987; 78:327 J Virol 1986; 60:718 J Virol 1986; 57:526 ref:Schwartzberger, J Virol 1983; 46:538 ref:Colombo, Oncogene 1988; 2:395 PNAS 1979; 77:5779 Virol 1987; 138:409 J Gen Virol 1987; 68:683 Nucl Acid Res 1985; 13:3461 Nucl Acid Res 1985; 13:3461 Continued on next page

J.T. Eppig: Clones and Probes

430 Table 3. Continued. Chr Symbaa

~

Name

M M M

Pgk-lps? Pgk-1 related sequences "Rpt(Tu96)" hight copy number repetitive element "Sat" satellite DNA (major)

M

"Satg-"

satellite DNA, major ?

M

"Sped"

M

"VL30"

small polydispersod circular DNA VL30 retrovirus element

Prd~eb

RFLVc C ~ a

clones B6, P,8, B13 Adra Tu96 Nelson p16 co:Fittler pSAT1, pSAT2 Radic pSAT Wong clones 10B, 10C, llD, llG, Vissel clones 2C, 3A, 4A, 10D, 10H, Vissel clones 10I, 10G, 4D, 10A, 816, Vissel clones 9F, 9D, 6A, 4B, 10E, Vissel clones 1A, 4E8, llB, 7A, 7B, Vissel clones 6E, 8H, 8J, 8G, 5A, 8A Vissel pSP (many) Sunnerhagen NVL3/9 Adams pVL47 Courtney clone 1.5 Baughman

Refemmee

Somatic Cell Mol Genet 1988; 14:69 J Mol AppI Genet 1984; 2:563 ref.'Horz, Nucl Acid Res 1981; 9:683 Cell 1987; 50:1101 Chromesoma 1990; 99:190 Genomies 1989; 5:407 Genomics 1989; 5:407 Genomics 1989; 5:407 Genomies 1989; 5:407 Genomics 1989; 5:407 Genomies 1989; 5:407 Nucl Acid Res 1986; 14:7823 Mol Cell Biol 1988; 8:2989 J Virol 1982; 43:511 Mol Endocrinol 1991; 5:637

a Locus symbols enclosed in quotation marks are not standard symbols and will be replaced with approved symbols as they are assigned. Locus symbols followed by "(x)" indicates parts of the gene detected by the probe. Symbols in "( )" are not part of the gene symbol. b Probes and clones are from mouse except where preceded by [B] = bovine; [C] ~ chicken; [CH] = Chinese hamster; [D] = Drosophila; IF] = feline; [HI = human; [Ha] = hamster; [Mk] = mink; [Mp] = Mus pahari; [R] = rat; [RAB] = rabbit; [SH] = Syriam hamster; [Sire] = simian; [V] = virus. Only probes/clones of mouse origin or known to cross-hybridize to mouse are included. c RFLV: known variants for a given probe indicated by " + " in RFLV column. d Contact person. Indicates the first author of the paper, or, when preceded by co, indicates that the probe/clone was obtained from that individual. e If article is preceded by "ref:" the "Contact" is not the first author or the probe was obtained from the "Contact."